Cubs vs. Pirates
Prediction, Odds & Props
Apr 30 | MLB AI Picks

Updated: 2025-04-28T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Chicago Cubs (17–12) and Pittsburgh Pirates (11–18) continue their three-game series on April 30, 2025, at PNC Park, with first pitch scheduled for 6:40 PM ET. The Cubs look to build on their strong start in the NL Central, while the Pirates aim to rebound from recent struggles and gain ground in the division.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 30, 2025

Start Time: 6:40 PM EST​

Venue: PNC Park​

Pirates Record: (11-19)

Cubs Record: (18-12)

OPENING ODDS

CHC Moneyline: -171

PIT Moneyline: +143

CHC Spread: -1.5

PIT Spread: +1.5

Over/Under: 9

CHC
Betting Trends

  • The Cubs have covered the run line in 7 of their last 13 road games, showcasing their ability to perform well away from home.

PIT
Betting Trends

  • The Pirates have covered the run line in 6 of their last 13 home games, indicating challenges in capitalizing on home-field advantage.

MATCHUP TRENDS

  • The Cubs are favored on the moneyline at -174, with the Pirates at +145; the over/under is set at 8.5 runs, suggesting expectations of a moderately high-scoring game.

CHC vs. PIT
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: A. McCutchen over 0.5 Total Bases.

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Chicago Cubs vs Pittsburgh Prediction & Odds:
Free MLB Betting Insights for 4/30/25

The Chicago Cubs and Pittsburgh Pirates meet at PNC Park on April 30, 2025, in the second of a three-game set between two NL Central rivals on very different trajectories. The Cubs enter the matchup with a 17–12 record and a growing sense of confidence as they look to extend their early-season success and reinforce their place atop the division standings. With a balanced roster built around timely offense, solid defense, and an increasingly reliable pitching staff, Chicago has been able to grind out wins in both tight games and high-scoring affairs. On the mound, left-hander Matthew Boyd gets the start and will look to continue his strong run after posting a 2–2 record with a 2.54 ERA across his first five starts. Boyd has been particularly effective against right-handed hitters this season and has shown improved command and pitch efficiency, giving the Cubs a dependable option in the middle of the rotation. Offensively, the Cubs have been paced by Seiya Suzuki, who enters the game with a .298 batting average and seven home runs, along with Ian Happ, whose switch-hitting versatility and 14 RBIs have helped lengthen the lineup and generate consistent run production. With Nico Hoerner getting on base at a high clip and Christopher Morel offering pop in the lower half of the lineup, the Cubs are finding ways to manufacture offense even without monster innings.

On the opposite side, the Pirates continue to flounder at 11–18, struggling to build momentum and plagued by both underperformance and injuries. Their starter, right-hander Carmen Mlodzinski, brings a 1–3 record and an inflated 6.95 ERA into the game, emblematic of a rotation that’s been unable to keep games competitive past the middle innings. Mlodzinski will have to navigate a Cubs lineup that punishes fastballs left over the plate, making his ability to change speeds and work ahead in counts crucial to limiting damage. Oneil Cruz remains the brightest spot in Pittsburgh’s lineup, with his combination of power and speed—eight home runs and 12 stolen bases—making him a constant threat at the plate and on the bases. However, beyond Cruz, the Pirates have struggled with run production, and players like Bryan Reynolds and Ke’Bryan Hayes have yet to deliver with the consistency needed to carry the offense. The Pirates’ bullpen has been overworked, often entering games too early due to short starts, which has further exposed depth issues and contributed to late-game collapses. If the Cubs can score early and force Pittsburgh to the pen by the fifth inning, they’ll be in prime position to take control of the series. With the over/under set at 8.5 runs and the Cubs favored on the moneyline, expectations point toward another productive night for Chicago’s bats and a continuation of Pittsburgh’s frustrating start. For the Cubs, this matchup is about sustaining their winning formula; for the Pirates, it’s a test of resilience and a chance to respond on their home field before the division slips further out of reach.

Chicago Cubs Cubs MLB Preview

The Chicago Cubs travel to PNC Park riding the momentum of a strong April campaign that has them sitting atop the NL Central with a 17–12 record, built on a foundation of balanced offense, steady starting pitching, and improved bullpen reliability. After an offseason that prioritized roster depth and pitching reinforcements, the Cubs have emerged as one of the more complete teams in the early going, showing a rare ability to win tight one-run games while also generating offensive explosions when needed. Left-hander Matthew Boyd gets the start in this second game of the series, and he brings a 2–2 record and a sharp 2.54 ERA into the contest. Boyd has been efficient and poised, holding opposing hitters to a sub-.220 average and routinely navigating high-leverage innings with confidence, using a mix of low-90s fastballs and well-placed off-speed pitches. His success will be crucial against a Pirates lineup that, while struggling, features dangerous athletes like Oneil Cruz capable of flipping momentum with a single swing or stolen base. The Cubs’ offense, meanwhile, continues to roll, spearheaded by Seiya Suzuki, who has settled in as the club’s most consistent hitter with a .298 average and seven home runs. Suzuki’s plate discipline and situational hitting have been difference-makers in close games, and he’s complemented by Ian Happ, whose switch-hitting approach and 14 RBIs make him a versatile presence in the heart of the order.

Nico Hoerner continues to excel at the top of the lineup, setting the tone with a .350 OBP and aggressive base running, while Christopher Morel adds pop and energy in the lower third. Defensively, the Cubs have cleaned up mistakes that cost them games in previous seasons, and their infield, anchored by Dansby Swanson and Hoerner, has turned double plays at one of the highest rates in the National League. The bullpen, once considered a liability, has evolved into a reliable asset, with Adbert Alzolay and Julian Merryweather excelling in high-leverage innings, giving manager Craig Counsell confidence when the game turns late. The team’s approach on the road has been businesslike—score early, pressure opposing starters, and shorten the game with quality relief. Against Pirates starter Carmen Mlodzinski, who brings a 6.95 ERA into the outing, the Cubs will likely hunt early fastballs and look to force him into long at-bats, increasing the chances of reaching Pittsburgh’s vulnerable bullpen by the middle innings. A win here would not only give Chicago a strong shot at a series win but also continue to validate their legitimacy as early-season contenders in a division that’s still wide open. With a blend of discipline, power, and clubhouse cohesion, the Cubs are positioning themselves as a team that not only starts hot—but has the makeup to stay hot.

The Chicago Cubs (17–12) and Pittsburgh Pirates (11–18) continue their three-game series on April 30, 2025, at PNC Park, with first pitch scheduled for 6:40 PM ET. The Cubs look to build on their strong start in the NL Central, while the Pirates aim to rebound from recent struggles and gain ground in the division. Chicago Cubs vs Pittsburgh AI Prediction: Free MLB Betting Insights for Apr 30. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Pittsburgh Pirates MLB Preview

The Pittsburgh Pirates enter the second game of their series against the Chicago Cubs with a 11–18 record and the mounting pressure of a slow start that threatens to derail their season before May. Despite the presence of young talent and flashes of potential, the Pirates have struggled to find consistency in any phase of the game, particularly on the mound, where they’ve been unable to get quality starts with regularity. Right-hander Carmen Mlodzinski will get the ball for this crucial contest, and his early-season numbers—1–3 record and a 6.95 ERA—highlight the issues he’s had keeping hitters off balance and limiting damage. Mlodzinski has had difficulty with pitch location and fastball command, often working from behind in counts and struggling to escape innings cleanly, which has put added pressure on a bullpen that’s been one of the most overworked in the league. Pittsburgh’s relief corps has talent, but they’ve been asked to cover too many innings too often, leading to late-game breakdowns and an inability to protect slim leads. Offensively, Oneil Cruz has been the club’s most reliable threat, posting a .258 average with eight home runs and 12 stolen bases, showing the kind of dynamic ability that makes him a cornerstone for the franchise.

Cruz’s blend of power and speed gives the Pirates a game-changer in the top half of the lineup, but the supporting cast has yet to offer the consistency needed to string together rallies. Players like Bryan Reynolds and Ke’Bryan Hayes have underperformed relative to expectations, and the Pirates have often struggled to produce with runners in scoring position—one of the key reasons they’ve dropped so many close contests. Defensively, the team has been serviceable but unspectacular, and mistakes in the field have occasionally compounded pitching woes, further complicating efforts to stay competitive in games. Facing a division-leading Cubs team that brings power and efficiency to every at-bat, the Pirates will need to play crisp, mistake-free baseball to remain in striking distance. That starts with Mlodzinski getting through the first three innings without a crooked number on the board and the offense manufacturing early pressure to disrupt Matthew Boyd’s rhythm. For manager Derek Shelton, finding a way to squeeze more innings from his starter while generating production beyond Cruz is the blueprint for turning things around. A win in this matchup wouldn’t just prevent a series loss—it could help restore belief in a team that still has potential, but one that’s dangerously close to falling too far behind in a competitive National League. With the home crowd behind them and the motivation to halt their slide, the Pirates have the opportunity to respond, but it will require a collective step forward in every phase of the game.

Chicago Cubs vs. Pittsburgh Prop Picks (AI)

AI algorithm Remi is pouring through mountains of datapoints on each team. In fact, anytime the Cubs and Pirates play there’s always several intriguing trends to key in on. Not to mention games played at PNC Park in Apr rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: A. McCutchen over 0.5 Total Bases.

Chicago Cubs vs. Pittsburgh Prediction (AI)

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Remi, our AI sports wizard, has been pouring over mountains of data from every angle between the Cubs and Pirates and using recursive machine learning and industry leading AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most watching on the unproportionally assigned factor knucklehead sportsbettors tend to put on Chicago Cubs’s strength factors between a Cubs team going up against a possibly healthy Pirates team. It appears the true game analytics appear to reflect a strong lean against one Vegas line in particular.

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Below is our current AI Chicago Cubs vs Pittsburgh picks, computer picks Cubs vs Pirates, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Cubs Betting Trends

The Cubs have covered the run line in 7 of their last 13 road games, showcasing their ability to perform well away from home.

Pirates Betting Trends

The Pirates have covered the run line in 6 of their last 13 home games, indicating challenges in capitalizing on home-field advantage.

Cubs vs. Pirates Matchup Trends

The Cubs are favored on the moneyline at -174, with the Pirates at +145; the over/under is set at 8.5 runs, suggesting expectations of a moderately high-scoring game.

Chicago Cubs vs. Pittsburgh Game Info

Chicago Cubs vs Pittsburgh starts on April 30, 2025 at 6:40 PM EST.

Spread: Pittsburgh +1.5
Moneyline: Chicago Cubs -171, Pittsburgh +143
Over/Under: 9

Chicago Cubs: (18-12)  |  Pittsburgh: (11-19)

Remi's searched hard and found the best prop for this matchup: A. McCutchen over 0.5 Total Bases.. Prices move—always shop for the best number.

The Cubs are favored on the moneyline at -174, with the Pirates at +145; the over/under is set at 8.5 runs, suggesting expectations of a moderately high-scoring game.

CHC trend: The Cubs have covered the run line in 7 of their last 13 road games, showcasing their ability to perform well away from home.

PIT trend: The Pirates have covered the run line in 6 of their last 13 home games, indicating challenges in capitalizing on home-field advantage.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Chicago Cubs vs. Pittsburgh Odds

Remi is pouring through tons of stats on each team. In fact, anytime the Chicago Cubs vs Pittsburgh trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable betting trends.

Chicago Cubs vs Pittsburgh Opening Odds

CHC Moneyline: -171
PIT Moneyline: +143
CHC Spread: -1.5
PIT Spread: +1.5
Over/Under: 9

Chicago Cubs vs Pittsburgh Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+196
-240
+1.5 (-105)
-1.5 (-115)
O 9 (-105)
U 9 (-115)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-178
 
-1.5 (+115)
O 9.5 (+100)
U 9.5 (-120)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+135
-160
+1.5 (-155)
-1.5 (+130)
O 8.5 (-105)
U 8.5 (-115)
Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
Nationals
+100
-120
+1.5 (-205)
-1.5 (+170)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+196
-240
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+130)
+1.5 (-155)
O 8 (-115)
U 8 (-105)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+110
-130
+1.5 (-190)
-1.5 (+158)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+175
-210
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+115
-135
+1.5 (-190)
-1.5 (+158)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+150
-178
+1.5 (-145)
-1.5 (+122)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+122
-145
+1.5 (-190)
-1.5 (+158)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+118
-140
+1.5 (-190)
-1.5 (+158)
O 7.5 (-115)
U 7.5 (-105)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-140
+118
-1.5 (+115)
+1.5 (-135)
O 9 (-110)
U 9 (-110)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+100
-120
+1.5 (-220)
-1.5 (+180)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
+1.5 (-195)
-1.5 (+162)
O 10 (-115)
U 10 (-105)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Chicago Cubs Cubs vs. Pittsburgh Pirates on April 30, 2025 at PNC Park.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS