Tigers vs. Brewers
Prediction, Odds & Props
Apr 16 | MLB AI Picks

Updated: 2025-04-14T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On April 16, 2025, the Detroit Tigers (10–7) will face the Milwaukee Brewers (9–9) at American Family Field. Both teams aim to secure the series win in this rubber match, with the Tigers seeking to build on their recent momentum and the Brewers looking to rebound from a three-game losing streak.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Apr 16, 2025

Start Time: 1:10 PM EST​

Venue: American Family Field​

Brewers Record: (9-9)

Tigers Record: (10-7)

OPENING ODDS

DET Moneyline: +120

MIL Moneyline: -142

DET Spread: +1.5

MIL Spread: -1.5

Over/Under: 8

DET
Betting Trends

  • The Tigers have a 5–5 record against the spread (ATS) in road games this season.

MIL
Betting Trends

  • The Brewers hold a 6–3 ATS record at home, indicating strong performances at American Family Field.

MATCHUP TRENDS

  • The Tigers have covered the spread in three of their last five games, showcasing their competitive edge in recent matchups.

DET vs. MIL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: S. Torkelson over 5.5 Fantasy Score.

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Detroit vs Milwaukee Prediction & Odds:
Free MLB Betting Insights for 4/16/25

Wednesday’s series finale between the Detroit Tigers and the Milwaukee Brewers at American Family Field offers a compelling rubber match between two teams trying to assert early season consistency. The Tigers arrive with a 10–7 record and atop the AL Central, bolstered by a balanced combination of offensive execution and competent pitching. Their lineup has been sparked by the production of Riley Greene, who leads the club with three home runs, and catcher Dillon Dingler, who is hitting .400 and delivering clutch RBIs in key situations. Detroit’s offense ranks among the better in the league in batting average (.269) and on-base percentage (.357), numbers that have fueled their recent momentum. While their team ERA of 4.26 is middle-of-the-pack, their WHIP of 1.088 suggests they’ve done well in limiting baserunners and preventing innings from unraveling. On the mound, the Tigers will turn to Keider Montero, a right-hander recently recalled from Triple-A who dominated his last outing with 5 2⁄3 perfect innings and six strikeouts. He’ll be tested by a Brewers lineup that has been streaky but features established threats like Christian Yelich and William Contreras. Milwaukee enters the game with a 9–9 record and a 6–3 home mark, showing they are generally tough to beat at American Family Field. However, they are currently riding a three-game losing streak, which has placed pressure on the lineup to offer better run support to a pitching staff that’s done its part.

Veteran left-hander José Quintana, who takes the mound for the Brewers, has been flawless so far this season with a 0.00 ERA and the ability to change speeds effectively to disrupt timing. Quintana’s presence gives Milwaukee a reliable arm to potentially steady the ship and snap their losing skid. As both teams split the first two games of the series, the winner of this game not only takes the set but also gains a critical morale boost. The Tigers aim to prove they can be a serious early-season contender, especially on the road, while the Brewers are focused on reestablishing their dominance at home and regaining momentum in a competitive NL Central. Statistically, Detroit has been more productive at the plate, while Milwaukee holds the edge in overall pitching numbers, setting the stage for a well-matched battle. Betting-wise, the Tigers have gone 5–5 ATS on the road, while the Brewers have been stronger at home with a 6–3 ATS record, suggesting a slight edge to Milwaukee if they can control the tempo and keep Detroit’s bats quiet. The key factor may be which starting pitcher settles in quicker—Montero with his electric stuff and youthful confidence, or Quintana with veteran savvy and command. With both lineups capable of generating runs and both bullpens having shown flashes of strength, this matchup could come down to late-inning execution, timely hits, and a single mistake proving costly. It’s the kind of game that tests focus, depth, and resilience—and the winner may well ride that momentum into the next phase of the season with a clearer identity and increased confidence.

Detroit Tigers MLB Preview

The Detroit Tigers enter Wednesday’s series finale against the Milwaukee Brewers with quiet confidence and a firm grip on the AL Central lead, sitting at 10–7 after a surprisingly consistent and disciplined start to their 2025 campaign. Detroit has demonstrated a balanced brand of baseball, underpinned by a solid offensive approach and emerging pitching talent, and this matchup marks a significant opportunity for the Tigers to claim a quality road series win against a perennial NL playoff contender. Offensively, the Tigers have been clicking with a .269 team batting average and a .357 OBP, led by breakout contributors like Dillon Dingler—who boasts a .400 average and six RBIs—and Riley Greene, who leads the club with three home runs and continues to demonstrate growth as a power bat and clubhouse leader. The batting order is showing excellent plate discipline, and their run production has allowed them to apply pressure early and hold leads late, a development that reflects a maturing and evolving offensive identity. On the mound, Detroit will hand the ball to 23-year-old right-hander Keider Montero, recently recalled from Triple-A after a dominant stretch that included 5 2⁄3 perfect innings and six strikeouts in his most recent outing. Montero brings electric stuff and developing command, and the Tigers are hoping he can translate his minor league dominance into a quality start at the major league level. The pitching staff overall has maintained a collective 4.26 ERA and a 1.088 WHIP, illustrating their ability to limit damage and strand runners.

That said, facing a team like Milwaukee—known for its opportunistic offense and patient plate approach—will be a real test for Montero, especially given the Brewers’ track record at home. Defensively, Detroit has supported its pitchers well, avoiding costly errors and executing double plays effectively, and that clean play will need to continue against a Brewers lineup capable of capitalizing on lapses. This game carries significant importance for Detroit not only in the standings but in continuing to build internal belief and rhythm heading into tougher stretches of the season. A road win against a capable club like Milwaukee, especially with a young starter on the bump, would serve as a strong proof point for a team that is trying to prove its staying power as more than just an early-season surprise. For the Tigers, it’s about consistency, executing the fundamentals, and giving Montero the confidence to attack the zone and trust the defense behind him. With momentum on their side and a roster beginning to gel across all phases, the Tigers will look to punctuate the series with a complete team effort that reinforces their legitimacy as a true contender in the AL Central.

On April 16, 2025, the Detroit Tigers (10–7) will face the Milwaukee Brewers (9–9) at American Family Field. Both teams aim to secure the series win in this rubber match, with the Tigers seeking to build on their recent momentum and the Brewers looking to rebound from a three-game losing streak. Detroit vs Milwaukee AI Prediction: Free MLB Betting Insights for Apr 16. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Milwaukee Brewers MLB Preview

The Milwaukee Brewers return to American Family Field for the final game of a three-game set against the Detroit Tigers, looking to close the series strong and snap a recent three-game losing skid. With a 9–9 overall record and a solid 6–3 mark at home, the Brewers have demonstrated an early-season ability to protect their turf and lean on consistent pitching to stay competitive. José Quintana, who takes the mound for the finale, has yet to allow an earned run this season, and his veteran presence gives Milwaukee a clear strategic edge in tight contests. His command and ability to induce weak contact have been critical in helping the Brewers navigate a challenging schedule, and his leadership provides stability for a rotation that’s performed well collectively, entering the game with a team ERA of 3.60. While the Brewers’ offense has been up and down, there have been flashes of brilliance, with players like William Contreras delivering timely hits and Christian Yelich continuing to be a focal point of the lineup. However, run support remains a point of concern, especially in games that hinge on late-inning execution. Milwaukee’s bullpen has been generally reliable, allowing the club to maintain slim leads or stay within striking distance in low-scoring affairs, which has been their identity through the early part of the season.

On defense, the Brewers have been sharp and efficient, limiting errors and turning key double plays that often stall opposing rallies. Their solid defensive structure complements their pitching strengths, forming a winning formula—particularly in games played at home, where the energy of the crowd and familiarity with the field provide an extra edge. Facing a confident Tigers team that leads the AL Central, the Brewers know they must capitalize on every scoring opportunity, especially early in the game to give Quintana some breathing room and prevent the Tigers from dictating the tempo. To pull off the win, Milwaukee’s hitters must exhibit patience, particularly against Keider Montero, a young starter with strikeout potential but limited big-league exposure. If the Brewers can grind out at-bats and make Montero work deep into counts, they increase their chances of getting to Detroit’s bullpen earlier—a key factor in swinging the game in their favor. With playoff aspirations on the line this season, Milwaukee understands that these early-season series at home can have ripple effects later in the year, and they’ll be intent on delivering a crisp, disciplined performance to build positive momentum heading into their next stretch.

Detroit vs. Milwaukee Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each player. In fact, anytime the Tigers and Brewers play there’s always several intriguing observations to key in on. Not to mention games played at American Family Field in Apr seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: S. Torkelson over 5.5 Fantasy Score.

Detroit vs. Milwaukee Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over millions of data from every facet between the Tigers and Brewers and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most watching on the linear correlation of factor emotional bettors regularly put on player performance factors between a Tigers team going up against a possibly deflated Brewers team. It appears the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Detroit vs Milwaukee picks, computer picks Tigers vs Brewers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
MLB 9/26 DET@BOS UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
MLB 9/26 BAL@NYY UNLOCK THIS PICK 4 INTEL Locked INTEL
MLB 9/26 ARI@SD UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE
MLB 9/26 NYM@MIA UNLOCK THIS PICK 1 INTEL Locked INTEL
MLB 9/26 NYM@MIA GET FREE PICK NOW 1
MLB 9/26 COL@SF UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Tigers Betting Trends

The Tigers have a 5–5 record against the spread (ATS) in road games this season.

Brewers Betting Trends

The Brewers hold a 6–3 ATS record at home, indicating strong performances at American Family Field.

Tigers vs. Brewers Matchup Trends

The Tigers have covered the spread in three of their last five games, showcasing their competitive edge in recent matchups.

Detroit vs. Milwaukee Game Info

Detroit vs Milwaukee starts on April 16, 2025 at 1:10 PM EST.

Venue: American Family Field.

Spread: Milwaukee -1.5
Moneyline: Detroit +120, Milwaukee -142
Over/Under: 8

Detroit: (10-7)  |  Milwaukee: (9-9)

Remi's searched hard and found the best prop for this matchup: S. Torkelson over 5.5 Fantasy Score.. Prices move—always shop for the best number.

The Tigers have covered the spread in three of their last five games, showcasing their competitive edge in recent matchups.

DET trend: The Tigers have a 5–5 record against the spread (ATS) in road games this season.

MIL trend: The Brewers hold a 6–3 ATS record at home, indicating strong performances at American Family Field.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Detroit vs. Milwaukee Odds

Remi is pouring through mountains of data on each player. In fact, anytime the Detroit vs Milwaukee trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable patterns.

Detroit vs Milwaukee Opening Odds

DET Moneyline: +120
MIL Moneyline: -142
DET Spread: +1.5
MIL Spread: -1.5
Over/Under: 8

Detroit vs Milwaukee Live Odds

Games PTS ML SPR O/U
Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
+190
-235
+1.5 (-110)
-1.5 (-110)
O 8.5 (-120)
U 8.5 (+100)
Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
 
-180
 
-1.5 (+115)
O 9.5 (-105)
U 9.5 (-115)
Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
+130
-155
+1.5 (-155)
-1.5 (+130)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:06PM
White Sox
Nationals
+100
-120
-1.5 (+165)
+1.5 (-200)
O 8.5 (-110)
U 8.5 (-110)
Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
+185
-225
+1.5 (-110)
-1.5 (-110)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
-130
+110
-1.5 (+125)
+1.5 (-150)
O 8 (-115)
U 8 (-105)
Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
+125
-150
+1.5 (-180)
-1.5 (+150)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
+170
-205
+1.5 (-120)
-1.5 (+100)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
+125
-150
+1.5 (-180)
-1.5 (+150)
O 8 (-105)
U 8 (-115)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+145
-175
+1.5 (-155)
-1.5 (+130)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+135
-165
+1.5 (-180)
-1.5 (+150)
O 7 (-120)
U 7 (+100)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
+115
-140
+1.5 (-195)
-1.5 (+160)
O 7.5 (-120)
U 7.5 (+100)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
-165
+135
-1.5 (+105)
+1.5 (-125)
O 9 (+100)
U 9 (-120)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
+105
-125
+1.5 (-205)
-1.5 (+170)
O 7.5 (+105)
U 7.5 (-125)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
+100
-120
-1.5 (+150)
+1.5 (-180)
O 10 (-110)
U 10 (-110)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Detroit Tigers vs. Milwaukee Brewers on April 16, 2025 at American Family Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS
CIN@ARI KEBRYAN HAYES STRIKEOUTS UNDER 0.5 56.2% 6 WIN
LAD@SD SD +110 50.9% 6 WIN