East Carolina vs UTSA Prediction — AI Finds CAN'T MISS CFB Lines & Props (Nov 22)
Updated: 2025-11-15T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The East Carolina Pirates will travel to face the UTSA Roadrunners on November 22, 2025 in a matchup that features one of the stronger teams in the American Athletic Conference visiting a Roadrunners squad that has shown offensive production but defensive leeway. East Carolina enters with a strong two-way profile, while UTSA has posted solid scoring numbers yet continues to struggle to stop opponents—setting up an interesting regional and situational duel.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Nov 22, 2025
Start Time: 4:30 PM EST
Venue: Alamodome
Roadrunners Record: (5-5)
Pirates Record: (7-3)
OPENING ODDS
ECAR Moneyline: -133
UTSA Moneyline: +112
ECAR Spread: -2.5
UTSA Spread: +2.5
Over/Under: 62.5
ECAR
Betting Trends
- East Carolina averages about 33.6 points per game and allows around 18.3 points per game this season, placing them among the FBS leaders in scoring margin and suggesting strong ATS potential when they are underdogs or visiting.
UTSA
Betting Trends
- UTSA posts approximately 32.3 points per game while surrendering about 30.4 points per game, situating them well in offensive output but among the weaker units in defensive ranking—an unstable home-favorite ATS profile.
MATCHUP TRENDS
- Given East Carolina’s strong defensive margin and UTSA’s defensive vulnerabilities, the spread may lean toward the Pirates covering, especially on the road. Meanwhile the total might lean toward the “under” if East Carolina controls possession, limits UTSA’s explosive plays, and the Roadrunners struggle to sustain drives—despite UTSA’s scoring capability.
ECAR vs. UTSA
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: REMI'S STILL ANALYZING MARKETS
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East Carolina vs UTSA Prediction & Odds:
Free CFB Betting Insights for 11/22/25
The November 22, 2025 matchup between East Carolina and UTSA sets up as a compelling contrast of structure, discipline, volatility, and pace, with the Pirates entering as one of the most balanced and efficient teams in the American Athletic Conference while the Roadrunners come in boasting significant offensive firepower but saddled with defensive vulnerabilities that have repeatedly placed them in high-variance, shootout-leaning situations. East Carolina arrives with a strong 7–3 profile rooted in complementary football: they average over 33 points per game, allow fewer than 19, convert more than half of their third-down attempts, and maintain a red-zone efficiency rate near 80 percent, producing an identity built on sustained drives, consistency, and disciplined execution across all four quarters. Their defense, one of the most underrated in the conference, holds opponents to roughly 5.1 yards per play and excels in first-down containment, which forces opponents into long-yardage sequences—an especially important trait against a UTSA offense that thrives on rhythm, spacing, and explosive plays when ahead of the chains. The Roadrunners, averaging just over 32 points per game, possess the offensive potency to challenge most teams at home through tempo manipulation, vertical passing threats, and a capable backfield that can punish defenses lacking gap discipline, but their defensive shortcomings—allowing over 30 points per game—have repeatedly put them in situations where the offense must shoulder unsustainable loads. This interplay forms the core dynamic of the matchup: whether East Carolina can impose a controlled, methodical pace that limits UTSA’s possessions and magnifies defensive weaknesses or whether UTSA can force early volatility, accelerate the game’s tempo, and exploit ECU’s occasional susceptibility to big-play bursts.
Field position will be a crucial hinge, as UTSA’s defense becomes far more vulnerable on short fields, whereas ECU’s defense thrives when opponents must sustain lengthy drives. Special teams may also tilt momentum: ECU’s more consistent coverage and kicking units give them opportunities to win hidden-yardage margins, while UTSA must avoid miscues that hand the Pirates additional possessions or shorter distances. Emotionally, UTSA benefits from home-field energy and a fan base that can elevate the offense, but East Carolina’s maturity, balance, and identity give them an edge in adverse environments. Turnovers and red-zone decision-making may ultimately determine the game’s trajectory, as UTSA’s path to victory likely requires forcing ECU into rare mistakes or stolen possessions that offset their defensive liabilities. East Carolina, on the other hand, simply needs to execute their identity: sustain long drives, limit explosive plays, communicate cleanly on defense, and avoid giving UTSA openings to push the tempo beyond ECU’s preferred pace. In the end, the matchup leans structurally toward East Carolina because of their superior balance, stronger fundamentals, and resilience in both situational and field-position metrics, but UTSA’s offensive volatility ensures that if the Roadrunners catch rhythm early or break the game open with explosive gains, the contest could remain competitive longer than the numbers suggest, creating a chess match of discipline versus momentum.
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Cast your vote for the best QB performance of the week! 👇 @katinhouser https://t.co/ghb5sNDNG0 pic.twitter.com/aaGDvy3sqJ
— ECU Football (@ECUPiratesFB) November 17, 2025
East Carolina Pirates CFB Preview
East Carolina enters its November 22, 2025 road matchup against UTSA with one of the most complete and balanced profiles in the American Athletic Conference, carrying the identity of a disciplined, efficient, and well-structured team that has consistently controlled games through complementary football while minimizing mistakes and winning situational battles. Averaging more than 33 points per game with an offense that converts over 50 percent of its third downs and scores on nearly 80 percent of its red-zone trips, the Pirates operate with methodical precision built around a balanced run-pass approach, strong early-down execution, and a quarterback who manages the game efficiently without forcing throws or inviting high-variance turnovers. Their ability to sustain long drives and dictate pace puts pressure on opponents to match their efficiency, something UTSA’s defense—which allows over 30 points per game—has struggled to do against teams with physical run games and stable passing structures. Defensively, East Carolina presents the kind of profile that travels well: allowing fewer than 19 points per game, holding opponents to a low success rate on early downs, and consistently tackling with discipline to limit yards after contact. Their front manages gaps well, their linebackers flow with assignment integrity, and their secondary avoids catastrophic breakdowns, all of which will be critical against a UTSA offense that thrives on spacing, tempo, and explosive play designs. On the road, ECU must stay committed to its identity—control the line of scrimmage, avoid pre-snap penalties, maintain communication, and prevent UTSA’s home crowd from injecting momentum into the game through quick scores or special-teams jolts.
The Pirates also need to manage field position carefully; short fields favor UTSA’s offensive volatility, while long fields suit ECU’s defensive patience and structure. Special teams execution becomes a quiet but important factor, as ECU’s consistency in coverage and punting can neutralize UTSA’s return threats and set the tone for a field-position battle that inherently favors the more complete defense. Psychologically, ECU enters with confidence but cannot afford complacency; UTSA’s offense has enough firepower to punish lapses, especially if ECU’s defense loses its early-down edge or if the Pirates turn the ball over in vulnerable parts of the field. The key for East Carolina is to avoid letting the contest become a high-tempo shootout—an environment that levels the playing field and blunts their structural advantages. If the Pirates play their style—sustained drives, disciplined defensive fits, and clean special teams—they possess a high probability of controlling the flow, silencing the crowd, and securing a valuable road win. Their balanced roster, superior two-way efficiency, and situational stability furnish them with multiple paths to victory, provided they maintain composure and force UTSA to drive the long way in a game where precision matters more than volatility.
Credit: USA TODAY/IMAGN
UTSA Roadrunners CFB Preview
UTSA enters its November 22, 2025 home matchup against East Carolina with the potent offensive identity that has long defined the Roadrunners, but also with the defensive vulnerabilities that have repeatedly forced them into high-variance, track-meet-style games, making discipline, tempo, and situational execution paramount as they face one of the most balanced teams in the American Athletic Conference. Averaging just over 32 points per game, UTSA’s offense has the firepower to challenge any opponent, built on explosive vertical concepts, quick-motion formations, and a run game capable of generating chunk yardage when the offensive line gains early leverage. Their quarterback-driven system thrives on rhythm and spacing, and when UTSA gets ahead of the chains, they can apply stress on every level of a defense. But the challenge here is that East Carolina not only allows fewer than 19 points per game but also maintains exceptional discipline in limiting explosives, forcing long drives, and closing out possessions with strong red-zone efficiency. For UTSA to compete, they must create volatility—hit early shot plays, leverage home-field energy, and push tempo aggressively enough to pull ECU out of its preferred methodical style. Defensively, UTSA must rise significantly above their season baseline of allowing over 30 points per game, improving communication in the secondary, tightening pursuit angles, and winning enough early-down battles to prevent ECU’s efficient offense from controlling possession.
Assignment discipline will be crucial, as ECU converts more than half of its third downs, and UTSA cannot afford repeated defensive lapses that extend drives and drain their own offensive rhythm. Special teams further magnify the stakes: the Roadrunners must avoid hidden-yardage losses, limit ECU’s return game, and create at least one momentum-swinging play to offset their defensive disadvantages. Field position is particularly vital—short fields could give UTSA’s offense the spark needed to match ECU, while long fields could strain the Roadrunners’ ability to string together mistake-free drives. Psychologically, UTSA benefits from their home environment, a crowd capable of energizing fast starts and elevating defensive intensity in spurts, but they must also avoid the emotional swings that have at times produced inconsistency or rushed decisions. Their optimal path to victory lies in forcing East Carolina into a less comfortable, higher-tempo game—one where UTSA’s explosiveness becomes an equalizer and ECU’s defensive structure is tested repeatedly rather than patiently. If the Roadrunners strike early, protect the football, and deliver their most disciplined defensive outing of the season, they can keep this matchup competitive deep into the fourth quarter. Otherwise, ECU’s balance, stability, and situational sharpness may slowly widen the margin, making UTSA’s offensive heroics insufficient to compensate for defensive gaps.
Week 12 Honorable Mention: @UTSAFTBL RB Will Henderson, III (Gilmer HS, TX) #BirdsUp @Willthegoat1011 pic.twitter.com/KRLNsGKF7k
— Earl Campbell Award (@CampbellAward) November 18, 2025
East Carolina vs UTSA Prop Picks (AI)
Remi is pouring through mountains of datapoints on each line. In fact, anytime the Pirates and Roadrunners play there’s always several intriguing angles to key in on. Not to mention games played at Alamodome in Nov almost always follow normal, predictable betting trends.
East Carolina vs UTSA Prediction (AI)
Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every past game between the Pirates and Roadrunners and using recursive machine learning and industry leading AI to analyze the data to a single cover probability.
Interestingly enough, the data has been most watching on the linear correlation of weight human bettors tend to put on coaching factors between a Pirates team going up against a possibly strong Roadrunners team. In reality, the true game analytics might reflect a slight lean against one Vegas line in particular.
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Below is our current AI East Carolina vs UTSA picks, computer picks Pirates vs Roadrunners, best bets, model edges, confidence ratings.
| DATE | GAME | LEAN | %WIN | UNITS | LEVEL | |
|---|---|---|---|---|---|---|
| CFB | 12/5 | NOTEX@TULANE | UNLOCK THIS PICK | 7 |
VAULT v4
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| CFB | 12/5 | UNLV@BOISE | UNLOCK THIS PICK | 6 |
VAULT v2
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| CFB | 12/5 | NOTEX@TULANE | UNLOCK THIS PICK | 2 |
INTEL
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These picks update as information changes—injury reports, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
East Carolina Betting Trends
East Carolina averages about 33.6 points per game and allows around 18.3 points per game this season, placing them among the FBS leaders in scoring margin and suggesting strong ATS potential when they are underdogs or visiting.
UTSA Betting Trends
UTSA posts approximately 32.3 points per game while surrendering about 30.4 points per game, situating them well in offensive output but among the weaker units in defensive ranking—an unstable home-favorite ATS profile.
Pirates vs. Roadrunners Matchup Trends
Given East Carolina’s strong defensive margin and UTSA’s defensive vulnerabilities, the spread may lean toward the Pirates covering, especially on the road. Meanwhile the total might lean toward the “under” if East Carolina controls possession, limits UTSA’s explosive plays, and the Roadrunners struggle to sustain drives—despite UTSA’s scoring capability.
East Carolina vs. UTSA Game Info
East Carolina vs UTSA starts on November 22, 2025 at 4:30 PM EST.
Venue: Alamodome.
Spread: UTSA +2.5
Moneyline: East Carolina -133, UTSA +112
Over/Under: 62.5
East Carolina: (7-3) | UTSA: (5-5)
Remi's searched hard and found the best prop for this matchup: REMI'S STILL ANALYZING MARKETS. Prices move—always shop for the best number.
Given East Carolina’s strong defensive margin and UTSA’s defensive vulnerabilities, the spread may lean toward the Pirates covering, especially on the road. Meanwhile the total might lean toward the “under” if East Carolina controls possession, limits UTSA’s explosive plays, and the Roadrunners struggle to sustain drives—despite UTSA’s scoring capability.
ECAR trend: East Carolina averages about 33.6 points per game and allows around 18.3 points per game this season, placing them among the FBS leaders in scoring margin and suggesting strong ATS potential when they are underdogs or visiting.
UTSA trend: UTSA posts approximately 32.3 points per game while surrendering about 30.4 points per game, situating them well in offensive output but among the weaker units in defensive ranking—an unstable home-favorite ATS profile.
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
East Carolina vs. UTSA Odds
AI algorithm Remi is pouring through tons of data points on each line. In fact, anytime the East Carolina vs UTSA trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable betting trends.
| ECAR Moneyline | -133 |
|---|---|
| UTSA Moneyline | +112 |
| ECAR Spread | -2.5 |
| UTSA Spread | +2.5 |
| Over / Under | 62.5 |
East Carolina vs UTSA Live Odds
| Games | PTS | ML | SPR | O/U | |
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Kennesaw State Owls
Jacksonville State Gamecocks
In Progress
KENSAW
JAXST
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7
0
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-500
+330
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-8.5 (-135)
+8.5 (+100)
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O 38.5 (+100)
U 38.5 (-135)
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In Progress
Troy Trojans
James Madison Dukes
In Progress
TROY
JMAD
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7
16
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+1700
-10000
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+20.5 (+100)
-20.5 (-132)
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O 48.5 (-125)
U 48.5 (-106)
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In Progress
UNLV Rebels
Boise State Broncos
In Progress
UNLV
BOISE
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0
0
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+200
-265
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+6.5 (+102)
-6.5 (-136)
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O 54.5 (-130)
U 54.5 (-102)
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In Progress
North Texas Mean Green
Tulane Green Wave
In Progress
NOTEX
TULANE
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0
0
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-164
+128
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-3.5 (-106)
+3.5 (-125)
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O 63.5 (-132)
U 63.5 (+100)
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Dec 6, 2025 12:00PM EST
Miami Ohio Redhawks
Western Michigan Broncos
12/6/25 12PM
MIAOH
WMICH
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–
–
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-124
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-1.5 (-115)
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O 43.5 (-105)
U 43.5 (-115)
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Dec 6, 2025 12:00PM EST
BYU Cougars
Texas Tech Red Raiders
12/6/25 12PM
BYU
TXTECH
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–
–
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+385
-500
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+12.5 (-110)
-12.5 (-110)
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O 49.5 (-105)
U 49.5 (-115)
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Dec 6, 2025 4:00PM EST
Georgia Bulldogs
Alabama Crimson Tide
12/6/25 4PM
UGA
BAMA
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–
–
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-124
+104
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-2.5 (-105)
+2.5 (-115)
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O 48.5 (-106)
U 48.5 (-114)
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Dec 6, 2025 8:00PM EST
Duke Blue Devils
Virginia Cavaliers
12/6/25 8PM
DUKE
UVA
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–
–
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+152
-180
|
+3.5 (-102)
-3.5 (-120)
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O 57.5 (-115)
U 57.5 (-105)
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Dec 6, 2025 8:00PM EST
Indiana Hoosiers
Ohio State Buckeyes
12/6/25 8PM
IND
OHIOST
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–
–
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+156
-186
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+4.5 (-115)
-4.5 (-105)
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O 46.5 (-114)
U 46.5 (-106)
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Dec 13, 2025 3:00PM EST
Army Black Knights
Navy Midshipmen
12/13/25 3PM
ARMY
NAVY
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–
–
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+172
-210
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+4.5 (-105)
-4.5 (-115)
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O 38.5 (-110)
U 38.5 (-110)
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CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers East Carolina Pirates vs. UTSA Roadrunners on November 22, 2025 at Alamodome.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
| LEAN | %WIN | UNITS | RESULT | |
|---|---|---|---|---|
| COLO@KSTATE | COLO +17.5 | 54.0% | 4 | WIN |
| PSU@RUT | RUT +14 | 52.8% | 1 | WIN |
| OHIOST@MICH | MICH +10.5 | 56.4% | 6 | LOSS |
| VATECH@UVA | VATECH +8 | 57.8% | 7 | LOSS |
| NWEST@ILL | LUKE ALTMYER UNDER 19.5 PASS COMP | 54.3% | 4 | WIN |
| ORE@WAS | DEMOND WILLIAMS JR UNDER 43.5 RUSH YDS | 55.2% | 5 | WIN |
| MIAMI@VATECH | VATECH +18.5 | 54.2% | 4 | WIN |
| GAST@TROY | TROY -9.5 | 55.7% | 5 | WIN |
| DEL@WAKE | DEL +18 | 56.7% | 6 | LOSS |
| NMEX@AF | NMEX -3.5 | 56.1% | 5 | WIN |
| WASHST@JMAD | WASHST +14.5 | 55.3% | 5 | WIN |
| ILL@WISC | WISC +9 | 55.1% | 5 | WIN |
| WKY@LSU | WKY +23.5 | 56.3% | 6 | WIN |
| WASH@UCLA | DEMOND WILLIAMS UNDER 27.5 PASS ATT | 56.3% | 6 | WIN |
| TCU@HOU | AMARE THOMAS OVER 69.5 RECV YDS | 55.2% | 5 | WIN |
| TEX@UGA | NATE FRAZIER UNDER 65.5 RUSH + REC YDS | 55.5% | 5 | WIN |
| PUR@WASH | ANTONIO HARRIS UNDER 73.5 RUSH + REC YDS | 54.1% | 4 | WIN |
| OKLA@BAMA | UNDER 46 | 52.4% | 2 | WIN |
| UVA@DUKE | DUKE -3.5 | 54.7% | 3 | LOSS |
| OKLA@BAMA | BAMA -6 | 54.5% | 3 | LOSS |
| OREGST@TULSA | OREGST -120 | 55.6% | 5 | LOSS |
| UTEP@MIZZST | MIZZST -5 | 54.3% | 4 | WIN |
| COLOST@NMEX | NMEX -14 | 57.1% | 6 | LOSS |
| PSU@MICHST | MICHST +7.5 | 56.5% | 6 | LOSS |
| MISSST@MIZZOU | MISSST +7.5 | 57.2% | 7 | LOSS |
| FAU@TULANE | FAU +17.5 | 56.0% | 6 | WIN |
| NCST@MIAMI | NCST +15.5 | 57.1% | 7 | LOSS |
| KENTST@AKRON | AKRON -6.5 | 55.4% | 5 | LOSS |
| JAXST@UTEP | JAXST -105 | 57.0% | 7 | WIN |
| FSU@CLEM | CLEM -118 | 57.1% | 5 | WIN |
| UNLV@COLOST | UNLV -4 | 55.2% | 5 | WIN |
| OREG@IOWA | IOWA +6.5 | 53.3% | 2 | WIN |
| NEB@UCLA | NEB +1.5 | 55.8% | 5 | WIN |
| KENSAW@NMEXST | NMEXST +10 | 56.5% | 6 | WIN |
| STNFRD@UNC | STNFRD +7.5 | 53.8% | 3 | WIN |
| DUKE@UCONN | UCONN +8.5 | 57.9% | 7 | WIN |
| NEVADA@UTAHST | NEVADA +9.5 | 55.9% | 5 | LOSS |
| SAMST@OREGST | SAMST +21 | 57.7% | 7 | WIN |
| NEB@UCLA | NICO IAMALEAVA UNDER 180.5 PASS YDS | 56.6% | 6 | LOSS |
| HOU@UCF | HOU -112 | 58.0% | 6 | WIN |
| GASTHRN@APPST | GASTHRN +180 | 36.5% | 2 | WIN |
| KENTST@BALLST | BALLST -2.5 | 54.5% | 4 | WIN |
| WAKE@FSU | WAKE +10.5 | 56.4% | 6 | LOSS |
| WYO@SDGST | SDGST -10.5 | 56.7% | 7 | WIN |
| OKLA@TENN | TENN -130 | 58.3% | 5 | LOSS |
| GATECH@NCST | GATECH -5 | 56.4% | 6 | LOSS |
| MIAMI@SMU | MIAMI -10 | 54.3% | 4 | LOSS |
| IND@MD | MD +21.5 | 54.6% | 4 | LOSS |
| CINCY@UTAH | CINCY +11 | 57.6% | 7 | LOSS |
| OLDDOM@LAMON | LAMON +17 | 58.4% | 8 | LOSS |
| VANDY@TEXAS | OVER 46.5 | 53.7% | 2 | WIN |