Mets vs. Cardinals
Prediction, Odds & Props
May 04 | MLB AI Picks

Updated: 2025-05-02T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The New York Mets (22-11) and the St. Louis Cardinals (14-19) conclude their four-game series at Busch Stadium on Sunday, May 4, 2025. The Mets, aiming for a series sweep, will debut top pitching prospect Blade Tidwell, while the Cardinals counter with right-hander Erick Fedde.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: May 04, 2025

Start Time: 1:15 PM EST​

Venue: Busch Stadium​

Cardinals Record: (14-19)

Mets Record: (22-11)

OPENING ODDS

NYM Moneyline: -131

STL Moneyline: +111

NYM Spread: -1.5

STL Spread: +1.5

Over/Under: 8.5

NYM
Betting Trends

  • The Mets have a 22-11 overall record, with a 9-8 record on the road. They’ve been consistent against the spread (ATS), covering in 18 of their 33 games this season.

STL
Betting Trends

  • The Cardinals hold a 14-19 overall record, with a 10-6 record at home. They’ve struggled ATS, covering in just 14 of their 33 games this season.

MATCHUP TRENDS

  • In the last five head-to-head matchups, the Mets have covered the spread in four games. Additionally, the total has gone over in three of those five games, indicating a trend towards higher-scoring affairs.

NYM vs. STL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: W. Contreras over 0.5 Total Bases.

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New York Mets vs St. Louis Prediction & Odds:
Free MLB Betting Insights for 5/4/25

The New York Mets and St. Louis Cardinals close out their four-game series on Sunday, May 4, 2025, at Busch Stadium in what sets up to be a potentially lopsided finale given the current form of both clubs. The Mets enter the contest riding high with a 22-11 record, seeking a sweep of the reeling Cardinals, who have fallen to 14-19 after dropping the first three games of the series. With a strong offensive surge, efficient bullpen management, and stellar starting pitching, New York has outclassed St. Louis in virtually every facet through the first three games, outscoring them by a wide margin. One of the most intriguing elements heading into this game is the debut of Mets’ top pitching prospect Blade Tidwell, who brings electric stuff to the mound with a high-90s fastball and a devastating sweeper that’s already baffled minor league hitters. In his last two Triple-A starts, Tidwell recorded 18 strikeouts and issued just one walk, signaling his readiness for the big stage and adding an extra layer of anticipation for Sunday’s showdown. The Cardinals, meanwhile, are handing the ball to Erick Fedde, who has battled inconsistency throughout the early season. Despite showing flashes of command, Fedde has allowed 16 walks over 32.2 innings and is coming off a rocky outing where he surrendered seven earned runs, putting pressure on him to deliver a much-needed rebound performance for St. Louis.

The Mets’ offense continues to hum, powered by Pete Alonso’s dominant stretch—his .345 average, eight homers, and 30 RBIs speak to his clutch production, but he’s had ample support from Francisco Lindor, Starling Marte, and Brett Baty, who are all contributing with timely hits and smart base running. On the flip side, the Cardinals’ bats have been quiet throughout the series, unable to string together rallies or provide consistent protection for their middle-of-the-lineup threats like Lars Nootbaar and Brendan Donovan. St. Louis will need more from Paul Goldschmidt and Nolan Arenado, both of whom have been relatively silent in this series, and the team as a whole must find a way to solve New York’s pitching while minimizing their own defensive miscues. Sunday’s matchup heavily favors New York on paper, not just due to their superior record, but because of the momentum and confidence they carry into the finale. That said, with the unpredictability of a rookie making his debut and the ever-volatile nature of baseball, the Cardinals will hope to pounce early and shake Tidwell’s rhythm before he settles in. However, if the Mets continue to play the clean, high-IQ baseball that’s defined their season so far, they have an excellent chance to close out the sweep and head back to Citi Field with a 23rd win in the books. This game offers the Cardinals a chance to show resilience and avoid a demoralizing home sweep, while the Mets look to extend their dominance and further assert themselves as legitimate NL contenders.

New York Mets Mets MLB Preview

The New York Mets enter the series finale against the St. Louis Cardinals with momentum firmly on their side and a chance to cap off a four-game sweep that would further solidify their position among the National League’s early-season elite. At 22-11, the Mets are firing on all cylinders, showing a balanced attack built around elite starting pitching, power hitting, and timely situational execution. Sunday’s game brings added intrigue as the organization turns to top pitching prospect Blade Tidwell to make his major league debut. Tidwell, a highly regarded right-hander with a fastball that touches the upper 90s and a sweeper that consistently draws swings and misses, has been dominant in the minors, striking out 18 batters and walking just one over his last two Triple-A starts. The Mets are confident that his command and composure will translate quickly, and he’ll be backed by one of the league’s most productive offenses. Pete Alonso is off to a blistering start, slashing .345 with eight home runs and 30 RBIs, and his ability to drive in runs has anchored a lineup that rarely gives opposing pitchers a breather. Francisco Lindor has quietly found his rhythm at the plate while continuing to shine defensively, and young hitters like Brett Baty and Francisco Alvarez are beginning to show consistency that deepens the order and provides quality at-bats in crucial situations.

The Mets’ offense has done an excellent job working counts, getting into bullpens early, and capitalizing on mistakes, something that could be key against Erick Fedde, who has battled control issues throughout the season. On the mound, New York’s bullpen remains a quiet strength, with Edwin Díaz reclaiming his role as one of the game’s most feared closers and setup men like Brooks Raley and Drew Smith proving dependable in high-leverage spots. Defensively, the Mets have been sharp, limiting errors and executing well on the bases, making them a difficult team to outlast in close games. With the Cardinals reeling and Fedde coming off a rough outing, the Mets have an excellent opportunity to jump out early and let Tidwell settle in with a lead. Manager Carlos Mendoza has preached focus and maturity from his young players, and the team has responded by avoiding extended slumps and showing resilience even in tight contests. With a 9-8 road record and a chance to improve upon that mark, New York sees this game as not just a chance for a sweep but a showcase moment for its next potential ace. If Tidwell can pitch to his pedigree and the offense continues to apply pressure as it has all series long, the Mets will head back to Citi Field with a 23-11 record and even more confidence in a roster that looks increasingly like a legitimate postseason threat in the National League.

The New York Mets (22-11) and the St. Louis Cardinals (14-19) conclude their four-game series at Busch Stadium on Sunday, May 4, 2025. The Mets, aiming for a series sweep, will debut top pitching prospect Blade Tidwell, while the Cardinals counter with right-hander Erick Fedde. New York Mets vs St. Louis AI Prediction: Free MLB Betting Insights for May 04. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

St. Louis Cardinals MLB Preview

The St. Louis Cardinals enter Sunday’s series finale against the New York Mets in urgent need of a response, trailing 0-3 in the four-game set and continuing to struggle with consistency across all phases of their game. With a 14-19 record, they sit below .500 and have yet to find the rhythm that typically defines this franchise’s identity—disciplined pitching, timely hitting, and strong situational baseball. Busch Stadium has historically been a place of strength for the Cardinals, and their 10-6 home record reflects some ability to rally in front of their fans, but they’ve been outplayed in this series by a deeper, more polished Mets squad. Sunday offers a final chance to avoid a demoralizing sweep, and that responsibility falls on the shoulders of veteran right-hander Erick Fedde, who is still trying to find his form this season. After a disastrous start in his last outing where he gave up seven runs, Fedde’s ERA has ballooned, and his 16 walks in just over 32 innings underscore a lack of command that could prove costly against a disciplined Mets lineup that thrives on punishing mistakes. To give their starter any breathing room, the Cardinals’ offense must show far more urgency than it has through the first three games.

Lars Nootbaar has been a bright spot, leading the team with five home runs and 18 RBIs, and his ability to get on base could be vital in setting the tone early. Brendan Donovan remains a steady contributor with his .333 batting average and contact-oriented approach, but the heart of the order—Paul Goldschmidt and Nolan Arenado—must deliver in clutch spots to give St. Louis a fighting chance. The absence of consistent power production and failure to capitalize with runners in scoring position have plagued the team, often leading to one-run losses or mid-game deficits that snowball. On defense, St. Louis has held its own, but untimely errors and shaky bullpen moments have compounded their issues. They’ll also be dealing with an unfamiliar challenge in the form of Mets rookie Blade Tidwell, making his MLB debut, which presents both an opportunity and a dilemma—if the Cardinals can jump on him early and apply pressure, they could flip the momentum, but if they allow him to settle in, their recent offensive struggles could be magnified. Manager Oliver Marmol will need to manage his bullpen carefully and likely play matchups aggressively, especially if Fedde runs into early trouble. For a team with playoff aspirations, Sunday’s game represents more than just avoiding a sweep—it’s about restoring competitive integrity, regaining confidence, and proving they can stand toe-to-toe with one of the National League’s hottest teams. A win would not only prevent the sweep but serve as a much-needed reset before heading into their next series, and the Cardinals know that their veteran core must lead the charge if they hope to salvage pride and direction from an otherwise disappointing homestand.

New York Mets vs. St. Louis Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each player. In fact, anytime the Mets and Cardinals play there’s always several intriguing observations to key in on. Not to mention games played at Busch Stadium in May almost always follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: W. Contreras over 0.5 Total Bases.

New York Mets vs. St. Louis Prediction (AI)

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Remi, our AI sports wizard, has been pouring over tons of data from every angle between the Mets and Cardinals and using recursive machine learning and impressive AI to analyze the data to a single cover probability.

Interestingly enough, the data has been most watching on the linear correlation of weight knucklehead sportsbettors regularly put on New York Mets’s strength factors between a Mets team going up against a possibly healthy Cardinals team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI New York Mets vs St. Louis picks, computer picks Mets vs Cardinals, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Mets Betting Trends

The Mets have a 22-11 overall record, with a 9-8 record on the road. They’ve been consistent against the spread (ATS), covering in 18 of their 33 games this season.

Cardinals Betting Trends

The Cardinals hold a 14-19 overall record, with a 10-6 record at home. They’ve struggled ATS, covering in just 14 of their 33 games this season.

Mets vs. Cardinals Matchup Trends

In the last five head-to-head matchups, the Mets have covered the spread in four games. Additionally, the total has gone over in three of those five games, indicating a trend towards higher-scoring affairs.

New York Mets vs. St. Louis Game Info

New York Mets vs St. Louis starts on May 04, 2025 at 1:15 PM EST.

Spread: St. Louis +1.5
Moneyline: New York Mets -131, St. Louis +111
Over/Under: 8.5

New York Mets: (22-11)  |  St. Louis: (14-19)

Remi's searched hard and found the best prop for this matchup: W. Contreras over 0.5 Total Bases.. Prices move—always shop for the best number.

In the last five head-to-head matchups, the Mets have covered the spread in four games. Additionally, the total has gone over in three of those five games, indicating a trend towards higher-scoring affairs.

NYM trend: The Mets have a 22-11 overall record, with a 9-8 record on the road. They’ve been consistent against the spread (ATS), covering in 18 of their 33 games this season.

STL trend: The Cardinals hold a 14-19 overall record, with a 10-6 record at home. They’ve struggled ATS, covering in just 14 of their 33 games this season.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

New York Mets vs. St. Louis Odds

AI algorithm Remi is pouring through mountains of data on each player. In fact, anytime the New York Mets vs St. Louis trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable patterns.

New York Mets vs St. Louis Opening Odds

NYM Moneyline: -131
STL Moneyline: +111
NYM Spread: -1.5
STL Spread: +1.5
Over/Under: 8.5

New York Mets vs St. Louis Live Odds

Games PTS ML SPR O/U
In Progress
St Louis Cardinals
Chicago Cubs
In Progress
Cardinals
Cubs
3
5
 
-1100
 
-1.5 (-265)
O 9.5 (+115)
U 9.5 (-150)
In Progress
Tampa Bay Rays
Toronto Blue Jays
In Progress
Rays
Blue Jays
0
3
+580
-1000
+2.5 (+125)
-2.5 (-165)
O 6.5 (-140)
U 6.5 (+105)
In Progress
Colorado Rockies
San Francisco Giants
In Progress
Rockies
Giants
2
0
-140
+105
-1.5 (+125)
+1.5 (-165)
O 9.5 (+105)
U 9.5 (-140)
In Progress
New York Mets
Miami Marlins
In Progress
Mets
Marlins
1
0
-590
+340
-3.5 (-108)
+3.5 (-127)
O 11 (-114)
U 11 (-122)
In Progress
Detroit Tigers
Boston Red Sox
In Progress
Tigers
Red Sox
0
0
+110
-145
+1.5 (-200)
-1.5 (+150)
O 7.5 (-120)
U 7.5 (-110)
Sep 27, 2025 4:45PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:45PM
White Sox
Nationals
-110
-110
-1.5 (+155)
+1.5 (-190)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+110
-130
+1.5 (-190)
-1.5 (+155)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+150
-186
+1.5 (-157)
-1.5 (+123)
O 8 (-115)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+120
-145
+1.5 (-195)
-1.5 (+160)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+132
-162
+1.5 (-180)
-1.5 (+138)
O 7.5 (-114)
U 7.5 (-110)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-145
+120
-1.5 (+110)
+1.5 (-130)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
+1.5 (-215)
-1.5 (+175)
O 7 (-115)
U 7 (-105)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+155)
+1.5 (-190)
O 10 (-115)
U 10 (-105)
Sep 28, 2025 3:06PM EDT
Baltimore Orioles
New York Yankees
9/28/25 3:06PM
Orioles
Yankees
+140
-170
+1.5 (-125)
-1.5 (+105)
O 9.5 (+100)
U 9.5 (-120)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers New York Mets Mets vs. St. Louis Cardinals on May 04, 2025 at Busch Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS