Away Team
Record 2-0
Last 5 4-1 last five
ATS 2-0-0 ATS
Road 0-0 road
Standings
CFB Game Preview
Schedule
Kickoff Countdown
5d 07:44:35
Start Time 8:00 PM EST
Date September 25, 2026
Venue Merchants Bank Field at Memorial Stadium
Where To Watch FOX
Where To Stream FOX One
Season Series 2026 series tied 0-0.

Indiana brings a 3-0 record but an 0-3 ATS mark into Friday night's Big Ten opener, while unbeaten Northwestern has covered twice and just crushed Colorado. The spread sits above three touchdowns, putting margin and Indiana's run-game edge under the microscope.

Home Team
Record 3-0
Last 5 5-0 last five
ATS 0-3-0 ATS
Home 3-0 home
Analysis Updated: 8:13 AM ET
Injuries Checked: 8:12 AM ET
Odds Updated: 12:04 PM ET

Betting Snapshot

Spread
IND -23.5
Open: IND -23.5
Market Steady

Spread Movement

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Odds Updated: 9/20 12:04 PM ET
Moneyline
IND -4000
Open: IND -4000
Market Steady

Moneyline Movement

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Odds Updated: 9/20 12:04 PM ET
Total
47.5
Open: 47.5
Total Steady

Total Movement

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Odds Updated: 9/20 12:04 PM ET

Best Free Prop Pick

FREE PROP
Remi's Still Searching
Turbo Richard Over 0.5 rushing touchdowns: he has scored on the ground in all three games. Turbo Richard Over 0.5 rushing touchdowns: Northwestern allowed South Dakota State a rushing score in Week 1. Turbo Richard Over 0.5 rushing touchdowns: Indiana's 23.5-point favorite role supports repeated red-zone rushing chances.

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Odds Comparison Center

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Best Home Spread
FanDuel | IND -22.5
Best Home Moneyline
MyBookie.ag | IND -2500
Best Over Line
FanDuel | 47.5
Best Away Spread
DraftKings | NWEST +23.5
Best Away Moneyline
Fanatics | NWEST +1800
Best Under Line
BetRivers | 48
Updated 12:04 PM ET
Sportsbook Spread Moneyline Total
FanDuelNWEST +22.5
IND -22.5
NWEST +1280
IND -3500
O 47.5
U 47.5
DraftKingsNWEST +23.5
IND -23.5
NWEST +1600
IND -4000
O 47.5
U 47.5
BetRiversNWEST +23.5
IND -23.5
NWEST +1400
IND -5000
O 48
U 48
FanaticsNWEST +23.5
IND -23.5
NWEST +1800
IND -4000
O 47.5
U 47.5
MyBookie.agNWEST +23.5
IND -23.5
NWEST +910
IND -2500
O 47.5
U 47.5

Injury Report

Northwestern receiver Hayden Eligon II remains listed questionable with a lower-body issue, and starting lineman Ezomo Oratokhai exited the Colorado win with an ankle injury. Indiana entered its Western Kentucky game without kicker Nico Radicic because of a back issue and receiver Lebron Bond because of an undisclosed injury. Friday's Big Ten availability report will be important before kickoff, especially for Northwestern's protection unit.

Key Players

Northwestern
Aidan Chiles
Completed 17 of 22 for 241 yards and three touchdowns against Colorado.
Indiana
Turbo Richard
Ran 15 times for 149 yards and a touchdown against Western Kentucky.

Key Matchup Edge

Indiana's run game owns the clearest structural edge. Turbo Richard has 315 yards on 41 carries, including 149 against Western Kentucky, while Northwestern allowed Colorado to rush for 180 yards despite winning 41-7. If Indiana stays ahead of schedule, sustained rushing success can shorten third downs, protect Hoover and steadily pressure the large spread.

3 Things to Watch

  • Northwestern protection after Oratokhai's ankle exit
  • Turbo Richard against Northwestern's run fits
  • Indiana's 0-3 ATS start

Betting Breakdown

Indiana enters its Big Ten opener 3-0, but the market is asking bettors to lay more than three touchdowns against a Northwestern team that has covered both of its 2026 games. The Hoosiers have been dominant on the scoreboard, outscoring North Texas, Howard and Western Kentucky 145-16, yet they failed to cover each enormous closing spread. Northwestern is 2-0 after beating South Dakota State 34-18 and Colorado 41-7, with Aidan Chiles coming off a five-touchdown performance and the Wildcats generating four first-half takeaways against Colorado. The matchup gets tougher in Bloomington. Indiana's defense has allowed only 5.3 points and 203.3 yards per game, while its offense is balanced by Josh Hoover's efficiency and Turbo Richard's 315 rushing yards. Northwestern's best path to staying inside roughly +23.5 is avoiding early turnovers, protecting Chiles, and forcing Indiana into longer drives. Indiana's clearest route to separation is the ground game against a Wildcats front that surrendered 180 rushing yards to Colorado. The 47.5 total also makes every Northwestern scoring chance valuable.

Northwestern Betting Outlook

Northwestern has been one of the early betting surprises, starting 2-0 straight up and 2-0 ATS while averaging 37.5 points. Aidan Chiles has thrown for 514 yards with four touchdowns and no interceptions through two games, and his mobility adds another stress point for defenses. The concern is how that efficiency travels against Indiana's defense, which has allowed only 5.3 points per game. Northwestern has not played a road game yet, and the offensive line may be worth monitoring after Ezomo Oratokhai's ankle exit against Colorado. To threaten the spread, the Wildcats need clean possessions, explosive plays and another strong takeaway margin.

Indiana Betting Outlook

Indiana is 3-0 and has outscored opponents 145-16, yet the Hoosiers are 0-3 ATS because every game carried a massive favorite price. Josh Hoover has been exceptionally efficient, throwing for 649 yards, 10 touchdowns and no interceptions, while Turbo Richard leads the ground game with 315 yards and four scores. Charlie Becker has added 272 receiving yards, giving Indiana multiple ways to stress a Northwestern defense that just allowed Colorado 180 rushing yards. The betting question is not whether Indiana can control the game, but whether it can create enough margin to clear more than three touchdowns against a confident, explosive Northwestern offense.

Latest Team Buzz

Northwestern Wildcats vs Indiana Hoosiers FAQ

What is the current spread for Northwestern Wildcats vs Indiana Hoosiers?

The current home spread is IND -23.5, while the away spread is NWEST +23.5.

How far has the spread moved for Northwestern Wildcats vs Indiana Hoosiers?

The spread opened at IND -23.5 and is now IND -23.5.

What is the current moneyline for Northwestern Wildcats vs Indiana Hoosiers?

The current moneyline is NWEST +1600 / IND -4000.

How far has the moneyline moved for Northwestern Wildcats vs Indiana Hoosiers?

The moneyline opened at NWEST +1600 / IND -4000 and is now NWEST +1600 / IND -4000.

What is the current total for Northwestern Wildcats vs Indiana Hoosiers?

The current total is 47.5.

How far has the total moved for Northwestern Wildcats vs Indiana Hoosiers?

The total opened at 47.5 and is now 47.5.

Is the market taking the underdog in Northwestern Wildcats vs Indiana Hoosiers?

Current market signal: Market Steady.

Is the market taking the favorite in Northwestern Wildcats vs Indiana Hoosiers?

Current market signal: Market Steady.

Is the total dropping for Northwestern Wildcats vs Indiana Hoosiers?

Current totals signal: Total Steady.

Is the total rising for Northwestern Wildcats vs Indiana Hoosiers?

Current totals signal: Total Steady.

Where to watch Northwestern Wildcats vs Indiana Hoosiers?

You can watch this game on FOX. For the latest broadcast details, see Where to Watch.

Where to stream Northwestern Wildcats vs Indiana Hoosiers?

You can stream this game on FOX One.

What is the best free prop bet for Northwestern Wildcats vs Indiana Hoosiers?

Remi's Still Searching

What is the biggest matchup edge for Northwestern Wildcats vs Indiana Hoosiers?

Indiana's run game owns the clearest structural edge. Turbo Richard has 315 yards on 41 carries, including 149 against Western Kentucky, while Northwestern allowed Colorado to rush for 180 yards despite winning 41-7. If Indiana stays ahead of schedule, sustained rushing success can shorten third downs, protect Hoover and steadily pressure the large spread.

REMI AI PERFORMANCE

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement. We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

Matchup Northwestern Wildcats vs. Indiana Hoosiers
Game Date September 25, 2026
Venue Merchants Bank Field at Memorial Stadium
RECENT COMPLETED PICKS

AI CFB PAST PICKS

29-22 56.9% WIN
GAME
LEAN
WIN %
UNITS
RESULT
JMAD@SDGST
UNDER 46.5
57.1%
7
WIN
MISSST@SC
OVER 58.5
58.1%
8
WIN
FRESNO@SJST
OVER 47.5
58.1%
8
LOSS
UL@USC
OVER 59.5
56.9%
6
WIN
MEMP@BOISE
UNDER 56.5
56.9%
6
LOSS
CAL@CUSE
UNDER 57.5
56.9%
6
WIN
RICE@ND
OVER 54.5
57.0%
6
LOSS
RUT@BC
UNDER 54.5
56.9%
6
WIN
WASHST@WASH
OVER 51.5
56.9%
6
LOSS
TOWSON@NAVY
OVER 51
57.4%
7
WIN
FURMAN@TENN
OVER 67.5
57.1%
7
LOSS
MIAOH@PITT
UNDER 47.5
57.2%
7
LOSS
UTEP@OKLA
OVER 51.5
56.9%
6
LOSS
ALBANY@BUFF
ALBANY +18.5
54.1%
4
WIN
ALBANY@BUFF
UNDER 47.5
57.1%
7
WIN
UAB@ILL
KATIN HOUSER OVER 18.5 PASS COMP
54.2%
4
LOSS
HAWAII@STNFRD
HAWAII +4.5
54.8%
4
LOSS
MEMP@UNLV
UNLV -4
53.2%
3
LOSS
SJST@USC
OVER 61.5
57.0%
6
WIN
JAXST@NDAKST
UNDER 46.5
56.8%
6
WIN
NCST@UVA
CJ BAILEY OVER 29.5 PASS ATT
54.2%
4
LOSS
MIAMI@IND
ROMAN HEMBY UNDER 15.5 RUSH ATT
55.2%
5
LOSS
OLEMISS@GEORGIA
KEWAN LACY ANYTIME TD
56.7%
6
WIN
BAMA@IND
FERNANDO MENDOZA UNDER 26.5 PASS ATT
55.2%
5
WIN
OREG@TXTECH
OREG -126
58.9%
6
WIN
NEB@UTAH
DEVON DAMPIER UNDER 185.5 PASS YDS
53.4%
3
LOSS
NOTEX@SDGST
NOTEX -7
54.2%
4
LOSS
BAMA@OKLA
ISAIAH SATEGNA III ANYTIME TD
54.2%
4
WIN
BYU@TTU
PARKER KINGSTON OVER 20.5 LONGEST RECEPTION
54.3%
4
WIN
UNLV@BOISE
BOISE -4.5
56.7%
6
WIN
ECU@FAU
FAU +7
57.8%
7
LOSS
OREG@WASH
WASH +7
54.9%
4
LOSS
WYO@HAWAII
WYO +7.5
55.1%
5
LOSS
COLO@KSTATE
COLO +17.5
54.0%
4
WIN
OHIOST@MICH
MICH +10.5
56.4%
6
LOSS
VATECH@UVA
VATECH +8
57.8%
7
LOSS
NWEST@ILL
LUKE ALTMYER UNDER 19.5 PASS COMP
54.3%
4
WIN
ORE@WAS
DEMOND WILLIAMS JR UNDER 43.5 RUSH YDS
55.2%
5
WIN
MIAMI@VATECH
VATECH +18.5
54.2%
4
WIN
GAST@TROY
TROY -9.5
55.7%
5
WIN
DEL@WAKE
DEL +18
56.7%
6
LOSS
NMEX@AF
NMEX -3.5
56.1%
5
WIN
WASHST@JMAD
WASHST +14.5
55.3%
5
WIN
ILL@WISC
WISC +9
55.1%
5
WIN
WKY@LSU
WKY +23.5
56.3%
6
WIN
WASH@UCLA
DEMOND WILLIAMS UNDER 27.5 PASS ATT
56.3%
6
WIN
TCU@HOU
AMARE THOMAS OVER 69.5 RECV YDS
55.2%
5
WIN
TEX@UGA
NATE FRAZIER UNDER 65.5 RUSH + REC YDS
55.5%
5
WIN
PUR@WASH
ANTONIO HARRIS UNDER 73.5 RUSH + REC YDS
54.1%
4
WIN
UVA@DUKE
DUKE -3.5
54.7%
3
LOSS
OKLA@BAMA
BAMA -6
54.5%
3
LOSS
Past performance is not a guarantee of future results. Picks are displayed for informational purposes only.