Rockies vs Cubs Prediction — AI Finds CAN'T MISS MLB Lines & Props (May 26)
Updated: 2025-05-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Chicago Cubs (30–20) host the Colorado Rockies (8–42) on May 26, 2025, at Wrigley Field in a Memorial Day matchup. The Cubs, leading the NL Central, aim to capitalize on the struggling Rockies, who are enduring one of the worst starts in MLB history.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: May 26, 2025
Start Time: 2:20 PM EST
Venue: Wrigley Field
Cubs Record: (32-21)
Rockies Record: (9-44)
OPENING ODDS
COL Moneyline: +275
CHC Moneyline: -347
COL Spread: +1.5
CHC Spread: -1.5
Over/Under: 8
COL
Betting Trends
- The Rockies have hit the team total under in 28 of their last 44 games, indicating a consistent trend of underperforming offensively.
CHC
Betting Trends
- The Cubs have a 31–18 record against the spread (ATS), showcasing their strong performance in covering the run line this season.
MATCHUP TRENDS
- The Rockies’ team total under trend suggests a continued struggle to generate runs, while the Cubs’ strong ATS record highlights their ability to cover spreads, especially against weaker opponents.
COL vs. CHC
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: J. Taillon under 32.5 Fantasy Score.
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Colorado vs Chicago Cubs Prediction & Odds:
Free MLB Betting Insights for 5/26/25
Offensively, Colorado has failed to support its pitching staff, ranking near the bottom of the majors in runs scored and batting average, and often failing to string together enough quality at-bats to compete. Defensively, the Rockies have compounded their problems with poor fielding metrics, leading the league in errors and lacking range across the infield and outfield. Chicago’s pitching, anchored by a 4.24 team ERA, should have little difficulty containing a Rockies lineup that rarely capitalizes on scoring chances. The Cubs also benefit from a bullpen that has done well in late-game situations, allowing manager Craig Counsell to manage leads effectively. If the Cubs jump out early, which is likely against Palmquist, the game could quickly spiral out of reach for Colorado, who have shown little fight in blowout losses this season. This contest is less about whether Chicago will win and more about how decisively they’ll do so, as bettors and fans alike expect a dominant performance from a team that has not only played well but done so with confidence and consistency. Chicago will look to use this game as a stepping stone to build further momentum and tighten their grip on the division lead, while Colorado is simply hoping to avoid another demoralizing defeat. With the Cubs surging and the Rockies sliding into deeper irrelevance, Monday’s matchup has all the makings of a blowout and will likely reinforce the vast gulf between these two teams in nearly every measurable category.
HEY MICKEY! pic.twitter.com/ahOYEOMrFe
— Colorado Rockies (@Rockies) May 25, 2025
Colorado Rockies MLB Preview
The Colorado Rockies enter their Memorial Day road matchup against the Chicago Cubs with the worst record in Major League Baseball at 8–42, marking one of the most disastrous starts to a season in recent memory. The Rockies are mired in a tailspin on nearly every level of play—offense, defense, and especially pitching—contributing to their inability to stay competitive in most games. Their upcoming starter, left-hander Carson Palmquist, has epitomized the team’s pitching struggles with an 11.88 ERA and 2.52 WHIP, surrendering runs in bunches and failing to escape early innings in several outings. The team’s bullpen has offered no reprieve, regularly entering games in high-leverage situations only to allow leads to balloon further, compounding the pressure on a batting order that has not delivered. Offensively, Colorado ranks near the bottom of every major statistical category, including runs scored, slugging percentage, and team batting average, and they’ve consistently failed to hit their team total—going under in 28 of their last 44 games. With few bright spots in the lineup, the burden of production has fallen on young and underdeveloped bats, most of whom are struggling against high-level pitching. The Rockies’ inability to get on base and capitalize on scoring opportunities has rendered even average pitching matchups difficult, and facing a red-hot Cubs team in Wrigley Field only compounds those difficulties.
Defensively, the Rockies have been equally ineffective, ranking last in defensive efficiency and plagued by costly errors and poor infield communication that regularly turns routine plays into run-scoring opportunities for opponents. Their fielding has placed additional strain on an already overmatched pitching staff, and the combination of poor glove work and ineffective arms has left the team chasing games from the outset. In terms of management, the team has cycled through lineups, bullpen roles, and even coaching philosophies, but nothing has yielded a sustainable solution to their woes. Monday’s contest presents a near-impossible challenge: stopping a Cubs lineup that averages six runs per game while trying to cobble together enough offense to support a pitcher with one of the highest ERAs in the league. Even minor victories—avoiding double-digit losses, getting through five innings without a meltdown, or keeping the game within a few runs—are likely considered progress for this group at this point. As the Rockies continue to search for signs of development in a season that already feels lost, games like these are more about evaluating talent and instilling a culture of resilience than making a serious push for wins. Unfortunately, against a confident and surging Cubs team, Colorado looks completely outmatched, and unless they can summon a rare offensive surge or hope for a collapse on the other side, they appear poised to suffer another defeat in a season where those have become painfully routine.

Credit: USA TODAY/IMAGN
Chicago Cubs Cubs MLB Preview
The Chicago Cubs return to Wrigley Field on May 26, 2025, holding a commanding 30–20 record and leading the National League Central, poised to take advantage of a matchup against the MLB-worst Colorado Rockies. With one of the most well-rounded rosters in the league, the Cubs have struck a balance between offensive consistency, competent pitching, and sharp defensive execution, making them one of the more reliable teams both on the field and against the spread, where they’ve covered in 31 of 49 contests. Offensively, the Cubs have flourished, averaging 6.00 runs per game and 9.18 hits, powered by breakout star Pete Crow-Armstrong, who enters the game hitting .286 with an .891 OPS. His mix of power, speed, and contact hitting has added another layer to a lineup that wears down pitchers by grinding at-bats and applying pressure from top to bottom. Surrounding him are dependable contributors like Nico Hoerner and Christopher Morel, who have each added timely hits and defensive versatility. From a pitching standpoint, the Cubs have held steady with a team ERA of 4.24, more than good enough when combined with their potent offense. The bullpen has been especially valuable in late-game situations, routinely shutting down rallies and preserving leads thanks to consistent roles and strong command. Manager Craig Counsell has shown a steady hand in managing both the lineup and bullpen, using matchups and splits to keep the Cubs one step ahead tactically.
Defensively, Chicago has been one of the sharper clubs in the majors, with infield and outfield units that rarely make errors and regularly convert difficult plays into outs. Against a Colorado Rockies team that has stumbled to an 8–42 start with massive issues in starting pitching, bullpen depth, and offensive production, the Cubs should be expected to attack early and put the game out of reach before the Rockies can find any rhythm. With Carson Palmquist starting for Colorado, bringing a bloated 11.88 ERA and 2.52 WHIP, the Cubs’ lineup will look to pounce in the early innings, likely targeting fastballs up in the zone and driving the ball to the gaps. The key for Chicago will be to avoid complacency, maintain the same aggressive but patient approach at the plate that has brought them success, and not allow Colorado’s struggles to lead to sloppy play. In games like these, where the margin for error is wide and expectations are high, maintaining discipline and executing the fundamentals will be what separates a solid win from a dominant one. The Cubs are well-positioned to continue their winning streak, keep pressure on the rest of the division, and take advantage of a rare opportunity to secure an emphatic victory against a struggling opponent at home, where the Wrigley faithful will be expecting a performance that reflects the vast difference between these two clubs.
GONNEEEEE
— Chicago Cubs (@Cubs) May 25, 2025
SEIYA. SUZUKI. pic.twitter.com/pLFOOpGXe3
Colorado vs. Chicago Cubs Prop Picks (AI)
Colorado vs. Chicago Cubs Prediction (AI)

Remi, our AI sports genius, has been pouring over millions of data from every past game between the Rockies and Cubs and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most fixated on the unproportionally assigned emphasis human bettors regularly put on Colorado’s strength factors between a Rockies team going up against a possibly deflated Cubs team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Colorado vs Chicago Cubs picks, computer picks Rockies vs Cubs, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Rockies Betting Trends
The Rockies have hit the team total under in 28 of their last 44 games, indicating a consistent trend of underperforming offensively.
Cubs Betting Trends
The Cubs have a 31–18 record against the spread (ATS), showcasing their strong performance in covering the run line this season.
Rockies vs. Cubs Matchup Trends
The Rockies’ team total under trend suggests a continued struggle to generate runs, while the Cubs’ strong ATS record highlights their ability to cover spreads, especially against weaker opponents.
Colorado vs. Chicago Cubs Game Info
What time does Colorado vs Chicago Cubs start on May 26, 2025?
Colorado vs Chicago Cubs starts on May 26, 2025 at 2:20 PM EST.
Where is Colorado vs Chicago Cubs being played?
Venue: Wrigley Field.
What are the opening odds for Colorado vs Chicago Cubs?
Spread: Chicago Cubs -1.5
Moneyline: Colorado +275, Chicago Cubs -347
Over/Under: 8
What are the records for Colorado vs Chicago Cubs?
Colorado: (9-44) | Chicago Cubs: (32-21)
What is the AI best bet for Colorado vs Chicago Cubs?
Remi's searched hard and found the best prop for this matchup: J. Taillon under 32.5 Fantasy Score.. Prices move—always shop for the best number.
What are Colorado vs Chicago Cubs trending bets?
The Rockies’ team total under trend suggests a continued struggle to generate runs, while the Cubs’ strong ATS record highlights their ability to cover spreads, especially against weaker opponents.
What are Colorado trending bets?
COL trend: The Rockies have hit the team total under in 28 of their last 44 games, indicating a consistent trend of underperforming offensively.
What are Chicago Cubs trending bets?
CHC trend: The Cubs have a 31–18 record against the spread (ATS), showcasing their strong performance in covering the run line this season.
Where can I find AI Picks for Colorado vs Chicago Cubs?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Colorado vs. Chicago Cubs Odds
AI algorithm Remi is pouring through mountains of data on each line. In fact, anytime the Colorado vs Chicago Cubs trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps almost always follow normal, predictable patterns.
Colorado vs Chicago Cubs Opening Odds
COL Moneyline:
+275 CHC Moneyline: -347
COL Spread: +1.5
CHC Spread: -1.5
Over/Under: 8
Colorado vs Chicago Cubs Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
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–
–
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+110
-130
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+1.5 (-205)
-1.5 (+170)
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O 7.5 (-115)
U 7.5 (-105)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Colorado Rockies vs. Chicago Cubs Cubs on May 26, 2025 at Wrigley Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |