Nationals vs. Reds
Prediction, Odds & Props
May 04 | MLB AI Picks

Updated: 2025-05-02T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Washington Nationals (15-19) face the Cincinnati Reds (18-16) on Sunday, May 4, 2025, at Great American Ball Park, concluding their three-game series. With the series tied 1-1, both teams aim to secure the series win in this pivotal matchup.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 04, 2025

Start Time: 4:10 PM EST​

Venue: Great American Ball Park​

Reds Record: (18-16)

Nationals Record: (15-19)

OPENING ODDS

WAS Moneyline: +101

CIN Moneyline: -122

WAS Spread: +1.5

CIN Spread: -1.5

Over/Under: 8.5

WAS
Betting Trends

  • The Nationals have a 17-14 record against the spread (ATS) this season, demonstrating competitive play, especially when entering games as underdogs.

CIN
Betting Trends

  • The Reds boast an 18-14 ATS record, indicating consistent performance relative to betting expectations.

MATCHUP TRENDS

  • In games with an over/under set at 8.5 runs, the Reds have seen the total go over in 15 of their 32 games this season, suggesting a tendency toward higher-scoring affairs.

WAS vs. CIN
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Trevino over 0.5 Total Bases.

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Washington vs Cincinnati Prediction & Odds:
Free MLB Betting Insights for 5/4/25

The Washington Nationals and Cincinnati Reds will face off in the rubber match of their three-game series on Sunday, May 4, 2025, at Great American Ball Park in a matchup that features two teams trending in opposite directions but still closely aligned in terms of competitive fire and overall output. The Nationals enter the contest with a 15-19 record and a surprising edge in competitiveness considering preseason expectations, having gone 17-14 against the spread and displaying flashes of offensive promise despite pitching inconsistencies. Their ability to keep games close and occasionally steal wins on the backs of young talents like James Wood, who has belted 9 home runs with 21 RBIs, and Nathaniel Lowe, who leads the team in RBIs with 27, has kept them from sinking into irrelevance early. Washington’s offense averages 4.2 runs per game and has found ways to stay scrappy and opportunistic, although their pitching, particularly in the bullpen, has been their Achilles’ heel, with a team ERA of 5.21 that ranks near the bottom of the league. On Sunday, they’ll turn to left-hander MacKenzie Gore, who owns a 2-3 record and a solid 3.51 ERA with 59 strikeouts over 41 innings; his high strikeout rate gives Washington a fighting chance, especially against an aggressive Cincinnati lineup that can be prone to chasing out of the zone. The Reds, sitting at 18-16 and just above .500, have had a more well-rounded performance so far this season, both offensively and on the mound, with an average of 5.1 runs per game and a team ERA of 3.64, which has kept them in nearly every contest.

Their offense is powered by the electrifying Elly De La Cruz, who leads the team with 25 RBIs and continues to be a spark plug both at the plate and on the basepaths, while Gavin Lux contributes consistently with a .330 OBP. Cincinnati’s starting pitcher, Nick Martinez, enters with a 1-3 record and a 4.68 ERA, but has the ability to mix pitches effectively and generate soft contact, though he’ll need to be sharper than he has been in previous outings to contain the Nationals’ patient hitters. Defensively, the Reds have been more disciplined and consistent than their opponents, and their 18-14 ATS record reflects their ability to outperform betting expectations. Games at Great American Ball Park often skew toward higher scores, and with the Reds having seen the over hit in 15 of their 32 contests with an 8.5-run total line, Sunday has the potential to be another high-scoring affair if either starter falters early. The key battle will likely be decided by which starter can navigate through the opposing middle of the order without damage and which bullpen can lock down the late innings—an area that gives the edge to Cincinnati. For the Nationals to win, they’ll need Gore to continue missing bats and keep De La Cruz off the bases, while hoping their bats can jump on Martinez early. For the Reds, if they can provide Martinez with run support and avoid bullpen meltdowns, they’ll be in prime position to close out the series with a victory and continue building momentum in the NL Central.

Washington Nationals MLB Preview

The Washington Nationals come into Sunday’s series finale against the Cincinnati Reds with a 15-19 record and a chip on their shoulder, playing well above early-season expectations thanks to a blend of youthful energy, competitive grit, and flashes of upside that have helped them remain more than just a pesky underdog in the National League. Their 17-14 record against the spread is a testament to how often they’ve kept games close, and while wins have been hard to string together, there’s no question that this is a team that competes hard and doesn’t give in easily. At the heart of the Nationals’ offense is emerging slugger James Wood, who has burst onto the scene with 9 home runs and 21 RBIs, giving Washington the middle-of-the-order threat it has lacked in recent years and anchoring a lineup that also includes the consistent Nathaniel Lowe, who leads the team with 27 RBIs and continues to be a stabilizing presence. Keibert Ruiz has contributed with a .291 batting average, providing another source of contact and timely hitting, but the Nationals have yet to develop the depth needed to consistently produce throughout the order, making every clutch hit and extra-base opportunity critical. Sunday’s starting pitcher, MacKenzie Gore, has been one of the bright spots on the roster, carrying a 2-3 record with a respectable 3.51 ERA and an impressive 59 strikeouts across just 41 innings pitched.

Gore’s ability to generate swings and misses makes him a true asset in matchups like this, especially against a Reds lineup that can be aggressive and prone to chasing pitches out of the zone. However, the Nationals’ biggest challenge remains their bullpen and overall run prevention, with a team ERA of 5.21 and too many late-game leads slipping away due to inconsistent relief outings and defensive miscues. Gore will likely be asked to work deep into the game, and his performance could determine whether Washington stays in control or is forced to rely on a bullpen that has not consistently held its own. The Nationals’ defense has also been spotty, and against a team like Cincinnati that can apply pressure on the basepaths and exploit defensive lapses, clean execution will be paramount. Offensively, the Nationals must be aggressive early, particularly against Nick Martinez, whose 4.68 ERA suggests vulnerability if hitters are selective and take advantage of his occasional command issues. If Wood and Lowe can set the tone and Gore delivers his typical punchout-heavy performance, the Nationals will have a real shot at walking away with a series win and a much-needed confidence boost. For a team still trying to forge an identity and prove they can be more than a rebuilding roster, games like Sunday’s offer the chance to both steal momentum and make a statement that they aren’t to be overlooked, even against stronger lineups and in hostile ballparks.

The Washington Nationals (15-19) face the Cincinnati Reds (18-16) on Sunday, May 4, 2025, at Great American Ball Park, concluding their three-game series. With the series tied 1-1, both teams aim to secure the series win in this pivotal matchup. Washington vs Cincinnati AI Prediction: Free MLB Betting Insights for May 04. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Cincinnati Reds MLB Preview

The Cincinnati Reds enter Sunday’s series finale against the Washington Nationals with an 18-16 record and a strong sense of momentum as they look to build off a solid first month of play and take the rubber match in front of their home crowd at Great American Ball Park. The Reds have combined electric young talent with veteran presence to put together a well-balanced offensive attack that has averaged 5.1 runs per game, and their 18-14 record against the spread shows they’ve consistently outperformed expectations in a variety of matchups. Leading the way is Elly De La Cruz, whose dynamic skill set has made him one of the most exciting players in baseball—his 25 RBIs and consistent extra-base power have anchored the middle of the order and provided the kind of spark that keeps opposing pitchers on edge. De La Cruz is complemented by Gavin Lux, who has posted a .330 on-base percentage and continues to be a reliable table-setter at the top of the lineup, allowing the Reds to manufacture runs even when the long ball isn’t in play. On the mound, Cincinnati will turn to Nick Martinez, who brings a 1-3 record and 4.68 ERA into Sunday’s contest, and while his numbers haven’t been overpowering, his ability to induce soft contact and keep hitters off balance with a mix of fastballs, cutters, and changeups has given the Reds a chance in most of his starts.

Martinez’s biggest challenge has been avoiding the one big inning, and with a Washington lineup that includes emerging power threats like James Wood and contact hitters like Nathaniel Lowe, pitch sequencing and first-pitch strikes will be critical to his success. The Reds’ bullpen has been generally steady, with Alexis Díaz continuing to handle closing duties effectively, and if Martinez can give them five or six solid innings, manager David Bell has multiple options to manage high-leverage situations in the late innings. Defensively, the Reds have cleaned up many of the issues that plagued them in previous seasons, with improved infield range and outfield coverage contributing to their 3.64 team ERA, a number that has helped them close out tight games and stay competitive against high-scoring opponents. At home, the Reds have played with confidence, using the dimensions of Great American Ball Park to their advantage by creating offensive pressure with aggressive base running, timely hitting, and a flair for the dramatic. The team’s ability to respond in clutch moments, especially with runners in scoring position, has made them tough to beat in back-and-forth games, and they’ll look to bring that same energy and execution into Sunday’s finale. A win would push them further above .500 and add another series victory to their early-season résumé, solidifying their status as a team to watch in the NL Central. With a balanced lineup, a manageable pitching matchup, and a supportive home crowd, the Reds are well-positioned to wrap up this series with authority and continue building on their early-season success.

Washington vs. Cincinnati Prop Picks (AI)

Remi is pouring through mountains of stats on each player. In fact, anytime the Nationals and Reds play there’s always several intriguing observations to key in on. Not to mention games played at Great American Ball Park in May can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: J. Trevino over 0.5 Total Bases.

Washington vs. Cincinnati Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every angle between the Nationals and Reds and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most keyed in on the unproportionally assigned weight human bettors tend to put on Washington’s strength factors between a Nationals team going up against a possibly improved Reds team. Trends look to say the true game analytics appear to reflect a slight lean against one Vegas line specifically.

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Below is our current AI Washington vs Cincinnati picks, computer picks Nationals vs Reds, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Nationals Betting Trends

The Nationals have a 17-14 record against the spread (ATS) this season, demonstrating competitive play, especially when entering games as underdogs.

Reds Betting Trends

The Reds boast an 18-14 ATS record, indicating consistent performance relative to betting expectations.

Nationals vs. Reds Matchup Trends

In games with an over/under set at 8.5 runs, the Reds have seen the total go over in 15 of their 32 games this season, suggesting a tendency toward higher-scoring affairs.

Washington vs. Cincinnati Game Info

Washington vs Cincinnati starts on May 04, 2025 at 4:10 PM EST.

Venue: Great American Ball Park.

Spread: Cincinnati -1.5
Moneyline: Washington +101, Cincinnati -122
Over/Under: 8.5

Washington: (15-19)  |  Cincinnati: (18-16)

Remi's searched hard and found the best prop for this matchup: J. Trevino over 0.5 Total Bases.. Prices move—always shop for the best number.

In games with an over/under set at 8.5 runs, the Reds have seen the total go over in 15 of their 32 games this season, suggesting a tendency toward higher-scoring affairs.

WAS trend: The Nationals have a 17-14 record against the spread (ATS) this season, demonstrating competitive play, especially when entering games as underdogs.

CIN trend: The Reds boast an 18-14 ATS record, indicating consistent performance relative to betting expectations.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Washington vs. Cincinnati Odds

AI algorithm Remi is pouring through loads of stats on each player. In fact, anytime the Washington vs Cincinnati trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable patterns.

Washington vs Cincinnati Opening Odds

WAS Moneyline: +101
CIN Moneyline: -122
WAS Spread: +1.5
CIN Spread: -1.5
Over/Under: 8.5

Washington vs Cincinnati Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-175
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+140
-170
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-190)
-1.5 (+155)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
-1.5 (+170)
+1.5 (-205)
O 7.5 (-110)
U 7.5 (-110)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Washington Nationals vs. Cincinnati Reds on May 04, 2025 at Great American Ball Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN