Brewers vs. Pirates
Prediction, Odds & Props
May 23 | MLB AI Picks

Updated: 2025-05-21T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On May 23, 2025, the Milwaukee Brewers will face the Pittsburgh Pirates at PNC Park in Pittsburgh, Pennsylvania. This National League Central matchup features two teams aiming to improve their standings in the division.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 23, 2025

Start Time: 6:40 PM EST​

Venue: PNC Park​

Pirates Record: (17-34)

Brewers Record: (25-26)

OPENING ODDS

MIL Moneyline: +105

PIT Moneyline: -125

MIL Spread: -1.5

PIT Spread: +1.5

Over/Under: 7

MIL
Betting Trends

  • The Milwaukee Brewers have a 3–7 record against the run line in their last 10 games.

PIT
Betting Trends

  • The Pittsburgh Pirates have a 4–6 record against the run line in their last 10 home games.

MATCHUP TRENDS

  • The Brewers have a 24–26 record against the run line this season, covering 48% of the time. The Pirates have a 15–32 record against the run line this season, covering 31.9% of the time.

MIL vs. PIT
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: F. Peralta over 22.5 Fantasy Score.

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Milwaukee vs Pittsburgh Prediction & Odds:
Free MLB Betting Insights for 5/23/25

The May 23, 2025 matchup between the Milwaukee Brewers and Pittsburgh Pirates at PNC Park represents a critical opportunity for both clubs to stabilize their seasons and begin making up ground in a highly competitive National League Central. The Brewers, currently sitting at 24–26, have hit a rough patch after a decent start, going just 3–7 over their last 10 games and seeing their offensive and pitching production trend in the wrong direction. The inconsistency at the plate has been particularly problematic, as the team has struggled to sustain rallies or produce with runners in scoring position, leading to close losses and missed opportunities to gain traction in the division. On the mound, Milwaukee’s once-reliable pitching staff has been shaky, unable to hold slim leads and placing additional stress on the bullpen, which has logged too many innings during this skid. Meanwhile, the Pirates come into this game with a 15–32 record and a season that has been defined by frequent struggles, especially with run prevention and offensive firepower. Pittsburgh has shown small signs of life recently, going 4–6 in their last 10 home games, but remains mired in last place and unable to put together sustained momentum, in large part due to a young and inconsistent roster that lacks both the depth and experience to compete night in and night out against higher-tier teams.

Their pitching has been a consistent weakness, ranking among the league’s worst in ERA, while the offense, despite occasional bursts, has been largely reliant on a few standout players who haven’t been enough to carry the load. From a betting standpoint, the Brewers are 3–7 against the run line in their last 10 and 24–26 overall, while the Pirates are a troubling 15–32 ATS this season—covering just under 32% of the time—which is a reflection of their inability to keep games close even when not favored. The Brewers’ road performance has also been underwhelming, with a 9–16 record away from American Family Field, meaning this game has the potential to be a struggle for both sides if neither team finds a rhythm early. Both managers will be looking to set the tone early—Milwaukee by leaning on quality starting pitching and patient, timely hitting, and Pittsburgh by hoping to exploit the Brewers’ recent vulnerabilities and generate offense early to lift the confidence of a team desperate for a win. In what could be a low-scoring, grind-it-out affair, the key will be who can limit defensive mistakes, get quality innings from their starter, and capitalize on the few scoring chances that arise. The Brewers, with slightly better depth and playoff aspirations, have more pressure to win this game and should be considered slight favorites, but the Pirates have shown they’re capable of playing spoiler—especially at home—if they can get solid pitching and a timely big hit. This game may not have major postseason implications today, but for two teams teetering on the edge of their respective goals, it carries plenty of urgency.

Milwaukee Brewers MLB Preview

The Milwaukee Brewers come into their May 23 matchup against the Pittsburgh Pirates desperate to reverse a recent skid that has seen them drop seven of their last 10 games, sliding to 24–26 on the season and slowly losing ground in the National League Central standings as their once-solid formula of strong pitching and opportunistic hitting has begun to falter. After a promising start to 2025, the Brewers are now struggling on both sides of the ball, particularly on the road, where they’ve posted a 9–16 record and have repeatedly failed to capitalize on scoring chances while their bullpen has shown signs of fatigue from being overworked due to short starts from the rotation. Offensively, Milwaukee has not found a consistent rhythm, with several key bats slumping and the lineup failing to string together productive innings, often relying on solo home runs or late-inning rallies that have fallen short more often than not. In recent games, the team has battled through injuries and roster adjustments, but their depth has been tested, and the lack of production from the bottom half of the order has been glaring in tight contests where every base runner matters.

The pitching staff, typically a strength for the Brewers, has also underperformed, with starters struggling to work deep into games and the bullpen being leaned on too heavily, leading to diminished results in high-leverage situations. Despite posting a 24–26 record against the run line this season and showing some resilience in games they win, Milwaukee’s inability to close out tight games on the road has become a clear weakness, one that opponents have increasingly exploited. Manager Pat Murphy has tried to shuffle lineups and adjust roles in the bullpen, but without early leads and more consistent run support, the formula that worked earlier in the year is simply not producing the same results. Facing the struggling Pittsburgh Pirates offers the Brewers a chance to get back on track, but nothing can be taken for granted, particularly at PNC Park where Milwaukee has seen mixed results in past seasons. If the Brewers are going to turn the tide, they’ll need a sharp outing from their starting pitcher, early offensive output to ease the pressure on the bullpen, and cleaner defensive play that avoids gifting the Pirates extra outs. Milwaukee still has the talent to contend and remain in the division race, but games like this are critical litmus tests for a team trying to determine whether it can rebound and remain competitive, or continue a slide that puts them in a midseason hole. A win over Pittsburgh won’t solve all of Milwaukee’s issues, but it would represent a much-needed step forward and perhaps help jumpstart a team that’s too talented to be hovering below .500 for much longer.

On May 23, 2025, the Milwaukee Brewers will face the Pittsburgh Pirates at PNC Park in Pittsburgh, Pennsylvania. This National League Central matchup features two teams aiming to improve their standings in the division. Milwaukee vs Pittsburgh AI Prediction: Free MLB Betting Insights for May 23. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Pittsburgh Pirates MLB Preview

The Pittsburgh Pirates enter their May 23 home matchup against the Milwaukee Brewers at PNC Park with a 15–32 record and a season that has largely unraveled due to poor run production, shaky defense, and an overmatched pitching staff that has been unable to contain even average offensive opponents, making every game a steep climb from the outset. Despite small flashes of competitiveness, including a 4–6 record in their last 10 home games, the Pirates remain firmly in last place in the National League Central and have the worst against-the-spread (ATS) record in the majors at 15–32, covering just 31.9% of the time, a clear reflection of their struggles to remain competitive in most matchups. Offensively, Pittsburgh has been unable to generate consistent pressure on opposing pitchers, with long scoring droughts, a lack of plate discipline, and limited power output, often leaving them relying on scattered solo home runs or isolated rallies to stay in games, and without a true offensive centerpiece stepping up, the burden has shifted unfairly to an already thin pitching rotation. The Pirates’ starting pitching has been largely ineffective, with few quality starts and multiple games where opposing lineups have built early leads, forcing Pittsburgh to play from behind—a scenario that has repeatedly exposed their bullpen’s lack of depth and efficiency in handling high-leverage situations.

Defensively, the Pirates have been plagued by mental errors and sloppy execution, turning routine plays into extended innings and providing extra opportunities for opposing offenses that don’t need much help in building momentum. Manager Derek Shelton has tried to keep the team engaged with lineup changes and positional flexibility, but the lack of veteran leadership and inexperience in crucial game situations continues to show, especially against disciplined and balanced teams like the Brewers. Hosting Milwaukee presents both a challenge and a slim opportunity—on one hand, the Brewers are slumping and vulnerable, giving Pittsburgh a theoretical chance to steal a win if they can play a cleaner, more focused game; on the other hand, the Pirates have shown little evidence that they can string together the kind of complete performance necessary to win even against other struggling teams. To compete in this game, Pittsburgh will need a quality start from whoever takes the mound, better execution with runners on base, and a defense that doesn’t beat itself, all of which have been elusive up to this point in the season. While the long-term outlook for 2025 is quickly shifting toward development and evaluation of young talent, these divisional matchups still matter for a team trying to establish identity, pride, and the foundation of future competitiveness. A win over the Brewers wouldn’t drastically change Pittsburgh’s trajectory, but it would serve as a small step forward for a team that simply needs something positive to build on in what has already become a lost season.

Milwaukee vs. Pittsburgh Prop Picks (AI)

Remi is pouring through loads of stats on each player. In fact, anytime the Brewers and Pirates play there’s always several intriguing angles to key in on. Not to mention games played at PNC Park in May can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: F. Peralta over 22.5 Fantasy Score.

Milwaukee vs. Pittsburgh Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over millions of data from every facet between the Brewers and Pirates and using recursive machine learning and impressive AI to boil down the data to a single cover probability.

Interestingly enough, the data has been most watching on the unproportionally assigned weight emotional bettors tend to put on player performance factors between a Brewers team going up against a possibly improved Pirates team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Milwaukee vs Pittsburgh picks, computer picks Brewers vs Pirates, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Brewers Betting Trends

The Milwaukee Brewers have a 3–7 record against the run line in their last 10 games.

Pirates Betting Trends

The Pittsburgh Pirates have a 4–6 record against the run line in their last 10 home games.

Brewers vs. Pirates Matchup Trends

The Brewers have a 24–26 record against the run line this season, covering 48% of the time. The Pirates have a 15–32 record against the run line this season, covering 31.9% of the time.

Milwaukee vs. Pittsburgh Game Info

Milwaukee vs Pittsburgh starts on May 23, 2025 at 6:40 PM EST.

Spread: Pittsburgh +1.5
Moneyline: Milwaukee +105, Pittsburgh -125
Over/Under: 7

Milwaukee: (25-26)  |  Pittsburgh: (17-34)

Remi's searched hard and found the best prop for this matchup: F. Peralta over 22.5 Fantasy Score.. Prices move—always shop for the best number.

The Brewers have a 24–26 record against the run line this season, covering 48% of the time. The Pirates have a 15–32 record against the run line this season, covering 31.9% of the time.

MIL trend: The Milwaukee Brewers have a 3–7 record against the run line in their last 10 games.

PIT trend: The Pittsburgh Pirates have a 4–6 record against the run line in their last 10 home games.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Milwaukee vs. Pittsburgh Odds

Remi is pouring through tons of data points on each line. In fact, anytime the Milwaukee vs Pittsburgh trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable betting trends.

Milwaukee vs Pittsburgh Opening Odds

MIL Moneyline: +105
PIT Moneyline: -125
MIL Spread: -1.5
PIT Spread: +1.5
Over/Under: 7

Milwaukee vs Pittsburgh Live Odds

Games PTS ML SPR O/U
In Progress
Baltimore Orioles
New York Yankees
In Progress
Orioles
Yankees
0
3
+950
-2000
+3.5 (+100)
-3.5 (-130)
O 6.5 (-140)
U 6.5 (+105)
In Progress
St Louis Cardinals
Chicago Cubs
In Progress
Cardinals
Cubs
0
0
 
-185
 
-1.5 (+105)
O 9.5 (-125)
U 9.5 (-105)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+140
-170
+1.5 (-155)
-1.5 (+130)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
Nationals
-105
-115
-1.5 (+150)
+1.5 (-180)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+190
-235
+1.5 (-105)
-1.5 (-115)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-140
+115
-1.5 (+125)
+1.5 (-150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+105
-125
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+175
-215
+1.5 (-115)
-1.5 (-105)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+110
-130
+1.5 (-195)
-1.5 (+160)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+145
-175
+1.5 (-150)
-1.5 (+125)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+120
-145
+1.5 (-190)
-1.5 (+155)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-180)
-1.5 (+150)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-145
+120
-1.5 (+110)
+1.5 (-130)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
-1.5 (+175)
+1.5 (-215)
O 7 (-115)
U 7 (-105)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-115)
U 10 (-105)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Milwaukee Brewers vs. Pittsburgh Pirates on May 23, 2025 at PNC Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS