Purdue vs Northwestern Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 18)

Updated: 2025-10-11T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

Purdue (2-4) travels to Evanston to face Northwestern (4-2) on October 18, with the Wildcats entering as a modest favorite. The line reflects Purdue’s struggles and Northwestern’s recent uptick in consistency, while the total suggests the market expects a moderate offensive output from both sides.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 18, 2025

Start Time: 3:00 PM EST​

Venue: Lanny and Sharon Martin Lakeside Facility​

Wildcats Record: (4-2)

Boilermakers Record: (2-4)

OPENING ODDS

PURDUE Moneyline: +159

NWEST Moneyline: -191

PURDUE Spread: +3.5

NWEST Spread: -3.5

Over/Under: 48.5

PURDUE
Betting Trends

  • Purdue’s ATS record this season is mixed overall, and on the road they’ve struggled to cover, especially in Big Ten games where they are often underdog or challenged in matchups.

NWEST
Betting Trends

  • Northwestern tends to perform well versus the spread at home, particularly in conference play, using their defensive identity and home-field edge to keep games tighter than lines suggest.

MATCHUP TRENDS

  • Purdue’s recent games have featured large swings in scoring from quarter to quarter, making live betting profitable, while Northwestern’s defense has forced turnovers in four of their six games — in tight Big Ten matchups, those takeaways often decide spreads.

PURDUE vs. NWEST
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: R. Browne over 212.5 Passing Yards.

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Purdue vs Northwestern Prediction & Odds:
Free CFB Betting Insights for 10/18/25

The Big Ten West showdown between the Purdue Boilermakers and the Northwestern Wildcats on October 18, 2025, brings together two teams with very different trajectories but similar levels of urgency as the season crosses its midpoint. Purdue enters the matchup searching for consistency under head coach Ryan Walters, whose second year at the helm has been marked by uneven performances and a young roster still learning how to finish close games. Northwestern, on the other hand, has continued its resurgence under David Braun, who has engineered one of the more remarkable program stabilizations in recent conference memory. The Wildcats have leaned heavily on their defense and situational discipline to stay competitive in a division where margins are always razor-thin. This matchup will feature contrasting identities — Purdue’s pass-heavy, explosive-oriented offense against Northwestern’s methodical, defense-first style that thrives on controlling pace and field position. Purdue quarterback Hudson Card has flashed NFL-caliber arm strength and decision-making, but inconsistency in protection and a lack of balance in the running game have often forced him into unfavorable situations. His connection with wideouts like Deion Burks and TJ Sheffield gives the Boilermakers the ability to stretch the field, but turnovers and stalled drives have haunted them throughout the season. Running back Devin Mockobee remains the most reliable weapon, capable of grinding out yards after contact, yet his success depends largely on an offensive line that has struggled to open holes against physical fronts.

On defense, Purdue has shown improvement in spurts, particularly with a front seven that can pressure the quarterback, led by Nic Scourton’s edge presence, but secondary lapses have cost them dearly in key moments. Northwestern’s offense, led by quarterback Brendan Sullivan, has quietly improved thanks to an emphasis on efficiency rather than explosiveness. The Wildcats rely on a steady run game featuring Cam Porter and a quick passing attack that limits mistakes and plays to their defense’s strength. That defense, anchored by linebacker Bryce Gallagher and cornerback Cameron Mitchell, remains the heart of Northwestern’s identity — fundamentally sound, disciplined, and opportunistic. Expect the Wildcats to disguise coverages, bring timely pressure, and force Purdue to sustain long drives without the benefit of chunk plays. For Purdue, success will hinge on protecting Card and finding early offensive rhythm to keep the defense fresh. If Northwestern can force the Boilermakers into obvious passing downs, their pass rush could dictate the game’s tone. Both teams understand the stakes — a win keeps postseason aspirations alive, while a loss could accelerate doubts about offensive direction. This will likely be a gritty, field-position-driven battle where turnovers, third-down conversions, and red-zone execution decide the outcome. Purdue’s big-play potential gives it a puncher’s chance, but Northwestern’s discipline and home-field composure make them the safer bet to emerge from this clash with a crucial conference victory.

Purdue Boilermakers CFB Preview

The Purdue Boilermakers head to Evanston for a pivotal matchup against Northwestern on October 18, 2025, looking to shake off a stretch of uneven performances and reclaim the offensive rhythm that made them dangerous early in the season. Under head coach Ryan Walters, Purdue has shown flashes of improvement, particularly in its ability to move the ball through the air, but costly mistakes, red-zone inefficiency, and an inability to finish drives have kept them from turning potential into consistent success. Quarterback Hudson Card continues to be the centerpiece of the offense, offering a blend of arm talent, mobility, and composure that gives the Boilermakers a fighting chance in any game. Card’s chemistry with wideouts Deion Burks and TJ Sheffield has been a bright spot, as both receivers bring speed and route precision that can stretch defenses horizontally and vertically. However, the offensive line remains a question mark, having allowed too many pressures and struggling to establish consistent push in the running game. Running back Devin Mockobee, known for his burst and contact balance, has been productive when given space, but too often he’s been forced to create on his own behind a line that struggles against physical defensive fronts like Northwestern’s.

For Purdue to win on the road, balance will be key — they’ll need to sustain drives with effective early-down runs while using play action to keep the Wildcats’ linebackers off balance. Defensively, Purdue’s aggressive scheme under Walters will look to create chaos at the line of scrimmage and pressure Northwestern’s quarterback into hurried decisions. Edge rusher Nic Scourton leads the charge with his relentless motor and knack for disrupting timing, while linebacker Yanni Karlaftis anchors the second level with range and pursuit ability. The Boilermakers’ secondary, however, remains their most volatile unit, prone to giving up big plays when forced into man coverage for extended periods. Containing Northwestern’s short passing attack and tackling in space will be essential, as the Wildcats excel at turning modest gains into chain-moving plays. Purdue’s defensive front must also tighten its gap integrity to prevent running back Cam Porter from finding cutback lanes that can extend drives. On special teams, kicker Ben Freehill and punter Jack Ansell provide stability, but Purdue will need to avoid the hidden-yardage battles that Northwestern so often wins with field position. If Card can stay upright, protect the football, and convert key third downs, the Boilermakers have the tools to keep this contest close deep into the second half. However, their path to victory depends on execution and poise — areas that have wavered on the road. This game represents a gut-check moment for Purdue, one that will test their toughness, discipline, and ability to respond to adversity against one of the Big Ten’s most fundamentally sound programs.

Purdue (2-4) travels to Evanston to face Northwestern (4-2) on October 18, with the Wildcats entering as a modest favorite. The line reflects Purdue’s struggles and Northwestern’s recent uptick in consistency, while the total suggests the market expects a moderate offensive output from both sides. Purdue vs Northwestern AI Prediction: Free CFB Betting Insights for Oct 18. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Northwestern Wildcats CFB Preview

The Northwestern Wildcats return to Ryan Field on October 18, 2025, looking to build upon a strong start to their Big Ten campaign and further establish themselves as one of the conference’s most improved programs under head coach David Braun. After exceeding expectations last season, Northwestern has carried that momentum into this year with a disciplined, well-balanced approach that prioritizes efficiency, situational awareness, and physical play on both sides of the ball. The Wildcats have developed a clear identity centered around tough defense and mistake-free offense, and those traits have helped them navigate tight games against more athletic opponents. Quarterback Brendan Sullivan has been steady and efficient, excelling in short-to-intermediate passing where he can utilize timing and accuracy rather than raw arm strength. His ability to manage the offense, make quick reads, and protect the football has been instrumental in Northwestern’s success. Sullivan’s top targets, including wide receiver AJ Henning and tight end Charlie Mangieri, have thrived in the system, consistently finding soft spots in coverage and extending drives. On the ground, running back Cam Porter remains a workhorse, providing dependable production between the tackles and helping control tempo. Behind a veteran offensive line that has improved its protection and run-blocking fundamentals, the Wildcats have been able to win the time-of-possession battle in several key games.

Defensively, Northwestern continues to shine as one of the Big Ten’s most cohesive units. Linebacker Bryce Gallagher anchors the group with his leadership and ability to diagnose plays quickly, while defensive end Sean McLaughlin provides steady pressure off the edge. The Wildcats’ defensive front is built on gap discipline and technique rather than sheer size, but their ability to collapse pockets and limit rushing lanes has made them a formidable challenge. The secondary, led by cornerback Cameron Mitchell and safety Rod Heard II, has been opportunistic, forcing timely turnovers and keeping explosive plays to a minimum. Against a Purdue team that relies heavily on quarterback Hudson Card and wideouts Deion Burks and TJ Sheffield, Northwestern’s defensive game plan will likely emphasize preventing deep shots and forcing the Boilermakers into long, methodical drives where mistakes are more likely. Special teams, often an overlooked strength, could also play a decisive role — the Wildcats have been exceptional in coverage and have a reliable kicking unit that consistently helps with field position. Home-field advantage has been a significant factor for Northwestern this season, as their crowd energy and defensive intensity tend to peak in Evanston. The key to victory will be maintaining offensive rhythm, winning on third downs, and continuing their elite red-zone defense that has frustrated opponents all season. If Northwestern can dictate pace, win the turnover battle, and avoid giving Purdue short fields, the Wildcats have every opportunity to secure another statement victory and strengthen their position as one of the Big Ten West’s most consistent and dangerous teams.

Purdue vs. Northwestern Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the Boilermakers and Wildcats play there’s always several intriguing observations to key in on. Not to mention games played at Lanny and Sharon Martin Lakeside Facility in Oct can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: R. Browne over 212.5 Passing Yards.

Purdue vs. Northwestern Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every facet between the Boilermakers and Wildcats and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.

Interestingly enough, the data has been most keyed in on the linear correlation of emphasis knucklehead sportsbettors regularly put on coaching factors between a Boilermakers team going up against a possibly deflated Wildcats team. We’ve found the true game analytics might reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Purdue vs Northwestern picks, computer picks Boilermakers vs Wildcats, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Boilermakers Betting Trends

Purdue’s ATS record this season is mixed overall, and on the road they’ve struggled to cover, especially in Big Ten games where they are often underdog or challenged in matchups.

Wildcats Betting Trends

Northwestern tends to perform well versus the spread at home, particularly in conference play, using their defensive identity and home-field edge to keep games tighter than lines suggest.

Boilermakers vs. Wildcats Matchup Trends

Purdue’s recent games have featured large swings in scoring from quarter to quarter, making live betting profitable, while Northwestern’s defense has forced turnovers in four of their six games — in tight Big Ten matchups, those takeaways often decide spreads.

Purdue vs. Northwestern Game Info

Purdue vs Northwestern starts on October 18, 2025 at 3:00 PM EST.

Venue: Lanny and Sharon Martin Lakeside Facility.

Spread: Northwestern -3.5
Moneyline: Purdue +159, Northwestern -191
Over/Under: 48.5

Purdue: (2-4)  |  Northwestern: (4-2)

Remi's searched hard and found the best prop for this matchup: R. Browne over 212.5 Passing Yards.. Prices move—always shop for the best number.

Purdue’s recent games have featured large swings in scoring from quarter to quarter, making live betting profitable, while Northwestern’s defense has forced turnovers in four of their six games — in tight Big Ten matchups, those takeaways often decide spreads.

PURDUE trend: Purdue’s ATS record this season is mixed overall, and on the road they’ve struggled to cover, especially in Big Ten games where they are often underdog or challenged in matchups.

NWEST trend: Northwestern tends to perform well versus the spread at home, particularly in conference play, using their defensive identity and home-field edge to keep games tighter than lines suggest.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Purdue vs. Northwestern Odds

Remi is pouring through loads of data on each line. In fact, anytime the Purdue vs Northwestern trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable betting trends.

Purdue vs Northwestern Opening Odds

PURDUE Moneyline: +159
NWEST Moneyline: -191
PURDUE Spread: +3.5
NWEST Spread: -3.5
Over/Under: 48.5

Purdue vs Northwestern Live Odds

Games PTS ML SPR O/U
Nov 11, 2025 7:30PM EST
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Akron Zips
11/11/25 7:30PM
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AKRON
+205
-250
+6.5 (-105)
-6.5 (-115)
O 46.5 (-115)
U 46.5 (-105)
Nov 11, 2025 8:00PM EST
Ohio Bobcats
Western Michigan Broncos
11/11/25 8PM
OHIO
WMICH
-108
-108
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Nov 12, 2025 7:00PM EST
Northern Illinois Huskies
Umass Minutemen
11/12/25 7PM
NILL
UMASS
-480
 
-11.5 (-105)
 
O 43.5 (-105)
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Nov 12, 2025 7:00PM EST
Buffalo Bulls
Central Michigan Chippewas
11/12/25 7PM
BUFF
CMICH
+100
-118
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Nov 12, 2025 7:00PM EST
Toledo Rockets
Miami Ohio Redhawks
11/12/25 7PM
TOLEDO
MIAOH
-176
 
-3.5 (-115)
 
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U 45.5 (-110)
Nov 13, 2025 7:30PM EST
Troy Trojans
Old Dominion Monarchs
11/13/25 7:30PM
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OLDDOM
+350
-450
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-10.5 (-115)
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U 52.5 (-110)
Nov 14, 2025 7:30PM EST
Clemson Tigers
Louisville Cardinals
11/14/25 7:30PM
CLEM
LVILLE
+122
-146
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O 50.5 (-105)
U 50.5 (-115)
Nov 14, 2025 9:00PM EST
Minnesota Golden Gophers
Oregon Ducks
11/14/25 9PM
MINN
OREG
+1600
-4500
+25.5 (-115)
-25.5 (-105)
O 44.5 (-110)
U 44.5 (-110)
Nov 15, 2025 12:00PM EST
Air Force Falcons
UConn Huskies
11/15/25 12PM
AF
UCONN
+235
-295
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O 63.5 (-110)
U 63.5 (-110)
Nov 15, 2025 12:00PM EST
Michigan Wolverines
Northwestern Wildcats
11/15/25 12PM
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NWEST
-600
+430
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+12.5 (-110)
O 41.5 (-105)
U 41.5 (-115)
Nov 15, 2025 12:00PM EST
UTSA Roadrunners
Charlotte 49ers
11/15/25 12PM
UTSA
CHARLO
-1600
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Nov 15, 2025 12:00PM EST
South Florida Bulls
Navy Midshipmen
11/15/25 12PM
SFLA
NAVY
-465
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+10.5 (-110)
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U 64.5 (-105)
Nov 15, 2025 12:00PM EST
Arizona Wildcats
Cincinnati Bearcats
11/15/25 12PM
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CINCY
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U 56.5 (-115)
Nov 15, 2025 12:00PM EST
Eastern Michigan Eagles
Ball State Cardinals
11/15/25 12PM
EMICH
BALLST
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+110
-2.5 (-110)
+2.5 (-110)
O 50.5 (-105)
U 50.5 (-115)
Nov 15, 2025 12:00PM EST
Notre Dame Fighting Irish
Pittsburgh Panthers
11/15/25 12PM
ND
PITT
-465
+350
-11.5 (-110)
+11.5 (-110)
O 55.5 (-108)
U 55.5 (-112)
Nov 15, 2025 12:00PM EST
South Carolina Gamecocks
Texas A&M Aggies
11/15/25 12PM
SC
TEXAM
+860
-1600
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O 47.5 (-115)
U 47.5 (-105)
Nov 15, 2025 12:00PM EST
Wisconsin Badgers
Indiana Hoosiers
11/15/25 12PM
WISC
IND
+3500
-20000
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-29.5 (-110)
O 43.5 (-115)
U 43.5 (-105)
Nov 15, 2025 12:00PM EST
Kansas State Wildcats
Oklahoma State Cowboys
11/15/25 12PM
KSTATE
OKLAST
-2000
+980
-19.5 (-115)
+19.5 (-105)
O 52.5 (-110)
U 52.5 (-110)
Nov 15, 2025 12:45PM EST
Arkansas Razorbacks
LSU Tigers
11/15/25 12:45PM
ARK
LSU
+180
-220
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-5.5 (-115)
O 56.5 (-110)
U 56.5 (-110)
Nov 15, 2025 1:00PM EST
Oregon State Beavers
Tulsa Golden Hurricane
11/15/25 1PM
OREGST
TULSA
-132
+110
-2.5 (-110)
+2.5 (-110)
O 48.5 (-110)
U 48.5 (-110)
Nov 15, 2025 1:00PM EST
West Virginia Mountaineers
Arizona State Sun Devils
11/15/25 1PM
WVU
ARIZST
+385
-520
+11.5 (-110)
-11.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Nov 15, 2025 1:30PM EST
Tennessee Tech Golden Eagles
Kentucky Wildcats
11/15/25 1:30PM
TNTECH
UK
+1200
-3000
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-22.5 (-110)
O 52.5 (-105)
U 52.5 (-115)
Nov 15, 2025 2:00PM EST
Marshall Thundering Herd
Georgia State Panthers
11/15/25 2PM
MARSH
GAST
-300
+240
-7.5 (-105)
+7.5 (-115)
O 63.5 (-110)
U 63.5 (-110)
Nov 15, 2025 2:00PM EST
North Texas Mean Green
UAB Blazers
11/15/25 2PM
NOTEX
UAB
-1250
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U 69.5 (-110)
Nov 15, 2025 3:00PM EST
UTEP Miners
Missouri State Bears
11/15/25 3PM
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MIZZST
+150
-182
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O 48.5 (-110)
U 48.5 (-110)
Nov 15, 2025 3:00PM EST
Colorado State Rams
New Mexico Lobos
11/15/25 3PM
COLOST
NMEX
+490
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U 53.5 (-110)
Nov 15, 2025 3:30PM EST
San Jose State Spartans
Nevada Wolf Pack
11/15/25 3:30PM
SJST
NEVADA
-335
+265
-9.5 (-110)
+9.5 (-110)
O 52.5 (-106)
U 52.5 (-114)
Nov 15, 2025 3:30PM EST
South Alabama Jaguars
UL Monroe Warhawks
11/15/25 3:30PM
SBAMA
MONROE
-205
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Nov 15, 2025 3:30PM EST
UCF Knights
Texas Tech Red Raiders
11/15/25 3:30PM
UCF
TXTECH
+1280
-3500
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-23.5 (-120)
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U 47.5 (-105)
Nov 15, 2025 3:30PM EST
NC State Wolfpack
Miami Hurricanes
11/15/25 3:30PM
NCST
MIAMI
+460
-650
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U 55.5 (-110)
Nov 15, 2025 3:30PM EST
Maryland Terrapins
Illinois Fighting Illini
11/15/25 3:30PM
MD
ILL
+480
-710
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-14.5 (-110)
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U 53.5 (-110)
Nov 15, 2025 3:30PM EST
Georgia Tech Yellow Jackets
Boston College Eagles
11/15/25 3:30PM
GATECH
BC
-900
+590
-16.5 (-115)
+16.5 (-105)
O 58.5 (-110)
U 58.5 (-110)
Nov 15, 2025 3:30PM EST
Penn State Nittany Lions
Michigan State Spartans
11/15/25 3:30PM
PSU
MICHST
-300
+240
-7.5 (-106)
+7.5 (-114)
O 49.5 (-110)
U 49.5 (-110)
Nov 15, 2025 3:30PM EST
MTSU Blue Raiders
Western Kentucky Hilltoppers
11/15/25 3:30PM
MTSU
WKY
 
-610
 
-13.5 (-115)
O 56.5 (-105)
U 56.5 (-115)
Nov 15, 2025 3:30PM EST
Virginia Cavaliers
Duke Blue Devils
11/15/25 3:30PM
UVA
DUKE
+184
-225
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-6.5 (-110)
O 57.5 (-110)
U 57.5 (-110)
Nov 15, 2025 3:30PM EST
Iowa Hawkeyes
USC Trojans
11/15/25 3:30PM
IOWA
USC
+220
-275
+6.5 (-102)
-6.5 (-120)
O 49.5 (-112)
U 49.5 (-108)
Nov 15, 2025 3:30PM EST
App State Mountaineers
James Madison Dukes
11/15/25 3:30PM
APPST
JMAD
 
-1700
 
-21.5 (-102)
O 53.5 (-115)
U 53.5 (-105)
Nov 15, 2025 3:30PM EST
Texas State Bobcats
USM Golden Eagles
11/15/25 3:30PM
TEXST
USM
+188
 
+5.5 (-104)
 
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U 65.5 (-105)
Nov 15, 2025 3:30PM EST
Oklahoma Sooners
Alabama Crimson Tide
11/15/25 3:30PM
OKLA
BAMA
+180
-220
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Nov 15, 2025 4:00PM EST
Florida Atlantic Owls
Tulane Green Wave
11/15/25 4PM
FAU
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+570
-850
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Nov 15, 2025 4:00PM EST
Memphis Tigers
East Carolina Pirates
11/15/25 4PM
MEMP
ECAR
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-142
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Nov 15, 2025 4:15PM EST
New Mexico State Aggies
Tennessee Volunteers
11/15/25 4:15PM
NMEXST
TENN
+8000
-50000
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O 61.5 (-115)
U 61.5 (-105)
Nov 15, 2025 4:30PM EST
North Carolina Tar Heels
Wake Forest Demon Deacons
11/15/25 4:30PM
UNC
WAKE
+188
-230
+6.5 (-115)
-6.5 (-105)
O 39.5 (-110)
U 39.5 (-110)
Nov 15, 2025 5:00PM EST
Liberty Flames
FIU Panthers
11/15/25 5PM
LIB
FIU
-140
 
-2.5 (-120)
 
O 53.5 (-110)
U 53.5 (-110)
Nov 15, 2025 6:00PM EST
Coastal Carolina Chanticleers
Georgia Southern Eagles
11/15/25 6PM
COAST
GASO
+116
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-2.5 (-115)
O 60.5 (-110)
U 60.5 (-110)
Nov 15, 2025 7:00PM EST
Utah State Aggies
UNLV Rebels
11/15/25 7PM
UTAHST
UNLV
+184
-225
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-6.5 (-105)
O 71.5 (-105)
U 71.5 (-115)
Nov 15, 2025 7:00PM EST
Florida Gators
Ole Miss Rebels
11/15/25 7PM
FLA
OLEMISS
+530
-780
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-15.5 (-110)
O 53.5 (-115)
U 53.5 (-105)
Nov 15, 2025 7:00PM EST
Delaware Blue Hens
Sam Houston State Bearkats
11/15/25 7PM
DEL
SAMST
-350
+275
-9.5 (-110)
+9.5 (-110)
O 56.5 (-110)
U 56.5 (-110)
Nov 15, 2025 7:00PM EST
Utah Utes
Baylor Bears
11/15/25 7PM
UTAH
BAYLOR
-330
+260
-8.5 (-110)
+8.5 (-110)
O 60.5 (-108)
U 60.5 (-112)
Nov 15, 2025 7:00PM EST
Purdue Boilermakers
Washington Huskies
11/15/25 7PM
PURDUE
WASH
+660
-1050
+16.5 (-106)
-16.5 (-114)
O 53.5 (-110)
U 53.5 (-110)
Nov 15, 2025 7:30PM EST
Virginia Tech Hokies
Florida State Seminoles
11/15/25 7:30PM
VATECH
FSU
+450
-630
+13.5 (-105)
-13.5 (-115)
O 54.5 (-115)
U 54.5 (-105)
Nov 15, 2025 7:30PM EST
Texas Longhorns
Georgia Bulldogs
11/15/25 7:30PM
TEXAS
UGA
+180
-220
+6.5 (-115)
-6.5 (-105)
O 48.5 (-114)
U 48.5 (-106)
Nov 15, 2025 7:30PM EST
UCLA Bruins
Ohio State Buckeyes
11/15/25 7:30PM
UCLA
OHIOST
+4000
-30000
+33.5 (-110)
-33.5 (-110)
O 48.5 (-110)
U 48.5 (-110)
Nov 15, 2025 7:45PM EST
Mississippi State Bulldogs
Missouri Tigers
11/15/25 7:45PM
MISSST
MIZZOU
+230
-285
+7.5 (-122)
-7.5 (+100)
O 51.5 (-110)
U 51.5 (-110)
Nov 15, 2025 8:00PM EST
Kennesaw State Owls
Jacksonville State Gamecocks
11/15/25 8PM
KENSAW
JAXST
-156
+130
-3.5 (-104)
+3.5 (-118)
O 54.5 (-110)
U 54.5 (-110)
Nov 15, 2025 10:00PM EST
Louisiana Tech Bulldogs
Washington State Cougars
11/15/25 10PM
LATECH
WASHST
+250
-315
+7.5 (-106)
-7.5 (-114)
O 44.5 (-114)
U 44.5 (-106)
Nov 15, 2025 10:15PM EST
TCU Horned Frogs
BYU Cougars
11/15/25 10:15PM
TCU
BYU
+150
-184
+4.5 (-110)
-4.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 15, 2025 10:30PM EST
Boise State Broncos
San Diego State Aztecs
11/15/25 10:30PM
BOISE
SDGST
+115
-138
+2.5 (-104)
-2.5 (-118)
O 41.5 (-104)
U 41.5 (-118)
Nov 15, 2025 10:30PM EST
Wyoming Cowboys
Fresno State Bulldogs
11/15/25 10:30PM
WYO
FRESNO
+140
-170
+3.5 (-112)
-3.5 (-108)
O 40.5 (-110)
U 40.5 (-110)
Dec 6, 2025 8:00PM EST
Ohio State Buckeyes
Indiana Hoosiers
12/6/25 8PM
OHIOST
IND
-225
+180
-5.5 (-122)
+5.5 (+100)
O 49.5 (-110)
U 49.5 (-110)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Purdue Boilermakers vs. Northwestern Wildcats on October 18, 2025 at Lanny and Sharon Martin Lakeside Facility.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
JAXST@UTEP JAXST -105 57.0% 7 WIN
FSU@CLEM CLEM -118 57.1% 5 WIN
UNLV@COLOST UNLV -4 55.2% 5 WIN
OREG@IOWA IOWA +6.5 53.3% 2 WIN
NEB@UCLA NEB +1.5 55.8% 5 WIN
AUBURN@VANDY AUBURN +6.5 56.2% 6 LOSS
KENSAW@NMEXST NMEXST +10 56.5% 6 WIN
STNFRD@UNC STNFRD +7.5 53.8% 3 WIN
DUKE@UCONN UCONN +8.5 57.9% 7 WIN
NEVADA@UTAHST NEVADA +9.5 55.9% 5 LOSS
SAMST@OREGST SAMST +21 57.7% 7 WIN
NEB@UCLA NICO IAMALEAVA UNDER 180.5 PASS YDS 56.6% 6 LOSS
HOU@UCF HOU -112 58.0% 6 WIN
GASTHRN@APPST GASTHRN +180 36.5% 2 WIN
KENTST@BALLST BALLST -2.5 54.5% 4 WIN
WAKE@FSU WAKE +10.5 56.4% 6 LOSS
WYO@SDGST SDGST -10.5 56.7% 7 WIN
OKLA@TENN TENN -130 58.3% 5 LOSS
GATECH@NCST GATECH -5 56.4% 6 LOSS
MIAMI@SMU MIAMI -10 54.3% 4 LOSS
DEL@LIB DEL +3.5 57.6% 7 LOSS
NMEXST@WKY NMEXST +8.5 57.9% 7 LOSS
IND@MD MD +21.5 54.6% 4 LOSS
CINCY@UTAH CINCY +11 57.6% 7 LOSS
OLDDOM@LAMON LAMON +17 58.4% 8 LOSS
VANDY@TEXAS OVER 46.5 53.7% 2 WIN
MICHST@MINN MAKHI FRAZIER UNDER 52.5 RUSH YDS 55.2% 5 WIN
UNC@CUSE UNC +110 50.4% 2 WIN
MRSHL@COASTAL COASTAL +7 53.3% 3 WIN
FIU@MIZZST FIU +3.5 53.9% 3 LOSS
TEXAM@LSU MARCEL REED OVER 0.5 INT 55.5% 5 WIN
RUT@PURDUE RUT +103 54.0% 4 WIN
TOLEDO@WASHST TOLEDO -110 56.1% 6 LOSS
AUBURN@ARK ARK -128 60.5% 8 LOSS
NCST@PITT NCST +6.5 54.9% 4 LOSS
OHIO@EMICH EMICH +12 54.1% 4 WIN
TCU@WVU WVU +16.5 54.6% 4 WIN
COLO@UTAH COLO +14.5 57.7% 7 LOSS
HOU@ARIZST HOU +7.5 57.1% 7 WIN
UVA@UNC UNC +11.5 56.2% 6 WIN
MINN@IOWA MINN +9.5 57.3% 7 LOSS
UCONN@RICE RICE +10.5 57.1% 6 WIN
FAU@NAVY FAU +14.5 56.7% 6 WIN
LAMON@USM LAMON +13.5 56.4% 6 LOSS
BOISE@NEVADA NEVADA +21.5 56.8% 6 WIN
SALA@GAST GAST +6.5 54.3% 4 LOSS
MIZZST@NMEXST MIZZST -108 54.4% 4 WIN
KENSAW@FIU FIU +3 53.7% 3 LOSS
KENTST@TOLEDO KENTST +24.5 56.9% 6 LOSS
OLDDOM@JMAD JMAD -125 57.9% 7 WIN
TXTECH@ARIZST TXTECH -6.5 54.2% 4 LOSS