Virginia vs Duke Prediction — AI Finds CAN'T MISS CFB Lines & Props (Nov 15)

Updated: 2025-11-08T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Duke Blue Devils host the Virginia Cavaliers on November 15, 2025, in an ACC showdown between two teams aiming to close their seasons on a positive note. Duke enters as a heavy favorite at home behind a balanced offense and disciplined defense, while Virginia looks to play spoiler and snap a late-season skid.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Nov 15, 2025

Start Time: 4:30 PM EST​

Venue: Brooks Field at Wallace Wade Stadium​

Blue Devils Record: (5-4)

Cavaliers Record: (8-2)

OPENING ODDS

UVA Moneyline: +190

DUKE Moneyline: -233

UVA Spread: +6.5

DUKE Spread: -6.5

Over/Under: 57.5

UVA
Betting Trends

  • Virginia has covered in just 3 of its last 9 games, struggling to meet betting expectations, particularly against ranked or defensively strong opponents.

DUKE
Betting Trends

  • Duke has been one of the more reliable ACC teams at home, covering the spread in 6 of its last 8 home contests thanks to a resilient defense and efficient quarterback play.

MATCHUP TRENDS

  • Historically, Duke has covered the spread in four of the last five matchups against Virginia, often capitalizing on turnovers and second-half adjustments. With Duke’s improved scoring defense and Virginia’s inconsistent offense, the odds lean toward another Blue Devils cover.

UVA vs. DUKE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup:

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Virginia vs Duke Prediction & Odds:
Free CFB Betting Insights for 11/15/25

The November 15, 2025 ACC showdown between the Virginia Cavaliers and the Duke Blue Devils at Wallace Wade Stadium in Durham brings together two programs heading in opposite directions, with Duke surging toward another bowl appearance and Virginia still searching for stability under Tony Elliott. Duke, led by head coach Manny Diaz, has built a reputation this season as one of the most fundamentally sound and well-rounded teams in the ACC, boasting a 7-3 record entering the contest. Their identity is defined by balance — a disciplined defense that allows just 20.2 points per game and an offense that scores over 31 points per contest. Quarterback Maalik Murphy has been a revelation, seamlessly transitioning into Duke’s system with composure and precision, throwing for over 2,400 yards and 18 touchdowns while maintaining one of the lowest interception rates in the conference. He’s complemented by a deep backfield led by Jordan Waters, who’s rushed for nearly 1,000 yards and 10 touchdowns, while Jaquez Moore adds an explosive element on outside runs and passing plays. Duke’s offensive line, anchored by veterans Graham Barton and Maurice McIntyre, has provided outstanding protection and has been the cornerstone of their success. Wideouts Jalon Calhoun and Sahmir Hagans have emerged as reliable targets, combining for more than 1,200 receiving yards and showcasing strong chemistry with Murphy. The Blue Devils’ defense has been just as formidable, ranking among the ACC’s best in takeaways and red-zone efficiency. Linebacker Tre Freeman leads the team in tackles, and defensive lineman DeWayne Carter continues to wreak havoc in the trenches, while safety Jaylen Stinson’s coverage and physicality make the secondary one of Duke’s biggest strengths. Virginia, meanwhile, enters at 3-7 and continues to struggle with consistency, though flashes of promise have come from young quarterback Anthony Colandrea, who’s thrown for over 2,000 yards with 13 touchdowns but has also tossed 10 interceptions.

The Cavaliers’ offense averages 23 points per game but has been held under 20 in five contests due to an inconsistent offensive line and red-zone inefficiency. Running back Perris Jones, returning from injury, has been a bright spot, rushing for over 500 yards at a solid clip, while wideouts Malik Washington and Malachi Fields give Virginia a legitimate one-two punch in the passing game. Defensively, the Cavaliers have not been able to stop the run, giving up 180 yards per game on the ground and allowing opponents to sustain long drives that wear down their front seven. Linebackers Kam Robinson and James Jackson have played well, but the unit’s lack of depth and pass-rush pressure has left the secondary vulnerable to big plays. Against a balanced Duke offense that thrives on controlling time of possession and converting third downs, Virginia faces a daunting task. The key matchup will be Virginia’s secondary versus Duke’s efficient passing attack; if the Cavaliers can’t disrupt Murphy’s rhythm, the game could slip away early. Betting trends reinforce this divide — Duke has covered the spread in six of its last eight home games, while Virginia has covered in only three of its last nine overall. The Blue Devils’ dominance at home, combined with Virginia’s inconsistency on the road, makes this a difficult spot for the Cavaliers to generate an upset. Expect Duke to assert control early, using its physical line play and disciplined defense to set the tone. Virginia might stay competitive in the first half, but Duke’s depth, execution, and home-field advantage should prevail decisively. Prediction: Duke 34, Virginia 17, with the Blue Devils cruising to another convincing victory and strengthening their bowl positioning in the ACC standings.

Virginia Cavaliers CFB Preview

The Virginia Cavaliers travel to Durham to take on the Duke Blue Devils on November 15, 2025, hoping to play spoiler and end their season on a positive note after another year marked by inconsistency and growing pains. Under head coach Tony Elliott, Virginia sits at 3-7, a record that reflects flashes of competitiveness mixed with long stretches of frustration. Offensively, the Cavaliers have shown moments of progress behind sophomore quarterback Anthony Colandrea, whose arm strength and athleticism give the offense a spark. Colandrea has thrown for more than 2,000 yards and 13 touchdowns but has also committed 10 interceptions, a product of both youth and a lack of consistent pass protection. The offensive line has struggled all season, allowing steady pressure and limiting the ability to stretch the field vertically. Running back Perris Jones has been a bright spot since returning from injury, rushing for over 500 yards at an average of 4.7 yards per carry, providing some balance to an offense that averages just over 23 points per game. Wide receivers Malik Washington and Malachi Fields have been the driving forces in the passing game, combining for more than 1,500 yards and offering reliable targets who can move the chains. However, sustaining drives has been a recurring issue; Virginia converts only about 35% of its third-down attempts and struggles to finish possessions in the red zone, leading to missed scoring opportunities that have cost them several close games. Defensively, the Cavaliers have been unable to find consistency. They allow nearly 31 points per game and have struggled to stop the run, giving up close to 180 rushing yards per contest. The front seven, led by linebackers Kam Robinson and James Jackson, has talent but often wears down as the game progresses due to lack of depth and time of possession deficits.

Their pass rush, with just 17 sacks on the season, ranks near the bottom of the ACC, which could be problematic against a disciplined Duke offensive line that has allowed few pressures all year. In the secondary, cornerback Dre Walker and safety Jonas Sanker have shown improvement, but coverage breakdowns and missed tackles remain persistent problems. To stay competitive in this matchup, Virginia will need to play a nearly perfect game — control the ball, win the turnover battle, and limit Duke’s explosive plays. Offensively, Elliott will likely look to use short passes, screens, and quarterback rollouts to mitigate pressure and create manageable down-and-distance situations. Defensively, Virginia must prioritize stopping Duke’s ground game early, forcing quarterback Maalik Murphy into third-and-long scenarios where they can pressure him into mistakes. Special teams will also be critical; kicker Will Bettridge has been dependable, but inconsistent punting and coverage could put Virginia at a field-position disadvantage. Historically, Virginia has had difficulty on the road, covering the spread in just three of its last nine games, and that trend reflects their inability to finish games in hostile environments. Still, the Cavaliers are a scrappy, prideful group that plays hard even when outmatched. Their best hope lies in starting fast and catching Duke off guard with aggressive play-calling early, perhaps generating momentum through turnovers or special-teams plays. If Colandrea can protect the football and Washington and Fields can find openings in Duke’s disciplined secondary, Virginia could keep the game within reach for a half. However, the combination of Duke’s home-field advantage, superior defense, and offensive efficiency will likely wear the Cavaliers down over four quarters. Expect Virginia to compete with heart but ultimately fall short against a deeper, more polished opponent. Prediction: Duke 34, Virginia 17, as the Cavaliers’ effort isn’t enough to overcome their execution issues and defensive shortcomings.

The Duke Blue Devils host the Virginia Cavaliers on November 15, 2025, in an ACC showdown between two teams aiming to close their seasons on a positive note. Duke enters as a heavy favorite at home behind a balanced offense and disciplined defense, while Virginia looks to play spoiler and snap a late-season skid. Virginia vs Duke AI Prediction: Free CFB Betting Insights for Nov 15. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Duke Blue Devils CFB Preview

The Duke Blue Devils return to Wallace Wade Stadium on November 15, 2025, in control of their own postseason destiny, entering this matchup against the Virginia Cavaliers with a 7-3 record and one of the most balanced teams in the ACC. Under head coach Manny Diaz, Duke has continued its transformation into a program defined by physicality, defensive discipline, and offensive balance. The Blue Devils’ formula for success this season has been simple yet effective — dominate the trenches, win time of possession, and capitalize on opponents’ mistakes. Offensively, Duke averages around 31 points per game, led by quarterback Maalik Murphy, who has displayed maturity beyond his years. Murphy has thrown for over 2,400 yards and 18 touchdowns while maintaining one of the lowest interception rates in the conference, proving himself capable of both stretching defenses vertically and managing tempo efficiently. He benefits from a strong supporting cast that includes running back Jordan Waters, who’s rushed for nearly 1,000 yards and 10 touchdowns, and Jaquez Moore, whose burst and versatility provide an ideal complement. The offensive line, anchored by Graham Barton and Maurice McIntyre, has been dominant in both pass protection and run blocking, giving Duke the consistency needed to sustain long drives. Wideouts Jalon Calhoun and Sahmir Hagans lead a deep receiver group that thrives on timing routes and yards after the catch, helping Duke maintain balance and unpredictability. Defensively, the Blue Devils have been one of the ACC’s most formidable units, allowing just 20.2 points per game and excelling in both red-zone defense and third-down efficiency. Linebacker Tre Freeman has emerged as the heart of the defense with his tackling and leadership, while defensive lineman DeWayne Carter continues to set the tone up front, combining power and quickness to disrupt plays in the backfield.

The secondary, featuring standout safety Jaylen Stinson and cornerback Chandler Rivers, has excelled at limiting big plays and forcing turnovers, ranking among the ACC’s leaders in interceptions. Duke’s defensive identity is built on gap integrity and discipline — they rarely beat themselves with penalties or blown coverages, and they thrive in high-leverage moments. The Blue Devils’ special teams have also played a crucial role in their success, with kicker Todd Pelino proving reliable inside 45 yards and the return units consistently flipping field position. At home, Duke has been particularly dominant, covering the spread in six of its last eight home games and holding opponents to under 17 points per contest on average. The key for Duke in this matchup will be maintaining focus and avoiding complacency against a Virginia team that, while struggling, has playmakers capable of striking quickly if given opportunities. Expect the Blue Devils to lean heavily on their rushing attack early, using Waters and Moore to control tempo and wear down Virginia’s defensive front, which has allowed nearly 180 rushing yards per game. Murphy will look to build on that foundation with efficient play-action passing, targeting Calhoun and Hagans against a vulnerable Cavalier secondary that has struggled to contain big plays. Defensively, Duke’s goal will be to pressure Virginia quarterback Anthony Colandrea into mistakes, as turnovers have plagued the Cavaliers all season. With superior depth, coaching, and execution, Duke has all the advantages necessary to take command early and maintain control throughout. A balanced offensive effort paired with another stout defensive performance should keep the Blue Devils in complete control as they close in on another bowl berth. Prediction: Duke 34, Virginia 17, as Duke’s discipline, balance, and home-field dominance once again prove too much for a struggling opponent.

Virginia vs. Duke Prop Picks (AI)

AI algorithm Remi is pouring through mountains of data on each line. In fact, anytime the Cavaliers and Blue Devils play there’s always several intriguing angles to key in on. Not to mention games played at Brooks Field at Wallace Wade Stadium in Nov almost always follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup:

Virginia vs. Duke Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over mountains of data from every angle between the Cavaliers and Blue Devils and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.

The Algorithm has been most watching on the unproportionally assigned factor knucklehead sportsbettors often put on player performance factors between a Cavaliers team going up against a possibly improved Blue Devils team. Trends look to say the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Virginia vs Duke picks, computer picks Cavaliers vs Blue Devils, best bets, model edges, confidence ratings.

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Cavaliers Betting Trends

Virginia has covered in just 3 of its last 9 games, struggling to meet betting expectations, particularly against ranked or defensively strong opponents.

Blue Devils Betting Trends

Duke has been one of the more reliable ACC teams at home, covering the spread in 6 of its last 8 home contests thanks to a resilient defense and efficient quarterback play.

Cavaliers vs. Blue Devils Matchup Trends

Historically, Duke has covered the spread in four of the last five matchups against Virginia, often capitalizing on turnovers and second-half adjustments. With Duke’s improved scoring defense and Virginia’s inconsistent offense, the odds lean toward another Blue Devils cover.

Virginia vs. Duke Game Info

Virginia vs Duke starts on November 15, 2025 at 4:30 PM EST.

Venue: Brooks Field at Wallace Wade Stadium.

Spread: Duke -6.5
Moneyline: Virginia +190, Duke -233
Over/Under: 57.5

Virginia: (8-2)  |  Duke: (5-4)

Remi's searched hard and found the best prop for this matchup:. Prices move—always shop for the best number.

Historically, Duke has covered the spread in four of the last five matchups against Virginia, often capitalizing on turnovers and second-half adjustments. With Duke’s improved scoring defense and Virginia’s inconsistent offense, the odds lean toward another Blue Devils cover.

UVA trend: Virginia has covered in just 3 of its last 9 games, struggling to meet betting expectations, particularly against ranked or defensively strong opponents.

DUKE trend: Duke has been one of the more reliable ACC teams at home, covering the spread in 6 of its last 8 home contests thanks to a resilient defense and efficient quarterback play.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Virginia vs. Duke Odds

Remi is pouring through tons of stats on each player. In fact, anytime the Virginia vs Duke trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable patterns.

Virginia vs Duke Opening Odds

UVA Moneyline: +190
DUKE Moneyline: -233
UVA Spread: +6.5
DUKE Spread: -6.5
Over/Under: 57.5

Virginia vs Duke Live Odds

Games PTS ML SPR O/U
Nov 12, 2025 7:00PM EST
Northern Illinois Huskies
Umass Minutemen
11/12/25 7PM
NILL
UMASS
-420
 
-10.5 (-110)
 
O 43.5 (-110)
U 43.5 (-110)
Nov 12, 2025 7:00PM EST
Buffalo Bulls
Central Michigan Chippewas
11/12/25 7PM
BUFF
CMICH
+104
-122
+1.5 (-105)
-1.5 (-115)
O 44.5 (-110)
U 44.5 (-110)
Nov 12, 2025 7:00PM EST
Toledo Rockets
Miami Ohio Redhawks
11/12/25 7PM
TOLEDO
MIAOH
-190
 
-4.5 (-106)
 
O 45.5 (-105)
U 45.5 (-115)
Nov 13, 2025 7:30PM EST
Troy Trojans
Old Dominion Monarchs
11/13/25 7:30PM
TROY
OLDDOM
+350
-450
+10.5 (-105)
-10.5 (-115)
O 52.5 (-105)
U 52.5 (-115)
Nov 14, 2025 7:30PM EST
Clemson Tigers
Louisville Cardinals
11/14/25 7:30PM
CLEM
LVILLE
+120
-142
+2.5 (-102)
-2.5 (-120)
O 51.5 (-105)
U 51.5 (-115)
Nov 14, 2025 9:00PM EST
Minnesota Golden Gophers
Oregon Ducks
11/14/25 9PM
MINN
OREG
+1600
-4500
+25.5 (-115)
-25.5 (-105)
O 44.5 (-110)
U 44.5 (-110)
Nov 15, 2025 12:00PM EST
Air Force Falcons
UConn Huskies
11/15/25 12PM
AF
UCONN
+225
-275
+7.5 (-120)
-7.5 (-102)
O 63.5 (-110)
U 63.5 (-110)
Nov 15, 2025 12:00PM EST
Michigan Wolverines
Northwestern Wildcats
11/15/25 12PM
MICH
NWEST
-550
+410
-12.5 (-106)
+12.5 (-114)
O 41.5 (-105)
U 41.5 (-115)
Nov 15, 2025 12:00PM EST
UTSA Roadrunners
Charlotte 49ers
11/15/25 12PM
UTSA
CHARLO
-1200
+750
-18.5 (-110)
+18.5 (-110)
O 59.5 (-110)
U 59.5 (-110)
Nov 15, 2025 12:00PM EST
South Florida Bulls
Navy Midshipmen
11/15/25 12PM
SFLA
NAVY
-430
+340
-10.5 (-110)
+10.5 (-110)
O 64.5 (-115)
U 64.5 (-105)
Nov 15, 2025 12:00PM EST
Arizona Wildcats
Cincinnati Bearcats
11/15/25 12PM
ARIZ
CINCY
+184
-220
+6.5 (-115)
-6.5 (-105)
O 56.5 (-110)
U 56.5 (-110)
Nov 15, 2025 12:00PM EST
Eastern Michigan Eagles
Ball State Cardinals
11/15/25 12PM
EMICH
BALLST
-130
+110
-2.5 (-110)
+2.5 (-110)
O 50.5 (-105)
U 50.5 (-115)
Nov 15, 2025 12:00PM EST
Notre Dame Fighting Irish
Pittsburgh Panthers
11/15/25 12PM
ND
PITT
-490
+380
-11.5 (-114)
+11.5 (-106)
O 55.5 (-108)
U 55.5 (-112)
Nov 15, 2025 12:00PM EST
South Carolina Gamecocks
Texas A&M Aggies
11/15/25 12PM
SC
TEXAM
+870
-1500
+18.5 (-105)
-18.5 (-115)
O 48.5 (-110)
U 48.5 (-110)
Nov 15, 2025 12:00PM EST
Wisconsin Badgers
Indiana Hoosiers
11/15/25 12PM
WISC
IND
+2200
-10000
+29.5 (-110)
-29.5 (-110)
O 43.5 (-115)
U 43.5 (-105)
Nov 15, 2025 12:00PM EST
Kansas State Wildcats
Oklahoma State Cowboys
11/15/25 12PM
KSTATE
OKLAST
-1500
+870
-19.5 (-115)
+19.5 (-105)
O 52.5 (-110)
U 52.5 (-110)
Nov 15, 2025 12:45PM EST
Arkansas Razorbacks
LSU Tigers
11/15/25 12:45PM
ARK
LSU
+180
-215
+5.5 (-105)
-5.5 (-115)
O 56.5 (-110)
U 56.5 (-110)
Nov 15, 2025 1:00PM EST
Oregon State Beavers
Tulsa Golden Hurricane
11/15/25 1PM
OREGST
TULSA
-136
+116
-2.5 (-114)
+2.5 (-106)
O 48.5 (-110)
U 48.5 (-110)
Nov 15, 2025 1:00PM EST
West Virginia Mountaineers
Arizona State Sun Devils
11/15/25 1PM
WVU
ARIZST
+360
-460
+11.5 (-115)
-11.5 (-105)
O 48.5 (-105)
U 48.5 (-115)
Nov 15, 2025 1:30PM EST
Tennessee Tech Golden Eagles
Kentucky Wildcats
11/15/25 1:30PM
TNTECH
UK
+900
-1600
+20.5 (-115)
-20.5 (-105)
O 52.5 (-105)
U 52.5 (-115)
Nov 15, 2025 2:00PM EST
Marshall Thundering Herd
Georgia State Panthers
11/15/25 2PM
MARSH
GAST
-300
+245
-7.5 (-106)
+7.5 (-114)
O 64.5 (-110)
U 64.5 (-110)
Nov 15, 2025 2:00PM EST
North Texas Mean Green
UAB Blazers
11/15/25 2PM
NOTEX
UAB
-1350
+810
-18.5 (-110)
+18.5 (-110)
O 70.5 (-105)
U 70.5 (-115)
Nov 15, 2025 3:00PM EST
UTEP Miners
Missouri State Bears
11/15/25 3PM
UTEP
MIZZST
+152
-180
+4.5 (-115)
-4.5 (-105)
O 49.5 (-110)
U 49.5 (-110)
Nov 15, 2025 3:00PM EST
Colorado State Rams
New Mexico Lobos
11/15/25 3PM
COLOST
NMEX
+500
-700
+14.5 (-110)
-14.5 (-110)
O 53.5 (-110)
U 53.5 (-110)
Nov 15, 2025 3:30PM EST
San Jose State Spartans
Nevada Wolf Pack
11/15/25 3:30PM
SJST
NEVADA
-335
+270
-9.5 (-108)
+9.5 (-112)
O 52.5 (-106)
U 52.5 (-114)
Nov 15, 2025 3:30PM EST
South Alabama Jaguars
UL Monroe Warhawks
11/15/25 3:30PM
SBAMA
MONROE
-198
+166
-4.5 (-110)
+4.5 (-110)
O 51.5 (-105)
U 51.5 (-115)
Nov 15, 2025 3:30PM EST
UCF Knights
Texas Tech Red Raiders
11/15/25 3:30PM
UCF
TXTECH
+1400
-3500
+23.5 (-102)
-23.5 (-120)
O 47.5 (-115)
U 47.5 (-105)
Nov 15, 2025 3:30PM EST
NC State Wolfpack
Miami Hurricanes
11/15/25 3:30PM
NCST
MIAMI
+460
-620
+14.5 (-110)
-14.5 (-110)
O 55.5 (-110)
U 55.5 (-110)
Nov 15, 2025 3:30PM EST
Maryland Terrapins
Illinois Fighting Illini
11/15/25 3:30PM
MD
ILL
+530
-750
+14.5 (-110)
-14.5 (-110)
O 53.5 (-110)
U 53.5 (-110)
Nov 15, 2025 3:30PM EST
Georgia Tech Yellow Jackets
Boston College Eagles
11/15/25 3:30PM
GATECH
BC
-900
+610
-16.5 (-115)
+16.5 (-105)
O 58.5 (-115)
U 58.5 (-105)
Nov 15, 2025 3:30PM EST
Penn State Nittany Lions
Michigan State Spartans
11/15/25 3:30PM
PSU
MICHST
-290
+235
-7.5 (-106)
+7.5 (-114)
O 48.5 (-114)
U 48.5 (-106)
Nov 15, 2025 3:30PM EST
MTSU Blue Raiders
Western Kentucky Hilltoppers
11/15/25 3:30PM
MTSU
WKY
 
-550
 
-13.5 (-110)
O 55.5 (-110)
U 55.5 (-110)
Nov 15, 2025 3:30PM EST
Virginia Cavaliers
Duke Blue Devils
11/15/25 3:30PM
UVA
DUKE
+144
-172
+4.5 (-115)
-4.5 (-105)
O 58.5 (-110)
U 58.5 (-110)
Nov 15, 2025 3:30PM EST
Iowa Hawkeyes
USC Trojans
11/15/25 3:30PM
IOWA
USC
+215
-260
+6.5 (+100)
-6.5 (-122)
O 49.5 (-110)
U 49.5 (-110)
Nov 15, 2025 3:30PM EST
App State Mountaineers
James Madison Dukes
11/15/25 3:30PM
APPST
JMAD
 
-1600
 
-21.5 (-102)
O 53.5 (-115)
U 53.5 (-105)
Nov 15, 2025 3:30PM EST
Texas State Bobcats
USM Golden Eagles
11/15/25 3:30PM
TEXST
USM
+150
 
+4.5 (-114)
 
O 65.5 (-115)
U 65.5 (-105)
Nov 15, 2025 3:30PM EST
Oklahoma Sooners
Alabama Crimson Tide
11/15/25 3:30PM
OKLA
BAMA
+172
-205
+5.5 (-105)
-5.5 (-115)
O 46.5 (-105)
U 46.5 (-115)
Nov 15, 2025 4:00PM EST
Florida Atlantic Owls
Tulane Green Wave
11/15/25 4PM
FAU
TULANE
+610
-900
+17.5 (-110)
-17.5 (-110)
O 63.5 (-110)
U 63.5 (-110)
Nov 15, 2025 4:00PM EST
Memphis Tigers
East Carolina Pirates
11/15/25 4PM
MEMP
ECAR
+120
-142
+2.5 (-105)
-2.5 (-115)
O 58.5 (-110)
U 58.5 (-110)
Nov 15, 2025 4:15PM EST
New Mexico State Aggies
Tennessee Volunteers
11/15/25 4:15PM
NMEXST
TENN
+8000
-50000
+40.5 (-110)
-40.5 (-110)
O 61.5 (-115)
U 61.5 (-105)
Nov 15, 2025 4:30PM EST
North Carolina Tar Heels
Wake Forest Demon Deacons
11/15/25 4:30PM
UNC
WAKE
+188
-225
+6.5 (-115)
-6.5 (-105)
O 38.5 (-110)
U 38.5 (-110)
Nov 15, 2025 5:00PM EST
Liberty Flames
FIU Panthers
11/15/25 5PM
LIB
FIU
-146
 
-2.5 (-120)
 
O 51.5 (-115)
U 51.5 (-105)
Nov 15, 2025 6:00PM EST
Coastal Carolina Chanticleers
Georgia Southern Eagles
11/15/25 6PM
COAST
GASO
+122
-146
+2.5 (+100)
-2.5 (-122)
O 60.5 (-110)
U 60.5 (-110)
Nov 15, 2025 7:00PM EST
Utah State Aggies
UNLV Rebels
11/15/25 7PM
UTAHST
UNLV
+184
-225
+6.5 (-115)
-6.5 (-105)
O 71.5 (-105)
U 71.5 (-115)
Nov 15, 2025 7:00PM EST
Florida Gators
Ole Miss Rebels
11/15/25 7PM
FLA
OLEMISS
+480
-690
+14.5 (-110)
-14.5 (-110)
O 53.5 (-115)
U 53.5 (-105)
Nov 15, 2025 7:00PM EST
Delaware Blue Hens
Sam Houston State Bearkats
11/15/25 7PM
DEL
SAMST
-375
+290
-9.5 (-114)
+9.5 (-106)
O 56.5 (-110)
U 56.5 (-110)
Nov 15, 2025 7:00PM EST
Utah Utes
Baylor Bears
11/15/25 7PM
UTAH
BAYLOR
-330
+260
-8.5 (-110)
+8.5 (-110)
O 60.5 (-108)
U 60.5 (-112)
Nov 15, 2025 7:00PM EST
Purdue Boilermakers
Washington Huskies
11/15/25 7PM
PURDUE
WASH
+610
-950
+16.5 (-108)
-16.5 (-112)
O 53.5 (-110)
U 53.5 (-110)
Nov 15, 2025 7:30PM EST
Virginia Tech Hokies
Florida State Seminoles
11/15/25 7:30PM
VATECH
FSU
+430
-600
+13.5 (-105)
-13.5 (-115)
O 54.5 (-110)
U 54.5 (-110)
Nov 15, 2025 7:30PM EST
Texas Longhorns
Georgia Bulldogs
11/15/25 7:30PM
TEXAS
UGA
+164
-200
+5.5 (-110)
-5.5 (-110)
O 48.5 (-104)
U 48.5 (-118)
Nov 15, 2025 7:30PM EST
UCLA Bruins
Ohio State Buckeyes
11/15/25 7:30PM
UCLA
OHIOST
+4000
-30000
+32.5 (-110)
-32.5 (-110)
O 48.5 (-110)
U 48.5 (-110)
Nov 15, 2025 7:45PM EST
Mississippi State Bulldogs
Missouri Tigers
11/15/25 7:45PM
MISSST
MIZZOU
+230
-285
+7.5 (-122)
-7.5 (+100)
O 51.5 (-110)
U 51.5 (-110)
Nov 15, 2025 8:00PM EST
Kennesaw State Owls
Jacksonville State Gamecocks
11/15/25 8PM
KENSAW
JAXST
-156
+130
-3.5 (-104)
+3.5 (-118)
O 54.5 (-110)
U 54.5 (-110)
Nov 15, 2025 10:00PM EST
Louisiana Tech Bulldogs
Washington State Cougars
11/15/25 10PM
LATECH
WASHST
+255
-320
+7.5 (-104)
-7.5 (-118)
O 44.5 (-110)
U 44.5 (-110)
Nov 15, 2025 10:15PM EST
TCU Horned Frogs
BYU Cougars
11/15/25 10:15PM
TCU
BYU
+158
-192
+5.5 (-114)
-5.5 (-106)
O 52.5 (-110)
U 52.5 (-110)
Nov 15, 2025 10:30PM EST
Boise State Broncos
San Diego State Aztecs
11/15/25 10:30PM
BOISE
SDGST
+118
-142
+2.5 (+100)
-2.5 (-122)
O 41.5 (-104)
U 41.5 (-118)
Nov 15, 2025 10:30PM EST
Wyoming Cowboys
Fresno State Bulldogs
11/15/25 10:30PM
WYO
FRESNO
+140
-170
+3.5 (-110)
-3.5 (-110)
O 40.5 (-110)
U 40.5 (-110)
Nov 22, 2025 12:00PM EST
USC Trojans
Oregon Ducks
11/22/25 12PM
USC
OREG
+176
-215
+6.5 (-115)
-6.5 (-105)
O 55.5 (-105)
U 55.5 (-115)
Nov 22, 2025 12:00PM EST
Pittsburgh Panthers
Georgia Tech Yellow Jackets
11/22/25 12PM
PITT
GATECH
+136
-164
+3.5 (-115)
-3.5 (-105)
O 58.5 (-115)
U 58.5 (-105)
Dec 6, 2025 8:00PM EST
Ohio State Buckeyes
Indiana Hoosiers
12/6/25 8PM
OHIOST
IND
-225
+180
-5.5 (-122)
+5.5 (+100)
O 49.5 (-110)
U 49.5 (-110)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Virginia Cavaliers vs. Duke Blue Devils on November 15, 2025 at Brooks Field at Wallace Wade Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
JAXST@UTEP JAXST -105 57.0% 7 WIN
FSU@CLEM CLEM -118 57.1% 5 WIN
UNLV@COLOST UNLV -4 55.2% 5 WIN
OREG@IOWA IOWA +6.5 53.3% 2 WIN
NEB@UCLA NEB +1.5 55.8% 5 WIN
AUBURN@VANDY AUBURN +6.5 56.2% 6 LOSS
KENSAW@NMEXST NMEXST +10 56.5% 6 WIN
STNFRD@UNC STNFRD +7.5 53.8% 3 WIN
DUKE@UCONN UCONN +8.5 57.9% 7 WIN
NEVADA@UTAHST NEVADA +9.5 55.9% 5 LOSS
SAMST@OREGST SAMST +21 57.7% 7 WIN
NEB@UCLA NICO IAMALEAVA UNDER 180.5 PASS YDS 56.6% 6 LOSS
HOU@UCF HOU -112 58.0% 6 WIN
GASTHRN@APPST GASTHRN +180 36.5% 2 WIN
KENTST@BALLST BALLST -2.5 54.5% 4 WIN
WAKE@FSU WAKE +10.5 56.4% 6 LOSS
WYO@SDGST SDGST -10.5 56.7% 7 WIN
OKLA@TENN TENN -130 58.3% 5 LOSS
GATECH@NCST GATECH -5 56.4% 6 LOSS
MIAMI@SMU MIAMI -10 54.3% 4 LOSS
DEL@LIB DEL +3.5 57.6% 7 LOSS
NMEXST@WKY NMEXST +8.5 57.9% 7 LOSS
IND@MD MD +21.5 54.6% 4 LOSS
CINCY@UTAH CINCY +11 57.6% 7 LOSS
OLDDOM@LAMON LAMON +17 58.4% 8 LOSS
VANDY@TEXAS OVER 46.5 53.7% 2 WIN
MICHST@MINN MAKHI FRAZIER UNDER 52.5 RUSH YDS 55.2% 5 WIN
UNC@CUSE UNC +110 50.4% 2 WIN
MRSHL@COASTAL COASTAL +7 53.3% 3 WIN
FIU@MIZZST FIU +3.5 53.9% 3 LOSS
TEXAM@LSU MARCEL REED OVER 0.5 INT 55.5% 5 WIN
RUT@PURDUE RUT +103 54.0% 4 WIN
TOLEDO@WASHST TOLEDO -110 56.1% 6 LOSS
AUBURN@ARK ARK -128 60.5% 8 LOSS
NCST@PITT NCST +6.5 54.9% 4 LOSS
OHIO@EMICH EMICH +12 54.1% 4 WIN
TCU@WVU WVU +16.5 54.6% 4 WIN
COLO@UTAH COLO +14.5 57.7% 7 LOSS
HOU@ARIZST HOU +7.5 57.1% 7 WIN
UVA@UNC UNC +11.5 56.2% 6 WIN
MINN@IOWA MINN +9.5 57.3% 7 LOSS
UCONN@RICE RICE +10.5 57.1% 6 WIN
FAU@NAVY FAU +14.5 56.7% 6 WIN
LAMON@USM LAMON +13.5 56.4% 6 LOSS
BOISE@NEVADA NEVADA +21.5 56.8% 6 WIN
SALA@GAST GAST +6.5 54.3% 4 LOSS
MIZZST@NMEXST MIZZST -108 54.4% 4 WIN
KENSAW@FIU FIU +3 53.7% 3 LOSS
KENTST@TOLEDO KENTST +24.5 56.9% 6 LOSS
OLDDOM@JMAD JMAD -125 57.9% 7 WIN
TXTECH@ARIZST TXTECH -6.5 54.2% 4 LOSS