SMU vs Clemson Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 18)
Updated: 2025-10-11T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The SMU Mustangs travel to face the Clemson Tigers on October 18, 2025, in a marquee nonconference matchup that pits SMU’s high-flying offense under Rhett Lashlee against Clemson’s balanced, veteran-laden squad led by Cade Klubnik. Clemson enters with home-field advantage, deep roster continuity, and high expectations, while SMU hopes to prove that last season wasn’t a fluke in its transition to the ACC.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Oct 18, 2025
Start Time: 3:30 PM EST
Venue: Memorial Stadium
Tigers Record: (3-3)
Mustangs Record: (4-2)
OPENING ODDS
SMU Moneyline: +272
CLEM Moneyline: -345
SMU Spread: +9.5
CLEM Spread: -9.5
Over/Under: 54.5
SMU
Betting Trends
- SMU has had mixed success covering as an underdog in road ACC games; when their offense is clicking and turnovers are minimal, they’ve hung close, but breakdowns have repeatedly blown games open.
CLEM
Betting Trends
- Clemson often outperforms expectations at home, especially in high-stakes matchups, leveraging crowd noise, coaching stability, and in-state recruiting depth to tilt tight games in its favor.
MATCHUP TRENDS
- This pairing historically features volatility in the total — Clemson’s mix of tempo and power run schemes contrasts with SMU’s spread speed, so live total swings will be frequent, especially if momentum shifts via turnovers or explosive plays.
SMU vs. CLEM
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: K. Jennings over 256.5 Passing Yards.
LIVE CFB ODDS
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SMU vs Clemson Prediction & Odds:
Free CFB Betting Insights for 10/18/25
The Tigers’ ability to generate interior pressure without blitzing could be a critical factor in forcing Stone into hurried throws or turnovers. Offensively, Clemson’s evolution under offensive coordinator Garrett Riley has been noticeable, as quarterback Cade Klubnik has shown improved composure and efficiency, leading an offense that thrives on rhythm and balance. The combination of running backs Phil Mafah and Jay Haynes provides both power and burst, while wideout Antonio Williams continues to be Klubnik’s most reliable target, capable of turning short passes into chain-moving gains. SMU’s defense, led by linebacker Kobe Wilson and safety Jonathan McGill, has been opportunistic but occasionally vulnerable to physical, run-heavy teams—precisely the kind of approach Clemson loves to employ to wear down opponents. Expect Clemson to test SMU’s tackling early with inside runs and play-action, while SMU will attempt to counter with speed and creativity, using tempo to prevent defensive substitutions and create mismatches in space. Special teams and turnover margin could loom large, especially if SMU manages to turn short fields into points or catch Clemson napping in transition. Ultimately, this game will likely hinge on whether SMU’s offensive tempo can outpace Clemson’s defensive physicality. If the Mustangs find early success through the air and keep the Tigers off balance, they have the firepower to make things interesting. But if Clemson controls the line of scrimmage, establishes the run, and forces Stone into predictable passing situations, the Tigers’ depth, defensive discipline, and home-field advantage could turn this into a statement victory. This matchup not only offers a fascinating contrast in styles but also serves as a potential benchmark for SMU’s legitimacy as a rising power in the ACC against one of the conference’s established giants.
Back on the road ✌️@OriginBank pic.twitter.com/nHiKflGQuM
— SMU Football (@SMUFB) October 13, 2025
SMU Mustangs CFB Preview
The SMU Mustangs enter their Week 8 matchup against the Clemson Tigers with confidence and determination, eager to prove that their high-octane offense and improved defensive identity can compete against one of the ACC’s most established powerhouses. Head coach Rhett Lashlee has built SMU into a fast, dynamic program defined by tempo, balance, and precision — and this year’s team may be his most complete yet. Quarterback Preston Stone has emerged as the heart of the offense, displaying excellent poise under pressure, strong accuracy on the move, and the ability to read coverages pre-snap. His command of Lashlee’s offense has elevated SMU’s passing game into one of the most efficient in the nation, supported by a deep receiver room headlined by Jordan Hudson, Roderick Daniels Jr., and Key’Shawn Smith. The Mustangs’ passing attack thrives on quick decision-making and spacing concepts, spreading defenses thin while forcing safeties to choose between protecting the deep ball or committing to the run. Running back Jaylan Knighton provides balance out of the backfield, capable of grinding out tough yards between the tackles or catching passes on wheel routes that test linebackers in coverage. Against Clemson’s fierce defensive front, Knighton’s versatility and SMU’s screen game will be essential tools for neutralizing the Tigers’ pass rush led by T.J. Parker and Peter Woods.
Lashlee’s game plan will likely emphasize tempo, quick reads, and play-action to keep Clemson from dictating pace and personnel. Defensively, SMU has made meaningful strides under coordinator Scott Symons, focusing on discipline and turnover creation. The Mustangs’ defense isn’t as deep as Clemson’s, but it is fast and opportunistic, led by linebacker Kobe Wilson and safety Jonathan McGill, who excel at diagnosing plays and disrupting rhythm. The defensive line’s ability to hold up against Clemson’s physical running game will be critical — particularly in containing Phil Mafah, whose combination of vision and power can punish missed tackles. SMU’s corners, including Charles Woods and Isaiah Nwokobia, will be tasked with limiting big plays from Clemson’s receivers while staying alert for Klubnik’s mobility and short-area improvisation. The Mustangs’ margin for error will be slim, but if they can generate a few takeaways, win the battle on third downs, and avoid negative plays, their offense has the firepower to trade blows with anyone. This game represents more than just a test of talent — it’s a measuring stick for SMU’s readiness to compete in the ACC spotlight. The Mustangs’ path to victory will require composure in a hostile environment, precision on offense, and the ability to finish drives in the red zone. If Stone and his receivers can strike early and force Clemson to play from behind, SMU has a legitimate chance to make national noise with an upset that would resonate far beyond Week 8.
Credit: USA TODAY/IMAGN
Clemson Tigers CFB Preview
The Clemson Tigers return to Death Valley for their Week 8 matchup against SMU with the confidence of a team that knows how to dominate on its home turf, where they’ve turned Memorial Stadium into one of the most intimidating environments in college football. Under head coach Dabo Swinney, Clemson’s program has evolved into a model of consistency — fueled by elite recruiting, disciplined execution, and a roster deep enough to contend with anyone in the country. Quarterback Cade Klubnik remains the centerpiece of the offense, showcasing impressive command and maturity in Garrett Riley’s system. Klubnik’s ability to read defenses, extend plays, and deliver accurate throws under pressure has allowed Clemson to operate with fluidity and efficiency. The Tigers’ passing attack, featuring standout wide receiver Antonio Williams and emerging sophomore Tyler Brown, thrives on rhythm routes and spacing concepts that stretch defenses horizontally and vertically. Complementing the air attack is running back Phil Mafah, whose powerful running style and exceptional balance between the tackles have made him one of the ACC’s most reliable rushers. Clemson’s offensive line, anchored by veterans such as Walker Parks and Tristan Leigh, has continued to improve in both pass protection and run-blocking metrics, giving the Tigers the flexibility to attack defenses with balance and tempo. Defensively, Clemson remains one of the most fearsome units in the country, led by a dominant front seven that relentlessly pressures opposing quarterbacks and disrupts the run game.
Edge rusher T.J. Parker has become the team’s defensive anchor, combining speed, strength, and technique to wreak havoc in the backfield, while defensive tackle Peter Woods provides interior push that collapses pockets and eliminates running lanes. Linebackers Barrett Carter and Wade Woodaz bring versatility, capable of blitzing, covering tight ends, and tracking mobile quarterbacks like SMU’s Preston Stone. In the secondary, safety Andrew Mukuba’s leadership and range give Clemson confidence against deep passing attacks, while the corners play with aggression and physicality at the line of scrimmage. Expect defensive coordinator Wes Goodwin to dial up a mix of disguised pressures and zone looks to keep SMU’s up-tempo offense uncomfortable and out of rhythm. Special teams, often overlooked, could also play a major role in this contest — kicker Robert Gunn III has the range to flip field position, and Clemson’s return units consistently create momentum-shifting plays. The Tigers’ formula for victory will be familiar: establish dominance at the line of scrimmage, control time of possession, and capitalize on turnovers. If Klubnik avoids mistakes and Clemson’s defensive front neutralizes SMU’s tempo, the Tigers should be able to dictate the flow and force the Mustangs into unfavorable passing downs. This game not only gives Clemson an opportunity to reinforce its status as a national contender but also to send a message about its adaptability and depth against one of the ACC’s newest and most explosive offenses. With the Death Valley crowd behind them, the Tigers will look to combine precision, pressure, and poise to extend their home-field dominance and inch closer to another College Football Playoff push.
Beyond the blowout: 3 Tigers who demanded a bigger role in win over BC https://t.co/Ei86mCfc11
— Rubbing The Rock (@RubbingTheRock) October 13, 2025
SMU vs. Clemson Prop Picks (AI)
SMU vs. Clemson Prediction (AI)
Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every simulation between the Mustangs and Tigers and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most focused on the growing weight human bettors tend to put on SMU’s strength factors between a Mustangs team going up against a possibly healthy Tigers team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI SMU vs Clemson picks, computer picks Mustangs vs Tigers, best bets, model edges, confidence ratings.
| DATE | GAME | LEAN | %WIN | UNITS | LEVEL | |
|---|---|---|---|---|---|---|
| CFB | 11/11 | KENTST@AKRON | UNLOCK THIS PICK | 5 |
EXECUTIVE
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Mustangs Betting Trends
SMU has had mixed success covering as an underdog in road ACC games; when their offense is clicking and turnovers are minimal, they’ve hung close, but breakdowns have repeatedly blown games open.
Tigers Betting Trends
Clemson often outperforms expectations at home, especially in high-stakes matchups, leveraging crowd noise, coaching stability, and in-state recruiting depth to tilt tight games in its favor.
Mustangs vs. Tigers Matchup Trends
This pairing historically features volatility in the total — Clemson’s mix of tempo and power run schemes contrasts with SMU’s spread speed, so live total swings will be frequent, especially if momentum shifts via turnovers or explosive plays.
SMU vs. Clemson Game Info
What time does SMU vs Clemson start on October 18, 2025?
SMU vs Clemson starts on October 18, 2025 at 3:30 PM EST.
Where is SMU vs Clemson being played?
Venue: Memorial Stadium.
What are the opening odds for SMU vs Clemson?
Spread: Clemson -9.5
Moneyline: SMU +272, Clemson -345
Over/Under: 54.5
What are the records for SMU vs Clemson?
SMU: (4-2) | Clemson: (3-3)
What is the AI best bet for SMU vs Clemson?
Remi's searched hard and found the best prop for this matchup: K. Jennings over 256.5 Passing Yards.. Prices move—always shop for the best number.
What are SMU vs Clemson trending bets?
This pairing historically features volatility in the total — Clemson’s mix of tempo and power run schemes contrasts with SMU’s spread speed, so live total swings will be frequent, especially if momentum shifts via turnovers or explosive plays.
What are SMU trending bets?
SMU trend: SMU has had mixed success covering as an underdog in road ACC games; when their offense is clicking and turnovers are minimal, they’ve hung close, but breakdowns have repeatedly blown games open.
What are Clemson trending bets?
CLEM trend: Clemson often outperforms expectations at home, especially in high-stakes matchups, leveraging crowd noise, coaching stability, and in-state recruiting depth to tilt tight games in its favor.
Where can I find AI Picks for SMU vs Clemson?
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
SMU vs. Clemson Odds
Remi is pouring through tons of data on each player. In fact, anytime the SMU vs Clemson trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable patterns.
SMU vs Clemson Opening Odds
SMU Moneyline:
+272 CLEM Moneyline: -345
SMU Spread: +9.5
CLEM Spread: -9.5
Over/Under: 54.5
SMU vs Clemson Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Nov 11, 2025 7:30PM EST
Kent State Golden Flashes
Akron Zips
11/11/25 7:30PM
KENT
AKRON
|
–
–
|
+235
-285
|
+7 (-105)
-7 (-115)
|
O 49 (-110)
U 49 (-110)
|
|
|
Nov 11, 2025 8:00PM EST
Ohio Bobcats
Western Michigan Broncos
11/11/25 8PM
OHIO
WMICH
|
–
–
|
-110
-110
|
+1 (-110)
-1 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
|
Nov 12, 2025 7:00PM EST
Northern Illinois Huskies
Umass Minutemen
11/12/25 7PM
NILL
UMASS
|
–
–
|
-440
|
-11 (-110)
|
O 43.5 (-115)
U 43.5 (-105)
|
|
|
Nov 12, 2025 7:00PM EST
Buffalo Bulls
Central Michigan Chippewas
11/12/25 7PM
BUFF
CMICH
|
–
–
|
+100
-120
|
+1.5 (-115)
-1.5 (-105)
|
O 44 (-105)
U 44 (-115)
|
|
|
Nov 12, 2025 7:00PM EST
Toledo Rockets
Miami Ohio Redhawks
11/12/25 7PM
TOLEDO
MIAOH
|
–
–
|
-195
|
-4 (-110)
|
O 45 (-110)
U 45 (-110)
|
|
|
Nov 13, 2025 7:30PM EST
Troy Trojans
Old Dominion Monarchs
11/13/25 7:30PM
TROY
OLDDOM
|
–
–
|
+325
-435
|
+11.5 (-110)
-11.5 (-110)
|
O 52.5 (-110)
U 52.5 (-110)
|
|
|
Nov 14, 2025 7:30PM EST
Clemson Tigers
Louisville Cardinals
11/14/25 7:30PM
CLEM
LVILLE
|
–
–
|
+120
-140
|
+3 (-120)
-3 (+100)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
|
Nov 14, 2025 9:00PM EST
Minnesota Golden Gophers
Oregon Ducks
11/14/25 9PM
MINN
OREG
|
–
–
|
+1100
-2800
|
+25.5 (-105)
-25.5 (-115)
|
O 44 (-110)
U 44 (-110)
|
|
|
Nov 15, 2025 12:00PM EST
Air Force Falcons
UConn Huskies
11/15/25 12PM
AF
UCONN
|
–
–
|
+235
-285
|
+7 (-105)
-7 (-115)
|
O 63.5 (-110)
U 63.5 (-110)
|
|
|
Nov 15, 2025 12:00PM EST
Michigan Wolverines
Northwestern Wildcats
11/15/25 12PM
MICH
NWEST
|
–
–
|
-600
+430
|
-11.5 (-110)
+11.5 (-110)
|
O 41 (-110)
U 41 (-110)
|
|
|
Nov 15, 2025 12:00PM EST
UTSA Roadrunners
Charlotte 49ers
11/15/25 12PM
UTSA
CHARLO
|
–
–
|
-1100
+650
|
-18.5 (-110)
+18.5 (-110)
|
O 60 (-110)
U 60 (-110)
|
|
|
Nov 15, 2025 12:00PM EST
South Florida Bulls
Navy Midshipmen
11/15/25 12PM
SFLA
NAVY
|
–
–
|
-400
+300
|
-10.5 (-105)
+10.5 (-115)
|
O 65 (-110)
U 65 (-110)
|
|
|
Nov 15, 2025 12:00PM EST
Arizona Wildcats
Cincinnati Bearcats
11/15/25 12PM
ARIZ
CINCY
|
–
–
|
+185
-225
|
+6 (-105)
-6 (-115)
|
O 56 (-110)
U 56 (-110)
|
|
|
Nov 15, 2025 12:00PM EST
Eastern Michigan Eagles
Ball State Cardinals
11/15/25 12PM
EMICH
BALLST
|
–
–
|
-130
+110
|
-2.5 (-110)
+2.5 (-110)
|
O 50.5 (-105)
U 50.5 (-115)
|
|
|
Nov 15, 2025 12:00PM EST
Notre Dame Fighting Irish
Pittsburgh Panthers
11/15/25 12PM
ND
PITT
|
–
–
|
-450
+335
|
-11 (-110)
+11 (-110)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
|
Nov 15, 2025 12:00PM EST
South Carolina Gamecocks
Texas A&M Aggies
11/15/25 12PM
SC
TEXAM
|
–
–
|
+700
-1200
|
+19.5 (-110)
-19.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Nov 15, 2025 12:00PM EST
Wisconsin Badgers
Indiana Hoosiers
11/15/25 12PM
WISC
IND
|
–
–
|
+3500
-20000
|
+30 (-120)
-30 (+100)
|
O 44 (-110)
U 44 (-110)
|
|
|
Nov 15, 2025 12:00PM EST
Kansas State Wildcats
Oklahoma State Cowboys
11/15/25 12PM
KSTATE
OKLAST
|
–
–
|
-1300
+725
|
-19.5 (-110)
+19.5 (-110)
|
O 52.5 (+100)
U 52.5 (-120)
|
|
|
Nov 15, 2025 12:45PM EST
Arkansas Razorbacks
LSU Tigers
11/15/25 12:45PM
ARK
LSU
|
–
–
|
+170
-200
|
+5.5 (-110)
-5.5 (-110)
|
O 56.5 (-105)
U 56.5 (-115)
|
|
|
Nov 15, 2025 1:00PM EST
Oregon State Beavers
Tulsa Golden Hurricane
11/15/25 1PM
OREGST
TULSA
|
–
–
|
-125
+105
|
-2.5 (-110)
+2.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Nov 15, 2025 1:00PM EST
West Virginia Mountaineers
Arizona State Sun Devils
11/15/25 1PM
WVU
ARIZST
|
–
–
|
+335
-450
|
+11.5 (-105)
-11.5 (-115)
|
O 48 (-110)
U 48 (-110)
|
|
|
Nov 15, 2025 1:30PM EST
Tennessee Tech Golden Eagles
Kentucky Wildcats
11/15/25 1:30PM
TNTECH
UK
|
–
–
|
+890
-1700
|
+20.5 (-115)
-20.5 (-105)
|
O 52.5 (-105)
U 52.5 (-115)
|
|
|
Nov 15, 2025 2:00PM EST
Marshall Thundering Herd
Georgia State Panthers
11/15/25 2PM
MARSH
GAST
|
–
–
|
-300
+250
|
-7.5 (-110)
+7.5 (-110)
|
O 63.5 (-110)
U 63.5 (-110)
|
|
|
Nov 15, 2025 2:00PM EST
North Texas Mean Green
UAB Blazers
11/15/25 2PM
NOTEX
UAB
|
–
–
|
-1100
+650
|
-19 (-110)
+19 (-110)
|
O 69.5 (-105)
U 69.5 (-115)
|
|
|
Nov 15, 2025 3:00PM EST
UTEP Miners
Missouri State Bears
11/15/25 3PM
UTEP
MIZZST
|
–
–
|
+165
-195
|
+4 (-105)
-4 (-115)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Nov 15, 2025 3:00PM EST
Colorado State Rams
New Mexico Lobos
11/15/25 3PM
COLOST
NMEX
|
–
–
|
+430
-625
|
+14 (-105)
-14 (-115)
|
O 54 (-110)
U 54 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
San Jose State Spartans
Nevada Wolf Pack
11/15/25 3:30PM
SJST
NEVADA
|
–
–
|
-340
+270
|
-9.5 (-110)
+9.5 (-110)
|
O 52 (-110)
U 52 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
South Alabama Jaguars
UL Monroe Warhawks
11/15/25 3:30PM
SBAMA
MONROE
|
–
–
|
-200
+170
|
-4.5 (-110)
+4.5 (-110)
|
O 51 (-110)
U 51 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
UCF Knights
Texas Tech Red Raiders
11/15/25 3:30PM
UCF
TXTECH
|
–
–
|
+1000
-2500
|
+24 (-110)
-24 (-110)
|
O 47.5 (-115)
U 47.5 (-105)
|
|
|
Nov 15, 2025 3:30PM EST
NC State Wolfpack
Miami Hurricanes
11/15/25 3:30PM
NCST
MIAMI
|
–
–
|
+430
-625
|
+14.5 (-110)
-14.5 (-110)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Maryland Terrapins
Illinois Fighting Illini
11/15/25 3:30PM
MD
ILL
|
–
–
|
+460
-675
|
+15 (-110)
-15 (-110)
|
O 53 (-110)
U 53 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Georgia Tech Yellow Jackets
Boston College Eagles
11/15/25 3:30PM
GATECH
BC
|
–
–
|
-850
+550
|
-16.5 (-110)
+16.5 (-110)
|
O 58.5 (-110)
U 58.5 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Penn State Nittany Lions
Michigan State Spartans
11/15/25 3:30PM
PSU
MICHST
|
–
–
|
-260
+215
|
-7 (-115)
+7 (-105)
|
O 49 (-110)
U 49 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
MTSU Blue Raiders
Western Kentucky Hilltoppers
11/15/25 3:30PM
MTSU
WKY
|
–
–
|
-550
|
-13.5 (-115)
|
O 56 (-110)
U 56 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Virginia Cavaliers
Duke Blue Devils
11/15/25 3:30PM
UVA
DUKE
|
–
–
|
+190
-230
|
+6 (-105)
-6 (-115)
|
O 57.5 (-105)
U 57.5 (-115)
|
|
|
Nov 15, 2025 3:30PM EST
Iowa Hawkeyes
USC Trojans
11/15/25 3:30PM
IOWA
USC
|
–
–
|
+200
-240
|
+6.5 (-105)
-6.5 (-115)
|
O 49.5 (-115)
U 49.5 (-105)
|
|
|
Nov 15, 2025 3:30PM EST
App State Mountaineers
James Madison Dukes
11/15/25 3:30PM
APPST
JMAD
|
–
–
|
-1600
|
-21 (-110)
|
O 54 (-105)
U 54 (-115)
|
|
|
Nov 15, 2025 3:30PM EST
Texas State Bobcats
USM Golden Eagles
11/15/25 3:30PM
TEXST
USM
|
–
–
|
+160
|
+4.5 (-110)
|
O 65.5 (-110)
U 65.5 (-110)
|
|
|
Nov 15, 2025 3:30PM EST
Oklahoma Sooners
Alabama Crimson Tide
11/15/25 3:30PM
OKLA
BAMA
|
–
–
|
+180
-220
|
+6 (-115)
-6 (-105)
|
O 46 (-110)
U 46 (-110)
|
|
|
Nov 15, 2025 4:00PM EST
Florida Atlantic Owls
Tulane Green Wave
11/15/25 4PM
FAU
TULANE
|
–
–
|
+600
-950
|
+17.5 (-105)
-17.5 (-115)
|
O 63.5 (-105)
U 63.5 (-115)
|
|
|
Nov 15, 2025 4:00PM EST
Memphis Tigers
East Carolina Pirates
11/15/25 4PM
MEMP
ECAR
|
–
–
|
+120
-140
|
+2.5 (+100)
-2.5 (-120)
|
O 59.5 (-110)
U 59.5 (-110)
|
|
|
Nov 15, 2025 4:15PM EST
New Mexico State Aggies
Tennessee Volunteers
11/15/25 4:15PM
NMEXST
TENN
|
–
–
|
+8000
-50000
|
+39.5 (-105)
-39.5 (-115)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
|
Nov 15, 2025 4:30PM EST
North Carolina Tar Heels
Wake Forest Demon Deacons
11/15/25 4:30PM
UNC
WAKE
|
–
–
|
+185
-225
|
+6.5 (-115)
-6.5 (-105)
|
O 39 (-110)
U 39 (-110)
|
|
|
Nov 15, 2025 5:00PM EST
Liberty Flames
FIU Panthers
11/15/25 5PM
LIB
FIU
|
–
–
|
-140
|
-3 (+100)
|
O 52 (-110)
U 52 (-110)
|
|
|
Nov 15, 2025 6:00PM EST
Coastal Carolina Chanticleers
Georgia Southern Eagles
11/15/25 6PM
COAST
GASO
|
–
–
|
+115
-135
|
+2.5 (-105)
-2.5 (-115)
|
O 60.5 (-110)
U 60.5 (-110)
|
|
|
Nov 15, 2025 7:00PM EST
Utah State Aggies
UNLV Rebels
11/15/25 7PM
UTAHST
UNLV
|
–
–
|
+200
-240
|
+6 (-110)
-6 (-110)
|
O 71 (-110)
U 71 (-110)
|
|
|
Nov 15, 2025 7:00PM EST
Florida Gators
Ole Miss Rebels
11/15/25 7PM
FLA
OLEMISS
|
–
–
|
+475
-700
|
+16 (-110)
-16 (-110)
|
O 54 (-110)
U 54 (-110)
|
|
|
Nov 15, 2025 7:00PM EST
Delaware Blue Hens
Sam Houston State Bearkats
11/15/25 7PM
DEL
SAMST
|
–
–
|
-360
+280
|
-9.5 (-115)
+9.5 (-105)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
|
Nov 15, 2025 7:00PM EST
Utah Utes
Baylor Bears
11/15/25 7PM
UTAH
BAYLOR
|
–
–
|
-310
+255
|
-8 (-110)
+8 (-110)
|
O 60 (-105)
U 60 (-115)
|
|
|
Nov 15, 2025 7:00PM EST
Purdue Boilermakers
Washington Huskies
11/15/25 7PM
PURDUE
WASH
|
–
–
|
+575
-900
|
+17 (-110)
-17 (-110)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
|
Nov 15, 2025 7:30PM EST
Virginia Tech Hokies
Florida State Seminoles
11/15/25 7:30PM
VATECH
FSU
|
–
–
|
+400
-575
|
+13.5 (-105)
-13.5 (-115)
|
O 55 (-110)
U 55 (-110)
|
|
|
Nov 15, 2025 7:30PM EST
Texas Longhorns
Georgia Bulldogs
11/15/25 7:30PM
TEXAS
UGA
|
–
–
|
+180
-220
|
+6 (-115)
-6 (-105)
|
O 48 (-110)
U 48 (-110)
|
|
|
Nov 15, 2025 7:30PM EST
UCLA Bruins
Ohio State Buckeyes
11/15/25 7:30PM
UCLA
OHIOST
|
–
–
|
+2800
-10000
|
+31.5 (+100)
-31.5 (-120)
|
O 49 (-110)
U 49 (-110)
|
|
|
Nov 15, 2025 7:45PM EST
Mississippi State Bulldogs
Missouri Tigers
11/15/25 7:45PM
MISSST
MIZZOU
|
–
–
|
+215
-260
|
+7 (-110)
-7 (-110)
|
O 51 (-110)
U 51 (-110)
|
|
|
Nov 15, 2025 8:00PM EST
Kennesaw State Owls
Jacksonville State Gamecocks
11/15/25 8PM
KENSAW
JAXST
|
–
–
|
-160
+135
|
-3.5 (+100)
+3.5 (-120)
|
O 54 (-110)
U 54 (-110)
|
|
|
Nov 15, 2025 10:00PM EST
Louisiana Tech Bulldogs
Washington State Cougars
11/15/25 10PM
LATECH
WASHST
|
–
–
|
+260
-320
|
+8.5 (-105)
-8.5 (-115)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
|
Nov 15, 2025 10:15PM EST
TCU Horned Frogs
BYU Cougars
11/15/25 10:15PM
TCU
BYU
|
–
–
|
+160
-185
|
+4.5 (-110)
-4.5 (-110)
|
O 51.5 (-115)
U 51.5 (-105)
|
|
|
Nov 15, 2025 10:30PM EST
Boise State Broncos
San Diego State Aztecs
11/15/25 10:30PM
BOISE
SDGST
|
–
–
|
+120
-140
|
+3 (-115)
-3 (-105)
|
O 41 (-110)
U 41 (-110)
|
|
|
Nov 15, 2025 10:30PM EST
Wyoming Cowboys
Fresno State Bulldogs
11/15/25 10:30PM
WYO
FRESNO
|
–
–
|
+145
-170
|
+3.5 (-120)
-3.5 (+100)
|
O 40.5 (-110)
U 40.5 (-110)
|
|
|
Nov 22, 2025 12:00PM EST
USC Trojans
Oregon Ducks
11/22/25 12PM
USC
OREG
|
–
–
|
+176
-215
|
+6.5 (-115)
-6.5 (-105)
|
O 55.5 (-105)
U 55.5 (-115)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers SMU Mustangs vs. Clemson Tigers on October 18, 2025 at Memorial Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
| LEAN | %WIN | UNITS | RESULT | |
|---|---|---|---|---|
| JAXST@UTEP | JAXST -105 | 57.0% | 7 | WIN |
| FSU@CLEM | CLEM -118 | 57.1% | 5 | WIN |
| UNLV@COLOST | UNLV -4 | 55.2% | 5 | WIN |
| OREG@IOWA | IOWA +6.5 | 53.3% | 2 | WIN |
| NEB@UCLA | NEB +1.5 | 55.8% | 5 | WIN |
| AUBURN@VANDY | AUBURN +6.5 | 56.2% | 6 | LOSS |
| KENSAW@NMEXST | NMEXST +10 | 56.5% | 6 | WIN |
| STNFRD@UNC | STNFRD +7.5 | 53.8% | 3 | WIN |
| DUKE@UCONN | UCONN +8.5 | 57.9% | 7 | WIN |
| NEVADA@UTAHST | NEVADA +9.5 | 55.9% | 5 | LOSS |
| SAMST@OREGST | SAMST +21 | 57.7% | 7 | WIN |
| NEB@UCLA | NICO IAMALEAVA UNDER 180.5 PASS YDS | 56.6% | 6 | LOSS |
| HOU@UCF | HOU -112 | 58.0% | 6 | WIN |
| GASTHRN@APPST | GASTHRN +180 | 36.5% | 2 | WIN |
| KENTST@BALLST | BALLST -2.5 | 54.5% | 4 | WIN |
| WAKE@FSU | WAKE +10.5 | 56.4% | 6 | LOSS |
| WYO@SDGST | SDGST -10.5 | 56.7% | 7 | WIN |
| OKLA@TENN | TENN -130 | 58.3% | 5 | LOSS |
| GATECH@NCST | GATECH -5 | 56.4% | 6 | LOSS |
| MIAMI@SMU | MIAMI -10 | 54.3% | 4 | LOSS |
| DEL@LIB | DEL +3.5 | 57.6% | 7 | LOSS |
| NMEXST@WKY | NMEXST +8.5 | 57.9% | 7 | LOSS |
| IND@MD | MD +21.5 | 54.6% | 4 | LOSS |
| CINCY@UTAH | CINCY +11 | 57.6% | 7 | LOSS |
| OLDDOM@LAMON | LAMON +17 | 58.4% | 8 | LOSS |
| VANDY@TEXAS | OVER 46.5 | 53.7% | 2 | WIN |
| MICHST@MINN | MAKHI FRAZIER UNDER 52.5 RUSH YDS | 55.2% | 5 | WIN |
| UNC@CUSE | UNC +110 | 50.4% | 2 | WIN |
| MRSHL@COASTAL | COASTAL +7 | 53.3% | 3 | WIN |
| FIU@MIZZST | FIU +3.5 | 53.9% | 3 | LOSS |
| TEXAM@LSU | MARCEL REED OVER 0.5 INT | 55.5% | 5 | WIN |
| RUT@PURDUE | RUT +103 | 54.0% | 4 | WIN |
| TOLEDO@WASHST | TOLEDO -110 | 56.1% | 6 | LOSS |
| AUBURN@ARK | ARK -128 | 60.5% | 8 | LOSS |
| NCST@PITT | NCST +6.5 | 54.9% | 4 | LOSS |
| OHIO@EMICH | EMICH +12 | 54.1% | 4 | WIN |
| TCU@WVU | WVU +16.5 | 54.6% | 4 | WIN |
| COLO@UTAH | COLO +14.5 | 57.7% | 7 | LOSS |
| HOU@ARIZST | HOU +7.5 | 57.1% | 7 | WIN |
| UVA@UNC | UNC +11.5 | 56.2% | 6 | WIN |
| MINN@IOWA | MINN +9.5 | 57.3% | 7 | LOSS |
| UCONN@RICE | RICE +10.5 | 57.1% | 6 | WIN |
| FAU@NAVY | FAU +14.5 | 56.7% | 6 | WIN |
| LAMON@USM | LAMON +13.5 | 56.4% | 6 | LOSS |
| BOISE@NEVADA | NEVADA +21.5 | 56.8% | 6 | WIN |
| SALA@GAST | GAST +6.5 | 54.3% | 4 | LOSS |
| MIZZST@NMEXST | MIZZST -108 | 54.4% | 4 | WIN |
| KENSAW@FIU | FIU +3 | 53.7% | 3 | LOSS |
| KENTST@TOLEDO | KENTST +24.5 | 56.9% | 6 | LOSS |
| OLDDOM@JMAD | JMAD -125 | 57.9% | 7 | WIN |
| TXTECH@ARIZST | TXTECH -6.5 | 54.2% | 4 | LOSS |