Twins vs. Cardinals
Prediction, Odds & Props
Mar 30 | MLB AI Picks

Updated: 2025-03-28T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Minnesota Twins will face the St. Louis Cardinals on March 30, 2025, at Busch Stadium in St. Louis, Missouri, concluding their season-opening series. Both teams aim to establish early momentum in the 2025 MLB season.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Mar 30, 2025

Start Time: 2:15 PM EST​

Venue: Busch Stadium​

Cardinals Record: (2-0)

Twins Record: (0-2)

OPENING ODDS

MIN Moneyline: -126

STL Moneyline: +106

MIN Spread: -1.5

STL Spread: +1.5

Over/Under: 8

MIN
Betting Trends

  • In the 2024 season, the Twins had an overall record of 82-80.

STL
Betting Trends

  • The Cardinals finished the 2024 season with an 83-79 overall record.

MATCHUP TRENDS

  • In their 2024 matchups, the Twins and Cardinals split their two-game series, each securing a win.

MIN vs. STL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Walker over 0.5 Total Bases.

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Minnesota vs St. Louis Prediction & Odds:
Free MLB Betting Insights for 3/30/25

The Minnesota Twins and St. Louis Cardinals are set to conclude their season-opening series on March 30, 2025, at Busch Stadium. Both teams are eager to start the 2025 MLB season on a positive note, building upon their performances from the previous year. The Twins finished the 2024 season with an 82-80 record, narrowly missing the playoffs, while the Cardinals posted an 83-79 record, also falling short of postseason contention. During the 2024 season, the Twins and Cardinals faced off in a two-game series in August, with each team securing a victory. The Twins dominated the first game with a 6-0 win, showcasing their offensive capabilities. However, the Cardinals responded in the second game with a narrow 3-2 victory, demonstrating their resilience and ability to perform under pressure. The Twins’ lineup is anchored by key hitters such as Carlos Correa, Byron Buxton, and Royce Lewis. The health and performance of these players are crucial for the team’s success, as they collectively missed significant time due to injuries in the previous season. The addition of outfielder Harrison Bader, who signed a one-year contract with the Twins after his tenure with the New York Mets, provides additional depth and a right-handed bat to the lineup. On the pitching side, the Twins are expected to start Joe Ryan, who missed the last two months of the 2024 season due to a right shoulder injury but had a normal, healthy spring training. The bullpen, featuring closer Jhoan Duran, will play a pivotal role in maintaining leads and securing victories.

The Cardinals, under the leadership of manager Oliver Marmol, rely on a blend of seasoned veterans and emerging talents. First baseman Paul Goldschmidt continues to be a significant offensive force, providing both power and consistency at the plate. Outfielder Lars Nootbaar, despite ongoing arbitration discussions, remains a key contributor, having batted .244 with 12 home runs in the 2024 season. The Cardinals’ pitching rotation is bolstered by the presence of Sonny Gray, who was the scheduled starter for the opening game of the series. For the series finale, the Cardinals may turn to right-hander Andre Pallante, who transitioned to the starting rotation midseason in 2024, ending with an 8-8 record and a 3.78 ERA. The bullpen, led by relievers Ryan Helsley and JoJo Romero, aims to provide stability in the late innings. Defensively, both teams have demonstrated competence, with the Cardinals boasting a fielding percentage that ranked among the top in the National League during the 2024 season. The Twins’ defense is strengthened by the presence of Correa at shortstop and Buxton in center field, both known for their exceptional fielding abilities. This early-season matchup offers both teams an opportunity to assess their rosters and make necessary adjustments as they embark on the long journey of the MLB season. Fans can anticipate a competitive game, with both teams striving to secure a series victory and set a positive tone for the remainder of the season.

Minnesota Twins MLB Preview

The Minnesota Twins travel to Busch Stadium for the conclusion of their three-game series against the St. Louis Cardinals on March 30, 2025, with hopes of building early-season momentum following a bittersweet 2024 campaign. Last season, the Twins finished with an 82-80 record—respectable, yet just shy of securing a playoff spot. Entering 2025, the front office made a few strategic tweaks to reinforce a team that still boasts considerable upside when healthy. Led by manager Rocco Baldelli, Minnesota is looking for more consistency, especially in staying healthy, improving run production, and capitalizing on their strong pitching infrastructure. Facing a Cardinals team with similar postseason aspirations provides a compelling early test for the Twins, who seek to assert themselves once again as a top contender in the American League Central. Minnesota’s lineup remains anchored by two stars who symbolize the team’s ceiling: shortstop Carlos Correa and center fielder Byron Buxton. However, both struggled with injuries in 2024, with Correa limited by plantar fasciitis and Buxton battling various leg issues. The hope for 2025 is that both enter the season fully healthy and capable of producing at their career levels. Correa, known for his clutch postseason performances and elite defense, remains a vocal clubhouse leader. Buxton, when on the field, is one of the most dynamic players in the game, possessing 30-home run power and Gold Glove-caliber defense in center field. Another key piece is Royce Lewis, the former top prospect who emerged as a breakout bat in the second half of last season.

Lewis’s athleticism and advanced approach at the plate make him a rising star capable of carrying the offense for stretches. In an effort to bolster the outfield and provide another right-handed bat, the Twins signed free agent Harrison Bader to a one-year deal in the offseason. Bader brings speed, defensive excellence, and experience to the mix, and he’s expected to platoon with left-handed options while offering valuable insurance in center or right field. Edouard Julien and Max Kepler round out a lineup that blends power with plate discipline, though they’ll need to improve situational hitting to avoid the offensive droughts that plagued them last season. In 2024, Minnesota averaged just under 4.4 runs per game—solid, but not elite—and will look for more balance throughout the order. Pitching remains the bedrock of the Twins’ success. Joe Ryan, who is expected to start the series finale against the Cardinals, is returning from a right shoulder injury that sidelined him in the final months of 2024. The 27-year-old right-hander has a career ERA under 4.00 and is known for his high-spin fastball and aggressive approach. His spring training was reportedly smooth, indicating he’s fully recovered and ready to resume his role near the top of the rotation. The bullpen is led by flamethrowing closer Jhoan Duran, whose triple-digit fastball and wicked curveball make him one of the most intimidating ninth-inning options in the league. Setup men Brock Stewart and Griffin Jax offer reliable depth. Minnesota also plays strong defense, with Correa and Buxton forming a gold-standard up-the-middle pairing when healthy. Ryan Jeffers and Christian Vázquez handle catching duties, offering a mix of game-calling, pop, and veteran presence. With an emphasis on health, depth, and executing fundamentals, the Twins have reason to believe 2025 can be the year they re-establish themselves as legitimate AL contenders. A series win over St. Louis on the road would provide the kind of early momentum needed to kick-start a bounce-back season.

The Minnesota Twins will face the St. Louis Cardinals on March 30, 2025, at Busch Stadium in St. Louis, Missouri, concluding their season-opening series. Both teams aim to establish early momentum in the 2025 MLB season. Minnesota vs St. Louis AI Prediction: Free MLB Betting Insights for Mar 30. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

St. Louis Cardinals MLB Preview

The St. Louis Cardinals return to Busch Stadium on March 30, 2025, aiming to close out their opening series against the Minnesota Twins on a high note and signal their intent to re-enter the playoff conversation after a lukewarm 83-79 campaign in 2024. While they narrowly missed out on the postseason, the organization remains confident that the right pieces are in place to return to their usual standard of contention in the National League Central. With a mix of veteran leadership, ascending young talent, and a bolstered pitching rotation, the Cardinals are setting their sights on consistent performance and resilience throughout the long 162-game journey. The matchup against the Twins presents a quality early-season litmus test, as both teams are closely matched and expected to contend in their respective leagues. The Cardinals’ offense still revolves around the reliable production of first baseman Paul Goldschmidt. Now in his age-37 season, Goldschmidt continues to defy age expectations, finishing 2024 with a .275 average, 24 home runs, and 82 RBIs. While his power numbers have slightly declined, his elite plate discipline and consistent bat remain a stabilizing force in the middle of the lineup. He is joined by Brendan Donovan, who emerged as one of the team’s most versatile and valuable assets last year. Donovan slashed .278 with 14 home runs and played a career-high 153 games in 2024, earning a Gold Glove for his defensive work and flexibility around the infield and outfield. Lars Nootbaar, another key piece in the outfield, contributed 12 homers and a .244 average last year and is expected to take on a larger role this season as he continues to refine his offensive approach.

The team made a significant splash last offseason by signing veteran starter Sonny Gray to anchor the rotation. Gray, coming off a superb campaign with Minnesota in 2024 where he posted a 2.83 ERA, brings a competitive edge and leadership to a pitching staff that struggled with inconsistency last season. While Gray started the opening game of the series, the Cardinals could turn to young right-hander Andre Pallante for the series finale. Pallante transitioned to the rotation midway through last year, ending with an 8-8 record and a 3.78 ERA. He’s shown the ability to induce weak contact and work efficiently through lineups, making him a key depth piece in the rotation. The bullpen remains strong, with Ryan Helsley serving as the closer and setup men like JoJo Romero and John King ready to hold down late-inning leads. Defensively, St. Louis continues to be among the best in baseball, especially in the infield. Goldschmidt and Donovan provide stability on the corners, while Tommy Edman and Nolan Gorman bring speed and arm strength up the middle. The Cardinals also made a minor but strategic move by claiming left-handed reliever Bailey Horn off waivers from Detroit, adding another bullpen option with upside. With solid pitching, a disciplined lineup, and excellent defense, the Cardinals are well-positioned to make a push in 2025. A win over the Twins in the finale would be a valuable early statement and a reminder that St. Louis, even after a year off the playoff stage, remains a threat in the National League.

Minnesota vs. St. Louis Prop Picks (AI)

AI algorithm Remi is pouring through mountains of stats on each line. In fact, anytime the Twins and Cardinals play there’s always several intriguing observations to key in on. Not to mention games played at Busch Stadium in Mar can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: J. Walker over 0.5 Total Bases.

Minnesota vs. St. Louis Prediction (AI)

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Remi, our AI sports wizard, has been pouring over mountains of data from every past game between the Twins and Cardinals and using recursive machine learning and impressive AI to crunch the data to a single cover probability.

The Algorithm has been most watching on the unproportionally assigned weight emotional bettors often put on Minnesota’s strength factors between a Twins team going up against a possibly tired Cardinals team. It appears the true game analytics might reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our MLB AI picks for FREE now.

Below is our current AI Minnesota vs St. Louis picks, computer picks Twins vs Cardinals, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full MLB schedule.

Twins Betting Trends

In the 2024 season, the Twins had an overall record of 82-80.

Cardinals Betting Trends

The Cardinals finished the 2024 season with an 83-79 overall record.

Twins vs. Cardinals Matchup Trends

In their 2024 matchups, the Twins and Cardinals split their two-game series, each securing a win.

Minnesota vs. St. Louis Game Info

Minnesota vs St. Louis starts on March 30, 2025 at 2:15 PM EST.

Spread: St. Louis +1.5
Moneyline: Minnesota -126, St. Louis +106
Over/Under: 8

Minnesota: (0-2)  |  St. Louis: (2-0)

Remi's searched hard and found the best prop for this matchup: J. Walker over 0.5 Total Bases.. Prices move—always shop for the best number.

In their 2024 matchups, the Twins and Cardinals split their two-game series, each securing a win.

MIN trend: In the 2024 season, the Twins had an overall record of 82-80.

STL trend: The Cardinals finished the 2024 season with an 83-79 overall record.

See our latest MLB picks and odds pages for 2025 to compare prices before you bet.

Minnesota vs. St. Louis Odds

Remi is pouring through tons of data points on each player. In fact, anytime the Minnesota vs St. Louis trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps almost always follow normal, predictable patterns.

Minnesota vs St. Louis Opening Odds

MIN Moneyline: -126
STL Moneyline: +106
MIN Spread: -1.5
STL Spread: +1.5
Over/Under: 8

Minnesota vs St. Louis Live Odds

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3
+750
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O 5.5 (-112)
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3
0
-3500
+1060
-3.5 (+132)
+3.5 (-178)
O 5.5 (+122)
U 5.5 (-162)
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Detroit Tigers
Boston Red Sox
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Tigers
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2
1
-330
+240
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O 5.5 (+148)
U 5.5 (-200)
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Chicago White Sox
Washington Nationals
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White Sox
Nationals
4
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-670
+430
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+2.5 (-102)
O 10.5 (+104)
U 10.5 (-138)
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Minnesota Twins
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In Progress
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0
0
+194
-235
+1.5 (-108)
-1.5 (-111)
O 8.5 (-115)
U 8.5 (-105)
Sep 27, 2025 7:11PM EDT
Cincinnati Reds
Milwaukee Brewers
9/27/25 7:11PM
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+116
-134
+1.5 (-184)
-1.5 (+152)
O 8 (-110)
U 8 (-110)
Sep 27, 2025 7:15PM EDT
Pittsburgh Pirates
Atlanta Braves
9/27/25 7:15PM
Pirates
Braves
+144
-172
+1.5 (-140)
-1.5 (+116)
O 8 (-118)
U 8 (-104)
Sep 27, 2025 7:16PM EDT
Texas Rangers
Cleveland Guardians
9/27/25 7:16PM
Rangers
Guardians
+130
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+1.5 (-176)
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O 7.5 (+100)
U 7.5 (-122)
Sep 27, 2025 8:40PM EDT
Arizona Diamondbacks
San Diego Padres
9/27/25 8:40PM
Diamondbacks
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+130
-154
+1.5 (-166)
-1.5 (+138)
O 7.5 (-105)
U 7.5 (-115)
Sep 27, 2025 9:39PM EDT
Houston Astros
Los Angeles Angels
9/27/25 9:39PM
Astros
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-146
+124
-1.5 (+112)
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O 9 (-108)
U 9 (-112)
Sep 27, 2025 9:41PM EDT
Los Angeles Dodgers
Seattle Mariners
9/27/25 9:41PM
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+100
-118
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O 7 (-118)
U 7 (-104)
Sep 27, 2025 10:05PM EDT
Kansas City Royals
Oakland Athletics
9/27/25 10:05PM
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+100
-118
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O 10 (-114)
U 10 (-106)
Sep 28, 2025 3:06PM EDT
Baltimore Orioles
New York Yankees
9/28/25 3:06PM
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Yankees
+144
-172
+1.5 (-146)
-1.5 (+122)
O 9 (-122)
U 9 (+100)
Sep 28, 2025 3:06PM EDT
Colorado Rockies
San Francisco Giants
9/28/25 3:06PM
Rockies
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+270
-335
+1.5 (+112)
-1.5 (-134)
O 7.5 (-110)
U 7.5 (-110)
Sep 28, 2025 3:06PM EDT
Minnesota Twins
Philadelphia Phillies
9/28/25 3:06PM
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+180
-215
+1.5 (-130)
-1.5 (+108)
O 8 (-122)
U 8 (+100)

MLB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Minnesota Twins vs. St. Louis Cardinals on March 30, 2025 at Busch Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our MLB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
ARI@SD SD -131 57.3% 4 WIN
DET@BOS BOS -115 56.4% 5 WIN
NYM@CHC NYM -110 54.1% 3 WIN
HOU@ATH ATH +118 50.8% 4 WIN
NYM@CHC OVER 7 54.5% 3 WIN
STL@SF OVER 7.5 55.9% 5 LOSS
KC@LAA TYLER TOLBERT UNDER 1.5 BASES 54.4% 4 WIN
MIL@SD UNDER 9 54.7% 4 WIN
MIA@PHI KYLE SCHWARBER OVER 1.5 HITS+RUNS+RBIS 53.3% 3 WIN
WAS@NYM OVER 8.5 56.1% 6 LOSS
LAA@COL COL +108 50.5% 3 WIN
TOR@KC UNDER 9 54.7% 4 LOSS
SEA@KC KC +1.5 62.3% 5 LOSS
NYY@MIN OVER 9 55.1% 4 WIN
MIA@COL OVER 10.5 55.0% 4 WIN
MIA@COL AGUSTIN RAMIREZ OVER 1.5 HITS+RUNS+RBIS 54.3% 4 WIN
SEA@KC BOBBY WITT UNDER 0.5 SINGLES 54.4% 4 LOSS
PHI@LAD LAD -113 54.7% 4 LOSS
NYY@BOS OVER 7.5 54.3% 3 WIN
KC@PHI PHI -130 58.3% 4 WIN
LAD@SF OVER 7.5 54.7% 4 LOSS
NYM@PHI PHI -122 55.6% 4 WIN
KC@CLE KC -104 52.0% 3 WIN
CIN@SD JAKE CRONEWORTH OVER 0.5 HITS 53.1% 3 WIN
WAS@MIA MIA -123 55.2% 4 LOSS
LAA@KC UNDER 9.5 54.9% 3 WIN
TEX@ARI UNDER 9 54.2% 4 WIN
SF@COL UNDER 11.5 56.4% 6 LOSS
SF@COL RAFAEL DEVERS OVER 1.5 BASES 56.1% 6 WIN
MIA@WAS WAS -110 54.4% 4 WIN
NYM@DET OVER 8.5 54.5% 4 WIN
TEX@ARI UNDER 9.5 56.4% 6 WIN
TEX@ARI ALEJANDRO OSUNA UNDER 1.5 BASES 54.1% 4 LOSS
ATL@CHC CHC -116 55.1% 3 WIN
PHI@MIL OVER 8.5 55.0% 3 WIN
ARI@LAD SHOHEI OHTANI OVER 2.5 BASES 54.2% 4 WIN
SEA@CLE CLE +1.5 57.2% 3 WIN
CHC@SF CHC -105 54.1% 4 LOSS
NYY@CHW RYAN MCMAHON OVER 0.5 BASES 54.1% 4 WIN
PHI@NYM OVER 8.5 55.6% 4 LOSS
LAA@TEX LOGAN OHOPPE OVER 1.5 HITS+RUNS+RBIS 54.1% 4 LOSS
KC@CHW KC -109 54.2% 4 WIN
SD@SEA DYLAN CEASE OVER 16.5 OUTS 53.9% 3 LOSS
SD@SEA UNDER 8.5 54.4% 4 LOSS
MIN@TOR JOE RYAN UNDER 2.5 EARNED RUNS 54.1% 4 LOSS
SF@MIL MIL +100 54.0% 6 LOSS
TOR@MIA MIA +1.5 62.0% 6 WIN
CHC@LAA OVER 9.5 54.9% 4 LOSS
BOS@NYY CARLOS RODON UNDER 4.5 HITS ALLOWED 54.2% 4 WIN
KC@DET DET -115 56.1% 5 WIN
CHC@LAA LAA +1.5 57.6% 5 LOSS