Dodgers vs. Guardians
Prediction, Odds & Props
May 28 | MLB AI Picks

Updated: 2025-05-26T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Los Angeles Dodgers and Cleveland Guardians conclude their three-game interleague series on Wednesday, May 28, 2025, at Progressive Field, with first pitch scheduled for 1:10 PM ET. The Dodgers aim to secure a series sweep, while the Guardians look to avoid a home series loss and maintain their position in the competitive AL Central division.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 28, 2025

Start Time: 1:10 PM EST​

Venue: Progressive Field​

Guardians Record: (29-25)

Dodgers Record: (34-21)

OPENING ODDS

LAD Moneyline: -148

CLE Moneyline: +124

LAD Spread: -1.5

CLE Spread: +1.5

Over/Under: 9

LAD
Betting Trends

  • The Dodgers have a 24-22 record against the spread (ATS) this season, reflecting their consistent performance in covering the run line.

CLE
Betting Trends

  • The Guardians have achieved a 27-15 ATS record, showcasing their ability to outperform expectations, particularly at home.

MATCHUP TRENDS

  • The Dodgers have been favored in 44 games this season, winning 63.6% of those matchups, while the Guardians have a 50% win rate in 32 games as underdogs, indicating a competitive edge when not favored.

LAD vs. CLE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: A. Pages over 4.5 Fantasy Score.

LIVE MLB ODDS

MLB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
308-221
VAULT
NET UNITS
(INCL VIG)
+418
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$41,803
EXECUTIVE
VS. SPREAD
1551-1329
EXECUTIVE
NET UNITS
(INCL VIG)
+365.7
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$36,569

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Los Angeles Dodgers vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 5/28/25

The Los Angeles Dodgers and Cleveland Guardians will conclude their interleague series on May 28, 2025, in what promises to be a high-energy midday matchup at Progressive Field, with both clubs entering the contest boasting winning records and postseason aspirations. The Dodgers, leading the NL West with a 33-21 mark, are looking to complete a series sweep while continuing their dominance as one of baseball’s most potent offenses, averaging over 5.5 runs per game and led by the relentless production of Shohei Ohtani and Freddie Freeman. Their ability to string together extra-base hits, draw walks, and execute situational hitting has overwhelmed even quality opponents, and their starting pitching has generally provided enough stability to let the offense take center stage. Veteran lefty Clayton Kershaw has been battling health issues but remains a reliable arm when called upon, and the Dodgers’ bullpen, anchored by Evan Phillips and Brusdar Graterol, has been efficient in late innings. Cleveland, meanwhile, enters the game at 29-24, very much in the thick of the AL Central race, thanks to gritty, contact-first offensive play and a bullpen that has held firm despite injuries to key starters like Shane Bieber. José Ramírez continues to be the Guardians’ offensive engine, leading the team in batting average and RBIs, while Steven Kwan’s consistent top-of-the-order presence has sparked several rallies.

The Guardians have proven they can scrap out close wins, especially at home where they’ve posted a 14-9 record, but containing a deep Dodgers lineup for nine innings is a daunting task—especially given Cleveland’s recent struggle to get quality innings from its rotation. The Dodgers’ aggressive baserunning and lineup flexibility give manager Dave Roberts multiple tools to apply pressure, and with Ohtani’s ability to change a game with one swing or strikeout, they remain a threat in every inning. On the other side, Cleveland’s strategy will depend heavily on limiting the long ball and playing airtight defense, knowing that any lapse could result in a quick scoring burst from L.A. Both clubs are also sharp ATS performers—Cleveland is 27-15 ATS while the Dodgers are 24-22 ATS—indicating that they tend to either outperform expectations or hang tough in competitive games. Cleveland has done well in the underdog role, winning 50% of those games, while the Dodgers have cashed in as favorites in nearly two-thirds of such matchups. This final game is about momentum—whether the Dodgers continue to steamroll toward another dominant stretch or the Guardians claw back and reset their bearings before another AL Central showdown. Look for the Guardians to possibly be more aggressive early to avoid falling behind, but if the Dodgers seize a mid-inning lead, they’ve shown time and again they know how to close. With stars on both sides and postseason implications growing more relevant by the week, this Game 3 finale is set up as a statement opportunity for both franchises.

Los Angeles Dodgers Dodgers MLB Preview

The Los Angeles Dodgers head into the final game of their three-game interleague set against the Cleveland Guardians looking to finish off a road sweep and continue reinforcing their position atop the National League West, riding a potent combination of offensive depth, veteran leadership, and steady pitching that has defined their 2025 campaign thus far. Sitting at 33-21, the Dodgers have delivered consistent performances across all facets of the game, and their approach on the road has been no different—relentless pressure at the plate, sharp defensive play, and a bullpen that holds leads with efficiency. Shohei Ohtani continues to shine as one of the game’s premier two-way threats, showcasing jaw-dropping power numbers and clutch performances both as a designated hitter and occasional starting pitcher, while Freddie Freeman provides the steady veteran bat that anchors the middle of the lineup and sets the tone with professional at-bats. The Dodgers’ supporting cast, including Mookie Betts, Will Smith, and Max Muncy, has supplied timely hits and helped create an offense that can strike from any spot in the order, often overwhelming opposing pitchers through sheer lineup depth. On the mound, while injuries have tested their rotation, Los Angeles has leaned on its depth with younger arms stepping up when needed and veterans like Clayton Kershaw giving quality innings when healthy. The bullpen, led by Evan Phillips and boosted by contributions from Ryan Brasier and Alex Vesia, has remained one of the more reliable late-game units in baseball, limiting opportunities for comebacks.

The Dodgers have also played solid situational baseball, effectively running the bases and managing game flow under manager Dave Roberts, who continues to make the right calls in high-leverage spots. From an ATS perspective, the Dodgers have covered in 24 of 46 games, and have maintained a strong track record when listed as the favorite, winning over 63% of those contests—a reflection of both their betting value and their ability to handle expectations. Heading into a daytime series finale in Cleveland, the Dodgers will look to strike early, knowing that the Guardians’ rotation is vulnerable and that an early lead could quickly break the spirit of a team trying to salvage a game at home. With momentum and talent on their side, Los Angeles will prioritize clean defense, quick innings from their starter, and patient plate appearances that drive up pitch counts and lead to late-inning scoring chances. If they stick to their strengths and avoid the occasional lapses in command that have cost them in tighter games this season, the Dodgers should find themselves in strong position to complete the sweep and carry their winning momentum into the next series. Their blend of experience, star power, and execution under pressure makes them one of the most difficult opponents in baseball, and with a chance to make a statement on the road, expect a focused, all-business approach from a team that has its eyes firmly fixed on October.

The Los Angeles Dodgers and Cleveland Guardians conclude their three-game interleague series on Wednesday, May 28, 2025, at Progressive Field, with first pitch scheduled for 1:10 PM ET. The Dodgers aim to secure a series sweep, while the Guardians look to avoid a home series loss and maintain their position in the competitive AL Central division. Los Angeles Dodgers vs Cleveland AI Prediction: Free MLB Betting Insights for May 28. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Cleveland Guardians MLB Preview

The Cleveland Guardians return to Progressive Field for the finale of a tough interleague series against the Los Angeles Dodgers, aiming to avoid a sweep and reassert their strong early-season form in front of their home crowd. Entering the game at 29-24, the Guardians have been one of the more resilient clubs in the American League, holding their ground in the AL Central despite dealing with a rotation hit hard by injuries, including the long-term absence of ace Shane Bieber. While their starting pitching has been in flux, Cleveland has leaned heavily on a deep and effective bullpen, led by closer Emmanuel Clase, who has remained a reliable force in high-leverage situations and given the Guardians confidence in tight contests. Offensively, José Ramírez continues to be the team’s engine, posting a .311 average with steady run production, while Steven Kwan has thrived in the leadoff spot with his contact-first approach and consistent ability to get on base. Josh Naylor and Andrés Giménez have also contributed in the middle of the order, offering Cleveland enough firepower to stay competitive even when facing elite arms. At home, the Guardians have posted a 14-9 record and covered the spread at an impressive rate, going 27-15 ATS overall this season, which highlights their ability to exceed expectations and grind out games in a fundamentally sound manner.

Despite the challenges of facing one of the league’s most dangerous lineups in the Dodgers, Cleveland’s success often comes from doing the little things well—putting the ball in play, limiting strikeouts, and making routine plays defensively, which allows them to stay in games until their bullpen can take over. For Wednesday’s series finale, the Guardians will likely rely on another bullpen-heavy approach unless a spot starter can provide unexpected length, and their best path to victory will be built on limiting walks, avoiding multi-run innings, and finding ways to manufacture offense against a Dodgers staff that has done well to suppress big innings. Manager Stephen Vogt will need to push the right buttons with matchups and defensive alignments to slow a Los Angeles team that thrives on capitalizing on mistakes and keeping pressure on pitchers from the first pitch. If Cleveland can get early contributions from their core hitters, put a few runners on base ahead of Ramírez, and maintain sharp execution in the field, they’ll have a real shot at salvaging the finale and avoiding the morale dip that a home sweep can trigger. This team has already shown it can rise to the occasion against tough opponents, and with postseason aspirations firmly in play, every game—even in May—has meaningful implications. Expect a scrappy, no-quit effort from a Guardians club that has made its mark this season through heart, depth, and a relentless approach, especially when backed by the energy of a home crowd eager to see their team take down one of MLB’s giants.

Los Angeles Dodgers vs. Cleveland Prop Picks (AI)

Remi is pouring through tons of stats on each line. In fact, anytime the Dodgers and Guardians play there’s always several intriguing angles to key in on. Not to mention games played at Progressive Field in May rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: A. Pages over 4.5 Fantasy Score.

Los Angeles Dodgers vs. Cleveland Prediction (AI)

Remi Robot Icon

Remi, our AI sports genius, has been pouring over millions of data from every facet between the Dodgers and Guardians and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.

Interestingly enough, the data has been most watching on the linear correlation of emphasis knucklehead sportsbettors tend to put on player performance factors between a Dodgers team going up against a possibly unhealthy Guardians team. It appears the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Los Angeles Dodgers vs Cleveland picks, computer picks Dodgers vs Guardians, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Dodgers Betting Trends

The Dodgers have a 24-22 record against the spread (ATS) this season, reflecting their consistent performance in covering the run line.

Guardians Betting Trends

The Guardians have achieved a 27-15 ATS record, showcasing their ability to outperform expectations, particularly at home.

Dodgers vs. Guardians Matchup Trends

The Dodgers have been favored in 44 games this season, winning 63.6% of those matchups, while the Guardians have a 50% win rate in 32 games as underdogs, indicating a competitive edge when not favored.

Los Angeles Dodgers vs. Cleveland Game Info

Los Angeles Dodgers vs Cleveland starts on May 28, 2025 at 1:10 PM EST.

Spread: Cleveland +1.5
Moneyline: Los Angeles Dodgers -148, Cleveland +124
Over/Under: 9

Los Angeles Dodgers: (34-21)  |  Cleveland: (29-25)

Remi's searched hard and found the best prop for this matchup: A. Pages over 4.5 Fantasy Score.. Prices move—always shop for the best number.

The Dodgers have been favored in 44 games this season, winning 63.6% of those matchups, while the Guardians have a 50% win rate in 32 games as underdogs, indicating a competitive edge when not favored.

LAD trend: The Dodgers have a 24-22 record against the spread (ATS) this season, reflecting their consistent performance in covering the run line.

CLE trend: The Guardians have achieved a 27-15 ATS record, showcasing their ability to outperform expectations, particularly at home.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Los Angeles Dodgers vs. Cleveland Odds

AI algorithm Remi is pouring through loads of stats on each team. In fact, anytime the Los Angeles Dodgers vs Cleveland trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps almost always follow normal, predictable betting trends.

Los Angeles Dodgers vs Cleveland Opening Odds

LAD Moneyline: -148
CLE Moneyline: +124
LAD Spread: -1.5
CLE Spread: +1.5
Over/Under: 9

Los Angeles Dodgers vs Cleveland Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-180
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8 (-115)
U 8 (-105)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+125
-150
+1.5 (-180)
-1.5 (+150)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+145
-175
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-195)
-1.5 (+160)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+105
-125
+1.5 (-205)
-1.5 (+170)
O 7.5 (+105)
U 7.5 (-125)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Los Angeles Dodgers Dodgers vs. Cleveland Guardians on May 28, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN