Purdue vs Northwestern Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 18)

Updated: 2025-10-11T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

Purdue (2-4) travels to Evanston to face Northwestern (4-2) on October 18, with the Wildcats entering as a modest favorite. The line reflects Purdue’s struggles and Northwestern’s recent uptick in consistency, while the total suggests the market expects a moderate offensive output from both sides.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 18, 2025

Start Time: 3:00 PM EST​

Venue: Lanny and Sharon Martin Lakeside Facility​

Wildcats Record: (4-2)

Boilermakers Record: (2-4)

OPENING ODDS

PURDUE Moneyline: +159

NWEST Moneyline: -191

PURDUE Spread: +3.5

NWEST Spread: -3.5

Over/Under: 48.5

PURDUE
Betting Trends

  • Purdue’s ATS record this season is mixed overall, and on the road they’ve struggled to cover, especially in Big Ten games where they are often underdog or challenged in matchups.

NWEST
Betting Trends

  • Northwestern tends to perform well versus the spread at home, particularly in conference play, using their defensive identity and home-field edge to keep games tighter than lines suggest.

MATCHUP TRENDS

  • Purdue’s recent games have featured large swings in scoring from quarter to quarter, making live betting profitable, while Northwestern’s defense has forced turnovers in four of their six games — in tight Big Ten matchups, those takeaways often decide spreads.

PURDUE vs. NWEST
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: R. Browne over 212.5 Passing Yards.

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Purdue vs Northwestern Prediction & Odds:
Free CFB Betting Insights for 10/18/25

The Big Ten West showdown between the Purdue Boilermakers and the Northwestern Wildcats on October 18, 2025, brings together two teams with very different trajectories but similar levels of urgency as the season crosses its midpoint. Purdue enters the matchup searching for consistency under head coach Ryan Walters, whose second year at the helm has been marked by uneven performances and a young roster still learning how to finish close games. Northwestern, on the other hand, has continued its resurgence under David Braun, who has engineered one of the more remarkable program stabilizations in recent conference memory. The Wildcats have leaned heavily on their defense and situational discipline to stay competitive in a division where margins are always razor-thin. This matchup will feature contrasting identities — Purdue’s pass-heavy, explosive-oriented offense against Northwestern’s methodical, defense-first style that thrives on controlling pace and field position. Purdue quarterback Hudson Card has flashed NFL-caliber arm strength and decision-making, but inconsistency in protection and a lack of balance in the running game have often forced him into unfavorable situations. His connection with wideouts like Deion Burks and TJ Sheffield gives the Boilermakers the ability to stretch the field, but turnovers and stalled drives have haunted them throughout the season. Running back Devin Mockobee remains the most reliable weapon, capable of grinding out yards after contact, yet his success depends largely on an offensive line that has struggled to open holes against physical fronts.

On defense, Purdue has shown improvement in spurts, particularly with a front seven that can pressure the quarterback, led by Nic Scourton’s edge presence, but secondary lapses have cost them dearly in key moments. Northwestern’s offense, led by quarterback Brendan Sullivan, has quietly improved thanks to an emphasis on efficiency rather than explosiveness. The Wildcats rely on a steady run game featuring Cam Porter and a quick passing attack that limits mistakes and plays to their defense’s strength. That defense, anchored by linebacker Bryce Gallagher and cornerback Cameron Mitchell, remains the heart of Northwestern’s identity — fundamentally sound, disciplined, and opportunistic. Expect the Wildcats to disguise coverages, bring timely pressure, and force Purdue to sustain long drives without the benefit of chunk plays. For Purdue, success will hinge on protecting Card and finding early offensive rhythm to keep the defense fresh. If Northwestern can force the Boilermakers into obvious passing downs, their pass rush could dictate the game’s tone. Both teams understand the stakes — a win keeps postseason aspirations alive, while a loss could accelerate doubts about offensive direction. This will likely be a gritty, field-position-driven battle where turnovers, third-down conversions, and red-zone execution decide the outcome. Purdue’s big-play potential gives it a puncher’s chance, but Northwestern’s discipline and home-field composure make them the safer bet to emerge from this clash with a crucial conference victory.

Purdue Boilermakers CFB Preview

The Purdue Boilermakers head to Evanston for a pivotal matchup against Northwestern on October 18, 2025, looking to shake off a stretch of uneven performances and reclaim the offensive rhythm that made them dangerous early in the season. Under head coach Ryan Walters, Purdue has shown flashes of improvement, particularly in its ability to move the ball through the air, but costly mistakes, red-zone inefficiency, and an inability to finish drives have kept them from turning potential into consistent success. Quarterback Hudson Card continues to be the centerpiece of the offense, offering a blend of arm talent, mobility, and composure that gives the Boilermakers a fighting chance in any game. Card’s chemistry with wideouts Deion Burks and TJ Sheffield has been a bright spot, as both receivers bring speed and route precision that can stretch defenses horizontally and vertically. However, the offensive line remains a question mark, having allowed too many pressures and struggling to establish consistent push in the running game. Running back Devin Mockobee, known for his burst and contact balance, has been productive when given space, but too often he’s been forced to create on his own behind a line that struggles against physical defensive fronts like Northwestern’s.

For Purdue to win on the road, balance will be key — they’ll need to sustain drives with effective early-down runs while using play action to keep the Wildcats’ linebackers off balance. Defensively, Purdue’s aggressive scheme under Walters will look to create chaos at the line of scrimmage and pressure Northwestern’s quarterback into hurried decisions. Edge rusher Nic Scourton leads the charge with his relentless motor and knack for disrupting timing, while linebacker Yanni Karlaftis anchors the second level with range and pursuit ability. The Boilermakers’ secondary, however, remains their most volatile unit, prone to giving up big plays when forced into man coverage for extended periods. Containing Northwestern’s short passing attack and tackling in space will be essential, as the Wildcats excel at turning modest gains into chain-moving plays. Purdue’s defensive front must also tighten its gap integrity to prevent running back Cam Porter from finding cutback lanes that can extend drives. On special teams, kicker Ben Freehill and punter Jack Ansell provide stability, but Purdue will need to avoid the hidden-yardage battles that Northwestern so often wins with field position. If Card can stay upright, protect the football, and convert key third downs, the Boilermakers have the tools to keep this contest close deep into the second half. However, their path to victory depends on execution and poise — areas that have wavered on the road. This game represents a gut-check moment for Purdue, one that will test their toughness, discipline, and ability to respond to adversity against one of the Big Ten’s most fundamentally sound programs.

Purdue (2-4) travels to Evanston to face Northwestern (4-2) on October 18, with the Wildcats entering as a modest favorite. The line reflects Purdue’s struggles and Northwestern’s recent uptick in consistency, while the total suggests the market expects a moderate offensive output from both sides. Purdue vs Northwestern AI Prediction: Free CFB Betting Insights for Oct 18. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Northwestern Wildcats CFB Preview

The Northwestern Wildcats return to Ryan Field on October 18, 2025, looking to build upon a strong start to their Big Ten campaign and further establish themselves as one of the conference’s most improved programs under head coach David Braun. After exceeding expectations last season, Northwestern has carried that momentum into this year with a disciplined, well-balanced approach that prioritizes efficiency, situational awareness, and physical play on both sides of the ball. The Wildcats have developed a clear identity centered around tough defense and mistake-free offense, and those traits have helped them navigate tight games against more athletic opponents. Quarterback Brendan Sullivan has been steady and efficient, excelling in short-to-intermediate passing where he can utilize timing and accuracy rather than raw arm strength. His ability to manage the offense, make quick reads, and protect the football has been instrumental in Northwestern’s success. Sullivan’s top targets, including wide receiver AJ Henning and tight end Charlie Mangieri, have thrived in the system, consistently finding soft spots in coverage and extending drives. On the ground, running back Cam Porter remains a workhorse, providing dependable production between the tackles and helping control tempo. Behind a veteran offensive line that has improved its protection and run-blocking fundamentals, the Wildcats have been able to win the time-of-possession battle in several key games.

Defensively, Northwestern continues to shine as one of the Big Ten’s most cohesive units. Linebacker Bryce Gallagher anchors the group with his leadership and ability to diagnose plays quickly, while defensive end Sean McLaughlin provides steady pressure off the edge. The Wildcats’ defensive front is built on gap discipline and technique rather than sheer size, but their ability to collapse pockets and limit rushing lanes has made them a formidable challenge. The secondary, led by cornerback Cameron Mitchell and safety Rod Heard II, has been opportunistic, forcing timely turnovers and keeping explosive plays to a minimum. Against a Purdue team that relies heavily on quarterback Hudson Card and wideouts Deion Burks and TJ Sheffield, Northwestern’s defensive game plan will likely emphasize preventing deep shots and forcing the Boilermakers into long, methodical drives where mistakes are more likely. Special teams, often an overlooked strength, could also play a decisive role — the Wildcats have been exceptional in coverage and have a reliable kicking unit that consistently helps with field position. Home-field advantage has been a significant factor for Northwestern this season, as their crowd energy and defensive intensity tend to peak in Evanston. The key to victory will be maintaining offensive rhythm, winning on third downs, and continuing their elite red-zone defense that has frustrated opponents all season. If Northwestern can dictate pace, win the turnover battle, and avoid giving Purdue short fields, the Wildcats have every opportunity to secure another statement victory and strengthen their position as one of the Big Ten West’s most consistent and dangerous teams.

Purdue vs. Northwestern Prop Picks (AI)

AI algorithm Remi is pouring through loads of datapoints on each player. In fact, anytime the Boilermakers and Wildcats play there’s always several intriguing trends to key in on. Not to mention games played at Lanny and Sharon Martin Lakeside Facility in Oct seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: R. Browne over 212.5 Passing Yards.

Purdue vs. Northwestern Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every angle between the Boilermakers and Wildcats and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.

Interestingly enough, the data has been most focused on the growing weight knucklehead sportsbettors tend to put on coaching factors between a Boilermakers team going up against a possibly healthy Wildcats team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Purdue vs Northwestern picks, computer picks Boilermakers vs Wildcats, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Boilermakers Betting Trends

Purdue’s ATS record this season is mixed overall, and on the road they’ve struggled to cover, especially in Big Ten games where they are often underdog or challenged in matchups.

Wildcats Betting Trends

Northwestern tends to perform well versus the spread at home, particularly in conference play, using their defensive identity and home-field edge to keep games tighter than lines suggest.

Boilermakers vs. Wildcats Matchup Trends

Purdue’s recent games have featured large swings in scoring from quarter to quarter, making live betting profitable, while Northwestern’s defense has forced turnovers in four of their six games — in tight Big Ten matchups, those takeaways often decide spreads.

Purdue vs. Northwestern Game Info

Purdue vs Northwestern starts on October 18, 2025 at 3:00 PM EST.

Venue: Lanny and Sharon Martin Lakeside Facility.

Spread: Northwestern -3.5
Moneyline: Purdue +159, Northwestern -191
Over/Under: 48.5

Purdue: (2-4)  |  Northwestern: (4-2)

Remi's searched hard and found the best prop for this matchup: R. Browne over 212.5 Passing Yards.. Prices move—always shop for the best number.

Purdue’s recent games have featured large swings in scoring from quarter to quarter, making live betting profitable, while Northwestern’s defense has forced turnovers in four of their six games — in tight Big Ten matchups, those takeaways often decide spreads.

PURDUE trend: Purdue’s ATS record this season is mixed overall, and on the road they’ve struggled to cover, especially in Big Ten games where they are often underdog or challenged in matchups.

NWEST trend: Northwestern tends to perform well versus the spread at home, particularly in conference play, using their defensive identity and home-field edge to keep games tighter than lines suggest.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Purdue vs. Northwestern Odds

Remi is pouring through tons of data points on each line. In fact, anytime the Purdue vs Northwestern trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable betting trends.

Purdue vs Northwestern Opening Odds

PURDUE Moneyline: +159
NWEST Moneyline: -191
PURDUE Spread: +3.5
NWEST Spread: -3.5
Over/Under: 48.5

Purdue vs Northwestern Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-340
 
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U 55 (-112)
Oct 22, 2025 9:00PM EDT
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New Mexico State Aggies
10/22/25 9PM
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-103
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+1.5 (-113)
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Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
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Oct 24, 2025 7:00PM EDT
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Charlotte 49ers
10/24/25 7PM
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+26.5 (-110)
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Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
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+150
-195
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Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
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NEVADA
-1600
+910
-21.5 (-110)
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Oct 25, 2025 12:00PM EDT
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North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-420
+280
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Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
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-300
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+7.5 (-116)
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Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
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+2.5 (-108)
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Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
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MEMP
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+5 (-112)
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Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
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IND
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Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
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NEB
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-275
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O 43 (-116)
U 43 (-104)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
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EMICH
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U 60 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-165
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U 54 (-114)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+510
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-17.5 (-113)
O 53 (-112)
U 53 (-112)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
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O 63 (-115)
U 63 (-110)
Oct 25, 2025 12:00PM EDT
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Oklahoma Sooners
10/25/25 12PM
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OKLA
+160
-205
+4.5 (-112)
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O 54 (-114)
U 54 (-109)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-150
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-2.5 (-120)
O 57 (-110)
U 57 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
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ARK
+100
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U 57 (-110)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
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-9.5 (-110)
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U 48 (-113)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
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+10.5 (-110)
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U 48.5 (+100)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
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+130
-150
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O 61.5 (-112)
U 61.5 (-108)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+267
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O 39 (-115)
U 39 (-105)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
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O 46.5 (-115)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+120
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Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
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U 54.5 (-110)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
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O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
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Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
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NAVY
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U 62.5 (-110)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+165
-190
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U 54 (-110)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-725
 
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U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-150
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Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+113
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-2.5 (-110)
O 52.5 (-105)
U 52.5 (-115)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+195
-250
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O 56.5 (-114)
U 56.5 (-112)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+105
 
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U 41 (-105)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+334
 
+11 (-110)
 
O 50 (-110)
U 50 (-110)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
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TXTECH
+3000
-10000
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U 56.5 (-115)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+170
-195
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U 67.5 (-110)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
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Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
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Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
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Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
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-8.5 (-112)
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U 48 (-113)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+2000
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U 45 (-105)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
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O 63 (-110)
U 63 (-110)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-615
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U 48 (-110)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-145
+125
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+2.5 (+100)
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U 48 (-105)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1200
-5000
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-25.5 (-113)
O 55.5 (-114)
U 55.5 (-112)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+189
-225
+5.5 (-110)
-5.5 (-110)
O 46 (-117)
U 46 (-103)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-360
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+10 (-114)
O 53.5 (-112)
U 53.5 (-114)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
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U 47.5 (-115)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+360
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-13.5 (-115)
O 50 (-112)
U 50 (-114)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Purdue Boilermakers vs. Northwestern Wildcats on October 18, 2025 at Lanny and Sharon Martin Lakeside Facility.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN