Tigers vs Astros Prediction — AI Finds CAN'T MISS MLB Lines & Props (Apr 28)
Updated: 2025-04-26T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Detroit Tigers (17–10) visit the Houston Astros (13–13) on Monday, April 28, 2025, at Daikin Park in Houston, Texas. Both teams aim to gain momentum in the AL standings, with the Tigers seeking to extend their recent success and the Astros looking to capitalize on home-field advantage.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Apr 28, 2025
Start Time: 8:10 PM EST
Venue: Daikin Park
Astros Record: (14-13)
Tigers Record: (18-10)
OPENING ODDS
DET Moneyline: -113
HOU Moneyline: -106
DET Spread: -1.5
HOU Spread: +1.5
Over/Under: 8
DET
Betting Trends
- The Tigers have covered the run line in 6 of their last 7 games, indicating a strong performance against the spread (ATS).
HOU
Betting Trends
- The Astros are 5–1 ATS in their last 6 home games, showcasing strong performance against the spread.
MATCHUP TRENDS
- In their last 11 head-to-head matchups, the Tigers have covered the run line in 9 games against the Astros, suggesting a favorable trend for Detroit bettors.
DET vs. HOU
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: D. Dingler over 0.5 Total Bases.
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Detroit vs Houston Prediction & Odds:
Free MLB Betting Insights for 4/28/25
Houston’s offense remains as dangerous as ever, capable of putting up crooked numbers quickly when given even the slightest opportunity, while their pitching staff, though facing injuries, has begun to stabilize behind a mix of veteran arms and young talent eager to prove they belong. Historically, Detroit has found surprising success against Houston, covering the run line in nine of their last eleven head-to-head meetings, a trend that reflects the Tigers’ knack for playing competitive, grind-it-out baseball against elite opponents. Monday’s series opener will likely hinge on early momentum: if the Tigers can force Houston’s starters into deep counts and keep the game close into the late innings, their scrappy style could give them an edge; conversely, if the Astros’ powerful lineup finds its rhythm early, it could put too much pressure on a Detroit offense that, while improving, isn’t built to win high-scoring slugfests. For Houston, the formula will be to rely on their home-field energy, trust their high-leverage arms to preserve any leads, and continue to capitalize on scoring chances with runners in scoring position, where they have historically excelled. For Detroit, it will be about staying disciplined, maximizing every scoring opportunity, and showing the mental toughness that has quietly turned them into one of the more compelling surprise stories of the first month of the 2025 season. All signs point to a competitive, high-stakes series that could offer an early-season playoff atmosphere and valuable lessons for both clubs.
Skub Sunday 😮💨 pic.twitter.com/gjiuB1fjO2
— Detroit Tigers (@tigers) April 27, 2025
Detroit Tigers MLB Preview
The Detroit Tigers arrive at Daikin Park for Monday’s series opener against the Houston Astros with one of the most compelling early-season stories in Major League Baseball, boasting a 17–10 record that few outside their clubhouse likely saw coming and carrying a quiet but growing sense of belief that they can compete with the AL’s heavyweights. Under the steady hand of manager A.J. Hinch, the Tigers have crafted an identity built around gritty, fundamental baseball, using timely hitting, aggressive baserunning, and solid pitching to string together wins and stay near the top of the AL Central standings. Leading the offensive charge has been Zach McKinstry, whose versatility and clutch performances have helped anchor a lineup that has gotten contributions from up and down the order, while young players like Riley Greene and Kerry Carpenter have provided flashes of star potential, delivering big hits and keeping opposing pitchers honest with their ability to drive the ball to all fields. The Tigers’ pitching staff, though not overpowering, has embraced a next-man-up mentality, getting key innings from both starters and relievers who have shown a knack for battling through adversity and keeping games close even when facing lineups far more dangerous on paper.
Defensively, Detroit has been respectable, minimizing costly errors and showing improved communication and execution in critical moments, a testament to the emphasis Hinch has placed on winning the “small battles” that add up over the course of a season. Despite their relative youth, the Tigers have not shied away from challenges on the road, posting a strong 5–2 record away from Comerica Park and showing the kind of composure typically associated with more seasoned teams. Against an Astros team that remains one of baseball’s toughest opponents at home, the Tigers know they will need to stay patient at the plate, force Houston’s pitchers to work deep into counts, and capitalize on any mistakes, however rare, that the Astros allow. Having covered the run line in six of their last seven games and in nine of their last eleven meetings with Houston, Detroit has every reason to believe that if they stick to their formula of disciplined, opportunistic baseball, they can extend their early-season success and continue to surprise skeptics across the league. Monday’s game offers not just another chance to notch a win but a valuable test of how far this emerging Tigers team has come — and how far they might be able to go.

Credit: USA TODAY/IMAGN
Houston Astros MLB Preview
The Houston Astros return to Daikin Park for Monday’s series opener against the Detroit Tigers looking to continue building momentum after an up-and-down start to the 2025 campaign that sees them sitting at an even 13–13, striving to rediscover the form that has made them a perennial powerhouse over the past decade. Despite a few inconsistencies, particularly with their starting pitching due to early-season injuries, the Astros have remained formidable at home, posting a strong 5–1 ATS mark over their last six home games and steadily rounding into form both offensively and defensively. Leading the offensive charge is Yordan Alvarez, who continues to terrorize opposing pitchers with his combination of raw power, plate discipline, and ability to drive in runs in key situations, while Kyle Tucker has provided crucial balance from the other side of the plate with his all-around offensive excellence and baserunning prowess. Shortstop Jeremy Peña has been a steady force both defensively and with timely hits, while veterans like Alex Bregman and José Abreu have offered additional depth to a lineup that can beat opponents in a variety of ways, whether through big innings fueled by the long ball or by manufacturing runs through smart situational hitting.
On the mound, the Astros’ pitching staff has been resilient, with the bullpen in particular stepping up as a strength, anchored by closer Ryan Pressly and supported by Bryan Abreu and Rafael Montero, who have proven capable of preserving late leads against even the most dangerous lineups. Defensively, Houston remains one of the sharper teams in baseball, minimizing mistakes, turning double plays efficiently, and consistently providing their pitchers with strong support that can make the difference in close games. Manager Joe Espada has emphasized a return to fundamentals and relentless execution, understanding that winning series at home against competitive teams like Detroit is critical for keeping pace in what promises to be a tight AL West race. With the Tigers entering the series hot, the Astros know that applying early pressure, taking advantage of their power advantage at the plate, and keeping games from becoming late-inning battles will be essential if they want to assert control over the series. With their historical strength at home and a lineup beginning to fire on all cylinders, the Astros have a prime opportunity to send a message not just to Detroit but to the rest of the league that they remain a force to be reckoned with as the season moves into the summer months.
Big game from The Big Man. #BuiltForThis x @budweiserusa pic.twitter.com/9lQXSNM2qC
— Houston Astros (@astros) April 27, 2025
Detroit vs. Houston Prop Picks (AI)
Detroit vs. Houston Prediction (AI)

Remi, our AI sports genius, has been pouring over mountains of data from every angle between the Tigers and Astros and using recursive machine learning and impressive AI to examine the data to a single cover probability.
The Algorithm has been most keyed in on the linear correlation of weight emotional bettors regularly put on Houston’s strength factors between a Tigers team going up against a possibly strong Astros team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI Detroit vs Houston picks, computer picks Tigers vs Astros, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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ACTIVE PICKS LOCKED - SEE NOW |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Tigers Betting Trends
The Tigers have covered the run line in 6 of their last 7 games, indicating a strong performance against the spread (ATS).
Astros Betting Trends
The Astros are 5–1 ATS in their last 6 home games, showcasing strong performance against the spread.
Tigers vs. Astros Matchup Trends
In their last 11 head-to-head matchups, the Tigers have covered the run line in 9 games against the Astros, suggesting a favorable trend for Detroit bettors.
Detroit vs. Houston Game Info
What time does Detroit vs Houston start on April 28, 2025?
Detroit vs Houston starts on April 28, 2025 at 8:10 PM EST.
Where is Detroit vs Houston being played?
Venue: Daikin Park.
What are the opening odds for Detroit vs Houston?
Spread: Houston +1.5
Moneyline: Detroit -113, Houston -106
Over/Under: 8
What are the records for Detroit vs Houston?
Detroit: (18-10) | Houston: (14-13)
What is the AI best bet for Detroit vs Houston?
Remi's searched hard and found the best prop for this matchup: D. Dingler over 0.5 Total Bases.. Prices move—always shop for the best number.
What are Detroit vs Houston trending bets?
In their last 11 head-to-head matchups, the Tigers have covered the run line in 9 games against the Astros, suggesting a favorable trend for Detroit bettors.
What are Detroit trending bets?
DET trend: The Tigers have covered the run line in 6 of their last 7 games, indicating a strong performance against the spread (ATS).
What are Houston trending bets?
HOU trend: The Astros are 5–1 ATS in their last 6 home games, showcasing strong performance against the spread.
Where can I find AI Picks for Detroit vs Houston?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
Detroit vs. Houston Odds
Remi is pouring through tons of data on each team. In fact, anytime the Detroit vs Houston trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme temps rarely follow normal, predictable patterns.
Detroit vs Houston Opening Odds
DET Moneyline:
-113 HOU Moneyline: -106
DET Spread: -1.5
HOU Spread: +1.5
Over/Under: 8
Detroit vs Houston Live Odds
Games | PTS | ML | SPR | O/U | |
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Oct 19, 2025 8:04PM EDT
Seattle Mariners
Toronto Blue Jays
10/19/25 8:04PM
Mariners
Blue Jays
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–
–
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+108
-130
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+1.5 (-215)
-1.5 (+165)
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O 7.5 (-121)
U 7.5 (-106)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Detroit Tigers vs. Houston Astros on April 28, 2025 at Daikin Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
TOR@SEA | OVER 7 | 54.9% | 3 | WIN |
LAD@MIL | UNDER 7.5 | 56.6% | 6 | WIN |
TOR@NYY | OVER 8 | 54.9% | 4 | WIN |
TOR@NYY | CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED | 53.3% | 3 | WIN |
NYY@TOR | OVER 7.5 | 54.8% | 2 | WIN |
LAD@PHI | OVER 7 | 53.8% | 3 | WIN |
SD@CHC | CHC -109 | 53.8% | 3 | WIN |
SD@CHC | OVER 7.5 | 54.5% | 4 | LOSS |
SD@CHC | CHC -111 | 54.8% | 4 | LOSS |
CIN@LAD | SHOHEI OHTANI OVER 1.5 BASES | 53.5% | 3 | WIN |
BOS@NYY | OVER 7 | 53.8% | 3 | LOSS |
CIN@LAD | ELLY DE LA CRUZ OVER 0.5 BASES | 54.4% | 4 | LOSS |
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |