Mets vs. Red Sox
Prediction, Odds & Props
May 20 | MLB AI Picks

Updated: 2025-05-18T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New York Mets and Boston Red Sox face off on May 20, 2025, at Fenway Park in the second game of their three-game interleague series. The Mets, leading the NL East, aim to maintain their momentum, while the Red Sox look to bounce back and improve their standing in the AL East.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 20, 2025

Start Time: 6:45 PM EST​

Venue: Fenway Park​

Red Sox Record: (24-25)

Mets Record: (29-19)

OPENING ODDS

NYM Moneyline: -125

BOS Moneyline: +105

NYM Spread: -1.5

BOS Spread: +1.5

Over/Under: 9

NYM
Betting Trends

  • The New York Mets have a 4-5 record against the run line on the road this season. 

BOS
Betting Trends

  • The Boston Red Sox hold a 3-7 record against the spread over their past 10 games.

MATCHUP TRENDS

  • Despite recent struggles, the Red Sox have a 13-11 home record, suggesting a slight edge when playing at Fenway Park.

NYM vs. BOS
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Soto over 7.5 Fantasy Score.

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New York Mets vs Boston Prediction & Odds:
Free MLB Betting Insights for 5/20/25

The May 20, 2025 matchup between the New York Mets and Boston Red Sox at Fenway Park continues an intriguing interleague series that pits one of the National League’s most consistent performers against an American League team trying to stabilize in a tough division. The Mets enter the game with a 29-18 record, leading the NL East behind a potent combination of veteran power, timely hitting, and a pitching staff that has quietly anchored their success. Their offense is led by Pete Alonso, who is hitting .302 with 9 home runs and 31 RBIs, and Juan Soto, who has added 8 homers, 28 RBIs, and an impressive .826 OPS. Together with Francisco Lindor, who provides both power (9 HRs) and speed (6 stolen bases), the Mets have formed a dangerous heart of the order that punishes mistakes and capitalizes on scoring opportunities. On the mound, Clay Holmes (3.14 ERA) is expected to start, a rare transition to the rotation from his previous role as a reliever, where he had success with the Yankees. Holmes’ pitch mix and ability to induce ground balls may play well against a Red Sox team that thrives on hard contact. Defensively, the Mets have been solid, and their bullpen has played a major role in preserving tight wins, often shutting down rallies and closing games with efficiency.

Meanwhile, the Boston Red Sox arrive with a 23-25 record and are still seeking consistency in all phases of the game. Offensively, they have firepower, ranking top 10 in wRC+ and wOBA, largely thanks to the contributions of Rafael Devers and Trevor Story. Devers remains one of the league’s most feared left-handed bats, while Story is enjoying a bounce-back campaign with multi-hit games and consistent run production. The Red Sox are slated to start Walker Buehler, who is continuing his return to form after missing time earlier in the season. Buehler’s command and experience could be crucial against a patient and powerful Mets lineup that doesn’t chase and has multiple hitters capable of changing the game with one swing. Boston’s bullpen, however, has been unreliable—giving up late leads and struggling to execute in tight spots—which has played a major role in their 3-7 record ATS in their last 10 games. Their 13-11 home record at Fenway offers some encouragement, and the quirky dimensions of the park always add an element of unpredictability. For the Red Sox to win, they’ll need early runs, a clean outing from Buehler, and improved bullpen management. The Mets, on the other hand, will look to apply pressure early, work deep counts, and rely on their bullpen to seal things if they have the lead late. This game features stars on both sides, potential for offensive fireworks, and critical implications for momentum as both teams jockey for position in competitive divisions. While the Mets have the edge on paper, Fenway Park has a history of leveling the playing field—and if the Red Sox find rhythm at the plate, this could become a back-and-forth, high-scoring affair worthy of primetime attention.

New York Mets Mets MLB Preview

The New York Mets continue to roll into the heart of the 2025 season with one of the National League’s most balanced rosters and a 29-18 record that reflects their blend of power, discipline, and depth. Sitting atop the NL East, the Mets have excelled thanks to a lineup that consistently applies pressure, a pitching staff that limits damage, and a bullpen that reliably shuts the door. Pete Alonso continues to be the offensive anchor, mashing his way to a .302 batting average with 9 home runs and 31 RBIs, delivering not just power but improved contact and a stronger two-strike approach. Alongside him, Juan Soto has been his usual self—patient, powerful, and productive—contributing an .826 OPS, 8 home runs, and a team-high 28 RBIs, while Francisco Lindor has added another dimension with 9 home runs, 6 steals, and his characteristic defensive prowess up the middle. The top of the Mets lineup sets the tone early, with frequent extra-base hits and one of the lowest strikeout rates in the NL, forcing opposing pitchers into high-stress innings from the jump. Rookie Brett Baty and veteran Jeff McNeil provide depth in the order, capable of flipping the lineup over and extending rallies, giving manager Carlos Mendoza the luxury of quality plate appearances throughout the order. On the mound, Clay Holmes is expected to make a rare start, transitioning from his usual bullpen role where he’s thrived with a 3.14 ERA and a sinker that generates weak contact.

The decision to use Holmes in this spot reflects confidence in his ability to induce ground balls and navigate Boston’s powerful but inconsistent lineup. The Mets’ bullpen remains one of the team’s greatest strengths, with Edwin Díaz anchoring the ninth and setup men like Brooks Raley and Drew Smith excelling in tight, late-game situations. Defensively, New York has been sharp—ranking among the league leaders in team fielding percentage—thanks to solid fundamentals and consistent positioning. Though their 12-13 road record suggests a slight dip in performance away from Citi Field, the Mets have won six of their last eight on the road, including tight series in Philadelphia and Milwaukee, and enter Fenway Park with growing confidence. The game plan against Boston will focus on pitch efficiency early, minimizing middle-of-the-plate mistakes to dangerous hitters like Rafael Devers and capitalizing on the Red Sox bullpen, which has been vulnerable in late innings. Holmes will look to pitch to contact, trust his infield defense, and set up favorable matchups for the bullpen. If the offense continues to grind out at-bats and deliver with runners in scoring position, the Mets are well-positioned to continue their winning ways. With a healthy core, emerging young talent, and a bullpen that shortens games, New York appears poised not only to leave Fenway with a series win but also to solidify their status as one of the NL’s most complete and dangerous clubs heading into the summer months.

The New York Mets and Boston Red Sox face off on May 20, 2025, at Fenway Park in the second game of their three-game interleague series. The Mets, leading the NL East, aim to maintain their momentum, while the Red Sox look to bounce back and improve their standing in the AL East. New York Mets vs Boston AI Prediction: Free MLB Betting Insights for May 20. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Boston Red Sox MLB Preview

The Boston Red Sox enter their May 20 clash with the New York Mets clinging to the hope of finding sustained traction in a turbulent 2025 season, bringing a 23-25 record into Fenway Park and desperately seeking consistency in all facets of their game. While their offense has shown flashes of being among the league’s most potent—ranking top 10 in both weighted runs created plus (wRC+) and weighted on-base average (wOBA)—defensive miscues, bullpen collapses, and starting rotation instability have undermined their efforts to stay competitive in the American League East. At the heart of their offensive production stands Rafael Devers, who remains the most feared bat in the lineup with his ability to launch balls over the Monster and work deep counts. Trevor Story has also begun to find rhythm after a slow start, driving in runs and anchoring the infield with more consistent defensive work. Outfielder Jarren Duran continues to emerge as a valuable spark plug with his blend of speed, contact, and aggressive baserunning, giving manager Alex Cora more options atop the order. But the Red Sox have not capitalized consistently enough on scoring opportunities, often stranding runners and allowing opposing teams to creep back into games they had early control of. On the mound, Boston hands the ball to Walker Buehler, who is still working back to full form following his return from injury.

Buehler’s stuff remains electric, and his postseason experience gives the Red Sox a dependable presence when he’s commanding the zone, but inconsistency with his fastball location and early inning traffic have limited his efficiency. Against a Mets lineup packed with patient, power-heavy hitters like Pete Alonso and Juan Soto, Buehler must avoid falling behind in counts or leaving pitches over the heart of the plate. The biggest concern for Boston remains its bullpen, which has surrendered multiple leads over the past two weeks and posted one of the higher WHIPs in late-inning situations. Relievers have struggled to consistently throw strikes, and the lack of a lockdown closer has forced Cora to mix and match depending on matchups, which hasn’t always worked in their favor. Fenway Park, however, remains one of their few steady advantages. At 13-11 at home, the Red Sox play with noticeably more energy and often generate more offensive flow in front of a passionate and vocal fan base. If the offense can jump on Clay Holmes early—especially given that he’s transitioning from a bullpen role to a starter’s workload—Boston could tilt the momentum in their favor. But it will require a clean game from the defense, six solid innings from Buehler, and for the bullpen to step up and finish the job. The Red Sox know they’re treading water in a competitive division and need series like this one to turn their season around. With Fenway’s quirks, Buehler’s upside, and the firepower to hang with anyone, Boston is fully capable of rising to the challenge—but only if they can finally synchronize their offense, pitching, and late-game execution.

New York Mets vs. Boston Prop Picks (AI)

Remi is pouring through tons of datapoints on each team. In fact, anytime the Mets and Red Sox play there’s always several intriguing angles to key in on. Not to mention games played at Fenway Park in May rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: J. Soto over 7.5 Fantasy Score.

New York Mets vs. Boston Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every angle between the Mets and Red Sox and using recursive machine learning and cutting-edge AI to boil down the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most focused on the linear correlation of factor human bettors tend to put on New York Mets’s strength factors between a Mets team going up against a possibly deflated Red Sox team. In reality, the true game analytics might reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI New York Mets vs Boston picks, computer picks Mets vs Red Sox, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Mets Betting Trends

The New York Mets have a 4-5 record against the run line on the road this season. 

Red Sox Betting Trends

The Boston Red Sox hold a 3-7 record against the spread over their past 10 games.

Mets vs. Red Sox Matchup Trends

Despite recent struggles, the Red Sox have a 13-11 home record, suggesting a slight edge when playing at Fenway Park.

New York Mets vs. Boston Game Info

New York Mets vs Boston starts on May 20, 2025 at 6:45 PM EST.

Spread: Boston +1.5
Moneyline: New York Mets -125, Boston +105
Over/Under: 9

New York Mets: (29-19)  |  Boston: (24-25)

Remi's searched hard and found the best prop for this matchup: J. Soto over 7.5 Fantasy Score.. Prices move—always shop for the best number.

Despite recent struggles, the Red Sox have a 13-11 home record, suggesting a slight edge when playing at Fenway Park.

NYM trend: The New York Mets have a 4-5 record against the run line on the road this season. 

BOS trend: The Boston Red Sox hold a 3-7 record against the spread over their past 10 games.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

New York Mets vs. Boston Odds

AI algorithm Remi is pouring through mountains of stats on each player. In fact, anytime the New York Mets vs Boston trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.

New York Mets vs Boston Opening Odds

NYM Moneyline: -125
BOS Moneyline: +105
NYM Spread: -1.5
BOS Spread: +1.5
Over/Under: 9

New York Mets vs Boston Live Odds

Games PTS ML SPR O/U
In Progress
Baltimore Orioles
New York Yankees
In Progress
Orioles
Yankees
0
3
+900
-1800
+4.5 (-150)
-4.5 (+115)
O 7.5 (-130)
U 7.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-169
 
-1.5 (+113)
O 9.5 (-113)
U 9.5 (-102)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+147
-163
+1.5 (-143)
-1.5 (+127)
O 8.5 (-102)
U 8.5 (-113)
Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
Nationals
-105
-105
+1.5 (-207)
-1.5 (+181)
O 8.5 (-110)
U 8.5 (-104)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+201
-225
+1.5 (-103)
-1.5 (-111)
O 8 (-104)
U 8 (-110)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-131
+119
-1.5 (+127)
+1.5 (-143)
O 8 (-102)
U 8 (-113)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+107
-118
+1.5 (-190)
-1.5 (+166)
O 8.5 (-107)
U 8.5 (-107)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+184
-205
+1.5 (-112)
-1.5 (-102)
O 8.5 (-110)
U 8.5 (-104)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+114
-126
+1.5 (-185)
-1.5 (+162)
O 8 (-107)
U 8 (-107)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+150
-166
+1.5 (-141)
-1.5 (+125)
O 8 (-102)
U 8 (-113)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+125
-138
+1.5 (-183)
-1.5 (+161)
O 7 (-118)
U 7 (+103)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+122
-135
+1.5 (-177)
-1.5 (+156)
O 7.5 (-116)
U 7.5 (+101)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-138
+125
-1.5 (+117)
+1.5 (-132)
O 9 (-107)
U 9 (-107)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+104
-115
+1.5 (-209)
-1.5 (+182)
O 7 (-113)
U 7 (-102)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+107
-118
+1.5 (-190)
-1.5 (+166)
O 10 (-114)
U 10 (-101)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Mets Mets vs. Boston Red Sox on May 20, 2025 at Fenway Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS