Phillies vs Cubs Prediction — AI Finds CAN'T MISS MLB Lines & Props (Apr 27)

Updated: 2025-04-25T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Philadelphia Phillies (14–13) and Chicago Cubs (17–11) will face off in the rubber match of their three-game series at Wrigley Field on Sunday, April 27, 2025, with first pitch scheduled for 6:10 PM CT. Both teams have split the first two games, and this nationally televised ESPN matchup features a pitching duel between Phillies ace Aaron Nola and Cubs veteran Jameson Taillon.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 27, 2025

Start Time: 7:10 PM EST​

Venue: Wrigley Field​

Cubs Record: (17-11)

Phillies Record: (14-13)

OPENING ODDS

PHI Moneyline: -114

CHC Moneyline: -105

PHI Spread: -1.5

CHC Spread: +1.5

Over/Under: 8

PHI
Betting Trends

  • The Phillies have struggled against the spread (ATS) on the road this season, holding a 5–9 ATS record in away games.

CHC
Betting Trends

  • The Cubs have been solid at home, posting a 7–6 ATS record in their last 13 home games.

MATCHUP TRENDS

  • The Cubs are 8–2 straight up after a loss this season, indicating a strong bounce-back ability.

PHI vs. CHC
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: I. Happ over 0.5 Total Bases.

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Philadelphia vs Chicago Cubs Prediction & Odds:
Free MLB Betting Insights for 4/27/25

The Philadelphia Phillies and Chicago Cubs meet Sunday night at Wrigley Field in the rubber match of a competitive three-game set, with both teams eager to grab momentum as the calendar prepares to turn to May. Philadelphia, sitting at 14–13, bounced back after a rough stretch to split the first two games of the series, and they will send Aaron Nola to the mound, desperately seeking a return to form after an 0–5 start with a bloated 6.43 ERA. Nola, once one of the Phillies’ most reliable arms, has struggled with command and home-run prevention, and Sunday’s nationally televised start offers an opportunity for redemption against a potent Cubs lineup. Chicago, boasting a strong 17–11 record and one of the National League’s most dynamic offenses, will counter with veteran Jameson Taillon, who enters with a 1–1 record and a 4.73 ERA, providing steady innings for a team that has thrived by scoring early and often at home. Offensively, the Cubs have been anchored by Nico Hoerner, batting .324 and consistently setting the table for power threats like Kyle Tucker, who has already launched seven home runs while driving in 21 runs, making him one of the Cubs’ most dangerous bats. The Phillies counter with their own firepower, as Nick Castellanos continues to swing a hot bat at .319, while Kyle Schwarber, a former Cubs fan favorite, brings his home-run pop and familiarity with Wrigley’s dimensions into the heart of Philadelphia’s order.

Recent trends suggest a tightly contested battle: the Cubs have been impressive at home, posting a 7–6 ATS record in their last 13 games at Wrigley, and more importantly, they are 8–2 straight up following a loss this season, indicating a strong ability to bounce back after setbacks. The Phillies, on the other hand, have struggled on the road, with a 5–9 ATS record away from Citizens Bank Park, although recent signs of life offensively give them reasons for optimism. Defensively, both clubs have been sound, but Philadelphia’s bullpen has been more vulnerable, often placing additional pressure on their starters to work deeper into games. For the Cubs, the game plan will likely focus on applying early pressure to Nola, forcing him into high-stress innings, and handing a lead to their bullpen, which has been more effective at home. For the Phillies, it will be critical for Nola to set the tone early, avoid the big inning, and give his offense a chance to build a lead against Taillon before the back end of the Cubs’ bullpen tightens the screws. With both teams featuring capable lineups and starting pitchers looking to prove something, Sunday’s matchup promises to be a spirited, high-energy contest at one of baseball’s most iconic ballparks, where the smallest mistake—or the biggest swing—could very well determine who leaves Wrigley Field victorious.

Philadelphia Phillies MLB Preview

The Philadelphia Phillies step onto the field at Wrigley on Sunday night with an opportunity to cap off an important series win, seeking consistency after a 14–13 start to a season that has been marked by flashes of brilliance mixed with frustrating inconsistency. The Phillies will once again turn to Aaron Nola, who despite his past reputation as one of the staff’s anchors, enters the game still searching for his first victory of 2025, saddled with an 0–5 record and a 6.43 ERA that reflect ongoing struggles with fastball command and an inability to escape big innings. Philadelphia’s offense, however, has been showing encouraging signs of life, led by Nick Castellanos’ .319 batting average and the ever-dangerous Kyle Schwarber, who has blasted seven home runs while driving in 15 runs, providing much-needed power from the heart of the lineup. Key contributions from Alec Bohm and Bryson Stott have added some balance to the order, but the Phillies know that scoring consistently on the road against a Cubs team that thrives at home will require disciplined at-bats and better execution with runners in scoring position.

Defensively, the Phillies have been solid, but bullpen volatility remains a concern, often forcing the offense to play catch-up late in games when early leads slip away. Manager Rob Thomson has placed an increased emphasis on getting back to basics—pitching to contact, minimizing walks, and making the routine plays defensively—to help stabilize the club and capitalize on their considerable offensive potential. For Philadelphia, the path to victory Sunday hinges largely on Nola rediscovering his form and giving the bullpen a smaller margin of error to work with, while the offense must continue to apply pressure early to avoid chasing late against a savvy Cubs relief corps. A victory under the lights at Wrigley Field would not only secure an important series win against a division-leading opponent but also provide the kind of spark that could fuel a more sustained push up the standings as the Phillies work to establish themselves as serious contenders once again.

The Philadelphia Phillies (14–13) and Chicago Cubs (17–11) will face off in the rubber match of their three-game series at Wrigley Field on Sunday, April 27, 2025, with first pitch scheduled for 6:10 PM CT. Both teams have split the first two games, and this nationally televised ESPN matchup features a pitching duel between Phillies ace Aaron Nola and Cubs veteran Jameson Taillon. Philadelphia vs Chicago Cubs AI Prediction: Free MLB Betting Insights for Apr 27. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Chicago Cubs Cubs MLB Preview

The Chicago Cubs enter Sunday’s showdown at Wrigley Field determined to bounce back and take the series after a setback in Game 2, leaning on a strong overall 17–11 record and the confidence that comes from playing some of the best baseball in the National League over the past few weeks. The Cubs have been particularly dangerous at home, where their offense has flourished, averaging over six runs per game while blending speed, power, and patient at-bats to pressure opposing pitchers from the outset. Jameson Taillon gets the nod for Chicago, tasked with setting a steady tone after posting a 1–1 record and a 4.73 ERA through his early-season outings, relying on a mix of cutters, sinkers, and occasional breaking balls to generate weak contact and navigate deeper into games. Offensively, the Cubs continue to ride the red-hot bat of Nico Hoerner, who enters Sunday’s game batting .324, providing exceptional on-base skills and timely hits, while Kyle Tucker’s presence in the middle of the lineup, with seven home runs and 21 RBIs already, adds the kind of thump that can change a game with one swing.

The Cubs’ defensive efficiency has also played a major role in their early success, with strong infield play and reliable outfield defense helping to limit mistakes and support a bullpen that has found its rhythm at home. Manager Craig Counsell has emphasized the importance of resilience, and his squad has responded, going 8–2 straight up following a loss this season, a testament to the culture of focus and competitiveness he has cultivated. For Chicago, the formula for Sunday is clear: get Taillon early run support, use aggressive baserunning to pressure the Phillies’ defense, and trust the bullpen to lock down a lead in the late innings. With a chance to close out the series with a statement victory in front of a raucous home crowd, the Cubs will look to impose their will early and continue their climb up the National League standings with a performance that highlights their balance, depth, and hunger to contend deep into the season.

Philadelphia vs. Chicago Cubs Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each player. In fact, anytime the Phillies and Cubs play there’s always several intriguing angles to key in on. Not to mention games played at Wrigley Field in Apr almost always follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: I. Happ over 0.5 Total Bases.

Philadelphia vs. Chicago Cubs Prediction (AI)

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Remi, our AI sports genius, has been pouring over mountains of data from every angle between the Phillies and Cubs and using recursive machine learning and kick-ass AI to examine the data to a single cover probability.

Remi has been most focused on the growing factor emotional bettors regularly put on player performance factors between a Phillies team going up against a possibly improved Cubs team. In reality, the true game analytics might reflect a slight lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Philadelphia vs Chicago Cubs picks, computer picks Phillies vs Cubs, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Phillies Betting Trends

The Phillies have struggled against the spread (ATS) on the road this season, holding a 5–9 ATS record in away games.

Cubs Betting Trends

The Cubs have been solid at home, posting a 7–6 ATS record in their last 13 home games.

Phillies vs. Cubs Matchup Trends

The Cubs are 8–2 straight up after a loss this season, indicating a strong bounce-back ability.

Philadelphia vs. Chicago Cubs Game Info

Philadelphia vs Chicago Cubs starts on April 27, 2025 at 7:10 PM EST.

Spread: Chicago Cubs +1.5
Moneyline: Philadelphia -114, Chicago Cubs -105
Over/Under: 8

Philadelphia: (14-13)  |  Chicago Cubs: (17-11)

Remi's searched hard and found the best prop for this matchup: I. Happ over 0.5 Total Bases.. Prices move—always shop for the best number.

The Cubs are 8–2 straight up after a loss this season, indicating a strong bounce-back ability.

PHI trend: The Phillies have struggled against the spread (ATS) on the road this season, holding a 5–9 ATS record in away games.

CHC trend: The Cubs have been solid at home, posting a 7–6 ATS record in their last 13 home games.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Philadelphia vs. Chicago Cubs Odds

AI algorithm Remi is pouring through tons of data points on each team. In fact, anytime the Philadelphia vs Chicago Cubs trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable patterns.

Philadelphia vs Chicago Cubs Opening Odds

PHI Moneyline: -114
CHC Moneyline: -105
PHI Spread: -1.5
CHC Spread: +1.5
Over/Under: 8

Philadelphia vs Chicago Cubs Live Odds

Games PTS ML SPR O/U

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Philadelphia Phillies vs. Chicago Cubs Cubs on April 27, 2025 at Wrigley Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
LAD@TOR TOR +1.5 56.7% 2 WIN
TOR@LAD TOR +1.5 55.3% 4 WIN
TOR@SEA OVER 7 54.9% 3 WIN
LAD@MIL UNDER 7.5 56.6% 6 WIN
TOR@NYY OVER 8 54.9% 4 WIN
TOR@NYY CARLOS RODON OVER 1.5 TOTAL WALKS ALLOWED 53.3% 3 WIN
NYY@TOR OVER 7.5 54.8% 2 WIN
LAD@PHI OVER 7 53.8% 3 WIN
SD@CHC CHC -109 53.8% 3 WIN
SD@CHC OVER 7.5 54.5% 4 LOSS
SD@CHC CHC -111 54.8% 4 LOSS
CIN@LAD SHOHEI OHTANI OVER 1.5 BASES 53.5% 3 WIN
BOS@NYY OVER 7 53.8% 3 LOSS
CIN@LAD ELLY DE LA CRUZ OVER 0.5 BASES 54.4% 4 LOSS
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN