Nittany Lions vs. Buckeyes
Prediction, Odds & Props
Nov 01 | CFB AI Picks
Updated: 2025-10-25T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Nov 01, 2025
Start Time: ​
Venue: ​
Buckeyes Record:
Nittany Lions Record:
OPENING ODDS
PSU Moneyline:
OHIOST Moneyline:
PSU Spread:
OHIOST Spread:
Over/Under:
PSU
Betting Trends
OHIOST
Betting Trends
MATCHUP TRENDS
PSU vs. OHIOST
Best Prop Bet
LIVE CFB ODDS
CFB ODDS COMPARISON
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Penn State vs Ohio State Prediction & Odds:
Free CFB Betting Insights for 11/1/25
Penn State Nittany Lions CFB Preview
Credit: USA TODAY/IMAGN
Ohio State Buckeyes CFB Preview
Penn State vs. Ohio State Prop Picks (AI)
AI algorithm Remi is pouring through loads of data on each team. In fact, anytime the Nittany Lions and Buckeyes play there’s always several intriguing trends to key in on. Not to mention games played at in Nov almost always follow normal, predictable betting trends.
Penn State vs. Ohio State Prediction (AI)
Remi, our AI sports algorithm, has been pouring over mountains of data from every past game between the Nittany Lions and Buckeyes and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.
Interestingly enough, the data has been most watching on the linear correlation of weight human bettors often put on player performance factors between a Nittany Lions team going up against a possibly strong Buckeyes team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Penn State vs Ohio State picks, computer picks Nittany Lions vs Buckeyes, best bets, model edges, confidence ratings.
 |
DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.Â
Nittany Lions Betting Trends
Buckeyes Betting Trends
Nittany Lions vs. Buckeyes Matchup Trends
Penn State vs. Ohio State Game Info
What time does Penn State vs Ohio State start on November 01, 2025?
Penn State vs Ohio State starts on November 01, 2025 at .
What are the opening odds for Penn State vs Ohio State?
Spread: Ohio State
Moneyline: Penn State , Ohio State
Over/Under:
What are the records for Penn State vs Ohio State?
Penn State: Â |Â Ohio State:
What is the AI best bet for Penn State vs Ohio State?
. Prices move—always shop for the best number.
What are Penn State trending bets?
PSU trend:
What are Ohio State trending bets?
OHIOST trend:
Where can I find AI Picks for Penn State vs Ohio State?
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
Penn State vs. Ohio State Odds
AI algorithm Remi is pouring through tons of data points on each team. In fact, anytime the Penn State vs Ohio State trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable betting trends.
Penn State vs Ohio State Opening Odds
PSU Moneyline:
OHIOST Moneyline:
PSU Spread:
OHIOST Spread:
Over/Under:
Penn State vs Ohio State Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Oct 2, 2025 9:00PM EDT
Sam Houston State Bearkats
New Mexico State Aggies
10/2/25 9PM
SAMST
NMEXST
|
–
–
|
-138
+113
|
-2.5 (-110)
+2.5 (-110)
|
O 52.5 (-110)
U 52.5 (-110)
|
|
|
Oct 3, 2025 7:00PM EDT
Western Kentucky Hilltoppers
Delaware Blue Hens
10/3/25 7PM
WKY
DEL
|
–
–
|
+123
-151
|
+2.5 (-101)
-2.5 (-111)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
|
Oct 3, 2025 7:00PM EDT
Charlotte 49ers
South Florida Bulls
10/3/25 7PM
CHARLO
SFLA
|
–
–
|
+1290
-5049
|
+27 (-110)
-27 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
|
Oct 3, 2025 10:00PM EDT
New Mexico Lobos
San Jose State Spartans
10/3/25 10PM
NMEX
SJST
|
–
–
|
+113
-138
|
+2.5 (-110)
-2.5 (-110)
|
O 58.5 (-110)
U 58.5 (-110)
|
|
|
Oct 3, 2025 10:30PM EDT
Colorado State Rams
San Diego State Aztecs
10/3/25 10:30PM
COLOST
SDGST
|
–
–
|
+208
-265
|
+6 (-110)
-6 (-110)
|
O 40.5 (-110)
U 40.5 (-110)
|
|
|
Oct 3, 2025 10:30PM EDT
West Virginia Mountaineers
BYU Cougars
10/3/25 10:30PM
WVU
BYU
|
–
–
|
+760
-1408
|
+19 (-110)
-19 (-110)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Ohio Bobcats
Ball State Cardinals
10/4/25 12PM
OHIO
BALLST
|
–
–
|
-661
+461
|
-14.5 (-110)
+14.5 (-110)
|
O 51 (-110)
U 51 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Illinois Fighting Illini
Purdue Boilermakers
10/4/25 12PM
ILL
PURDUE
|
–
–
|
-370
+285
|
-10 (-110)
+10 (-110)
|
O 57 (-110)
U 57 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Kansas State Wildcats
Baylor Bears
10/4/25 12PM
KSTATE
BAYLOR
|
–
–
|
+196
-248
|
+6.5 (-110)
-6.5 (-110)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Kentucky Wildcats
Georgia Bulldogs
10/4/25 12PM
UK
UGA
|
–
–
|
+820
-1587
|
+20.5 (-110)
-20.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Clemson Tigers
North Carolina Tar Heels
10/4/25 12PM
CLEM
UNC
|
–
–
|
-652
+456
|
-14 (-110)
+14 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Wisconsin Badgers
Michigan Wolverines
10/4/25 12PM
WISC
MICH
|
–
–
|
+631
-1087
|
+17.5 (-110)
-17.5 (-110)
|
O 43 (-110)
U 43 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Boston College Eagles
Pittsburgh Panthers
10/4/25 12PM
BC
PITT
|
–
–
|
+195
-246
|
+6.5 (-110)
-6.5 (-110)
|
O 58.5 (-110)
U 58.5 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Air Force Falcons
Navy Midshipmen
10/4/25 12PM
AF
NAVY
|
–
–
|
+318
-430
|
+12 (-110)
-12 (-110)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Iowa State Cyclones
Cincinnati Bearcats
10/4/25 12PM
IOWAST
CINCY
|
–
–
|
+101
-123
|
+1.5 (-110)
-1.5 (-110)
|
O 54 (-110)
U 54 (-110)
|
|
|
Oct 4, 2025 12:00PM EDT
Army Black Knights
UAB Blazers
10/4/25 12PM
ARMY
UAB
|
–
–
|
-265
+210
|
-7 (-110)
+7 (-110)
|
O 57 (-110)
U 57 (-110)
|
|
|
Oct 4, 2025 1:00PM EDT
Campbell Fighting Camels
NC State Wolfpack
10/4/25 1PM
CAMP
NCST
|
–
–
|
|
+42.5 (-110)
-42.5 (-110)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
|
Oct 4, 2025 1:00PM EDT
Wake Forest Demon Deacons
Virginia Tech Hokies
10/4/25 1PM
WAKE
VATECH
|
–
–
|
+222
-285
|
+7 (-110)
-7 (-110)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Oct 4, 2025 1:00PM EDT
UTSA Roadrunners
Temple Owls
10/4/25 1PM
UTSA
TEMPLE
|
–
–
|
-241
+192
|
-6.5 (-110)
+6.5 (-110)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
|
Oct 4, 2025 2:30PM EDT
Western Michigan Broncos
Umass Minutemen
10/4/25 2:30PM
WMICH
UMASS
|
–
–
|
-553
|
-12.5 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Oct 4, 2025 3:00PM EDT
Oklahoma State Cowboys
Arizona Wildcats
10/4/25 3PM
OKLAST
ARIZ
|
–
–
|
+825
-1699
|
+20.5 (-110)
-20.5 (-110)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Vanderbilt Commodores
Alabama Crimson Tide
10/4/25 3:30PM
VANDY
BAMA
|
–
–
|
+330
-441
|
+10.5 (-110)
-10.5 (-110)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Eastern Michigan Eagles
Buffalo Bulls
10/4/25 3:30PM
EMICH
BUFF
|
–
–
|
+298
-397
|
+10 (-110)
-10 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Washington Huskies
Maryland Terrapins
10/4/25 3:30PM
WASH
MD
|
–
–
|
-255
+200
|
-6.5 (-110)
+6.5 (-110)
|
O 52.5 (-110)
U 52.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Miami Ohio Redhawks
Northern Illinois Huskies
10/4/25 3:30PM
MIAOH
NILL
|
–
–
|
+167
|
+5 (-110)
|
O 38 (-110)
U 38 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Central Michigan Chippewas
Akron Zips
10/4/25 3:30PM
CMICH
AKRON
|
–
–
|
-359
+277
|
-9 (-110)
+9 (-110)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Virginia Cavaliers
Louisville Cardinals
10/4/25 3:30PM
UVA
LVILLE
|
–
–
|
+208
-265
|
+7 (-110)
-7 (-110)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
UL Monroe Warhawks
Northwestern Wildcats
10/4/25 3:30PM
MONROE
NWEST
|
–
–
|
+420
-599
|
+11 (-110)
-11 (-110)
|
O 40.5 (-110)
U 40.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
James Madison Dukes
Georgia State Panthers
10/4/25 3:30PM
JMAD
GAST
|
–
–
|
-1457
+769
|
-19.5 (-110)
+19.5 (-110)
|
O 54 (-110)
U 54 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Syracuse Orange
SMU Mustangs
10/4/25 3:30PM
CUSE
SMU
|
–
–
|
+550
-847
|
+17.5 (-110)
-17.5 (-110)
|
O 58.5 (-110)
U 58.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Boise State Broncos
Notre Dame Fighting Irish
10/4/25 3:30PM
BOISE
ND
|
–
–
|
+796
-1457
|
+20.5 (-110)
-20.5 (-110)
|
O 62.5 (-110)
U 62.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Oregon State Beavers
App State Mountaineers
10/4/25 3:30PM
OREGST
APPST
|
–
–
|
-101
|
+1.5 (-110)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
FIU Panthers
UConn Huskies
10/4/25 3:30PM
FIU
UCONN
|
–
–
|
-310
|
-7.5 (-110)
|
O 55 (-110)
U 55 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Penn State Nittany Lions
UCLA Bruins
10/4/25 3:30PM
PSU
UCLA
|
–
–
|
-4000
+1175
|
-25.5 (-110)
+25.5 (-110)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Oct 4, 2025 3:30PM EDT
Texas Longhorns
Florida Gators
10/4/25 3:30PM
TEXAS
FLA
|
–
–
|
-271
+214
|
-7 (-110)
+7 (-110)
|
O 42.5 (-110)
U 42.5 (-110)
|
|
|
Oct 4, 2025 4:00PM EDT
Kent State Golden Flashes
Oklahoma Sooners
10/4/25 4PM
KENT
OKLA
|
–
–
|
|
+45.5 (-104)
-45.5 (-108)
|
O 53.5 (-110)
U 53.5 (-106)
|
|
|
Oct 4, 2025 4:00PM EDT
Michigan State Spartans
Nebraska Cornhuskers
10/4/25 4PM
MICHST
NEB
|
–
–
|
+370
-526
|
+12 (-110)
-12 (-110)
|
O 49 (-110)
U 49 (-110)
|
|
|
Oct 4, 2025 4:00PM EDT
Texas State Bobcats
Arkansas State Red Wolves
10/4/25 4PM
TEXST
ARKST
|
–
–
|
-481
+350
|
-13.5 (-110)
+13.5 (-110)
|
O 64.5 (-110)
U 64.5 (-110)
|
|
|
Oct 4, 2025 6:00PM EDT
Coastal Carolina Chanticleers
Old Dominion Monarchs
10/4/25 6PM
COAST
OLDDOM
|
–
–
|
+690
-1205
|
+20.5 (-110)
-20.5 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
|
Oct 4, 2025 7:00PM EDT
UNLV Rebels
Wyoming Cowboys
10/4/25 7PM
UNLV
WYO
|
–
–
|
-173
+140
|
-3.5 (-110)
+3.5 (-110)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
|
Oct 4, 2025 7:00PM EDT
Texas Tech Red Raiders
Houston Cougars
10/4/25 7PM
TXTECH
HOU
|
–
–
|
-495
+361
|
-10.5 (-110)
+10.5 (-110)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Oct 4, 2025 7:00PM EDT
South Alabama Jaguars
Troy Trojans
10/4/25 7PM
SBAMA
TROY
|
–
–
|
+114
-139
|
+2.5 (-110)
-2.5 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 4, 2025 7:00PM EDT
Florida Atlantic Owls
Rice Owls
10/4/25 7PM
FAU
RICE
|
–
–
|
+164
-204
|
+4.5 (-110)
-4.5 (-110)
|
O 54 (-110)
U 54 (-110)
|
|
|
Oct 4, 2025 7:30PM EDT
Minnesota Golden Gophers
Ohio State Buckeyes
10/4/25 7:30PM
MINN
OHIOST
|
–
–
|
+1150
-3030
|
+24 (-110)
-24 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 4, 2025 7:30PM EDT
Kansas Jayhawks
UCF Knights
10/4/25 7:30PM
KANSAS
UCF
|
–
–
|
-212
+169
|
-5 (-110)
+5 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
|
Oct 4, 2025 7:30PM EDT
Colorado Buffaloes
TCU Horned Frogs
10/4/25 7:30PM
COLO
TCU
|
–
–
|
+400
-575
|
+13.5 (-110)
-13.5 (-110)
|
O 57.5 (-110)
U 57.5 (-110)
|
|
|
Oct 4, 2025 7:30PM EDT
Mississippi State Bulldogs
Texas A&M Aggies
10/4/25 7:30PM
MISSST
TEXAM
|
–
–
|
+440
-649
|
+14 (-110)
-14 (-110)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
|
Oct 4, 2025 7:30PM EDT
Miami Hurricanes
Florida State Seminoles
10/4/25 7:30PM
MIAMI
FSU
|
–
–
|
-202
+162
|
-4.5 (-110)
+4.5 (-110)
|
O 54 (-110)
U 54 (-110)
|
|
|
Oct 4, 2025 8:00PM EDT
Tulsa Golden Hurricane
Memphis Tigers
10/4/25 8PM
TULSA
MEMP
|
–
–
|
+880
-1699
|
+20.5 (-110)
-20.5 (-110)
|
O 57 (-110)
U 57 (-110)
|
|
|
Oct 4, 2025 9:30PM EDT
Duke Blue Devils
California Golden Bears
10/4/25 9:30PM
DUKE
CAL
|
–
–
|
-155
+130
|
-3 (-110)
+3 (-110)
|
O 57.5 (-110)
U 57.5 (-110)
|
|
|
Oct 4, 2025 10:30PM EDT
Nevada Wolf Pack
Fresno State Bulldogs
10/4/25 10:30PM
NEVADA
FRESNO
|
–
–
|
+436
-657
|
+14 (-110)
-14 (-110)
|
O 45 (-110)
U 45 (-110)
|
|
|
Oct 11, 2025 3:30PM EDT
Indiana Hoosiers
Oregon Ducks
10/11/25 3:30PM
IND
OREG
|
–
–
|
+315
-410
|
+10.5 (-106)
-10.5 (-114)
|
O 51.5 (-115)
U 51.5 (-105)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Penn State Nittany Lions vs. Ohio State Buckeyes on November 01, 2025 at .
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
| CFB |
   LEAN |    %WIN |    UNITS | RESULT |
|---|---|---|---|---|
| EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
| SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
| BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
| TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
| UK@SC | SC -5.5 | 54.8% | 4 | WIN |
| WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
| JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
| NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
| ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
| TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
| ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
| WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
| TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |
| UNC@UCF | UCF -6.5 | 54.4% | 4 | WIN |
| ARKST@KENSAW | KENSAW +4.5 | 54.5% | 4 | WIN |
| ILL@IND | IND -6 | 53.2% | 3 | WIN |
| SELOU@LSU | LSU -47.5 | 55.3% | 5 | LOSS |
| TNMART@MIZZST | MIZZST -14.5 | 56.2% | 6 | WIN |
| FRESNO@HAWAII | HAWAII +3 | 56.6% | 6 | WIN |
| MRSHL@MTSU | MTSU +2.5 | 56.8% | 6 | LOSS |
| MICH@NEB | NEB +1.5 | 57.3% | 7 | LOSS |
| WASH@WASHST | DENZEL BOSTON UNDER 69.5 RECV YDS | 56.2% | 6 | LOSS |
| IOWA@RUT | ANTWAN RAYMOND OVER 0.5 TOUCHDOWNS | 54.4% | 4 | WIN |
| GEORGIA@TENN | UNDER 50.5 | 55.5% | 6 | LOSS |
| ARK@OLEMISS | MISS -225 | 72.0% | 9 | WIN |
| DUKE@TULANE | TULANE -120 | 56.5% | 4 | WIN |
| ARK@OLEMISS | MISS -6.5 | 53.9% | 3 | LOSS |
| AKRON@UAB | UAB -11 | 54.7% | 4 | LOSS |
| UCONN@DEL | DEL +9.5 | 55.0% | 5 | WIN |
| APLST@USM | USM +4 | 55.3% | 6 | WIN |
| MERIMK@KENSAW | KENSAW -13.5 | 56.2% | 7 | WIN |
| UMASS@IOWA | IOWA -34.5 | 56.4% | 7 | WIN |
| UMASS@IOWA | JAZIUN PATTERSON UNDER 0.5 RUSH TDS | 54.8% | 4 | WIN |
| NMEX@UCLA | NICO IAMALEAVA UNDER 31.5 PASS ATT | 53.4% | 3 | LOSS |
| KSTATE@ARIZ | ARIZ +1.5 | 56.1% | 6 | WIN |
| BC@MICHST | NICK MARSH OVER 47.5 RCV YDS | 53.6% | 3 | WIN |
| ARIZST@MISSST | MISSST +7 | 54.2% | 4 | WIN |
| TULSA@NMEXST | NMEXST +3.5 | 56.9% | 6 | WIN |
| UCLA@UNLV | OVER 54.5 | 56.2% | 6 | LOSS |
| FRESNO@OREGST | FRESNO +1.5 | 54.7% | 4 | WIN |
| VANDY@VATECH | VANDY +2.5 | 55.8% | 5 | WIN |
| JMAD@LVILLE | LVILLE -14.5 | 54.0% | 3 | LOSS |
| TCU@UNC | JOSEPH MANJACK OVER 37.5 RECV YDS | 53.8% | 3 | LOSS |
| ND@MIAMI | MIAMI +3 | 55.2% | 6 | WIN |
| MISSST@USM | USM +14.5 | 56.0% | 6 | LOSS |
| UTAH@UCLA | UCLA +5.5 | 56.2% | 6 | LOSS |
| CAL@OREGST | OREGST +1.5 | 55.1% | 5 | LOSS |
| FAU@MD | MD -13.5 | 55.2% | 5 | WIN |
| GAS@FRESNO | FRESNO +2 | 55.2% | 5 | WIN |
| TOLEDO@UK | UK -9.5 | 56.2% | 6 | LOSS |
| AUSTPEAY@MTSU | PEAY +12.5 | 56.2% | 6 | WIN |