Yankees vs Angels Prediction — AI Finds CAN'T MISS MLB Lines & Props (May 26)

Updated: 2025-05-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On May 26, 2025, the New York Yankees (29–24) will face the Los Angeles Angels (27–27) at Angel Stadium in Anaheim. Both teams are looking to gain momentum, with the Yankees aiming to strengthen their position in the AL East and the Angels striving to climb the AL West standings.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 26, 2025

Start Time: 9:38 PM EST​

Venue: Angel Stadium of Anaheim​

Angels Record: (25-27)

Yankees Record: (32-20)

OPENING ODDS

NYY Moneyline: -165

LAA Moneyline: +139

NYY Spread: -1.5

LAA Spread: +1.5

Over/Under: 9.5

NYY
Betting Trends

  • The Yankees have covered the run line in 3 of their last 11 road games, indicating challenges in meeting betting expectations away from home.

LAA
Betting Trends

  • The Angels have a 6–4 record against the spread over their past 10 games, showing consistent performance in covering the run line at home.

MATCHUP TRENDS

  • The Yankees have struggled against the spread on the road, while the Angels have been more reliable at home, suggesting a potential edge for the home team in betting terms.

NYY vs. LAA
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: A. Judge over 9.5 Fantasy Score.

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New York Yankees vs Los Angeles Angels Prediction & Odds:
Free MLB Betting Insights for 5/26/25

The Memorial Day matchup between the New York Yankees and the Los Angeles Angels at Angel Stadium on May 26, 2025, sets the stage for a compelling cross-division battle between two teams hovering near postseason contention but navigating distinct paths. The Yankees, at 29–24, have been resilient despite being hampered by injuries to key players like Giancarlo Stanton and ace Gerrit Cole, and they continue to compete in a tightly packed AL East. Their offense remains potent, averaging 5.54 runs per game, fueled by the consistent power production of Aaron Judge and the reliability of Anthony Rizzo, whose presence in the heart of the order gives New York a formidable middle lineup. On the mound, Ryan Yarbrough is expected to make a spot start, offering a contrasting style to the typical high-velocity arms and relying instead on pitch movement and location to induce weak contact. The Yankees’ bullpen has picked up the slack admirably, becoming a reliable unit capable of closing out tight games and managing high-leverage innings with confidence. Defensively, the team has remained sharp, limiting errors and supporting the staff with steady glove work, which has become even more important given their fluctuating rotation. Across the diamond, the Angels sit at an even 27–27, reflecting both their offensive firepower and their inconsistencies in run prevention. Shohei Ohtani and Mike Trout continue to be the centerpieces of the Angels’ offense, combining for the bulk of the team’s RBIs and home runs while carrying the weight of expectations every night.

The offense is capable of erupting, but with a team ERA of 5.04, the Angels have frequently found themselves in slugfests, needing to outscore opponents rather than outpitch them. Their bullpen has struggled to hold leads late in games, making early scoring even more critical. Still, at home they’ve been more effective, covering the run line in six of their last ten and showing better run production when playing in Anaheim. Defensively, the Angels are serviceable, though not elite, and often rely on offensive pressure to mask late-inning vulnerabilities. Betting lines reflect the evenly matched nature of this game, with the Yankees slightly favored but vulnerable on the road, as shown by their 3–8 record against the spread in their last 11 away contests. For New York, the key will be whether Yarbrough can navigate through Trout, Ohtani, and the top of the Angels’ order without surrendering a big inning, while Judge and Rizzo look to continue powering the Yankees’ offense. Conversely, the Angels must maximize their opportunities early and give their bullpen a cushion to work with in the later innings. With both teams fighting to stay above the .500 threshold and maintain momentum in competitive divisions, this matchup promises the blend of star power, urgency, and volatility that could make it one of the day’s most entertaining Memorial Day showdowns.

New York Yankees Yankees MLB Preview

The New York Yankees enter their Memorial Day road matchup against the Los Angeles Angels with a 29–24 record, navigating a season marked by injury setbacks, offensive bursts, and a determined push to remain in the thick of the American League East race. Despite losing Giancarlo Stanton to the injured list and missing ace Gerrit Cole for the season, the Yankees have continued to find ways to win through a blend of veteran leadership, bullpen strength, and explosive offensive output that currently sees them averaging 5.54 runs per game. The driving force of that offense remains Aaron Judge, who continues to deliver as one of the premier power hitters in the game, while Anthony Rizzo provides steady protection behind him with timely hits and solid plate discipline. That duo has kept the Yankees dangerous in the middle innings, while contributions from the supporting cast—like Gleyber Torres and Anthony Volpe—have offered enough balance to make this lineup difficult to navigate for opposing pitchers. The Yankees will turn to Ryan Yarbrough for a spot start in this game, a soft-tossing lefty who relies on deception and location rather than velocity to induce weak contact and extend outings. Yarbrough’s inclusion in the rotation is a reflection of the Yankees’ injury-plagued pitching depth, and his ability to get through the Angels’ potent top half of the lineup—particularly Ohtani and Trout—without allowing early runs will be critical to the game’s tone.

The good news for New York is that their bullpen has been a stabilizing force all year, with multiple arms able to handle leverage situations, shorten games, and protect slim leads. Defensively, the Yankees have executed cleanly, rarely giving away extra bases or making unforced errors, a trend they’ll need to maintain on the road where margins are tighter. However, one glaring issue for the Yankees has been their struggles against the spread when traveling—they’ve covered the run line in just three of their last eleven road games, often playing down to competition or failing to secure blowout wins away from the Bronx. That trend makes this matchup against a .500 Angels team particularly important, as the Yankees look to flip their road narrative and gain momentum on a West Coast trip. Manager Aaron Boone has continued to manage aggressively with substitutions, platoons, and bullpen usage, adjusting to the available roster with a sharp eye on matchups. If the Yankees can strike early with Judge or Rizzo and provide Yarbrough with run support, they’ll be in good shape to let their bullpen take over and lock down a much-needed road win. With the AL East standings as tight as ever, every game holds weight, and this matchup offers the Yankees a prime opportunity to flex their depth and competitive edge against a talented but inconsistent Angels squad. A win here would further solidify New York’s position as a legitimate playoff contender and send a message that even shorthanded, they’re capable of winning anywhere, anytime.

On May 26, 2025, the New York Yankees (29–24) will face the Los Angeles Angels (27–27) at Angel Stadium in Anaheim. Both teams are looking to gain momentum, with the Yankees aiming to strengthen their position in the AL East and the Angels striving to climb the AL West standings. New York Yankees vs Los Angeles Angels AI Prediction: Free MLB Betting Insights for May 26. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Los Angeles Angels Angels MLB Preview

The Los Angeles Angels host the New York Yankees on May 26, 2025, at Angel Stadium with a 27–27 record and the motivation to push themselves above the .500 mark and remain relevant in the AL West playoff race. The Angels have hovered around mediocrity much of the season, but they’ve shown resilience, particularly at home, where they’ve gone 6–4 against the spread in their last 10 games and found more offensive consistency than on the road. At the core of their lineup remains the superstar duo of Mike Trout and Shohei Ohtani, both of whom continue to deliver at a high level—Trout with his hallmark consistency, power, and clutch ability, and Ohtani with his game-breaking power and multi-dimensional impact when healthy. Their combined ability to flip a game with one swing forces pitchers to be cautious and often creates opportunities for players like Taylor Ward and Nolan Schanuel to contribute in run-producing situations. Offensively, the Angels have averaged 4.09 runs per game, a respectable but not elite figure that underscores their need to capitalize on every scoring chance. While the bats have kept them competitive, it’s the pitching—especially the bullpen—that remains the biggest concern. With a team ERA of 5.04, the Angels have struggled to string together quality starts, and late-inning execution has frequently unraveled leads. That vulnerability has made early scoring critical and forced manager Ron Washington to get creative with bullpen roles and matchup strategies.

The rotation has been plagued by inconsistency, and while the Angels have talent, they’ve yet to put it all together for sustained stretches. Defensively, the club has been solid but not spectacular, occasionally faltering in high-leverage moments or when asked to protect narrow leads. Despite these shortcomings, the Angels have been more competitive at home, using familiar conditions and strong crowd energy to play tighter baseball, often forcing opponents into mistakes. Against a banged-up Yankees team missing key stars but still packed with offensive threats, the Angels’ margin for error remains slim, but their recent home performance suggests they could be positioned to take advantage of New York’s road vulnerabilities—particularly if they can get to Ryan Yarbrough early. The Angels’ formula for success will involve jumping on fastballs early in the count, putting pressure on the Yankees’ middle relief arms, and turning to Ohtani and Trout for timely hits in late-game situations. A win here would not only lift the Angels back over .500 but also serve as a morale-boosting benchmark against one of baseball’s most high-profile clubs. For a team that’s battled inconsistency but still harbors postseason ambitions, this is the kind of matchup that could either reignite a playoff push or expose the gaps that still need to be addressed. Either way, the Angels know the stakes and will aim to deliver a complete performance in front of their home crowd on a holiday stage.

New York Yankees vs. Los Angeles Angels Prop Picks (AI)

Remi is pouring through mountains of data on each line. In fact, anytime the Yankees and Angels play there’s always several intriguing trends to key in on. Not to mention games played at Angel Stadium of Anaheim in May almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: A. Judge over 9.5 Fantasy Score.

New York Yankees vs. Los Angeles Angels Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every facet between the Yankees and Angels and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.

Interestingly enough, the data has been most focused on the growing emphasis emotional bettors often put on player performance factors between a Yankees team going up against a possibly strong Angels team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line specifically.

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Below is our current AI New York Yankees vs Los Angeles Angels picks, computer picks Yankees vs Angels, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Yankees Betting Trends

The Yankees have covered the run line in 3 of their last 11 road games, indicating challenges in meeting betting expectations away from home.

Angels Betting Trends

The Angels have a 6–4 record against the spread over their past 10 games, showing consistent performance in covering the run line at home.

Yankees vs. Angels Matchup Trends

The Yankees have struggled against the spread on the road, while the Angels have been more reliable at home, suggesting a potential edge for the home team in betting terms.

New York Yankees vs. Los Angeles Angels Game Info

New York Yankees vs Los Angeles Angels starts on May 26, 2025 at 9:38 PM EST.

Spread: Los Angeles Angels +1.5
Moneyline: New York Yankees -165, Los Angeles Angels +139
Over/Under: 9.5

New York Yankees: (32-20)  |  Los Angeles Angels: (25-27)

Remi's searched hard and found the best prop for this matchup: A. Judge over 9.5 Fantasy Score.. Prices move—always shop for the best number.

The Yankees have struggled against the spread on the road, while the Angels have been more reliable at home, suggesting a potential edge for the home team in betting terms.

NYY trend: The Yankees have covered the run line in 3 of their last 11 road games, indicating challenges in meeting betting expectations away from home.

LAA trend: The Angels have a 6–4 record against the spread over their past 10 games, showing consistent performance in covering the run line at home.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

New York Yankees vs. Los Angeles Angels Odds

Remi is pouring through loads of data points on each line. In fact, anytime the New York Yankees vs Los Angeles Angels trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable betting trends.

New York Yankees vs Los Angeles Angels Opening Odds

NYY Moneyline: -165
LAA Moneyline: +139
NYY Spread: -1.5
LAA Spread: +1.5
Over/Under: 9.5

New York Yankees vs Los Angeles Angels Live Odds

Games PTS ML SPR O/U
Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
+112
-123
+1.5 (-195)
-1.5 (+171)
O 7.5 (-114)
U 7.5 (-101)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Yankees Yankees vs. Los Angeles Angels Angels on May 26, 2025 at Angel Stadium of Anaheim.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TOR@SEA OVER 7 54.9% 3 WIN
LAD@MIL UNDER 7.5 56.6% 6 WIN
TOR@NYY OVER 8 54.9% 4 WIN
TOR@NYY CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED 53.3% 3 WIN
NYY@TOR OVER 7.5 54.8% 2 WIN
LAD@PHI OVER 7 53.8% 3 WIN
SD@CHC CHC -109 53.8% 3 WIN
SD@CHC OVER 7.5 54.5% 4 LOSS
SD@CHC CHC -111 54.8% 4 LOSS
CIN@LAD SHOHEI OHTANI OVER 1.5 BASES 53.5% 3 WIN
BOS@NYY OVER 7 53.8% 3 LOSS
CIN@LAD ELLY DE LA CRUZ OVER 0.5 BASES 54.4% 4 LOSS
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN