Colorado State vs Wyoming Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 25)

Updated: 2025-10-18T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Colorado State Rams travel to take on the Wyoming Cowboys in the Border War rivalry on October 25, 2025, in what looms as a pivotal Mountain West clash for both programs. Colorado State enters already reeling from a coaching change and looking to right the ship, while Wyoming seeks stability at home as they attempt to build momentum in their conference campaign.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 25, 2025

Start Time: 7:30 PM EST​

Venue: War Memorial Stadium​

Cowboys Record: (3-4)

Rams Record: (2-5)

OPENING ODDS

COLOST Moneyline: +178

WYO Moneyline: -216

COLOST Spread: +5.5

WYO Spread: -5.5

Over/Under: 46.5

COLOST
Betting Trends

  • Colorado State has faced significant struggles this season, with few clear trends available, but bookmakers noted they had covered three times in their first six games this year.

WYO
Betting Trends

  • Wyoming enters the game with a .500 record against the spread (3-3) as of their most recent publicly listed betting record.

MATCHUP TRENDS

  • From a betting viewpoint, this game offers compelling angles: Colorado State’s turmoil—highlighted by a coaching change and inconsistent performance—may mean they are undervalued as road underdogs, while Wyoming’s home field and slight statistical edge could be overestimated if they fail to execute. The Border War rivalry adds an emotional component that sometimes skews spread movement. Key metrics to watch: Colorado State’s offense averaging about 22.3 points per game versus Wyoming’s defense allowing about 22.3 points per game; Wyoming’s offense averaging 5.38 yards per play and converting only 35.4 % of third-downs versus Colorado State’s conversion rate hovering near 35 % as well. If Wisconsin—or sorry, Wyoming—can force shorter fields and win the turnover battle, the home side has value; conversely, if Colorado State’s new leadership steals an early edge, the road cover is intriguing.

COLOST vs. WYO
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Dupree under 44.5 Rushing Yards.

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Colorado State vs Wyoming Prediction & Odds:
Free CFB Betting Insights for 10/25/25

The October 25, 2025 edition of the Border War between the Colorado State Rams and the Wyoming Cowboys at War Memorial Stadium in Laramie promises to deliver another gritty and emotional chapter in one of the Mountain West’s oldest rivalries. These two programs, separated by just over 60 miles of interstate, always bring added intensity to their meetings, and this year’s matchup is no exception. Colorado State enters the game searching for stability after a turbulent season that saw head coach Jay Norvell dismissed earlier in the month, while Wyoming looks to capitalize on its home-field advantage and maintain momentum in the Mountain West standings. The Rams come in with a 2-4 record, struggling to find consistency on both sides of the ball. They average 22.3 points per game on offense while allowing 26.3 points per game defensively, numbers that illustrate their inability to finish drives and their tendency to give up big plays at critical moments. Their offense, led by quarterback Brayden Fowler-Nicolosi, has shown flashes of efficiency, particularly in the short passing game, but turnovers and third-down inefficiency (converting just 35% of attempts) have plagued them. The running game, powered by Vann Schield and Kobe Johnson, averages a modest 4.3 yards per carry and has been serviceable but not explosive. Wide receiver Tory Horton remains the focal point of the offense, leading the team in receptions and yards, but opposing defenses have increasingly focused on limiting his deep-ball opportunities, forcing Colorado State to rely on underneath routes and short-yardage gains. Defensively, the Rams have had some bright spots—linebacker Jack Howell leads the unit in tackles, and the front seven has improved against the run—but inconsistency in the secondary continues to cost them in key moments. The defense gives up 5.3 yards per play and has struggled to generate turnovers, a trend that must change if they want to pull off the upset in Laramie. On the other sideline, Wyoming enters the rivalry matchup with a 3-3 record and the confidence that comes from playing at War Memorial Stadium, one of the most challenging venues in college football due to its high altitude and unpredictable winds. The Cowboys’ identity under head coach Jay Sawvel remains rooted in physicality and discipline.

Their offense has been steady, if unspectacular, averaging 19.8 points per game and 5.4 yards per play. Quarterback Andrew Peasley brings veteran poise to the position, completing over 60% of his passes for roughly 1,200 yards and seven touchdowns while minimizing turnovers. Wyoming’s strength, however, lies in its ground game and offensive line, led by running back Harrison Waylee, who averages nearly five yards per carry and serves as the team’s offensive catalyst. The Cowboys’ ability to run between the tackles and control time of possession has kept them competitive in every game. Defensively, Wyoming is as tough as ever, allowing just 22.3 points per game and limiting opponents to 5.0 yards per play. Linebackers Easton Gibbs and Shae Suiaunoa anchor a fast, physical defense that prides itself on sound tackling and gap control. The Cowboys excel in forcing opponents into third-and-long situations, a strength that could spell trouble for a Colorado State offense already struggling to sustain drives. Special teams are another advantage for Wyoming, with kicker John Hoyland continuing to be one of the most reliable in the conference. Strategically, this game will hinge on tempo, turnovers, and physical control. Colorado State will try to spread Wyoming’s defense horizontally and create space for Horton and its running backs, while Wyoming will look to impose its will through the trenches and control clock with methodical drives. From a betting perspective, Wyoming’s 3-3 ATS record and home dominance make them a slight favorite, but rivalry games tend to defy trends. Expect a low-scoring, defensive battle defined by field position, where Wyoming’s physicality and altitude advantage give them the edge late. If Colorado State can limit mistakes and find early offensive rhythm, they can make it close—but Wyoming’s stability and toughness should ultimately carry them to another hard-earned Border War victory.

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Colorado State Rams CFB Preview

The Colorado State Rams head into the October 25, 2025 Border War matchup against Wyoming looking to rediscover stability and pride after a turbulent first half of the season defined by inconsistency and a recent coaching change. The Rams enter at 2-4 overall and 1-2 in Mountain West play, and the dismissal of head coach Jay Norvell earlier in October has forced the program to quickly regroup under interim leadership. Despite the turmoil, Colorado State still has enough talent on both sides of the ball to make this rivalry game competitive if they can limit turnovers and execute cleanly. Offensively, the Rams average 22.3 points per game and 5.3 yards per play, numbers that suggest potential but highlight their inability to finish drives. Quarterback Brayden Fowler-Nicolosi has been both dynamic and erratic, throwing for over 1,600 yards and 10 touchdowns but also committing costly interceptions at critical junctures. When in rhythm, Fowler-Nicolosi shows impressive arm strength and command of the offense, but inconsistency in protection and timing routes has limited Colorado State’s efficiency. His connection with star wide receiver Tory Horton remains the team’s most dangerous weapon—Horton leads the Rams with over 600 yards and five touchdowns, consistently drawing double coverage and attention from opposing defenses. Alongside him, Louis Brown and tight end Dallin Holker have emerged as reliable secondary options in the passing game. The running attack, however, has been the Achilles’ heel of this offense, averaging just 4.3 yards per carry behind an offensive line that has struggled to open consistent lanes for backs Vann Schield and Kobe Johnson. Establishing the ground game early will be critical to taking pressure off Fowler-Nicolosi and allowing the Rams to control tempo against Wyoming’s disciplined front seven.

Defensively, Colorado State has shown flashes of improvement, especially against the run, but lapses in the secondary have hurt them in big moments. The unit allows 26.3 points per game and nearly 5.3 yards per play, numbers inflated by miscommunications and missed tackles. Linebacker Jack Howell has been the heart of the defense, leading the team in tackles and bringing an aggressive, downhill style that fits perfectly in a rivalry setting. Edge rusher Mohamed Kamara has been the team’s top disruptor, recording five sacks and routinely forcing hurried throws from opposing quarterbacks. The Rams’ defensive game plan against Wyoming will likely center on stopping running back Harrison Waylee, who powers the Cowboys’ rushing attack and thrives in a ball-control offense. For Colorado State to have success, they must win early downs, force Wyoming into passing situations, and capitalize on turnover opportunities. Special teams have been a mixed bag—kicker Jordan Noyes has been reliable inside 40 yards, while punter Ryan McCarthy has been key in flipping field position in tight games. From a betting perspective, the Rams’ 3-3 ATS mark suggests they’ve been more competitive than their record implies, and as road underdogs in a rivalry game, they carry upset potential if their offense finds rhythm early. The emotional nature of the Border War often levels the playing field, and if Colorado State plays with discipline and minimizes penalties, they could stay within striking distance deep into the fourth quarter. The path to victory will depend on controlling the ball, forcing takeaways, and capitalizing on red-zone chances. While Wyoming’s altitude and home-field advantage present challenges, this rivalry tends to bring out the Rams’ best effort, and if their offensive leaders step up under the interim regime, an upset in Laramie isn’t out of the question.

The Colorado State Rams travel to take on the Wyoming Cowboys in the Border War rivalry on October 25, 2025, in what looms as a pivotal Mountain West clash for both programs. Colorado State enters already reeling from a coaching change and looking to right the ship, while Wyoming seeks stability at home as they attempt to build momentum in their conference campaign. Colorado State vs Wyoming AI Prediction: Free CFB Betting Insights for Oct 25. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Wyoming Cowboys CFB Preview

The Wyoming Cowboys return to War Memorial Stadium on October 25, 2025, to host archrival Colorado State in one of the most anticipated rivalry games in the Mountain West—the Border War. Under head coach Jay Sawvel, the Cowboys enter this clash with a 3-3 record, looking to reestablish consistency and defend their home turf in front of a raucous Laramie crowd. Known for their toughness and physicality, the Cowboys are built around an old-school identity that emphasizes controlling the line of scrimmage, dominating time of possession, and punishing opponents with a balanced attack. Wyoming’s offense has been steady, if not explosive, averaging 19.8 points per game and 5.4 yards per play. Quarterback Andrew Peasley remains the veteran presence at the helm, bringing leadership and poise to the offense. He has thrown for roughly 1,200 yards and seven touchdowns on the season while keeping turnovers low, allowing the Cowboys to stay competitive in most games. Peasley’s command of the system and ability to extend plays with his legs add an extra dimension to Wyoming’s otherwise traditional offensive scheme. The ground game remains the heartbeat of the team, powered by running back Harrison Waylee, who averages nearly five yards per carry and serves as the primary catalyst for the Cowboys’ offensive rhythm. Waylee’s vision, patience, and ability to pick up yards after contact make him a consistent threat to move the chains. He’s supported by a cohesive offensive line led by tackle Frank Crum, a future NFL prospect, whose physical play and experience set the tone for a unit that thrives in power-run situations. The Cowboys’ receiving corps, though not flashy, is efficient, with wideouts Wyatt Wieland and Ayir Asante combining for over 600 yards and several clutch third-down conversions. Wyoming’s defense remains its backbone and identity, allowing just 22.3 points per game while holding opponents to 5.0 yards per play.

The front seven, anchored by linebacker Easton Gibbs and defensive lineman DeVonne Harris, has been outstanding against the run and relentless in creating pressure on opposing quarterbacks. Gibbs, in particular, has been a tackling machine, providing leadership and consistency in the middle of the defense. The secondary, led by cornerback Kolbey Taylor and safety Wyett Ekeler, has shown improvement, forcing timely turnovers and limiting explosive plays. Defensively, Wyoming’s biggest strength lies in its gap discipline and ability to force opponents into long third-down situations—a key advantage against a Colorado State offense that struggles to sustain drives. The Cowboys’ special teams also play a crucial role, with kicker John Hoyland continuing to be one of the most dependable in the Mountain West, boasting accuracy from beyond 50 yards, while punter Clayton Stewart consistently flips field position. Strategically, Wyoming will aim to control the tempo from the opening snap—establishing the run early, wearing down Colorado State’s front, and using play-action passes to exploit mismatches. Defensively, the Cowboys’ game plan will focus on pressuring Rams quarterback Brayden Fowler-Nicolosi and containing wide receiver Tory Horton, who has been Colorado State’s most explosive weapon. If Wyoming can force turnovers and control possession, they’ll be in prime position to capture another Border War victory. From a betting standpoint, Wyoming’s even 3-3 ATS record reflects their reliability when playing disciplined, mistake-free football, particularly at home, where they’ve historically performed well. The altitude and cold October conditions in Laramie are additional weapons for the Cowboys, often wearing down visiting teams unaccustomed to the environment. Expect a physical, grind-it-out contest where Wyoming’s toughness and defensive execution shine through. If the offense sustains drives and avoids turnovers, the Cowboys have every opportunity to outlast Colorado State in a close, hard-fought rivalry game that once again underscores the grit and pride of Wyoming football.

Colorado State vs Wyoming Prop Picks (AI)

AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the Rams and Cowboys play there’s always several intriguing angles to key in on. Not to mention games played at War Memorial Stadium in Oct can often follow normal, predictable patterns.

Remi's searched hard and found the best prop for this matchup: J. Dupree under 44.5 Rushing Yards.

Colorado State vs Wyoming Prediction (AI)

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Remi, our AI sports genius, has been pouring over mountains of data from every past game between the Rams and Cowboys and using recursive machine learning and industry leading AI to crunch the data to a single cover probability.

The Algorithm has been most focused on the linear correlation of factor emotional bettors regularly put on player performance factors between a Rams team going up against a possibly improved Cowboys team. It appears the true game analytics might reflect a strong lean against one Vegas line specifically.

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Below is our current AI Colorado State vs Wyoming picks, computer picks Rams vs Cowboys, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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Colorado State Betting Trends

Colorado State has faced significant struggles this season, with few clear trends available, but bookmakers noted they had covered three times in their first six games this year.

Wyoming Betting Trends

Wyoming enters the game with a .500 record against the spread (3-3) as of their most recent publicly listed betting record.

Rams vs. Cowboys Matchup Trends

From a betting viewpoint, this game offers compelling angles: Colorado State’s turmoil—highlighted by a coaching change and inconsistent performance—may mean they are undervalued as road underdogs, while Wyoming’s home field and slight statistical edge could be overestimated if they fail to execute. The Border War rivalry adds an emotional component that sometimes skews spread movement. Key metrics to watch: Colorado State’s offense averaging about 22.3 points per game versus Wyoming’s defense allowing about 22.3 points per game; Wyoming’s offense averaging 5.38 yards per play and converting only 35.4 % of third-downs versus Colorado State’s conversion rate hovering near 35 % as well. If Wisconsin—or sorry, Wyoming—can force shorter fields and win the turnover battle, the home side has value; conversely, if Colorado State’s new leadership steals an early edge, the road cover is intriguing.

Colorado State vs. Wyoming Game Info

October 25, 2025 • 7:30 PM EST • War Memorial Stadium

Colorado State vs. Wyoming Odds

Remi is pouring through mountains of data points on each player. In fact, anytime the Colorado State vs Wyoming trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude almost always follow normal, predictable patterns.

Colorado State vs Wyoming

Colorado State vs Wyoming Live Odds

Games PTS ML SPR O/U
Dec 5, 2025 7:00PM EST
Troy Trojans
James Madison Dukes
12/5/25 7PM
TROY
JMAD
+1300
-2500
+23.5 (-108)
-23.5 (-112)
O 46.5 (-110)
U 46.5 (-110)
Dec 5, 2025 7:00PM EST
Kennesaw State Owls
Jacksonville State Gamecocks
12/5/25 7PM
KENSAW
JAXST
-136
+116
-2.5 (-110)
+2.5 (-110)
O 60.5 (-110)
U 60.5 (-110)
Dec 5, 2025 8:00PM EST
North Texas Mean Green
Tulane Green Wave
12/5/25 8PM
NOTEX
TULANE
-130
+110
-2.5 (-112)
+2.5 (-108)
O 66.5 (-115)
U 66.5 (-105)
Dec 5, 2025 8:01PM EST
UNLV Rebels
Boise State Broncos
12/5/25 8:01PM
UNLV
BOISE
+184
-220
+5.5 (-110)
-5.5 (-110)
O 58.5 (-115)
U 58.5 (-105)
Dec 6, 2025 12:00PM EST
Miami Ohio Redhawks
Western Michigan Broncos
12/6/25 12PM
MIAOH
WMICH
 
-132
 
-1.5 (-115)
O 42.5 (-115)
U 42.5 (-105)
Dec 6, 2025 12:00PM EST
BYU Cougars
Texas Tech Red Raiders
12/6/25 12PM
BYU
TXTECH
+430
-560
+12.5 (-105)
-12.5 (-115)
O 49.5 (-108)
U 49.5 (-112)
Dec 6, 2025 4:00PM EST
Georgia Bulldogs
Alabama Crimson Tide
12/6/25 4PM
UGA
BAMA
-134
+114
-2.5 (-115)
+2.5 (-105)
O 48.5 (-106)
U 48.5 (-114)
Dec 6, 2025 8:00PM EST
Duke Blue Devils
Virginia Cavaliers
12/6/25 8PM
DUKE
UVA
+156
-186
+3.5 (-102)
-3.5 (-120)
O 57.5 (-115)
U 57.5 (-105)
Dec 6, 2025 8:01PM EST
Indiana Hoosiers
Ohio State Buckeyes
12/6/25 8:01PM
IND
OHIOST
+158
-188
+4.5 (-115)
-4.5 (-105)
O 47.5 (-114)
U 47.5 (-106)
Dec 13, 2025 3:00PM EST
Army Black Knights
Navy Midshipmen
12/13/25 3PM
ARMY
NAVY
+172
-210
+4.5 (-105)
-4.5 (-115)
O 38.5 (-110)
U 38.5 (-110)

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We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Colorado State Rams vs. Wyoming Cowboys on October 25, 2025 at War Memorial Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

LEAN %WIN UNITS RESULT
COLO@KSTATE COLO +17.5 54.0% 4 WIN
PSU@RUT RUT +14 52.8% 1 WIN
OHIOST@MICH MICH +10.5 56.4% 6 LOSS
VATECH@UVA VATECH +8 57.8% 7 LOSS
NWEST@ILL LUKE ALTMYER UNDER 19.5 PASS COMP 54.3% 4 WIN
ORE@WAS DEMOND WILLIAMS JR UNDER 43.5 RUSH YDS 55.2% 5 WIN
MIAMI@VATECH VATECH +18.5 54.2% 4 WIN
GAST@TROY TROY -9.5 55.7% 5 WIN
DEL@WAKE DEL +18 56.7% 6 LOSS
NMEX@AF NMEX -3.5 56.1% 5 WIN
WASHST@JMAD WASHST +14.5 55.3% 5 WIN
ILL@WISC WISC +9 55.1% 5 WIN
WKY@LSU WKY +23.5 56.3% 6 WIN
WASH@UCLA DEMOND WILLIAMS UNDER 27.5 PASS ATT 56.3% 6 WIN
TCU@HOU AMARE THOMAS OVER 69.5 RECV YDS 55.2% 5 WIN
TEX@UGA NATE FRAZIER UNDER 65.5 RUSH + REC YDS 55.5% 5 WIN
PUR@WASH ANTONIO HARRIS UNDER 73.5 RUSH + REC YDS 54.1% 4 WIN
OKLA@BAMA UNDER 46 52.4% 2 WIN
UVA@DUKE DUKE -3.5 54.7% 3 LOSS
OKLA@BAMA BAMA -6 54.5% 3 LOSS
OREGST@TULSA OREGST -120 55.6% 5 LOSS
UTEP@MIZZST MIZZST -5 54.3% 4 WIN
COLOST@NMEX NMEX -14 57.1% 6 LOSS
PSU@MICHST MICHST +7.5 56.5% 6 LOSS
MISSST@MIZZOU MISSST +7.5 57.2% 7 LOSS
FAU@TULANE FAU +17.5 56.0% 6 WIN
NCST@MIAMI NCST +15.5 57.1% 7 LOSS
KENTST@AKRON AKRON -6.5 55.4% 5 LOSS
JAXST@UTEP JAXST -105 57.0% 7 WIN
FSU@CLEM CLEM -118 57.1% 5 WIN
UNLV@COLOST UNLV -4 55.2% 5 WIN
OREG@IOWA IOWA +6.5 53.3% 2 WIN
NEB@UCLA NEB +1.5 55.8% 5 WIN
KENSAW@NMEXST NMEXST +10 56.5% 6 WIN
STNFRD@UNC STNFRD +7.5 53.8% 3 WIN
DUKE@UCONN UCONN +8.5 57.9% 7 WIN
NEVADA@UTAHST NEVADA +9.5 55.9% 5 LOSS
SAMST@OREGST SAMST +21 57.7% 7 WIN
NEB@UCLA NICO IAMALEAVA UNDER 180.5 PASS YDS 56.6% 6 LOSS
HOU@UCF HOU -112 58.0% 6 WIN
GASTHRN@APPST GASTHRN +180 36.5% 2 WIN
KENTST@BALLST BALLST -2.5 54.5% 4 WIN
WAKE@FSU WAKE +10.5 56.4% 6 LOSS
WYO@SDGST SDGST -10.5 56.7% 7 WIN
OKLA@TENN TENN -130 58.3% 5 LOSS
GATECH@NCST GATECH -5 56.4% 6 LOSS
MIAMI@SMU MIAMI -10 54.3% 4 LOSS
IND@MD MD +21.5 54.6% 4 LOSS
CINCY@UTAH CINCY +11 57.6% 7 LOSS
OLDDOM@LAMON LAMON +17 58.4% 8 LOSS
VANDY@TEXAS OVER 46.5 53.7% 2 WIN