Yankees vs Angels Prediction — AI Finds CAN'T MISS MLB Lines & Props (May 26)
Updated: 2025-05-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
On May 26, 2025, the New York Yankees (29–24) will face the Los Angeles Angels (27–27) at Angel Stadium in Anaheim. Both teams are looking to gain momentum, with the Yankees aiming to strengthen their position in the AL East and the Angels striving to climb the AL West standings.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: May 26, 2025
Start Time: 9:38 PM EST
Venue: Angel Stadium of Anaheim
Angels Record: (25-27)
Yankees Record: (32-20)
OPENING ODDS
NYY Moneyline: -165
LAA Moneyline: +139
NYY Spread: -1.5
LAA Spread: +1.5
Over/Under: 9.5
NYY
Betting Trends
- The Yankees have covered the run line in 3 of their last 11 road games, indicating challenges in meeting betting expectations away from home.
LAA
Betting Trends
- The Angels have a 6–4 record against the spread over their past 10 games, showing consistent performance in covering the run line at home.
MATCHUP TRENDS
- The Yankees have struggled against the spread on the road, while the Angels have been more reliable at home, suggesting a potential edge for the home team in betting terms.
NYY vs. LAA
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: A. Judge over 9.5 Fantasy Score.
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New York Yankees vs Los Angeles Angels Prediction & Odds:
Free MLB Betting Insights for 5/26/25
The offense is capable of erupting, but with a team ERA of 5.04, the Angels have frequently found themselves in slugfests, needing to outscore opponents rather than outpitch them. Their bullpen has struggled to hold leads late in games, making early scoring even more critical. Still, at home they’ve been more effective, covering the run line in six of their last ten and showing better run production when playing in Anaheim. Defensively, the Angels are serviceable, though not elite, and often rely on offensive pressure to mask late-inning vulnerabilities. Betting lines reflect the evenly matched nature of this game, with the Yankees slightly favored but vulnerable on the road, as shown by their 3–8 record against the spread in their last 11 away contests. For New York, the key will be whether Yarbrough can navigate through Trout, Ohtani, and the top of the Angels’ order without surrendering a big inning, while Judge and Rizzo look to continue powering the Yankees’ offense. Conversely, the Angels must maximize their opportunities early and give their bullpen a cushion to work with in the later innings. With both teams fighting to stay above the .500 threshold and maintain momentum in competitive divisions, this matchup promises the blend of star power, urgency, and volatility that could make it one of the day’s most entertaining Memorial Day showdowns.
6th straight series dub. #RepBX pic.twitter.com/FDX8FstdGu
— New York Yankees (@Yankees) May 26, 2025
New York Yankees Yankees MLB Preview
The New York Yankees enter their Memorial Day road matchup against the Los Angeles Angels with a 29–24 record, navigating a season marked by injury setbacks, offensive bursts, and a determined push to remain in the thick of the American League East race. Despite losing Giancarlo Stanton to the injured list and missing ace Gerrit Cole for the season, the Yankees have continued to find ways to win through a blend of veteran leadership, bullpen strength, and explosive offensive output that currently sees them averaging 5.54 runs per game. The driving force of that offense remains Aaron Judge, who continues to deliver as one of the premier power hitters in the game, while Anthony Rizzo provides steady protection behind him with timely hits and solid plate discipline. That duo has kept the Yankees dangerous in the middle innings, while contributions from the supporting cast—like Gleyber Torres and Anthony Volpe—have offered enough balance to make this lineup difficult to navigate for opposing pitchers. The Yankees will turn to Ryan Yarbrough for a spot start in this game, a soft-tossing lefty who relies on deception and location rather than velocity to induce weak contact and extend outings. Yarbrough’s inclusion in the rotation is a reflection of the Yankees’ injury-plagued pitching depth, and his ability to get through the Angels’ potent top half of the lineup—particularly Ohtani and Trout—without allowing early runs will be critical to the game’s tone.
The good news for New York is that their bullpen has been a stabilizing force all year, with multiple arms able to handle leverage situations, shorten games, and protect slim leads. Defensively, the Yankees have executed cleanly, rarely giving away extra bases or making unforced errors, a trend they’ll need to maintain on the road where margins are tighter. However, one glaring issue for the Yankees has been their struggles against the spread when traveling—they’ve covered the run line in just three of their last eleven road games, often playing down to competition or failing to secure blowout wins away from the Bronx. That trend makes this matchup against a .500 Angels team particularly important, as the Yankees look to flip their road narrative and gain momentum on a West Coast trip. Manager Aaron Boone has continued to manage aggressively with substitutions, platoons, and bullpen usage, adjusting to the available roster with a sharp eye on matchups. If the Yankees can strike early with Judge or Rizzo and provide Yarbrough with run support, they’ll be in good shape to let their bullpen take over and lock down a much-needed road win. With the AL East standings as tight as ever, every game holds weight, and this matchup offers the Yankees a prime opportunity to flex their depth and competitive edge against a talented but inconsistent Angels squad. A win here would further solidify New York’s position as a legitimate playoff contender and send a message that even shorthanded, they’re capable of winning anywhere, anytime.

Credit: USA TODAY/IMAGN
Los Angeles Angels Angels MLB Preview
The Los Angeles Angels host the New York Yankees on May 26, 2025, at Angel Stadium with a 27–27 record and the motivation to push themselves above the .500 mark and remain relevant in the AL West playoff race. The Angels have hovered around mediocrity much of the season, but they’ve shown resilience, particularly at home, where they’ve gone 6–4 against the spread in their last 10 games and found more offensive consistency than on the road. At the core of their lineup remains the superstar duo of Mike Trout and Shohei Ohtani, both of whom continue to deliver at a high level—Trout with his hallmark consistency, power, and clutch ability, and Ohtani with his game-breaking power and multi-dimensional impact when healthy. Their combined ability to flip a game with one swing forces pitchers to be cautious and often creates opportunities for players like Taylor Ward and Nolan Schanuel to contribute in run-producing situations. Offensively, the Angels have averaged 4.09 runs per game, a respectable but not elite figure that underscores their need to capitalize on every scoring chance. While the bats have kept them competitive, it’s the pitching—especially the bullpen—that remains the biggest concern. With a team ERA of 5.04, the Angels have struggled to string together quality starts, and late-inning execution has frequently unraveled leads. That vulnerability has made early scoring critical and forced manager Ron Washington to get creative with bullpen roles and matchup strategies.
The rotation has been plagued by inconsistency, and while the Angels have talent, they’ve yet to put it all together for sustained stretches. Defensively, the club has been solid but not spectacular, occasionally faltering in high-leverage moments or when asked to protect narrow leads. Despite these shortcomings, the Angels have been more competitive at home, using familiar conditions and strong crowd energy to play tighter baseball, often forcing opponents into mistakes. Against a banged-up Yankees team missing key stars but still packed with offensive threats, the Angels’ margin for error remains slim, but their recent home performance suggests they could be positioned to take advantage of New York’s road vulnerabilities—particularly if they can get to Ryan Yarbrough early. The Angels’ formula for success will involve jumping on fastballs early in the count, putting pressure on the Yankees’ middle relief arms, and turning to Ohtani and Trout for timely hits in late-game situations. A win here would not only lift the Angels back over .500 but also serve as a morale-boosting benchmark against one of baseball’s most high-profile clubs. For a team that’s battled inconsistency but still harbors postseason ambitions, this is the kind of matchup that could either reignite a playoff push or expose the gaps that still need to be addressed. Either way, the Angels know the stakes and will aim to deliver a complete performance in front of their home crowd on a holiday stage.
FINAL: Marlins 3, Angels 0 pic.twitter.com/d6yC3W2AoM
— Los Angeles Angels (@Angels) May 25, 2025
New York Yankees vs. Los Angeles Angels Prop Picks (AI)
New York Yankees vs. Los Angeles Angels Prediction (AI)

Remi, our AI sports wizard, has been pouring over millions of data from every facet between the Yankees and Angels and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most focused on the growing emphasis emotional bettors often put on player performance factors between a Yankees team going up against a possibly strong Angels team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI New York Yankees vs Los Angeles Angels picks, computer picks Yankees vs Angels, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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Yankees Betting Trends
The Yankees have covered the run line in 3 of their last 11 road games, indicating challenges in meeting betting expectations away from home.
Angels Betting Trends
The Angels have a 6–4 record against the spread over their past 10 games, showing consistent performance in covering the run line at home.
Yankees vs. Angels Matchup Trends
The Yankees have struggled against the spread on the road, while the Angels have been more reliable at home, suggesting a potential edge for the home team in betting terms.
New York Yankees vs. Los Angeles Angels Game Info
What time does New York Yankees vs Los Angeles Angels start on May 26, 2025?
New York Yankees vs Los Angeles Angels starts on May 26, 2025 at 9:38 PM EST.
Where is New York Yankees vs Los Angeles Angels being played?
Venue: Angel Stadium of Anaheim.
What are the opening odds for New York Yankees vs Los Angeles Angels?
Spread: Los Angeles Angels +1.5
Moneyline: New York Yankees -165, Los Angeles Angels +139
Over/Under: 9.5
What are the records for New York Yankees vs Los Angeles Angels?
New York Yankees: (32-20) | Los Angeles Angels: (25-27)
What is the AI best bet for New York Yankees vs Los Angeles Angels?
Remi's searched hard and found the best prop for this matchup: A. Judge over 9.5 Fantasy Score.. Prices move—always shop for the best number.
What are New York Yankees vs Los Angeles Angels trending bets?
The Yankees have struggled against the spread on the road, while the Angels have been more reliable at home, suggesting a potential edge for the home team in betting terms.
What are New York Yankees trending bets?
NYY trend: The Yankees have covered the run line in 3 of their last 11 road games, indicating challenges in meeting betting expectations away from home.
What are Los Angeles Angels trending bets?
LAA trend: The Angels have a 6–4 record against the spread over their past 10 games, showing consistent performance in covering the run line at home.
Where can I find AI Picks for New York Yankees vs Los Angeles Angels?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
New York Yankees vs. Los Angeles Angels Odds
Remi is pouring through loads of data points on each line. In fact, anytime the New York Yankees vs Los Angeles Angels trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable betting trends.
New York Yankees vs Los Angeles Angels Opening Odds
NYY Moneyline:
-165 LAA Moneyline: +139
NYY Spread: -1.5
LAA Spread: +1.5
Over/Under: 9.5
New York Yankees vs Los Angeles Angels Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
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–
–
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+112
-123
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+1.5 (-195)
-1.5 (+171)
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O 7.5 (-114)
U 7.5 (-101)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers New York Yankees Yankees vs. Los Angeles Angels Angels on May 26, 2025 at Angel Stadium of Anaheim.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |