Cornhuskers vs. Nittany Lions
FREE CFB AI Predictions
November 22, 2025



Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
AI Sports Betting Algorithm Remi

GAME INFO

Date: Nov 22, 2025

Start Time: ​

Venue: ​

Nittany Lions Record:

Cornhuskers Record:

OPENING ODDS

NEB Moneyline:

PSU Moneyline:

NEB Spread:

PSU Spread:

Over/Under:

NEB
Betting Trends

PSU
Betting Trends

MATCHUP TRENDS

NEB vs. PSU
Best Prop Bet

LIVE CFB ODDS

CFB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
295-209
VAULT
NET UNITS
(INCL VIG)
+417.7
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$41,768
EXECUTIVE
VS. SPREAD
1519-1315
EXECUTIVE
NET UNITS
(INCL VIG)
+312.6
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$31,258

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Nebraska vs Penn State AI Prediction:
Free CFB Betting Insights for 11/22/25

Cornhuskers AI Preview

 Nebraska vs Penn State AI Prediction: Free CFB Betting Insights for Nov 22. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Nittany Lions AI Preview

Cornhuskers vs. Nittany Lions FREE Prop Pick

AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the Cornhuskers and Nittany Lions play there’s always several intriguing angles to key in on. Not to mention games played at in Nov rarely follow normal, predictable betting trends.

Nebraska vs. Penn State CFB AI Pick

Remi Robot Icon

Remi, our AI sports genius, has been pouring over mountains of data from every simulation between the Cornhuskers and Nittany Lions and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.

Remi has been most fixated on the unproportionally assigned weight human bettors regularly put on player performance factors between a Cornhuskers team going up against a possibly improved Nittany Lions team. In reality, the true game analytics appear to reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.