Dodgers vs. Guardians
Prediction, Odds & Props
May 27 | MLB AI Picks

Updated: 2025-05-25T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Los Angeles Dodgers and Cleveland Guardians are set to face off on Tuesday, May 27, 2025, at Progressive Field in Cleveland. The Dodgers, leading the National League West, aim to extend their winning streak, while the Guardians, second in the American League Central, look to bounce back after a recent loss.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 27, 2025

Start Time: 6:10 PM EST​

Venue: Progressive Field​

Guardians Record: (29-24)

Dodgers Record: (33-21)

OPENING ODDS

LAD Moneyline: -136

CLE Moneyline: +115

LAD Spread: -1.5

CLE Spread: +1.5

Over/Under: 8.5

LAD
Betting Trends

  • The Dodgers have a 24-22 record against the spread (ATS) this season.

CLE
Betting Trends

  • The Guardians have a 16-5 record against the spread (ATS) this season.

MATCHUP TRENDS

  • The Dodgers have won 29 of the 45 games they’ve played as favorites this season, translating to a 64.4% win rate.

LAD vs. CLE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: C. Santana over 4.5 Fantasy Score.

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Los Angeles Dodgers vs Cleveland Prediction & Odds:
Free MLB Betting Insights for 5/27/25

The upcoming matchup between the Los Angeles Dodgers and the Cleveland Guardians on Tuesday, May 27, 2025, at Progressive Field is a compelling interleague clash between two playoff-caliber teams looking to solidify their positions atop their respective divisions. The Dodgers, at 32-20, lead the NL West and continue to play like one of the most complete teams in baseball, showcasing elite offensive firepower, solid starting pitching, and a deep bullpen. Their lineup is stacked with stars producing at a high level, including Freddie Freeman who is hitting a scorching .357 with a .636 slugging percentage, Shohei Ohtani who continues to be an all-around force with a .295 average and 13 home runs, and Teoscar Hernández who adds another layer of consistency with a .307 average and 35 RBIs. On the mound, Yoshinobu Yamamoto has quickly asserted himself as a top-tier starter, entering the game with a 5-3 record and an outstanding 1.86 ERA, making him one of the early favorites in the NL Cy Young race. The Dodgers’ ability to combine power hitting with disciplined at-bats and strong pitching makes them a nightmare for any opponent, and their recent momentum puts them in a strong position heading into this road game. However, the Cleveland Guardians have proven to be no pushover, currently sitting at 29-23 and just a game behind the AL Central lead.

Offensively, José Ramírez remains the centerpiece with a .309 average and 11 home runs, while Steven Kwan has quietly been one of the most reliable contact hitters in the league, batting .320 and frequently setting the table for the middle of the lineup. Gavin Williams is expected to start for Cleveland and brings a solid 4-2 record with a 3.94 ERA into the matchup, capable of missing bats and navigating high-leverage innings, but he’ll have to be at his best to contain the Dodgers’ star-studded offense. One key to the game will be which team can execute with runners in scoring position—Cleveland thrives on manufacturing runs and putting pressure on defenses, while the Dodgers often look for the big swing to shift momentum in their favor. Defensively, both teams have been dependable, but the Dodgers’ superior athleticism in the outfield and infield range may give them a slight edge over the course of nine innings. Betting lines suggest a closely matched affair, with Los Angeles favored slightly on the moneyline, and the total runs over/under set at 8.5, reflecting expectations for a moderate scoring contest given the starting pitching. If the Guardians can control the top of the Dodgers’ lineup and Williams gives them a quality start, they’ll have a real shot at defending their home field, especially considering their strong ATS record at home. On the other hand, if Yamamoto continues his dominant stretch and the heart of the L.A. order capitalizes on any mistakes, the Dodgers could find themselves pulling away late. With both teams eyeing momentum as the season approaches the summer grind, this game offers not only quality baseball but also a measuring stick moment for two clubs with legitimate postseason aspirations.

Los Angeles Dodgers Dodgers MLB Preview

The Los Angeles Dodgers enter their Tuesday matchup against the Cleveland Guardians riding the momentum of a 32-20 start to the season and holding firm atop the National League West, powered by a roster that boasts some of the most dangerous offensive talent and dependable pitching in baseball. The Dodgers’ lineup has been nothing short of elite, with first baseman Freddie Freeman leading the way with a phenomenal .357 batting average and a .636 slugging percentage, consistently delivering clutch hits and anchoring the middle of the order. Shohei Ohtani has continued to live up to the massive expectations following his blockbuster arrival in Los Angeles, slashing .295/.638 with 13 home runs and bringing a unique combination of power, speed, and plate discipline that makes him one of the most feared hitters in either league. Teoscar Hernández has emerged as a key piece as well, producing a .307 average with 35 RBIs and providing depth that makes it extremely difficult for opposing pitchers to navigate this lineup unscathed. On the mound, Japanese star Yoshinobu Yamamoto has been outstanding, going 5-3 with a minuscule 1.86 ERA, demonstrating pinpoint control and the ability to go deep into games, something the Dodgers will be counting on against a pesky Guardians offense that thrives on contact and situational hitting. The Dodgers’ bullpen has also been reliable, anchored by closer Evan Phillips and set-up men like Daniel Hudson and Brusdar Graterol, giving manager Dave Roberts confidence in late-inning situations.

Defensively, the Dodgers have been solid across the board, with athleticism and range in both the infield and outfield contributing to their ability to prevent runs and turn potential rallies into quick innings. Strategically, Los Angeles often looks to apply pressure early in games, aiming to get ahead with big innings and force opposing teams to play catch-up, a scenario that favors their deep pitching staff and high-leverage bullpen arms. While their 24-22 record against the spread reflects occasional close finishes or bullpen variability, the overall consistency and high ceiling of this Dodgers squad make them a tough out night after night. Facing Cleveland on the road presents a challenge, particularly given the Guardians’ excellent record at home and their ability to win tight, low-scoring games, but the Dodgers are built for adaptability and thrive in matchups where both power and pitching are decisive factors. If Yamamoto can continue his dominance on the mound and the offense stays true to its patient but aggressive identity, Los Angeles will be well-positioned to secure another victory and extend their lead in the division while reinforcing their status as one of the league’s elite clubs in 2025.

The Los Angeles Dodgers and Cleveland Guardians are set to face off on Tuesday, May 27, 2025, at Progressive Field in Cleveland. The Dodgers, leading the National League West, aim to extend their winning streak, while the Guardians, second in the American League Central, look to bounce back after a recent loss. Los Angeles Dodgers vs Cleveland AI Prediction: Free MLB Betting Insights for May 27. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Cleveland Guardians MLB Preview

The Cleveland Guardians enter Tuesday’s game against the Los Angeles Dodgers with a 29-23 record and second place in the American League Central, looking to continue their strong run at home where they’ve been especially tough to beat. Much of Cleveland’s success this season has come from a well-balanced formula of timely hitting, aggressive base running, and solid pitching, all of which have helped them maintain one of the better records in the American League despite playing in a division that remains highly competitive. Leading the offense is perennial All-Star third baseman José Ramírez, who has been red-hot at the plate with a .309 batting average, .516 slugging percentage, 11 home runs, and 46 RBIs, consistently delivering in clutch situations while providing leadership in the clubhouse and on the field. Leadoff hitter Steven Kwan has also been excellent, batting .320 and reaching base at a high clip, setting the table for Cleveland’s run producers and using his speed to create pressure on opposing pitchers and defenses. The Guardians are expected to give the ball to Gavin Williams, who enters the game with a 4-2 record and a 3.94 ERA across 10 starts, displaying a solid mix of velocity and control, though he’ll face his toughest test yet against one of the most stacked lineups in all of baseball.

Cleveland’s bullpen has been dependable, with Emmanuel Clase anchoring the back end and providing stability in save situations, while Sam Hentges and Hunter Gaddis have been used effectively in setup roles. Defensively, the Guardians are sharp, especially in the infield, where slick glove work from Ramírez, Andrés Giménez, and Gabriel Arias has helped limit extra bases and kept their pitchers confident in putting balls in play. The Guardians’ biggest strength might be their ability to manufacture runs—while they don’t rely on the long ball like some teams, they execute in situational at-bats, move runners efficiently, and are always a threat on the bases thanks to smart, aggressive tactics from manager Stephen Vogt. Against the Dodgers, the Guardians’ path to victory lies in limiting the early damage from L.A.’s powerful bats, particularly Freddie Freeman and Shohei Ohtani, while capitalizing on any scoring opportunities they generate off starter Yoshinobu Yamamoto, who enters with a sparkling 1.86 ERA. The Guardians will look to stretch pitch counts, put balls in play, and force the Dodgers’ defense to make plays, especially in high-leverage moments where a well-placed bunt, stolen base, or sac fly could be the difference. Their 16-5 record against the spread this season underscores how competitive they’ve been in virtually every game, and they’ll need that same level of execution and composure to knock off one of the most complete teams in baseball. A win over the Dodgers not only boosts their position in the division but also sends a message that the Guardians are a legitimate threat as summer approaches and the postseason picture starts to take shape.

Los Angeles Dodgers vs. Cleveland Prop Picks (AI)

Remi is pouring through mountains of datapoints on each line. In fact, anytime the Dodgers and Guardians play there’s always several intriguing trends to key in on. Not to mention games played at Progressive Field in May rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: C. Santana over 4.5 Fantasy Score.

Los Angeles Dodgers vs. Cleveland Prediction (AI)

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Remi, our AI sports genius, has been pouring over tons of data from every facet between the Dodgers and Guardians and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.

The Algorithm has been most keyed in on the unproportionally assigned weight knucklehead sportsbettors often put on Cleveland’s strength factors between a Dodgers team going up against a possibly strong Guardians team. Trends look to say the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Los Angeles Dodgers vs Cleveland picks, computer picks Dodgers vs Guardians, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Dodgers Betting Trends

The Dodgers have a 24-22 record against the spread (ATS) this season.

Guardians Betting Trends

The Guardians have a 16-5 record against the spread (ATS) this season.

Dodgers vs. Guardians Matchup Trends

The Dodgers have won 29 of the 45 games they’ve played as favorites this season, translating to a 64.4% win rate.

Los Angeles Dodgers vs. Cleveland Game Info

Los Angeles Dodgers vs Cleveland starts on May 27, 2025 at 6:10 PM EST.

Spread: Cleveland +1.5
Moneyline: Los Angeles Dodgers -136, Cleveland +115
Over/Under: 8.5

Los Angeles Dodgers: (33-21)  |  Cleveland: (29-24)

Remi's searched hard and found the best prop for this matchup: C. Santana over 4.5 Fantasy Score.. Prices move—always shop for the best number.

The Dodgers have won 29 of the 45 games they’ve played as favorites this season, translating to a 64.4% win rate.

LAD trend: The Dodgers have a 24-22 record against the spread (ATS) this season.

CLE trend: The Guardians have a 16-5 record against the spread (ATS) this season.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Los Angeles Dodgers vs. Cleveland Odds

AI algorithm Remi is pouring through mountains of data on each player. In fact, anytime the Los Angeles Dodgers vs Cleveland trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude seemingly never follow normal, predictable betting trends.

Los Angeles Dodgers vs Cleveland Opening Odds

LAD Moneyline: -136
CLE Moneyline: +115
LAD Spread: -1.5
CLE Spread: +1.5
Over/Under: 8.5

Los Angeles Dodgers vs Cleveland Live Odds

Games PTS ML SPR O/U
In Progress
Baltimore Orioles
New York Yankees
In Progress
Orioles
Yankees
0
6
+2500
-20000
+6.5 (-140)
-6.5 (+110)
O 8.5 (-125)
U 8.5 (-105)
In Progress
St Louis Cardinals
Chicago Cubs
In Progress
Cardinals
Cubs
0
1
 
-300
 
-1.5 (-130)
O 7.5 (-130)
U 7.5 (+100)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+143
-170
+1.5 (-145)
-1.5 (+122)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
Nationals
-110
-110
+1.5 (-210)
-1.5 (+175)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+196
-240
+1.5 (-105)
-1.5 (-115)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-140
+118
-1.5 (+118)
+1.5 (-140)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+100
-120
+1.5 (-205)
-1.5 (+170)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+115
-135
+1.5 (-190)
-1.5 (+158)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+150
-178
+1.5 (-145)
-1.5 (+122)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+126
-150
+1.5 (-190)
-1.5 (+158)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+130
-155
+1.5 (-170)
-1.5 (+143)
O 7.5 (-105)
U 7.5 (-115)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-140
+118
-1.5 (+115)
+1.5 (-135)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
+1.5 (-210)
-1.5 (+175)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
+1.5 (-195)
-1.5 (+162)
O 10 (-115)
U 10 (-105)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Los Angeles Dodgers Dodgers vs. Cleveland Guardians on May 27, 2025 at Progressive Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS