Boston College vs Louisville Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 25)

Updated: 2025-10-18T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Boston College Eagles visit the Louisville Cardinals on October 25, 2025 with the Cardinals riding momentum as one of the ACC’s surprise teams and the Eagles still seeking consistency in what has been a tough campaign. Louisville boasts a strong record and upward trajectory, while Boston College is trying to rediscover its identity and avoid falling further behind in conference competition.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 25, 2025

Start Time: 7:30 PM EST​

Venue: L&N Federal Credit Union Stadium​

Cardinals Record: (5-1)

Eagles Record: (1-6)

OPENING ODDS

BC Moneyline: +1280

LVILLE Moneyline: -3448

BC Spread: +23.5

LVILLE Spread: -23.5

Over/Under: 53.5

BC
Betting Trends

  • Boston College has covered the spread in only 2 of their 6 games so far this season, translating to roughly a 33.3% ATS cover rate.

LVILLE
Betting Trends

  • Louisville has covered the spread in 5 of their 6 games, putting them at approximately an 83.3% ATS cover rate this season.

MATCHUP TRENDS

  • This matchup presents a clear betting-angle contrast: Louisville is outperforming expectations and covering at a high rate (83.3%), while Boston College is underperforming and struggling to cover. That dynamic suggests value may lean toward the home side, especially given Louisville’s momentum and Boston College’s difficulties. Additional intrigue comes from the offensive and defensive trends: Louisville’s upward offensive rhythm and Boston College’s defense allowing over 33 points per game create a template where Louisville could both win and cover. Conversely, Boston College will need to tighten up defensively and find offensive bursts to overcome both the opponent and the betting line.

BC vs. LVILLE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup:

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Boston College vs Louisville Prediction & Odds:
Free CFB Betting Insights for 10/25/25

The October 25, 2025 matchup between the Boston College Eagles and the Louisville Cardinals presents a classic ACC contrast between a team trying to stay afloat and one asserting itself as a legitimate conference contender. Louisville has emerged as one of the ACC’s most complete programs this season, sitting at 5-1 overall with a strong 5-1 record against the spread, and head coach Jeff Brohm has his squad firing on all cylinders. The Cardinals have blended explosive offensive execution with defensive discipline, averaging just over 34 points per game while holding opponents to fewer than 18. Their offensive rhythm, powered by efficient quarterback play and a balanced attack, has made them difficult to defend; they can pound defenses on the ground with speed and power while also striking vertically through the air. Quarterback Jack Plummer’s command of Brohm’s system has been evident, spreading the ball effectively to a deep receiver corps and using tempo to keep defenses on their heels. Louisville’s running game, anchored by a consistent offensive line and capable backs, has been key to controlling game flow and setting up play-action opportunities. Defensively, the Cardinals have been equally impressive, giving up only 5.1 yards per play and excelling in red-zone situations. Their ability to pressure quarterbacks while maintaining sound coverage has allowed them to neutralize explosive offenses, and they’ll look to continue that trend against a Boston College team that has struggled to sustain drives.

The Eagles, entering at 1-5 with a 2-4 record against the spread, have shown flashes of offensive potential but have been unable to pair that with consistency or defensive reliability. They’re averaging around 28 points per game but allowing over 33, and their run defense, in particular, has been a weak point, surrendering more than 180 yards per contest. Quarterback Thomas Castellanos remains a bright spot, giving the Eagles mobility and creativity, but his dual-threat style has been offset by turnovers and inconsistent accuracy when forced into passing downs. For Boston College to have a chance in this game, it must find balance early—establishing the run, managing clock, and avoiding the quick three-and-outs that have plagued them in recent weeks. Defensively, they’ll need to find a way to contain Louisville’s balanced attack and prevent early big plays that could turn this into another blowout. The crowd at L&N Federal Credit Union Stadium will also be a factor, as Louisville has played with noticeable energy and confidence at home, often feeding off its environment to overwhelm opponents early. From a betting perspective, the numbers heavily favor Louisville; the Cardinals’ 83% cover rate contrasts sharply with Boston College’s struggles both straight up and against the line. Statistically and situationally, Louisville holds every major edge—home-field advantage, offensive production, defensive stability, and momentum. Unless the Eagles can generate turnovers and drastically outperform recent trends, this matchup is likely to follow the pattern of Louisville asserting control early and managing the game with efficiency. Expect the Cardinals’ balanced attack to set the tone, their defense to limit Boston College’s mobility, and their overall execution to lead them comfortably toward another conference victory that strengthens their ACC standing and postseason outlook.

Boston College Eagles CFB Preview

The Boston College Eagles head into their October 25, 2025 road matchup against the Louisville Cardinals desperate to find stability in a season that has been defined by inconsistency and missed opportunities. Sitting at 1-5 overall and struggling to find rhythm on both sides of the ball, the Eagles are fighting to avoid falling deeper into the ACC basement. Under head coach Jeff Hafley, Boston College has shown flashes of competitiveness but too often collapses in key moments, particularly against more balanced and physical teams. Offensively, quarterback Thomas Castellanos remains the centerpiece of the attack and one of the few bright spots, using his dual-threat ability to keep defenses honest. Castellanos has accounted for the majority of the team’s production both through the air and on the ground, but his effectiveness has been limited by poor protection and a lack of consistency among the offensive skill positions. The Eagles are averaging around 27 points per game but have struggled to sustain drives, converting just over 35 percent of their third downs, while their offensive line has allowed too many pressures to establish rhythm. Their rushing attack has been underwhelming at just over three yards per carry, which puts too much pressure on Castellanos to create magic on broken plays. Against a Louisville defense that thrives on discipline and aggression, Boston College will need to be patient, control the ball, and avoid early turnovers that could bury them before halftime. Defensively, the Eagles have struggled mightily, allowing over 33 points per contest and frequently breaking down in coverage against teams with speed and vertical threats. Louisville’s balanced offense, led by quarterback Jack Plummer and a strong running game, poses a serious challenge for a unit that has yet to string together four quarters of consistent football.

The Eagles’ front seven must find a way to generate pressure without compromising coverage lanes, while their linebackers must contain the edges to prevent Louisville’s running backs from dictating tempo. Boston College has shown some ability to force turnovers, and they’ll need multiple takeaways to have any chance of staying competitive in this one. On the road, composure will be critical, as Louisville’s home-field environment has fueled fast starts all season. The Eagles must establish tempo early, perhaps using quick passes and designed quarterback runs to move the chains and keep the defense off the field. From a betting perspective, Boston College has covered the spread in only two of its first six games, indicating consistent underperformance relative to expectations. The margin for error is razor-thin: they must play their cleanest game of the season, avoid self-inflicted wounds, and capitalize on every scoring opportunity to make this a four-quarter contest. Special teams could offer a rare advantage if the Eagles can flip field position or steal momentum with a big return or turnover. Ultimately, Boston College’s path to an upset depends on limiting Louisville’s explosive plays and finding balance offensively. If Castellanos can stay upright, use his legs effectively, and get support from his offensive line, the Eagles can hang around longer than expected. However, if the same issues that have plagued them all season—poor tackling, penalties, and defensive lapses—resurface, Louisville’s superior depth and discipline will likely overwhelm them by the second half, continuing what has been a difficult campaign for the Eagles on both the field and the betting board.

The Boston College Eagles visit the Louisville Cardinals on October 25, 2025 with the Cardinals riding momentum as one of the ACC’s surprise teams and the Eagles still seeking consistency in what has been a tough campaign. Louisville boasts a strong record and upward trajectory, while Boston College is trying to rediscover its identity and avoid falling further behind in conference competition. Boston College vs Louisville AI Prediction: Free CFB Betting Insights for Oct 25. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Louisville Cardinals CFB Preview

The Louisville Cardinals return home on October 25, 2025, to face the struggling Boston College Eagles, and they do so with confidence, rhythm, and control of their ACC destiny firmly within reach. Under head coach Jeff Brohm, Louisville has evolved into one of the conference’s most balanced and dangerous teams, boasting a 5-1 record overall and a stellar 5-1 mark against the spread that highlights both dominance and consistency. The Cardinals have thrived behind a versatile offense and a defense that has been far more disciplined than in years past, allowing them to control games from start to finish. Offensively, quarterback Jack Plummer has found his groove in Brohm’s system, combining precision passing with smart decision-making to produce one of the most efficient passing attacks in the ACC. He’s complemented by a deep stable of playmakers, including Jamari Thrash, who stretches defenses vertically, and a committee of backs led by Isaac Guerendo and Jawhar Jordan, who bring power and explosiveness to the ground game. The Cardinals are averaging over 34 points per game while piling up more than 400 yards of total offense, and their offensive line—long considered a question mark—has been a stabilizing force, creating clean pockets and opening running lanes against even the most physical fronts. At home in L&N Federal Credit Union Stadium, Louisville’s offense has been particularly sharp, averaging nearly 38 points and playing with tempo and confidence from the first snap. On defense, the Cardinals have been every bit as impressive, giving up fewer than 18 points per game and excelling in red-zone stands.

Their front seven has developed a reputation for toughness, combining gap discipline with speed on the edges, while the secondary has grown into a strength, holding opponents to under 200 passing yards per game. Against a Boston College offense that relies heavily on quarterback Thomas Castellanos’ improvisation and scrambling ability, Louisville’s defense will aim to collapse the pocket, force the Eagles into predictable passing situations, and capitalize on turnovers—a category where the Cardinals have thrived all season. Their linebackers, led by standout TJ Quinn, will play a crucial role in containing Castellanos’ mobility while maintaining coverage integrity against short and intermediate routes. Special teams have also been a steady advantage, with kicker Brock Travelstead providing reliability and the return game consistently creating favorable field position. From a betting standpoint, Louisville’s 83% cover rate speaks to a team that not only wins but often exceeds expectations, especially at home, where they’ve been dominant on both sides of the ball. The formula for success in this matchup is clear: start fast, force Boston College to chase, and let their depth and precision take over as the game wears on. If Louisville executes as they have throughout the season—maintaining ball security, playing disciplined defense, and staying aggressive offensively—they should have little trouble controlling this game. For Boston College to have a chance, Louisville would need to beat itself with turnovers or lapses in focus, neither of which has been a hallmark under Brohm. Expect the Cardinals to play with confidence and urgency, using this matchup not only to strengthen their position in the ACC standings but also to continue building the consistency and dominance that have defined their rise under Brohm’s leadership. With superior balance, execution, and home-field advantage, Louisville enters as a heavy favorite to win convincingly and once again cover the spread in front of a fan base that’s starting to believe this could be a special season.

Boston College vs. Louisville Prop Picks (AI)

Remi is pouring through loads of data on each team. In fact, anytime the Eagles and Cardinals play there’s always several intriguing trends to key in on. Not to mention games played at L&N Federal Credit Union Stadium in Oct seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup:

Boston College vs. Louisville Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over mountains of data from every simulation between the Eagles and Cardinals and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most watching on the linear correlation of emphasis human bettors often put on Louisville’s strength factors between a Eagles team going up against a possibly improved Cardinals team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Boston College vs Louisville picks, computer picks Eagles vs Cardinals, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Eagles Betting Trends

Boston College has covered the spread in only 2 of their 6 games so far this season, translating to roughly a 33.3% ATS cover rate.

Cardinals Betting Trends

Louisville has covered the spread in 5 of their 6 games, putting them at approximately an 83.3% ATS cover rate this season.

Eagles vs. Cardinals Matchup Trends

This matchup presents a clear betting-angle contrast: Louisville is outperforming expectations and covering at a high rate (83.3%), while Boston College is underperforming and struggling to cover. That dynamic suggests value may lean toward the home side, especially given Louisville’s momentum and Boston College’s difficulties. Additional intrigue comes from the offensive and defensive trends: Louisville’s upward offensive rhythm and Boston College’s defense allowing over 33 points per game create a template where Louisville could both win and cover. Conversely, Boston College will need to tighten up defensively and find offensive bursts to overcome both the opponent and the betting line.

Boston College vs. Louisville Game Info

Boston College vs Louisville starts on October 25, 2025 at 7:30 PM EST.

Venue: L&N Federal Credit Union Stadium.

Spread: Louisville -23.5
Moneyline: Boston College +1280, Louisville -3448
Over/Under: 53.5

Boston College: (1-6)  |  Louisville: (5-1)

Remi's searched hard and found the best prop for this matchup:. Prices move—always shop for the best number.

This matchup presents a clear betting-angle contrast: Louisville is outperforming expectations and covering at a high rate (83.3%), while Boston College is underperforming and struggling to cover. That dynamic suggests value may lean toward the home side, especially given Louisville’s momentum and Boston College’s difficulties. Additional intrigue comes from the offensive and defensive trends: Louisville’s upward offensive rhythm and Boston College’s defense allowing over 33 points per game create a template where Louisville could both win and cover. Conversely, Boston College will need to tighten up defensively and find offensive bursts to overcome both the opponent and the betting line.

BC trend: Boston College has covered the spread in only 2 of their 6 games so far this season, translating to roughly a 33.3% ATS cover rate.

LVILLE trend: Louisville has covered the spread in 5 of their 6 games, putting them at approximately an 83.3% ATS cover rate this season.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Boston College vs. Louisville Odds

AI algorithm Remi is pouring through tons of data on each line. In fact, anytime the Boston College vs Louisville trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance seemingly never follow normal, predictable patterns.

Boston College vs Louisville Opening Odds

BC Moneyline: +1280
LVILLE Moneyline: -3448
BC Spread: +23.5
LVILLE Spread: -23.5
Over/Under: 53.5

Boston College vs Louisville Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-370
 
-9.5 (-110)
O 55.5 (-110)
U 55.5 (-110)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-110
-106
-1.5 (-105)
+1.5 (-115)
O 50.5 (-115)
U 50.5 (-105)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-225
+188
-6.5 (-110)
+6.5 (-110)
O 56.5 (-106)
U 56.5 (-114)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4000
+1500
-27.5 (-102)
+27.5 (-120)
O 60.5 (-115)
U 60.5 (-105)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+160
-190
+4.5 (-110)
-4.5 (-110)
O 50.5 (-105)
U 50.5 (-115)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1800
+980
-21.5 (-105)
+21.5 (-115)
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-285
+230
-7.5 (-105)
+7.5 (-115)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-140
+115
-2.5 (-115)
+2.5 (-105)
O 58.5 (-110)
U 58.5 (-110)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-205
+168
-5.5 (-110)
+5.5 (-110)
O 63.5 (-106)
U 63.5 (-114)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1600
-4500
+25.5 (-110)
-25.5 (-110)
O 54.5 (-115)
U 54.5 (-105)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+230
-285
+7.5 (-118)
-7.5 (-104)
O 43.5 (-110)
U 43.5 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-450
+340
-12.5 (-110)
+12.5 (-110)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-170
+140
-3.5 (-108)
+3.5 (-112)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+610
-950
+17.5 (-115)
-17.5 (-105)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-610
 
-14.5 (-105)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+172
-210
+4.5 (-105)
-4.5 (-115)
O 54.5 (-105)
U 54.5 (-115)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+122
-146
+2.5 (+100)
-2.5 (-122)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
-110
-110
+1.5 (-115)
-1.5 (-105)
O 57.5 (-102)
U 57.5 (-120)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+300
-385
+9.5 (-104)
-9.5 (-118)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-400
+310
-10.5 (-110)
+10.5 (-110)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+122
-146
+2.5 (-102)
-2.5 (-120)
O 61.5 (-110)
U 61.5 (-110)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+275
-350
+8.5 (-110)
-8.5 (-110)
O 38.5 (-115)
U 38.5 (-105)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-520
+385
-11.5 (-118)
+11.5 (-104)
O 47.5 (-105)
U 47.5 (-115)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+122
-146
+2.5 (-104)
-2.5 (-118)
O 48.5 (-115)
U 48.5 (-105)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-225
+188
-5.5 (-120)
+5.5 (-102)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+176
-215
+5.5 (-110)
-5.5 (-110)
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 46.5 (-114)
U 46.5 (-106)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+480
-670
+15.5 (-110)
-15.5 (-110)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+146
-176
+4.5 (-115)
-4.5 (-105)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-720
 
-15.5 (-115)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-146
+122
-2.5 (-122)
+2.5 (+100)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+115
-138
+2.5 (-106)
-2.5 (-114)
O 52.5 (-110)
U 52.5 (-110)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+195
-240
+6.5 (-110)
-6.5 (-110)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+106
 
+2.5 (-115)
 
O 41.5 (-110)
U 41.5 (-110)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+310
 
+11.5 (-115)
 
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+3000
-10000
+37.5 (-108)
-37.5 (-112)
O 56.5 (-105)
U 56.5 (-115)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+152
-184
+4.5 (-115)
-4.5 (-105)
O 67.5 (-105)
U 67.5 (-115)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-275
+220
-6.5 (-122)
+6.5 (+100)
O 44.5 (-120)
U 44.5 (-102)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-670
+470
-15.5 (-112)
+15.5 (-108)
O 55.5 (-106)
U 55.5 (-114)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-108)
-33.5 (-112)
O 44.5 (-108)
U 44.5 (-112)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+270
-345
+9.5 (-110)
-9.5 (-110)
O 47.5 (-112)
U 47.5 (-108)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30.5 (-115)
-30.5 (-105)
O 45.5 (-104)
U 45.5 (-118)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+104
-125
+1.5 (-110)
-1.5 (-110)
O 63.5 (-105)
U 63.5 (-115)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-630
+450
-14.5 (-105)
+14.5 (-115)
O 48.5 (-105)
U 48.5 (-115)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-144
+120
-2.5 (-120)
+2.5 (-102)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1600
-4500
+25.5 (-110)
-25.5 (-110)
O 55.5 (-104)
U 55.5 (-118)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+184
-225
+5.5 (-104)
-5.5 (-118)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-345
+270
-9.5 (-110)
+9.5 (-110)
O 53.5 (-118)
U 53.5 (-104)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+220
-275
+7.5 (-120)
-7.5 (-102)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+375
-500
+13.5 (-110)
-13.5 (-110)
O 49.5 (-115)
U 49.5 (-105)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Boston College Eagles vs. Louisville Cardinals on October 25, 2025 at L&N Federal Credit Union Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN