Padres vs. Athletics
Prediction, Odds & Props
Apr 07 | MLB AI Picks
Updated: 2025-04-05T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The San Diego Padres are set to face the Athletics on April 7, 2025, at Sutter Health Park in Sacramento, California. This interleague matchup features two teams with contrasting early-season performances.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Apr 07, 2025
Start Time: 10:05 PM EST
Venue: Sutter Health Park
Athletics Record: (4-6)
Padres Record: (8-2)
OPENING ODDS
SD Moneyline: -144
ATH Moneyline: +121
SD Spread: -1.5
ATH Spread: +1.5
Over/Under: 8.5
SD
Betting Trends
- As of April 4, 2025, the Padres have an impressive 7-0 record against the spread (ATS), demonstrating their strong performance both straight-up and in covering the run line.
ATH
Betting Trends
- As of April 2, 2025, the Athletics have a 2-4 record. Their ATS performance has been inconsistent, reflecting the team’s struggles in the early part of the season.
MATCHUP TRENDS
- The Padres’ flawless ATS record indicates their ability to not only secure victories but also exceed expectations in terms of run margins. Conversely, the Athletics’ subpar start suggests potential challenges in covering spreads, especially against high-performing teams like the Padres.
SD vs. ATH
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: T. Soderstrom over 0.5 Hits+Runs+RBI.
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San Diego vs Athletics Prediction & Odds:
Free MLB Betting Insights for 4/7/25
Defensively, miscues and communication lapses have led to unearned runs that swing games out of reach early. Compounding their issues, the Athletics’ bullpen has been stretched thin due to short outings from starters, exposing the depth gap between them and a Padres club built to contend. From a betting perspective, the discrepancy is even more pronounced—San Diego has covered every spread so far this season, showing their ability to exceed expectations, while Oakland has only managed to cover twice, often falling behind early and struggling to claw back into games. With the Padres’ confidence at a season-high and their roster depth allowing for strategic flexibility, this game presents a significant challenge for the Athletics, even with home-field advantage in Sacramento. For Oakland to stay competitive, they’ll need a near-perfect outing from their starting pitcher, clean defensive play, and opportunistic offense against one of the most complete teams in baseball. San Diego, on the other hand, will look to extend their winning streak by staying aggressive, capitalizing on Oakland’s weaknesses, and continuing to play fundamentally sound baseball. Unless the Athletics can deliver their sharpest all-around performance of the season, the Padres are well-positioned to control the pace, dictate the scoreboard, and add yet another tally to their undefeated start.
Fly the W! pic.twitter.com/WPe2A90TTn
— San Diego Padres (@Padres) April 6, 2025
San Diego Padres MLB Preview
The San Diego Padres enter their April 7, 2025 matchup against the Athletics with supreme confidence and early-season momentum, boasting an undefeated 7-0 record and an equally flawless 7-0 mark against the spread. This dominant start is a testament to the Padres’ complete team construction, where elite offensive firepower, precision pitching, and airtight defense have converged to create one of the most formidable lineups in baseball. The offense is paced by a core of stars including Fernando Tatís Jr., Manny Machado, and Xander Bogaerts, each of whom has contributed in high-leverage moments, whether by delivering clutch extra-base hits or setting the tone early in games. The lineup’s depth makes it difficult for opposing pitchers to find any breathing room, with even the bottom third of the order generating traffic and capitalizing on RBI opportunities. The Padres have excelled at turning small advantages into big innings, a key factor in their ability to cover the run line with ease. On the mound, the rotation has provided stability and dominance, led by veterans who are not only eating innings but doing so efficiently.
Their bullpen has been sharp and reliable, consistently protecting leads and closing out games without unnecessary drama. The Padres’ pitching staff has done an excellent job of limiting damage, rarely giving up big innings, and their starters have often gone deep enough to give the bullpen rest—a critical advantage in a long season. On the defensive side, San Diego has been clean, poised, and opportunistic, avoiding costly errors and turning double plays with precision. Against an Athletics team that has struggled to string together runs and shows vulnerability in late-inning situations, the Padres are positioned to control this game from the opening pitch. From a strategic standpoint, San Diego’s aggressive baserunning and pitch discipline have been equally important, keeping constant pressure on opposing pitchers and fielders. This matchup provides the Padres a chance to extend their perfect run and reinforce their status as one of the most balanced and dangerous teams in the league. The key will be to maintain their focus and not allow complacency to creep in against an opponent that, while struggling, will be eager to steal a win on home turf. As long as the Padres stick to the formula that’s brought them early success—strong starting pitching, opportunistic offense, and mistake-free defense—they’ll be well-positioned to continue their flawless start and keep stacking wins as they push forward in the NL West race.

Credit: USA TODAY/IMAGN
Athletics Athletics MLB Preview
The Athletics return home to Sutter Health Park on April 7, 2025, facing a daunting challenge against the undefeated San Diego Padres and hoping to find a spark that can lift them out of a frustrating 2-4 start. The early part of the season has exposed several critical issues for the A’s, beginning with a lineup that has struggled to generate runs consistently, often falling behind early and lacking the firepower or plate discipline to mount comebacks. While young talents like Brent Rooker and Esteury Ruiz have offered flashes of promise, the offense as a whole has lacked cohesion, leaving runners stranded and failing to convert on scoring opportunities. This lack of run support has only magnified the pressure on a pitching staff that’s already been stretched thin. Starters have rarely been able to go deep into games, placing significant stress on a bullpen that has been overexposed and largely ineffective in preserving leads or keeping deficits manageable. Defensively, the A’s have not helped their own cause either, with miscues and lapses in situational awareness leading to unearned runs and extended innings for opposing teams. These struggles have translated directly to poor performance against the spread, as Oakland has covered in just two of its first six games, unable to keep games close against better-prepared and better-executing opponents. Entering this matchup, the key for the Athletics will be to play fundamentally clean baseball—minimizing errors, throwing strikes, and being aggressive but smart at the plate.
Their best chance to compete lies in finding early offensive rhythm and forcing the Padres to play from behind—something no team has managed to do yet this season. A standout performance from their starting pitcher would be essential, ideally going five or more innings to keep the bullpen fresh and avoid the late-game breakdowns that have cost them dearly in past outings. Playing at home could provide a morale boost, especially with the Sacramento crowd looking for something to rally behind, but the A’s will need to back that energy up with crisp execution and urgency from the first pitch. Facing a team as well-rounded as the Padres demands near-flawless play, and for a young, rebuilding roster like the Athletics, that means seizing every opportunity and not allowing innings to spiral out of control. A win in this matchup wouldn’t just snap the Padres’ unbeaten run—it would provide a much-needed jolt of confidence to a team still searching for its identity and rhythm in 2025. With a clean, competitive showing, the Athletics could start turning the page on a difficult start and begin building toward the long-term development goals that are critical to the franchise’s growth.
Law Dawg has arrived 😤 pic.twitter.com/jnlaBNeFor
— Athletics (@Athletics) April 6, 2025
San Diego vs. Athletics Prop Picks (AI)
San Diego vs. Athletics Prediction (AI)

Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every angle between the Padres and Athletics and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.
The Algorithm has been most focused on the unproportionally assigned weight human bettors often put on Athletics’s strength factors between a Padres team going up against a possibly healthy Athletics team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.
Below is our current AI San Diego vs Athletics picks, computer picks Padres vs Athletics, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.
Padres Betting Trends
As of April 4, 2025, the Padres have an impressive 7-0 record against the spread (ATS), demonstrating their strong performance both straight-up and in covering the run line.
Athletics Betting Trends
As of April 2, 2025, the Athletics have a 2-4 record. Their ATS performance has been inconsistent, reflecting the team’s struggles in the early part of the season.
Padres vs. Athletics Matchup Trends
The Padres’ flawless ATS record indicates their ability to not only secure victories but also exceed expectations in terms of run margins. Conversely, the Athletics’ subpar start suggests potential challenges in covering spreads, especially against high-performing teams like the Padres.
San Diego vs. Athletics Game Info
What time does San Diego vs Athletics start on April 07, 2025?
San Diego vs Athletics starts on April 07, 2025 at 10:05 PM EST.
Where is San Diego vs Athletics being played?
Venue: Sutter Health Park.
What are the opening odds for San Diego vs Athletics?
Spread: Athletics +1.5
Moneyline: San Diego -144, Athletics +121
Over/Under: 8.5
What are the records for San Diego vs Athletics?
San Diego: (8-2) | Athletics: (4-6)
What is the AI best bet for San Diego vs Athletics?
Remi's searched hard and found the best prop for this matchup: T. Soderstrom over 0.5 Hits+Runs+RBI.. Prices move—always shop for the best number.
What are San Diego vs Athletics trending bets?
The Padres’ flawless ATS record indicates their ability to not only secure victories but also exceed expectations in terms of run margins. Conversely, the Athletics’ subpar start suggests potential challenges in covering spreads, especially against high-performing teams like the Padres.
What are San Diego trending bets?
SD trend: As of April 4, 2025, the Padres have an impressive 7-0 record against the spread (ATS), demonstrating their strong performance both straight-up and in covering the run line.
What are Athletics trending bets?
ATH trend: As of April 2, 2025, the Athletics have a 2-4 record. Their ATS performance has been inconsistent, reflecting the team’s struggles in the early part of the season.
Where can I find AI Picks for San Diego vs Athletics?
See our latest MLB picks and odds pages for 2025 to compare prices before you bet.
San Diego vs. Athletics Odds
Remi is pouring through tons of data points on each line. In fact, anytime the San Diego vs Athletics trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude seemingly never follow normal, predictable patterns.
San Diego vs Athletics Opening Odds
SD Moneyline:
-144 ATH Moneyline: +121
SD Spread: -1.5
ATH Spread: +1.5
Over/Under: 8.5
San Diego vs Athletics Live Odds
Games | PTS | ML | SPR | O/U | |
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Sep 27, 2025 1:06PM EDT
Baltimore Orioles
New York Yankees
9/27/25 1:06PM
Orioles
Yankees
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–
–
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+196
-240
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+1.5 (-105)
-1.5 (-115)
|
O 9 (-105)
U 9 (-115)
|
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Sep 27, 2025 2:21PM EDT
St Louis Cardinals
Chicago Cubs
9/27/25 2:21PM
Cardinals
Cubs
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–
–
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-178
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-1.5 (+115)
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O 9.5 (+100)
U 9.5 (-120)
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Sep 27, 2025 3:09PM EDT
Tampa Bay Rays
Toronto Blue Jays
9/27/25 3:09PM
Rays
Blue Jays
|
–
–
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+135
-160
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+1.5 (-155)
-1.5 (+130)
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O 8.5 (-105)
U 8.5 (-115)
|
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Sep 27, 2025 4:05PM EDT
Chicago White Sox
Washington Nationals
9/27/25 4:05PM
White Sox
Nationals
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–
–
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+100
-120
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+1.5 (-205)
-1.5 (+170)
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O 8.5 (-115)
U 8.5 (-105)
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Sep 27, 2025 4:06PM EDT
Colorado Rockies
San Francisco Giants
9/27/25 4:06PM
Rockies
Giants
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–
–
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+196
-240
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+1.5 (-110)
-1.5 (-110)
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O 8 (-105)
U 8 (-115)
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Sep 27, 2025 4:11PM EDT
New York Mets
Miami Marlins
9/27/25 4:11PM
Mets
Marlins
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–
–
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-130
+110
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-1.5 (+130)
+1.5 (-155)
|
O 8 (-115)
U 8 (-105)
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Sep 27, 2025 4:11PM EDT
Detroit Tigers
Boston Red Sox
9/27/25 4:11PM
Tigers
Red Sox
|
–
–
|
+110
-130
|
+1.5 (-190)
-1.5 (+158)
|
O 9 (+100)
U 9 (-120)
|
|
Sep 27, 2025 6:05PM EDT
Minnesota Twins
Philadelphia Phillies
9/27/25 6:05PM
Twins
Phillies
|
–
–
|
+175
-210
|
+1.5 (-120)
-1.5 (+100)
|
O 8.5 (-115)
U 8.5 (-105)
|
|
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
Reds
Brewers
|
–
–
|
+115
-135
|
+1.5 (-190)
-1.5 (+158)
|
O 7.5 (-120)
U 7.5 (+100)
|
|
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
|
–
–
|
+150
-178
|
+1.5 (-145)
-1.5 (+122)
|
O 8 (-110)
U 8 (-110)
|
|
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
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–
–
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+122
-145
|
+1.5 (-190)
-1.5 (+158)
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O 7 (-120)
U 7 (+100)
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Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
Padres
|
–
–
|
+118
-140
|
+1.5 (-190)
-1.5 (+158)
|
O 7.5 (-115)
U 7.5 (-105)
|
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Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
Angels
|
–
–
|
-140
+118
|
-1.5 (+115)
+1.5 (-135)
|
O 9 (-110)
U 9 (-110)
|
|
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
Dodgers
Mariners
|
–
–
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+100
-120
|
+1.5 (-220)
-1.5 (+180)
|
O 7 (-120)
U 7 (+100)
|
|
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
Royals
Athletics
|
–
–
|
+100
-120
|
+1.5 (-195)
-1.5 (+162)
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O 10 (-115)
U 10 (-105)
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MLB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers San Diego Padres vs. Athletics Athletics on April 07, 2025 at Sutter Health Park.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
ARI@SD | SD -131 | 57.3% | 4 | WIN |
DET@BOS | BOS -115 | 56.4% | 5 | WIN |
NYM@CHC | NYM -110 | 54.1% | 3 | WIN |
HOU@ATH | ATH +118 | 50.8% | 4 | WIN |
NYM@CHC | OVER 7 | 54.5% | 3 | WIN |
STL@SF | OVER 7.5 | 55.9% | 5 | LOSS |
KC@LAA | TYLER TOLBERT UNDER 1.5 BASES | 54.4% | 4 | WIN |
MIL@SD | UNDER 9 | 54.7% | 4 | WIN |
MIA@PHI | KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS | 53.3% | 3 | WIN |
WAS@NYM | OVER 8.5 | 56.1% | 6 | LOSS |
LAA@COL | COL +108 | 50.5% | 3 | WIN |
TOR@KC | UNDER 9 | 54.7% | 4 | LOSS |
SEA@KC | KC +1.5 | 62.3% | 5 | LOSS |
NYY@MIN | OVER 9 | 55.1% | 4 | WIN |
MIA@COL | OVER 10.5 | 55.0% | 4 | WIN |
MIA@COL | AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS | 54.3% | 4 | WIN |
SEA@KC | BOBBY WITT UNDER 0.5 SINGLES | 54.4% | 4 | LOSS |
PHI@LAD | LAD -113 | 54.7% | 4 | LOSS |
NYY@BOS | OVER 7.5 | 54.3% | 3 | WIN |
KC@PHI | PHI -130 | 58.3% | 4 | WIN |
LAD@SF | OVER 7.5 | 54.7% | 4 | LOSS |
NYM@PHI | PHI -122 | 55.6% | 4 | WIN |
KC@CLE | KC -104 | 52.0% | 3 | WIN |
CIN@SD | JAKE CRONEWORTH OVER 0.5 HITS | 53.1% | 3 | WIN |
WAS@MIA | MIA -123 | 55.2% | 4 | LOSS |
LAA@KC | UNDER 9.5 | 54.9% | 3 | WIN |
TEX@ARI | UNDER 9 | 54.2% | 4 | WIN |
SF@COL | UNDER 11.5 | 56.4% | 6 | LOSS |
SF@COL | RAFAEL DEVERS OVER 1.5 BASES | 56.1% | 6 | WIN |
MIA@WAS | WAS -110 | 54.4% | 4 | WIN |
NYM@DET | OVER 8.5 | 54.5% | 4 | WIN |
TEX@ARI | UNDER 9.5 | 56.4% | 6 | WIN |
TEX@ARI | ALEJANDRO OSUNA UNDER 1.5 BASES | 54.1% | 4 | LOSS |
ATL@CHC | CHC -116 | 55.1% | 3 | WIN |
PHI@MIL | OVER 8.5 | 55.0% | 3 | WIN |
ARI@LAD | SHOHEI OHTANI OVER 2.5 BASES | 54.2% | 4 | WIN |
SEA@CLE | CLE +1.5 | 57.2% | 3 | WIN |
CHC@SF | CHC -105 | 54.1% | 4 | LOSS |
NYY@CHW | RYAN MCMAHON OVER 0.5 BASES | 54.1% | 4 | WIN |
PHI@NYM | OVER 8.5 | 55.6% | 4 | LOSS |
LAA@TEX | LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS | 54.1% | 4 | LOSS |
KC@CHW | KC -109 | 54.2% | 4 | WIN |
SD@SEA | DYLAN CEASE OVER 16.5 OUTS | 53.9% | 3 | LOSS |
SD@SEA | UNDER 8.5 | 54.4% | 4 | LOSS |
MIN@TOR | JOE RYAN UNDER 2.5 EARNED RUNS | 54.1% | 4 | LOSS |
SF@MIL | MIL +100 | 54.0% | 6 | LOSS |
TOR@MIA | MIA +1.5 | 62.0% | 6 | WIN |
CHC@LAA | OVER 9.5 | 54.9% | 4 | LOSS |
BOS@NYY | CARLOS RODON UNDER 4.5 HITS ALLOWED | 54.2% | 4 | WIN |
KC@DET | DET -115 | 56.1% | 5 | WIN |
CHC@LAA | LAA +1.5 | 57.6% | 5 | LOSS |