Rockies vs Cubs Prediction — AI Finds CAN'T MISS MLB Lines & Props (May 26)

Updated: 2025-05-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Chicago Cubs (30–20) host the Colorado Rockies (8–42) on May 26, 2025, at Wrigley Field in a Memorial Day matchup. The Cubs, leading the NL Central, aim to capitalize on the struggling Rockies, who are enduring one of the worst starts in MLB history.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 26, 2025

Start Time: 2:20 PM EST​

Venue: Wrigley Field​

Cubs Record: (32-21)

Rockies Record: (9-44)

OPENING ODDS

COL Moneyline: +275

CHC Moneyline: -347

COL Spread: +1.5

CHC Spread: -1.5

Over/Under: 8

COL
Betting Trends

  • The Rockies have hit the team total under in 28 of their last 44 games, indicating a consistent trend of underperforming offensively.

CHC
Betting Trends

  • The Cubs have a 31–18 record against the spread (ATS), showcasing their strong performance in covering the run line this season.

MATCHUP TRENDS

  • The Rockies’ team total under trend suggests a continued struggle to generate runs, while the Cubs’ strong ATS record highlights their ability to cover spreads, especially against weaker opponents.

COL vs. CHC
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Taillon under 32.5 Fantasy Score.

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Colorado vs Chicago Cubs Prediction & Odds:
Free MLB Betting Insights for 5/26/25

The May 26, 2025 matchup between the Colorado Rockies and Chicago Cubs at Wrigley Field presents one of the most lopsided games on the MLB calendar, pitting a first-place team in the Cubs against a Colorado squad enduring one of the worst starts in league history. Entering the contest with a 30–20 record, the Cubs sit atop the NL Central and have impressed with their potent offense, reliable pitching, and consistently strong performances at home. Averaging 6.00 runs and 9.18 hits per game, Chicago boasts one of the league’s most dynamic lineups, led by breakout star Pete Crow-Armstrong, who is hitting .286 with an .891 OPS. Their balanced attack has helped them cover the run line in 31 of 49 games, and they enter this matchup with the clear expectation of extending their winning ways against a reeling Rockies team. Colorado, by contrast, enters Wrigley Field with a historically poor 8–42 record, plagued by weak starting pitching, minimal run production, and subpar defensive execution. The Rockies have struggled to reach their team run totals in 28 of their last 44 games, and their starter for Monday, Carson Palmquist, has been one of the worst in the league statistically, posting an 11.88 ERA and a 2.52 WHIP—figures that suggest trouble keeping the Cubs’ offense in check.

Offensively, Colorado has failed to support its pitching staff, ranking near the bottom of the majors in runs scored and batting average, and often failing to string together enough quality at-bats to compete. Defensively, the Rockies have compounded their problems with poor fielding metrics, leading the league in errors and lacking range across the infield and outfield. Chicago’s pitching, anchored by a 4.24 team ERA, should have little difficulty containing a Rockies lineup that rarely capitalizes on scoring chances. The Cubs also benefit from a bullpen that has done well in late-game situations, allowing manager Craig Counsell to manage leads effectively. If the Cubs jump out early, which is likely against Palmquist, the game could quickly spiral out of reach for Colorado, who have shown little fight in blowout losses this season. This contest is less about whether Chicago will win and more about how decisively they’ll do so, as bettors and fans alike expect a dominant performance from a team that has not only played well but done so with confidence and consistency. Chicago will look to use this game as a stepping stone to build further momentum and tighten their grip on the division lead, while Colorado is simply hoping to avoid another demoralizing defeat. With the Cubs surging and the Rockies sliding into deeper irrelevance, Monday’s matchup has all the makings of a blowout and will likely reinforce the vast gulf between these two teams in nearly every measurable category.

Colorado Rockies MLB Preview

The Colorado Rockies enter their Memorial Day road matchup against the Chicago Cubs with the worst record in Major League Baseball at 8–42, marking one of the most disastrous starts to a season in recent memory. The Rockies are mired in a tailspin on nearly every level of play—offense, defense, and especially pitching—contributing to their inability to stay competitive in most games. Their upcoming starter, left-hander Carson Palmquist, has epitomized the team’s pitching struggles with an 11.88 ERA and 2.52 WHIP, surrendering runs in bunches and failing to escape early innings in several outings. The team’s bullpen has offered no reprieve, regularly entering games in high-leverage situations only to allow leads to balloon further, compounding the pressure on a batting order that has not delivered. Offensively, Colorado ranks near the bottom of every major statistical category, including runs scored, slugging percentage, and team batting average, and they’ve consistently failed to hit their team total—going under in 28 of their last 44 games. With few bright spots in the lineup, the burden of production has fallen on young and underdeveloped bats, most of whom are struggling against high-level pitching. The Rockies’ inability to get on base and capitalize on scoring opportunities has rendered even average pitching matchups difficult, and facing a red-hot Cubs team in Wrigley Field only compounds those difficulties.

Defensively, the Rockies have been equally ineffective, ranking last in defensive efficiency and plagued by costly errors and poor infield communication that regularly turns routine plays into run-scoring opportunities for opponents. Their fielding has placed additional strain on an already overmatched pitching staff, and the combination of poor glove work and ineffective arms has left the team chasing games from the outset. In terms of management, the team has cycled through lineups, bullpen roles, and even coaching philosophies, but nothing has yielded a sustainable solution to their woes. Monday’s contest presents a near-impossible challenge: stopping a Cubs lineup that averages six runs per game while trying to cobble together enough offense to support a pitcher with one of the highest ERAs in the league. Even minor victories—avoiding double-digit losses, getting through five innings without a meltdown, or keeping the game within a few runs—are likely considered progress for this group at this point. As the Rockies continue to search for signs of development in a season that already feels lost, games like these are more about evaluating talent and instilling a culture of resilience than making a serious push for wins. Unfortunately, against a confident and surging Cubs team, Colorado looks completely outmatched, and unless they can summon a rare offensive surge or hope for a collapse on the other side, they appear poised to suffer another defeat in a season where those have become painfully routine.

The Chicago Cubs (30–20) host the Colorado Rockies (8–42) on May 26, 2025, at Wrigley Field in a Memorial Day matchup. The Cubs, leading the NL Central, aim to capitalize on the struggling Rockies, who are enduring one of the worst starts in MLB history. Colorado vs Chicago Cubs AI Prediction: Free MLB Betting Insights for May 26. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Chicago Cubs Cubs MLB Preview

The Chicago Cubs return to Wrigley Field on May 26, 2025, holding a commanding 30–20 record and leading the National League Central, poised to take advantage of a matchup against the MLB-worst Colorado Rockies. With one of the most well-rounded rosters in the league, the Cubs have struck a balance between offensive consistency, competent pitching, and sharp defensive execution, making them one of the more reliable teams both on the field and against the spread, where they’ve covered in 31 of 49 contests. Offensively, the Cubs have flourished, averaging 6.00 runs per game and 9.18 hits, powered by breakout star Pete Crow-Armstrong, who enters the game hitting .286 with an .891 OPS. His mix of power, speed, and contact hitting has added another layer to a lineup that wears down pitchers by grinding at-bats and applying pressure from top to bottom. Surrounding him are dependable contributors like Nico Hoerner and Christopher Morel, who have each added timely hits and defensive versatility. From a pitching standpoint, the Cubs have held steady with a team ERA of 4.24, more than good enough when combined with their potent offense. The bullpen has been especially valuable in late-game situations, routinely shutting down rallies and preserving leads thanks to consistent roles and strong command. Manager Craig Counsell has shown a steady hand in managing both the lineup and bullpen, using matchups and splits to keep the Cubs one step ahead tactically.

Defensively, Chicago has been one of the sharper clubs in the majors, with infield and outfield units that rarely make errors and regularly convert difficult plays into outs. Against a Colorado Rockies team that has stumbled to an 8–42 start with massive issues in starting pitching, bullpen depth, and offensive production, the Cubs should be expected to attack early and put the game out of reach before the Rockies can find any rhythm. With Carson Palmquist starting for Colorado, bringing a bloated 11.88 ERA and 2.52 WHIP, the Cubs’ lineup will look to pounce in the early innings, likely targeting fastballs up in the zone and driving the ball to the gaps. The key for Chicago will be to avoid complacency, maintain the same aggressive but patient approach at the plate that has brought them success, and not allow Colorado’s struggles to lead to sloppy play. In games like these, where the margin for error is wide and expectations are high, maintaining discipline and executing the fundamentals will be what separates a solid win from a dominant one. The Cubs are well-positioned to continue their winning streak, keep pressure on the rest of the division, and take advantage of a rare opportunity to secure an emphatic victory against a struggling opponent at home, where the Wrigley faithful will be expecting a performance that reflects the vast difference between these two clubs.

Colorado vs. Chicago Cubs Prop Picks (AI)

Remi is pouring through tons of stats on each team. In fact, anytime the Rockies and Cubs play there’s always several intriguing observations to key in on. Not to mention games played at Wrigley Field in May rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: J. Taillon under 32.5 Fantasy Score.

Colorado vs. Chicago Cubs Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every past game between the Rockies and Cubs and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.

Interestingly enough, the data has been most fixated on the unproportionally assigned emphasis human bettors regularly put on Colorado’s strength factors between a Rockies team going up against a possibly deflated Cubs team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line specifically.

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Below is our current AI Colorado vs Chicago Cubs picks, computer picks Rockies vs Cubs, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Rockies Betting Trends

The Rockies have hit the team total under in 28 of their last 44 games, indicating a consistent trend of underperforming offensively.

Cubs Betting Trends

The Cubs have a 31–18 record against the spread (ATS), showcasing their strong performance in covering the run line this season.

Rockies vs. Cubs Matchup Trends

The Rockies’ team total under trend suggests a continued struggle to generate runs, while the Cubs’ strong ATS record highlights their ability to cover spreads, especially against weaker opponents.

Colorado vs. Chicago Cubs Game Info

Colorado vs Chicago Cubs starts on May 26, 2025 at 2:20 PM EST.

Spread: Chicago Cubs -1.5
Moneyline: Colorado +275, Chicago Cubs -347
Over/Under: 8

Colorado: (9-44)  |  Chicago Cubs: (32-21)

Remi's searched hard and found the best prop for this matchup: J. Taillon under 32.5 Fantasy Score.. Prices move—always shop for the best number.

The Rockies’ team total under trend suggests a continued struggle to generate runs, while the Cubs’ strong ATS record highlights their ability to cover spreads, especially against weaker opponents.

COL trend: The Rockies have hit the team total under in 28 of their last 44 games, indicating a consistent trend of underperforming offensively.

CHC trend: The Cubs have a 31–18 record against the spread (ATS), showcasing their strong performance in covering the run line this season.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Colorado vs. Chicago Cubs Odds

AI algorithm Remi is pouring through mountains of data on each line. In fact, anytime the Colorado vs Chicago Cubs trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps almost always follow normal, predictable patterns.

Colorado vs Chicago Cubs Opening Odds

COL Moneyline: +275
CHC Moneyline: -347
COL Spread: +1.5
CHC Spread: -1.5
Over/Under: 8

Colorado vs Chicago Cubs Live Odds

Games PTS ML SPR O/U
Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
+110
-130
+1.5 (-205)
-1.5 (+170)
O 7.5 (-115)
U 7.5 (-105)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Colorado Rockies vs. Chicago Cubs Cubs on May 26, 2025 at Wrigley Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
TOR@SEA OVER 7 54.9% 3 WIN
LAD@MIL UNDER 7.5 56.6% 6 WIN
TOR@NYY OVER 8 54.9% 4 WIN
TOR@NYY CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED 53.3% 3 WIN
NYY@TOR OVER 7.5 54.8% 2 WIN
LAD@PHI OVER 7 53.8% 3 WIN
SD@CHC CHC -109 53.8% 3 WIN
SD@CHC OVER 7.5 54.5% 4 LOSS
SD@CHC CHC -111 54.8% 4 LOSS
CIN@LAD SHOHEI OHTANI OVER 1.5 BASES 53.5% 3 WIN
BOS@NYY OVER 7 53.8% 3 LOSS
CIN@LAD ELLY DE LA CRUZ OVER 0.5 BASES 54.4% 4 LOSS
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN