The November 15, 2025 matchup between the Virginia Tech Hokies and the Florida State Seminoles at Doak Campbell Stadium carries significant weight in the ACC landscape as both programs aim to solidify their postseason positioning late in the season. Florida State, led by head coach Mike Norvell, continues to assert itself as one of the most balanced and dangerous teams in the nation, while Virginia Tech, under Brent Pry, has emerged as a program quietly climbing back toward ACC relevance. The Seminoles’ high-powered offense is again the focal point, now helmed by quarterback D.J. Uiagalelei, whose transfer to Tallahassee has brought experience, efficiency, and poise to Norvell’s fast-paced system. Uiagalelei’s arm strength and ability to extend plays have complemented a deep cast of weapons, including wideouts Hykeem Williams and Destyn Hill, both capable of creating explosive gains after the catch. The ground game, anchored by Trey Benson’s successor, provides Florida State with balance, as the offensive line—one of the ACC’s most experienced units—continues to open lanes while keeping Uiagalelei upright. On defense, coordinator Adam Fuller’s group remains among the most disciplined in the conference, led by defensive end Patrick Payton and linebacker Tatum Bethune. The Seminoles thrive on pressure and physicality, forcing opponents into long-yardage situations and capitalizing on turnovers. Meanwhile, Virginia Tech’s identity has become defined by resilience and defensive toughness. Pry’s defensive-minded background is evident, as the Hokies rank among the ACC’s top units in third-down defense and sacks.

Linebacker Keli Lawson and defensive lineman Antwaun Powell-Ryland have spearheaded a front seven that consistently disrupts opposing quarterbacks, while cornerback Dorian Strong anchors a secondary that has improved its coverage discipline. On offense, quarterback Kyron Drones has grown into a confident dual-threat leader, capable of making big throws on the move while keeping defenses honest with his legs. His connection with wide receiver Da’Quan Felton provides Virginia Tech’s offense with its most reliable big-play outlet, while Bhayshul Tuten leads the backfield as a versatile runner and pass-catcher who excels in open space. The key for the Hokies will be sustaining drives and preventing the game from turning into a track meet—an area where time of possession and efficient third-down execution will be critical. Special teams could play a pivotal role as well, with Florida State’s Ryan Fitzgerald providing consistency in clutch moments and Virginia Tech’s John Love emerging as one of the ACC’s most accurate kickers. Statistically, the edge heavily favors Florida State, particularly at home, where they have covered in seven of their last nine contests and averaged nearly 38 points per game. However, Virginia Tech’s ability to muddy up games with defense and ball control gives them a blueprint for a potential upset if they can win the turnover battle and limit explosive plays. Expect Florida State to dictate tempo early and rely on its superior depth to wear down the Hokies over four quarters. Prediction: Florida State 34, Virginia Tech 17 — the Seminoles’ balanced attack and home-field advantage prove too much for the gritty but still-developing Hokies, as Norvell’s squad keeps its ACC championship aspirations alive in Tallahassee.