SMU vs Clemson Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 18)

Updated: 2025-10-11T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The SMU Mustangs travel to face the Clemson Tigers on October 18, 2025, in a marquee nonconference matchup that pits SMU’s high-flying offense under Rhett Lashlee against Clemson’s balanced, veteran-laden squad led by Cade Klubnik. Clemson enters with home-field advantage, deep roster continuity, and high expectations, while SMU hopes to prove that last season wasn’t a fluke in its transition to the ACC.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 18, 2025

Start Time: 3:30 PM EST​

Venue: Memorial Stadium​

Tigers Record: (3-3)

Mustangs Record: (4-2)

OPENING ODDS

SMU Moneyline: +272

CLEM Moneyline: -345

SMU Spread: +9.5

CLEM Spread: -9.5

Over/Under: 54.5

SMU
Betting Trends

  • SMU has had mixed success covering as an underdog in road ACC games; when their offense is clicking and turnovers are minimal, they’ve hung close, but breakdowns have repeatedly blown games open.

CLEM
Betting Trends

  • Clemson often outperforms expectations at home, especially in high-stakes matchups, leveraging crowd noise, coaching stability, and in-state recruiting depth to tilt tight games in its favor.

MATCHUP TRENDS

  • This pairing historically features volatility in the total — Clemson’s mix of tempo and power run schemes contrasts with SMU’s spread speed, so live total swings will be frequent, especially if momentum shifts via turnovers or explosive plays.

SMU vs. CLEM
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: K. Jennings over 256.5 Passing Yards.

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SMU vs Clemson Prediction & Odds:
Free CFB Betting Insights for 10/18/25

The Week 8 clash between the SMU Mustangs and the Clemson Tigers on October 18, 2025, stands out as one of the more intriguing nonconference matchups of the season, featuring two programs built on contrasting philosophies but both capable of explosive offensive performances. SMU enters this contest under head coach Rhett Lashlee with a fast-paced, aggressive offensive system designed to spread the field, utilize tempo, and test opposing secondaries with vertical shots and quick strikes. Quarterback Preston Stone has developed into a steady and composed leader for the Mustangs, combining efficient decision-making with strong command of the passing game. His chemistry with standout receiver Jordan Hudson and tight end Roderick Daniels Jr. has given SMU the kind of offensive balance that forces defenses to defend every blade of grass. However, the challenge they face in Death Valley will be unlike any they’ve encountered this season. Clemson’s defense remains among the nation’s elite, anchored by a front seven that consistently overwhelms offensive lines and disrupts timing before plays can fully develop. Edge rusher T.J. Parker and interior force Peter Woods headline a defensive unit that has dominated opponents in both the run and pass game, while linebacker Barrett Carter provides elite versatility as both a pass rusher and coverage defender.

The Tigers’ ability to generate interior pressure without blitzing could be a critical factor in forcing Stone into hurried throws or turnovers. Offensively, Clemson’s evolution under offensive coordinator Garrett Riley has been noticeable, as quarterback Cade Klubnik has shown improved composure and efficiency, leading an offense that thrives on rhythm and balance. The combination of running backs Phil Mafah and Jay Haynes provides both power and burst, while wideout Antonio Williams continues to be Klubnik’s most reliable target, capable of turning short passes into chain-moving gains. SMU’s defense, led by linebacker Kobe Wilson and safety Jonathan McGill, has been opportunistic but occasionally vulnerable to physical, run-heavy teams—precisely the kind of approach Clemson loves to employ to wear down opponents. Expect Clemson to test SMU’s tackling early with inside runs and play-action, while SMU will attempt to counter with speed and creativity, using tempo to prevent defensive substitutions and create mismatches in space. Special teams and turnover margin could loom large, especially if SMU manages to turn short fields into points or catch Clemson napping in transition. Ultimately, this game will likely hinge on whether SMU’s offensive tempo can outpace Clemson’s defensive physicality. If the Mustangs find early success through the air and keep the Tigers off balance, they have the firepower to make things interesting. But if Clemson controls the line of scrimmage, establishes the run, and forces Stone into predictable passing situations, the Tigers’ depth, defensive discipline, and home-field advantage could turn this into a statement victory. This matchup not only offers a fascinating contrast in styles but also serves as a potential benchmark for SMU’s legitimacy as a rising power in the ACC against one of the conference’s established giants.

SMU Mustangs CFB Preview

The SMU Mustangs enter their Week 8 matchup against the Clemson Tigers with confidence and determination, eager to prove that their high-octane offense and improved defensive identity can compete against one of the ACC’s most established powerhouses. Head coach Rhett Lashlee has built SMU into a fast, dynamic program defined by tempo, balance, and precision — and this year’s team may be his most complete yet. Quarterback Preston Stone has emerged as the heart of the offense, displaying excellent poise under pressure, strong accuracy on the move, and the ability to read coverages pre-snap. His command of Lashlee’s offense has elevated SMU’s passing game into one of the most efficient in the nation, supported by a deep receiver room headlined by Jordan Hudson, Roderick Daniels Jr., and Key’Shawn Smith. The Mustangs’ passing attack thrives on quick decision-making and spacing concepts, spreading defenses thin while forcing safeties to choose between protecting the deep ball or committing to the run. Running back Jaylan Knighton provides balance out of the backfield, capable of grinding out tough yards between the tackles or catching passes on wheel routes that test linebackers in coverage. Against Clemson’s fierce defensive front, Knighton’s versatility and SMU’s screen game will be essential tools for neutralizing the Tigers’ pass rush led by T.J. Parker and Peter Woods.

Lashlee’s game plan will likely emphasize tempo, quick reads, and play-action to keep Clemson from dictating pace and personnel. Defensively, SMU has made meaningful strides under coordinator Scott Symons, focusing on discipline and turnover creation. The Mustangs’ defense isn’t as deep as Clemson’s, but it is fast and opportunistic, led by linebacker Kobe Wilson and safety Jonathan McGill, who excel at diagnosing plays and disrupting rhythm. The defensive line’s ability to hold up against Clemson’s physical running game will be critical — particularly in containing Phil Mafah, whose combination of vision and power can punish missed tackles. SMU’s corners, including Charles Woods and Isaiah Nwokobia, will be tasked with limiting big plays from Clemson’s receivers while staying alert for Klubnik’s mobility and short-area improvisation. The Mustangs’ margin for error will be slim, but if they can generate a few takeaways, win the battle on third downs, and avoid negative plays, their offense has the firepower to trade blows with anyone. This game represents more than just a test of talent — it’s a measuring stick for SMU’s readiness to compete in the ACC spotlight. The Mustangs’ path to victory will require composure in a hostile environment, precision on offense, and the ability to finish drives in the red zone. If Stone and his receivers can strike early and force Clemson to play from behind, SMU has a legitimate chance to make national noise with an upset that would resonate far beyond Week 8.

The SMU Mustangs travel to face the Clemson Tigers on October 18, 2025, in a marquee nonconference matchup that pits SMU’s high-flying offense under Rhett Lashlee against Clemson’s balanced, veteran-laden squad led by Cade Klubnik. Clemson enters with home-field advantage, deep roster continuity, and high expectations, while SMU hopes to prove that last season wasn’t a fluke in its transition to the ACC. SMU vs Clemson AI Prediction: Free CFB Betting Insights for Oct 18. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Clemson Tigers CFB Preview

The Clemson Tigers return to Death Valley for their Week 8 matchup against SMU with the confidence of a team that knows how to dominate on its home turf, where they’ve turned Memorial Stadium into one of the most intimidating environments in college football. Under head coach Dabo Swinney, Clemson’s program has evolved into a model of consistency — fueled by elite recruiting, disciplined execution, and a roster deep enough to contend with anyone in the country. Quarterback Cade Klubnik remains the centerpiece of the offense, showcasing impressive command and maturity in Garrett Riley’s system. Klubnik’s ability to read defenses, extend plays, and deliver accurate throws under pressure has allowed Clemson to operate with fluidity and efficiency. The Tigers’ passing attack, featuring standout wide receiver Antonio Williams and emerging sophomore Tyler Brown, thrives on rhythm routes and spacing concepts that stretch defenses horizontally and vertically. Complementing the air attack is running back Phil Mafah, whose powerful running style and exceptional balance between the tackles have made him one of the ACC’s most reliable rushers. Clemson’s offensive line, anchored by veterans such as Walker Parks and Tristan Leigh, has continued to improve in both pass protection and run-blocking metrics, giving the Tigers the flexibility to attack defenses with balance and tempo. Defensively, Clemson remains one of the most fearsome units in the country, led by a dominant front seven that relentlessly pressures opposing quarterbacks and disrupts the run game.

Edge rusher T.J. Parker has become the team’s defensive anchor, combining speed, strength, and technique to wreak havoc in the backfield, while defensive tackle Peter Woods provides interior push that collapses pockets and eliminates running lanes. Linebackers Barrett Carter and Wade Woodaz bring versatility, capable of blitzing, covering tight ends, and tracking mobile quarterbacks like SMU’s Preston Stone. In the secondary, safety Andrew Mukuba’s leadership and range give Clemson confidence against deep passing attacks, while the corners play with aggression and physicality at the line of scrimmage. Expect defensive coordinator Wes Goodwin to dial up a mix of disguised pressures and zone looks to keep SMU’s up-tempo offense uncomfortable and out of rhythm. Special teams, often overlooked, could also play a major role in this contest — kicker Robert Gunn III has the range to flip field position, and Clemson’s return units consistently create momentum-shifting plays. The Tigers’ formula for victory will be familiar: establish dominance at the line of scrimmage, control time of possession, and capitalize on turnovers. If Klubnik avoids mistakes and Clemson’s defensive front neutralizes SMU’s tempo, the Tigers should be able to dictate the flow and force the Mustangs into unfavorable passing downs. This game not only gives Clemson an opportunity to reinforce its status as a national contender but also to send a message about its adaptability and depth against one of the ACC’s newest and most explosive offenses. With the Death Valley crowd behind them, the Tigers will look to combine precision, pressure, and poise to extend their home-field dominance and inch closer to another College Football Playoff push.

SMU vs. Clemson Prop Picks (AI)

AI algorithm Remi is pouring through tons of stats on each team. In fact, anytime the Mustangs and Tigers play there’s always several intriguing angles to key in on. Not to mention games played at Memorial Stadium in Oct can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: K. Jennings over 256.5 Passing Yards.

SMU vs. Clemson Prediction (AI)

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Remi, our AI sports genius, has been pouring over tons of data from every angle between the Mustangs and Tigers and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most focused on the growing factor emotional bettors tend to put on coaching factors between a Mustangs team going up against a possibly healthy Tigers team. In reality, the true game analytics might reflect a strong lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI SMU vs Clemson picks, computer picks Mustangs vs Tigers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Mustangs Betting Trends

SMU has had mixed success covering as an underdog in road ACC games; when their offense is clicking and turnovers are minimal, they’ve hung close, but breakdowns have repeatedly blown games open.

Tigers Betting Trends

Clemson often outperforms expectations at home, especially in high-stakes matchups, leveraging crowd noise, coaching stability, and in-state recruiting depth to tilt tight games in its favor.

Mustangs vs. Tigers Matchup Trends

This pairing historically features volatility in the total — Clemson’s mix of tempo and power run schemes contrasts with SMU’s spread speed, so live total swings will be frequent, especially if momentum shifts via turnovers or explosive plays.

SMU vs. Clemson Game Info

SMU vs Clemson starts on October 18, 2025 at 3:30 PM EST.

Venue: Memorial Stadium.

Spread: Clemson -9.5
Moneyline: SMU +272, Clemson -345
Over/Under: 54.5

SMU: (4-2)  |  Clemson: (3-3)

Remi's searched hard and found the best prop for this matchup: K. Jennings over 256.5 Passing Yards.. Prices move—always shop for the best number.

This pairing historically features volatility in the total — Clemson’s mix of tempo and power run schemes contrasts with SMU’s spread speed, so live total swings will be frequent, especially if momentum shifts via turnovers or explosive plays.

SMU trend: SMU has had mixed success covering as an underdog in road ACC games; when their offense is clicking and turnovers are minimal, they’ve hung close, but breakdowns have repeatedly blown games open.

CLEM trend: Clemson often outperforms expectations at home, especially in high-stakes matchups, leveraging crowd noise, coaching stability, and in-state recruiting depth to tilt tight games in its favor.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

SMU vs. Clemson Odds

Remi is pouring through tons of data on each line. In fact, anytime the SMU vs Clemson trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable betting trends.

SMU vs Clemson Opening Odds

SMU Moneyline: +272
CLEM Moneyline: -345
SMU Spread: +9.5
CLEM Spread: -9.5
Over/Under: 54.5

SMU vs Clemson Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-360
 
-9.5 (-105)
O 55 (-118)
U 55 (-107)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-115
-105
-1 (-110)
+1 (-110)
O 51 (-110)
U 51 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-240
+185
-6.5 (-112)
+6.5 (-109)
O 56 (-110)
U 56 (-112)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4500
+1550
-26.5 (-110)
+26.5 (-110)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+160
-205
+4.5 (-110)
-4.5 (-110)
O 50 (-112)
U 50 (-110)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1700
+950
-21.5 (-110)
+21.5 (-110)
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-400
+310
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-305
+240
-7.5 (-105)
+7.5 (-115)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+115
-2.5 (-110)
+2.5 (-110)
O 58.5 (-110)
U 58.5 (-110)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-210
+175
-5 (-110)
+5 (-110)
O 63.5 (-110)
U 63.5 (-110)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1200
-5000
+25.5 (-113)
-25.5 (-108)
O 54.5 (-115)
U 54.5 (-106)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+228
-285
+7 (-110)
-7 (-110)
O 43 (-110)
U 43 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-480
+360
-12.5 (-110)
+12.5 (-110)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-175
+148
-3.5 (-110)
+3.5 (-110)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+600
-1000
+17.5 (-112)
-17.5 (-109)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-600
 
-14.5 (-110)
O 63 (-110)
U 63 (-110)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+180
-220
+5 (-110)
-5 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-155
+3 (-110)
-3 (-110)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
+100
-120
+1 (-110)
-1 (-110)
O 57 (-110)
U 57 (-110)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+285
-365
+9.5 (-110)
-9.5 (-110)
O 48 (-115)
U 48 (-105)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-420
+320
-10.5 (-115)
+10.5 (-105)
O 49 (-110)
U 49 (-110)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-110)
-3 (-110)
O 61.5 (-110)
U 61.5 (-110)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+270
-345
+8.5 (-110)
-8.5 (-110)
O 39 (-110)
U 39 (-110)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-480
+360
-12 (-110)
+12 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+120
-152
+2.5 (-105)
-2.5 (-117)
O 48.5 (-115)
U 48.5 (-106)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-225
+185
-6 (-110)
+6 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+175
-210
+5.5 (-110)
-5.5 (-110)
O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-105
-115
+1 (-110)
-1 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+475
-750
+15.5 (-110)
-15.5 (-110)
O 62.5 (-113)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+162
-195
+4.5 (-110)
-4.5 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-800
 
-16.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-155
+130
-3 (-110)
+3 (-110)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+118
-140
+2.5 (-110)
-2.5 (-110)
O 52.5 (-105)
U 52.5 (-115)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+200
-260
+6.5 (-107)
-6.5 (-114)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+105
 
+1.5 (-110)
 
O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+335
 
+11 (-110)
 
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+2800
-10000
+38.5 (-114)
-38.5 (-107)
O 56.5 (-110)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+162
-195
+4.5 (-110)
-4.5 (-110)
O 67.5 (-110)
U 67.5 (-110)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-267
+215
-7 (-105)
+7 (-115)
O 44.5 (-115)
U 44.5 (-105)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-750
+450
-15.5 (-110)
+15.5 (-110)
O 55.5 (-107)
U 55.5 (-114)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-110)
-33.5 (-110)
O 44.5 (-110)
U 44.5 (-110)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+270
-345
+9.5 (-110)
-9.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30 (-109)
-30 (-112)
O 45.5 (-112)
U 45.5 (-109)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 62.5 (-110)
U 62.5 (-110)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-650
+460
-14.5 (-115)
+14.5 (-105)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-145
+122
-2.5 (-115)
+2.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1350
-3500
+25.5 (-110)
-25.5 (-110)
O 55 (-110)
U 55 (-110)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+185
-225
+5.5 (-110)
-5.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-360
+275
-9.5 (-107)
+9.5 (-114)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+235
-310
+7.5 (-115)
-7.5 (-107)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+400
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers SMU Mustangs vs. Clemson Tigers on October 18, 2025 at Memorial Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN