Padres vs Brewers Prediction — AI Finds CAN'T MISS MLB Lines & Props (Jun 07)
Updated: 2025-06-05T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Diego Padres travel to American Family Field on June 7, 2025, for a pivotal midseason matchup against the Milwaukee Brewers. Milwaukee enters as the favorite at –149 on the moneyline and –1.5 on the run line, with the total set at 8.5 runs—signaling expectations for a close, strategy-heavy game.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Jun 07, 2025
Start Time: 7:35 PM EST
Venue: American Family Field
Brewers Record: (34-30)
Padres Record: (36-26)
OPENING ODDS
SD Moneyline: -104
MIL Moneyline: -115
SD Spread: -1.5
MIL Spread: +1.5
Over/Under: 8.5
SD
Betting Trends
- San Diego has split run-line decisions evenly over their last ten matchups against the Brewers, going 5–5–0 ATS in head-to-head contests this season.
MIL
Betting Trends
- Milwaukee has gone 6–4 ATS in its last 10 home games, including a strong 3–1 mark as favorites, showcasing consistent value for bettors.
MATCHUP TRENDS
- The Brewers have won 77.8 percent of their games as moneyline favorites of –149 or shorter, while the Padres have won 55.6 percent as underdogs of +125 or worse—creating a dynamic betting environment.
SD vs. MIL
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: J. Chourio over 6.5 Fantasy Score.
LIVE MLB ODDS
MLB ODDS COMPARISON
WANT MORE AI PICKS?
VS. SPREAD
325-240
NET UNITS
(INCL VIG)
+395.4
NET PROFIT
(INCL VIG)
$100/UNIT
$39,540
VS. SPREAD
1593-1364
NET UNITS
(INCL VIG)
+371.9
NET PROFIT
(INCL VIG)
$100/UNIT
$37,192
AI SPORTS PICK PRODUCTS
Create a Free Account

Remi Finds New Picks

Remi Works 24/7
Remi uses this probability to assign units to each pick.
Get Remi's AI Picks
Get Remi’s Top AI Sports Picks sent direct to your inbox.
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
San Diego vs Milwaukee Prediction & Odds:
Free MLB Betting Insights for 6/7/25
The Brewers have gone 6–4 against the spread in their last 10 home games and 3–1 as favorites, indicating consistency when backed by their home crowd and strong bullpen, which remains one of the most effective in the league at converting saves and protecting slim leads. Milwaukee’s offense centers around Christian Yelich and William Contreras, two versatile bats capable of anchoring innings through contact and baserunning more than raw power. Defensively, Milwaukee has played clean baseball, ranking in the top third of the NL in fielding percentage and limiting big innings through sharp infield work and strong outfield range. For the Padres, success will depend on Kolek surviving the first two times through the order and handing a close game to a bullpen that has been lights-out in tight spots, led by a trio of high-leverage arms that can handle both lefties and righties. Offensively, they must cash in on runners in scoring position and avoid the base-running mistakes that have occasionally cost them in close games. Both teams are well-coached, matchup-savvy, and capable of winning one-run ballgames, making every managerial decision from the fifth inning onward potentially game-defining. With each team boasting a different style—San Diego’s patient, grind-it-out offense versus Milwaukee’s aggressive, situationally sharp execution—this game may ultimately turn on one swing, one misplay, or a single high-leverage plate appearance. Expect a playoff-like tone and a game that could come down to a ninth-inning at-bat, with neither team offering much margin for error in a battle that could foreshadow an October rematch.
— San Diego Padres (@Padres) June 7, 2025
San Diego Padres MLB Preview
The San Diego Padres head into Saturday’s matchup against the Milwaukee Brewers carrying a 33–27 record and a growing sense of urgency as they seek to build consistency in a loaded National League Wild Card race. With momentum gained from a string of quality road performances, the Padres will hand the ball to rookie right-hander Stephen Kolek, who has earned increasing trust within the rotation due to his exceptional command, efficient pitch counts, and ability to induce weak contact. Kolek isn’t a strikeout machine, but his knack for working quickly and forcing grounders allows him to keep innings short and hand the ball over to a reliable bullpen that ranks among the best in the National League in ERA and WHIP during late-inning situations. San Diego’s strength lies in its lineup balance, where stars like Manny Machado, Juan Soto, and Xander Bogaerts combine with complementary bats such as Jake Cronenworth and Ha-Seong Kim to generate offense through a patient, contact-first approach. Soto’s eye at the plate remains one of the best in baseball, while Machado continues to produce in clutch spots, providing power from the cleanup spot and leadership in the field. Bogaerts, though less explosive in 2025, remains a key contributor in driving in runners from scoring position and working tough at-bats against top-tier pitching.
The Padres are 5–5 ATS in their last 10 head-to-head games with the Brewers, including a handful of late-game covers thanks to their superior bullpen and late-inning offense. Their challenge on Saturday will be getting to Brewers ace Brandon Woodruff early, as falling behind against Milwaukee’s bullpen can be a death sentence given how efficiently they shut down games once they take the lead. Kolek’s goal will be to keep the game close through five or six innings and limit traffic ahead of Milwaukee’s middle-order hitters like Christian Yelich and William Contreras, who can change the game with one big swing or hustle play. Defensively, San Diego has been solid, particularly in the infield, where Machado and Kim form one of the best left-side duos in the game. Manager Mike Shildt will likely emphasize aggressive baserunning and double steals in key situations, knowing the Brewers rarely give up extra bases without a fight. If the Padres can capitalize early, take a lead into the seventh, and avoid mental lapses or costly errors, they’ll have a strong chance to steal this one on the road. With the season tightening and every win crucial in a crowded NL postseason picture, San Diego needs to execute cleanly, use its depth wisely, and deliver timely hitting to give their rising rookie and bullpen the run support they need to walk out of Milwaukee with a critical victory.

Credit: USA TODAY/IMAGN
Milwaukee Brewers MLB Preview
The Milwaukee Brewers enter Saturday’s matchup against the San Diego Padres with a 32–28 record and a strong reputation for performing well at home, where they’ve gone 6–4 ATS over their last ten games and 3–1 as moneyline favorites in that span. Veteran right-hander Brandon Woodruff will take the mound for Milwaukee, bringing both experience and consistency as he continues to anchor a rotation that has been one of the National League’s most dependable over the past several seasons. Woodruff enters the contest with a 3–1 record and an ERA just under 3.00, and his ability to locate his fastball up in the zone and use his breaking ball effectively to both sides of the plate has kept hitters off balance, especially in early innings. His presence provides the Brewers with a clear advantage in terms of stability and sets the tone for a pitching staff that relies on high strikeout totals, efficient pitch counts, and minimal walk rates. Offensively, Milwaukee is led by Christian Yelich, who has regained much of his former MVP form with a balanced mix of power, patience, and speed, and William Contreras, one of the league’s most underrated catchers, who continues to be a consistent producer in the middle of the lineup.
Complemented by Willy Adames and Brice Turang, this lineup isn’t known for overwhelming slugging totals but excels in situational hitting and capitalizing on defensive lapses. The Brewers’ offensive game plan often involves extended at-bats, contact-oriented approaches, and aggressive baserunning to apply pressure and force mistakes. Milwaukee’s bullpen remains one of the most important weapons in their arsenal, led by closer Devin Williams and supported by a deep group of setup arms who have thrived in high-leverage innings, limiting opponents’ batting average in the seventh through ninth to one of the league’s lowest. This strength allows manager Pat Murphy to manage games confidently once his starter gets through five or six innings, especially when playing at home where they’ve consistently protected leads. Defensively, the Brewers have been sharp as well, particularly in the infield, where Turang and Adames form a reliable double-play duo and the outfield has avoided costly mistakes with smart positioning and accurate arms. Against a balanced San Diego lineup, the key will be limiting traffic for Soto and Machado, while staying aggressive against the Padres’ younger starter, Stephen Kolek, who will be making just his second road start. If Woodruff can pitch deep into the game and Milwaukee’s offense continues to grind out at-bats and create pressure in the middle innings, the Brewers will be well-positioned to secure a series-defining win. In a matchup that will likely come down to execution and bullpen sharpness, Milwaukee holds the home-field edge and the upper hand in both pitching depth and clutch hitting, giving them a clear path to continue climbing in the NL Central standings.
One of the best rookies in baseball. Period. pic.twitter.com/IDRgqubAxq
— Milwaukee Brewers (@Brewers) June 7, 2025
San Diego vs. Milwaukee Prop Picks (AI)
San Diego vs. Milwaukee Prediction (AI)

Remi, our AI sports wizard, has been pouring over mountains of data from every past game between the Padres and Brewers and using recursive machine learning and industry leading AI to examine the data to a single cover probability.
Remi has been most watching on the unproportionally assigned weight knucklehead sportsbettors often put on coaching factors between a Padres team going up against a possibly strong Brewers team. It appears the true game analytics appear to reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI San Diego vs Milwaukee picks, computer picks Padres vs Brewers, best bets, model edges, confidence ratings.
![]() |
DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 2 |
![]() |
|
MLB | 10/20 | SEA@TOR | UNLOCK THIS PICK | 0 |
![]() |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Padres Betting Trends
San Diego has split run-line decisions evenly over their last ten matchups against the Brewers, going 5–5–0 ATS in head-to-head contests this season.
Brewers Betting Trends
Milwaukee has gone 6–4 ATS in its last 10 home games, including a strong 3–1 mark as favorites, showcasing consistent value for bettors.
Padres vs. Brewers Matchup Trends
The Brewers have won 77.8 percent of their games as moneyline favorites of –149 or shorter, while the Padres have won 55.6 percent as underdogs of +125 or worse—creating a dynamic betting environment.
San Diego vs. Milwaukee Game Info
What time does San Diego vs Milwaukee start on June 07, 2025?
San Diego vs Milwaukee starts on June 07, 2025 at 7:35 PM EST.
Where is San Diego vs Milwaukee being played?
Venue: American Family Field.
What are the opening odds for San Diego vs Milwaukee?
Spread: Milwaukee +1.5
Moneyline: San Diego -104, Milwaukee -115
Over/Under: 8.5
What are the records for San Diego vs Milwaukee?
San Diego: (36-26) | Milwaukee: (34-30)
What is the AI best bet for San Diego vs Milwaukee?
Remi's searched hard and found the best prop for this matchup: J. Chourio over 6.5 Fantasy Score.. Prices move—always shop for the best number.
What are San Diego vs Milwaukee trending bets?
The Brewers have won 77.8 percent of their games as moneyline favorites of –149 or shorter, while the Padres have won 55.6 percent as underdogs of +125 or worse—creating a dynamic betting environment.
What are San Diego trending bets?
SD trend: San Diego has split run-line decisions evenly over their last ten matchups against the Brewers, going 5–5–0 ATS in head-to-head contests this season.
What are Milwaukee trending bets?
MIL trend: Milwaukee has gone 6–4 ATS in its last 10 home games, including a strong 3–1 mark as favorites, showcasing consistent value for bettors.
Where can I find AI Picks for San Diego vs Milwaukee?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
San Diego vs. Milwaukee Odds
Remi is pouring through mountains of data points on each team. In fact, anytime the San Diego vs Milwaukee trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps can often follow normal, predictable betting trends.
San Diego vs Milwaukee Opening Odds
SD Moneyline:
-104 MIL Moneyline: -115
SD Spread: -1.5
MIL Spread: +1.5
Over/Under: 8.5
San Diego vs Milwaukee Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Oct 24, 2025 8:00PM EDT
Los Angeles Dodgers
Toronto Blue Jays
10/24/25 8PM
Dodgers
Blue Jays
|
–
–
|
-154
+130
|
-1.5 (+116)
+1.5 (-140)
|
O 7.5 (+100)
U 7.5 (-122)
|
MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Diego Padres vs. Milwaukee Brewers on June 07, 2025 at American Family Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
![]() |
LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |