Michigan State vs Indiana Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 18)
Updated: 2025-10-11T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
Michigan State (3-3, 0-3 Big Ten) travels to Bloomington to face Indiana (5-0, 2-0) on October 18 in a high-stakes conference matchup. Indiana enters with momentum and an offense firing behind transfer quarterback Fernando Mendoza, while Michigan State seeks to rebound after a lopsided loss to UCLA.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Oct 18, 2025
Start Time: 3:30 PM EST
Venue: Memorial Stadium
Hoosiers Record: (6-0)
Spartans Record: (3-3)
OPENING ODDS
MICHST Moneyline: +1575
IND Moneyline: -4348
MICHST Spread: +26.5
IND Spread: -26.5
Over/Under: 53.5
MICHST
Betting Trends
- On the road, MSU has had trouble covering Big Ten games this season, especially when their offense is inconsistent or turnovers mount.
IND
Betting Trends
- At home, Indiana has generally exceeded expectations, especially in 2025, with strong offensive performances and roster continuity translating into covers.
MATCHUP TRENDS
- Indiana’s offense has consistently produced over 40 points this season in wins, which tends to push totals upward; in contrast, MSU’s defensive lapses have led to over-movement in previous matchups, making live total movement and alternate lines worth watching.
MICHST vs. IND
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: F. Mendoza over 2.5 Passing Touchdowns.
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Michigan State vs Indiana Prediction & Odds:
Free CFB Betting Insights for 10/18/25
Quarterback Aidan Chiles has all the physical tools to lead the offense, but his accuracy and composure under pressure have been issues in key moments. Running back Makhi Frazier anchors the ground game, and his ability to establish early down success will be critical to keeping the Hoosiers’ defense honest. Michigan State’s offensive line must improve after allowing too many pressures in recent weeks, as Indiana’s defensive front—led by their relentless edge rushers—will look to disrupt Chiles’ timing from the outset. On the other side of the ball, the Spartans’ defense has shown flashes of toughness, particularly against the run, but has been burned by lapses in coverage and poor tackling in space. Their ability to pressure Mendoza without compromising coverage integrity could determine whether they stay competitive late into the game. Expect Indiana to lean on quick tempo and efficient play-calling to wear down Michigan State’s defense, while the Spartans will look to slow the pace, control possession, and force turnovers to swing momentum. This game may not have national implications, but for both programs, it represents a defining moment in their respective rebuilds—Indiana fighting to validate its legitimacy as a rising Big Ten contender, and Michigan State striving to prove it’s not regressing in a conference that punishes inconsistency. If Indiana’s offense maintains its rhythm and the defense continues its opportunistic play, the Hoosiers could take command early. But if Michigan State finds stability and wins the battle in the trenches, this matchup could turn into a hard-fought Big Ten grinder that’s decided late in the fourth quarter.
New week, new opportunity. pic.twitter.com/cVsyzpkngE
— Michigan State Football (@MSU_Football) October 13, 2025
Michigan State Spartans CFB Preview
The Michigan State Spartans enter this Week 8 Big Ten matchup against Indiana looking to rebound and reclaim some identity after a season marked by inconsistency and growing pains under head coach Jonathan Smith. The Spartans have flashed potential on both sides of the ball but have yet to sustain it over four quarters, particularly against disciplined opponents like the Hoosiers. Offensively, sophomore quarterback Aidan Chiles continues to be the centerpiece of Smith’s rebuild. His arm strength and mobility are evident, but decision-making under pressure has been a recurring issue. When he’s in rhythm, Chiles can stretch defenses vertically and make plays off-script, but turnovers and stalled drives have limited Michigan State’s scoring efficiency. Expect offensive coordinator Brian Lindgren to emphasize quick passes, rollouts, and designed runs to help Chiles settle early and mitigate Indiana’s aggressive pass rush. Running back Makhi Frazier remains the tone-setter for the offense, averaging over four yards per carry and serving as a stabilizing force when the passing game stalls. His ability to keep the offense ahead of schedule on early downs could be key in opening up play-action opportunities. The offensive line, however, remains a work in progress, having struggled with pass protection and run consistency against the Big Ten’s more physical fronts. Against Indiana, that unit will need to play its most disciplined game yet, particularly against an opportunistic defense known for its speed and pursuit. Defensively, the Spartans are still developing chemistry but have shown bright spots.
The front seven, led by linemen Alex VanSumeren and Grady Kelly, can be disruptive when they win leverage battles, while linebacker Jordan Hall has shown strong instincts and tackling range. The Spartans’ biggest challenge will be containing Indiana’s dynamic offense, which has proven capable of both explosive downfield strikes and long, methodical drives. Michigan State’s secondary, which has given up too many chunk plays this season, must tighten coverage and communicate effectively against quarterback Fernando Mendoza’s precision passing attack. Look for the Spartans to mix up their coverage shells, use disguised blitzes, and try to create pressure with their front four rather than relying heavily on the blitz, as overcommitting could expose them to big plays. On special teams, kicker Jonathan Kim remains reliable, while punter Ryan Eckley continues to flip field position—a vital advantage for a team that thrives on keeping games close. For Michigan State to stay competitive, they’ll need to limit penalties, win time of possession, and capitalize on red-zone chances. This is a pivotal test for the Spartans, not only in the standings but in showing resilience amid adversity. If Chiles can protect the football, Frazier can find traction on the ground, and the defense can generate a few momentum-shifting stops, Michigan State has the tools to turn this into a tight, physical contest. However, if they fall behind early or struggle with execution, the Hoosiers’ offensive tempo could make it another long afternoon in Bloomington.

Credit: USA TODAY/IMAGN
Indiana Hoosiers CFB Preview
The Indiana Hoosiers return to Memorial Stadium on October 18, 2025, riding a wave of confidence and stability that has defined Curt Cignetti’s second season at the helm. Under Cignetti’s direction, Indiana has transitioned from a rebuilding program into a legitimate Big Ten contender, and this matchup against Michigan State provides another opportunity to reinforce their progress. Quarterback Fernando Mendoza has been the heart of the Hoosiers’ offensive surge, combining accuracy, composure, and leadership in a system that perfectly suits his strengths. Completing over 70 percent of his passes with a strong touchdown-to-interception ratio, Mendoza has turned Indiana’s passing game into one of the most efficient in the conference. His ability to spread the ball across multiple targets—most notably wide receiver Elijah Sarratt, whose blend of size and route precision has made him a matchup nightmare—has elevated the entire unit. Running back Roman Hemby brings balance and toughness to the offense, thriving in zone-run concepts and providing a reliable safety valve in the passing game. Behind an offensive line that ranks among the Big Ten’s best in pass protection and adjusted line yards, Indiana’s attack thrives on rhythm and versatility, capable of both grinding out drives and hitting explosive plays. The Hoosiers’ offensive play-calling has been calculated yet aggressive, often using tempo and pre-snap motion to exploit mismatches and wear down defenses—a formula that should challenge Michigan State’s young secondary and inconsistent front seven. Defensively, Indiana has taken on Cignetti’s disciplined, opportunistic identity.
The front line, anchored by disruptive edge rusher Lanell Carr and interior stalwart Andre Carter, has been relentless in generating pressure and collapsing pockets, while the linebackers—led by Aaron Casey—have excelled in tackling and coverage responsibilities. The secondary, featuring playmakers such as cornerback Jamier Johnson and safety Phillip Dunnam, has been particularly sharp in zone concepts, limiting explosive plays and capitalizing on turnovers. Expect defensive coordinator Bryant Haines to dial up creative looks designed to confuse Michigan State quarterback Aidan Chiles, mixing zone pressures with delayed blitzes to test his composure. Indiana’s special teams also remain a quiet strength; kicker Chris Freeman has been dependable from distance, and the return units provide field-position advantages that often swing momentum. More importantly, Indiana’s home-field environment has become a genuine asset, with a confident crowd energizing a team that feeds off tempo and early momentum. The key for the Hoosiers will be maintaining composure and execution—avoiding penalties, finishing red-zone trips with touchdowns, and staying ahead of the chains. If Mendoza continues to orchestrate the offense with precision and the defense maintains its disruptive presence, Indiana has every reason to believe they can dictate tempo and pull away late. This team has grown into one that plays complementary football—offense, defense, and special teams working seamlessly—and that cohesion could prove decisive as the Hoosiers look to continue their rise in the Big Ten and secure another crucial conference victory at home.
13 tackles, 1.5 sacks & 1.5 TFLs. @theaidenfisher is your B1G Defensive Player of the Week. pic.twitter.com/SZdPLQZ499
— Indiana Football (@IndianaFootball) October 13, 2025
Michigan State vs. Indiana Prop Picks (AI)
Michigan State vs. Indiana Prediction (AI)

Remi, our AI sports wizard, has been pouring over millions of data from every angle between the Spartans and Hoosiers and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.
The Algorithm has been most watching on the linear correlation of emphasis knucklehead sportsbettors regularly put on player performance factors between a Spartans team going up against a possibly rested Hoosiers team. Trends look to say the true game analytics might reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Michigan State vs Indiana picks, computer picks Spartans vs Hoosiers, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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CFB | 10/21 | KENSAW@FIU | UNLOCK THIS PICK | 3 |
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CFB | 10/21 | WKY@LATECH | UNLOCK THIS PICK | 2 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Spartans Betting Trends
On the road, MSU has had trouble covering Big Ten games this season, especially when their offense is inconsistent or turnovers mount.
Hoosiers Betting Trends
At home, Indiana has generally exceeded expectations, especially in 2025, with strong offensive performances and roster continuity translating into covers.
Spartans vs. Hoosiers Matchup Trends
Indiana’s offense has consistently produced over 40 points this season in wins, which tends to push totals upward; in contrast, MSU’s defensive lapses have led to over-movement in previous matchups, making live total movement and alternate lines worth watching.
Michigan State vs. Indiana Game Info
What time does Michigan State vs Indiana start on October 18, 2025?
Michigan State vs Indiana starts on October 18, 2025 at 3:30 PM EST.
Where is Michigan State vs Indiana being played?
Venue: Memorial Stadium.
What are the opening odds for Michigan State vs Indiana?
Spread: Indiana -26.5
Moneyline: Michigan State +1575, Indiana -4348
Over/Under: 53.5
What are the records for Michigan State vs Indiana?
Michigan State: (3-3) | Indiana: (6-0)
What is the AI best bet for Michigan State vs Indiana?
Remi's searched hard and found the best prop for this matchup: F. Mendoza over 2.5 Passing Touchdowns.. Prices move—always shop for the best number.
What are Michigan State vs Indiana trending bets?
Indiana’s offense has consistently produced over 40 points this season in wins, which tends to push totals upward; in contrast, MSU’s defensive lapses have led to over-movement in previous matchups, making live total movement and alternate lines worth watching.
What are Michigan State trending bets?
MICHST trend: On the road, MSU has had trouble covering Big Ten games this season, especially when their offense is inconsistent or turnovers mount.
What are Indiana trending bets?
IND trend: At home, Indiana has generally exceeded expectations, especially in 2025, with strong offensive performances and roster continuity translating into covers.
Where can I find AI Picks for Michigan State vs Indiana?
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
Michigan State vs. Indiana Odds
AI algorithm Remi is pouring through loads of data points on each player. In fact, anytime the Michigan State vs Indiana trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance rarely follow normal, predictable patterns.
Michigan State vs Indiana Opening Odds
MICHST Moneyline:
+1575 IND Moneyline: -4348
MICHST Spread: +26.5
IND Spread: -26.5
Over/Under: 53.5
Michigan State vs Indiana Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
|
–
–
|
-340
|
-8.5 (-112)
|
O 55 (-108)
U 55 (-112)
|
|
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
|
–
–
|
-122
-103
|
-1.5 (-110)
+1.5 (-113)
|
O 51.5 (-109)
U 51.5 (-114)
|
|
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
|
–
–
|
-240
+188
|
-6.5 (-109)
+6.5 (-113)
|
O 56.5 (-109)
U 56.5 (-114)
|
|
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
|
–
–
|
-4300
+1480
|
-26.5 (-110)
+26.5 (-110)
|
O 61.5 (-103)
U 61.5 (-117)
|
|
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
|
–
–
|
+150
-195
|
+4.5 (-110)
-4.5 (-113)
|
O 49.5 (-113)
U 49.5 (-110)
|
|
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
|
–
–
|
-1600
+910
|
-21.5 (-110)
+21.5 (-110)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
|
–
–
|
-420
+280
|
-10.5 (-107)
+10.5 (-117)
|
O 51.5 (-113)
U 51.5 (-110)
|
|
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
|
–
–
|
-300
+245
|
-7.5 (-104)
+7.5 (-116)
|
O 47.5 (-120)
U 47.5 (+100)
|
|
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
|
–
–
|
-143
+110
|
-2.5 (-115)
+2.5 (-108)
|
O 58.5 (-110)
U 58.5 (-115)
|
|
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
|
–
–
|
-195
+148
|
-5 (-112)
+5 (-112)
|
O 63.5 (-110)
U 63.5 (-115)
|
|
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
|
–
–
|
+1256
-3000
|
+25 (-115)
-25 (-105)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
|
–
–
|
+226
-275
|
+7 (-108)
-7 (-112)
|
O 43 (-116)
U 43 (-104)
|
|
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
|
–
–
|
-470
+364
|
-12.5 (-105)
+12.5 (-115)
|
O 60 (-110)
U 60 (-110)
|
|
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
|
–
–
|
-165
+130
|
-3.5 (-110)
+3.5 (-113)
|
O 54 (-112)
U 54 (-114)
|
|
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
|
–
–
|
+510
-835
|
+17.5 (-112)
-17.5 (-113)
|
O 53 (-112)
U 53 (-112)
|
|
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
|
–
–
|
-590
|
-14 (-114)
|
O 63 (-115)
U 63 (-110)
|
|
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
|
–
–
|
+160
-205
|
+4.5 (-112)
-4.5 (-112)
|
O 54 (-114)
U 54 (-109)
|
|
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
|
–
–
|
+130
-150
|
+2.5 (+100)
-2.5 (-120)
|
O 57 (-110)
U 57 (-110)
|
|
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
|
–
–
|
+100
-120
|
+1 (-110)
-1 (-110)
|
O 57 (-110)
U 57 (-110)
|
|
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
|
–
–
|
+289
-360
|
+9.5 (-110)
-9.5 (-110)
|
O 48 (-107)
U 48 (-113)
|
|
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
|
–
–
|
-400
+316
|
-10.5 (-110)
+10.5 (-110)
|
O 48.5 (-120)
U 48.5 (+100)
|
|
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
|
–
–
|
+130
-150
|
+3 (-110)
-3 (-110)
|
O 61.5 (-112)
U 61.5 (-108)
|
|
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
|
–
–
|
+267
-330
|
+9 (-115)
-9 (-105)
|
O 39 (-115)
U 39 (-105)
|
|
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
|
–
–
|
-530
+370
|
-13 (-109)
+13 (-113)
|
O 46.5 (-115)
U 46.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
|
–
–
|
+120
-148
|
+2.5 (-107)
-2.5 (-118)
|
O 48.5 (-110)
U 48.5 (-113)
|
|
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
|
–
–
|
-225
+189
|
-6 (-110)
+6 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
|
–
–
|
+177
-205
|
+5.5 (-110)
-5.5 (-110)
|
O 41 (-110)
U 41 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
|
–
–
|
-105
-115
|
+1 (-110)
-1 (-110)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
|
–
–
|
+488
-670
|
+14.5 (+100)
-14.5 (-120)
|
O 62.5 (-110)
U 62.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
|
–
–
|
+165
-190
|
+4.5 (-112)
-4.5 (-108)
|
O 54 (-110)
U 54 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
|
–
–
|
-725
|
-16.5 (-107)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
|
–
–
|
-150
+130
|
-3 (-108)
+3 (-112)
|
O 48 (-107)
U 48 (-113)
|
|
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
|
–
–
|
+113
-133
|
+2.5 (-110)
-2.5 (-110)
|
O 52.5 (-105)
U 52.5 (-115)
|
|
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
|
–
–
|
+195
-250
|
+6.5 (-109)
-6.5 (-114)
|
O 56.5 (-114)
U 56.5 (-112)
|
|
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
|
–
–
|
+105
|
+1.5 (-110)
|
O 41 (-115)
U 41 (-105)
|
|
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
|
–
–
|
+334
|
+11 (-110)
|
O 50 (-110)
U 50 (-110)
|
|
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
|
–
–
|
+3000
-10000
|
+38.5 (-115)
-38.5 (-105)
|
O 56.5 (-105)
U 56.5 (-115)
|
|
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
|
–
–
|
+170
-195
|
+4.5 (-111)
-4.5 (-109)
|
O 67.5 (-110)
U 67.5 (-110)
|
|
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
|
–
–
|
-260
+215
|
-7 (-107)
+7 (-113)
|
O 44.5 (-120)
U 44.5 (+100)
|
|
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
|
–
–
|
-715
+430
|
-15.5 (-110)
+15.5 (-113)
|
O 55.5 (-113)
U 55.5 (-113)
|
|
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
|
–
–
|
|
+33 (-110)
-33 (-110)
|
O 44.5 (-108)
U 44.5 (-112)
|
|
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
|
–
–
|
+250
-335
|
+8.5 (-112)
-8.5 (-112)
|
O 48 (-113)
U 48 (-113)
|
|
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
|
–
–
|
+2000
-10000
|
+30 (-107)
-30 (-113)
|
O 45 (-115)
U 45 (-105)
|
|
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
|
–
–
|
+100
-120
|
+1.5 (-113)
-1.5 (-107)
|
O 63 (-110)
U 63 (-110)
|
|
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
|
–
–
|
-615
+455
|
-14.5 (-105)
+14.5 (-115)
|
O 48 (-110)
U 48 (-110)
|
|
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
|
–
–
|
-145
+125
|
-2.5 (-120)
+2.5 (+100)
|
O 48 (-115)
U 48 (-105)
|
|
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
|
–
–
|
+1200
-5000
|
+25.5 (-110)
-25.5 (-113)
|
O 55.5 (-114)
U 55.5 (-112)
|
|
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
|
–
–
|
+189
-225
|
+5.5 (-110)
-5.5 (-110)
|
O 46 (-117)
U 46 (-103)
|
|
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
|
–
–
|
-360
+270
|
-10 (-109)
+10 (-114)
|
O 53.5 (-112)
U 53.5 (-114)
|
|
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
|
–
–
|
+205
-278
|
+7.5 (-115)
-7.5 (-109)
|
O 47.5 (-110)
U 47.5 (-115)
|
|
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
|
–
–
|
+360
-500
|
+13.5 (-108)
-13.5 (-115)
|
O 50 (-112)
U 50 (-114)
|
|
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
|
–
–
|
-275
+220
|
-7.5 (-104)
+7.5 (-118)
|
O 60.5 (-112)
U 60.5 (-108)
|
|
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
|
–
–
|
-200
+164
|
-5.5 (-110)
+5.5 (-110)
|
O 52.5 (-112)
U 52.5 (-108)
|
|
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
|
–
–
|
+660
-1050
|
+17.5 (-115)
-17.5 (-105)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
|
–
–
|
-430
+330
|
-10.5 (-110)
+10.5 (-110)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
|
–
–
|
-105
-114
|
+1.5 (-114)
-1.5 (-106)
|
O 53.5 (-112)
U 53.5 (-108)
|
|
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
|
–
–
|
+150
-182
|
+3.5 (-106)
-3.5 (-114)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
|
–
–
|
-300
+240
|
-7.5 (-110)
+7.5 (-110)
|
O 50.5 (-112)
U 50.5 (-108)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Michigan State Spartans vs. Indiana Hoosiers on October 18, 2025 at Memorial Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
FSU@STNFRD | STNFRD +18 | 56.6% | 6 | WIN |
WASHST@UVA | WASHST +17.5 | 58.8% | 8 | WIN |
NEVADA@NMEX | NEVADA +13.5 | 57.8% | 7 | WIN |
TEXAS@UK | ARCH MANNING UNDER 1.5 PASS TD | 56.1% | 6 | WIN |
ARMY@TULANE | ARMY +10 | 55.3% | 5 | WIN |
SJST@UTAHST | SJST +4 | 54.4% | 4 | LOSS |
LVILLE@MIAMI | LVILLE +12.5 | 56.5% | 6 | WIN |
LVILLE@MIAMI | CJ DANIELS UNDER 4.5 RECEPTIONS | 54.4 | 4 | LOSS |
DEL@JAXST | DEL -2.5 | 57.6% | 6 | LOSS |
UTEP@SAMST | UTEP -2.5 | 53.9% | 3 | WIN |
FIU@WKY | FIU +10.5 | 54.6% | 4 | WIN |
ARKST@SALA | ARKST +7.5 | 54.5% | 4 | WIN |
ARKST@SALA | JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP | 53.3% | 3 | WIN |
SJST@WYO | SJST -120 | 59.8% | 7 | LOSS |
UMASS@KENTST | KENTST -135 | 60.2% | 6 | WIN |
NOILL@EMICH | EMICH +2.5 | 53.9% | 3 | WIN |
BYU@ARIZ | ARIZ +2.5 | 54.2% | 3 | LOSS |
OKLA@TEXAS | OKLA +2.5 | 54.7% | 4 | LOSS |
NMEX@BOISE | NMEX +16.5 | 56.4% | 6 | WIN |
WAKE@OREGST | WAKE -2.5 | 56.7% | 6 | WIN |
ULMON@COASTAL | ULMON -2.5 | 56.8% | 6 | LOSS |
IOWA@WISC | WISC +4 | 54.8% | 4 | LOSS |
TOLEDO@BGREEN | TOLEDO -10 | 56.3% | 6 | LOSS |
SFLA@NOTEX | SFLA +2.5 | 54.3% | 4 | WIN |
FRESNO@COLOST | RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 | 54.4% | 4 | LOSS |
JAXST@SAMST | SAMST +7.5 | 55.3% | 5 | WIN |
USM@GAS | GAS +3.5 | 57.4% | 7 | WIN |
LIB@UTEP | UTEP +2 | 54.5% | 4 | LOSS |
SALA@TROY | SALA -118 | 55.2% | 4 | LOSS |
TULSA@MEMP | MEMP -20.5 | 53.8% | 3 | WIN |
JMAD@GAST | GAST +20.5 | 54.6% | 4 | WIN |
WAKE@VATECH | VATECH -5.5 | 56.6% | 6 | LOSS |
UNLV@WYO | WYO +4.5 | 55.5% | 5 | LOSS |
PSU@UCLA | PSU -24.5 | 56.3% | 6 | LOSS |
TXSTSM@ARKST | TXSTSM -13 | 56.7% | 6 | LOSS |
UVA@LVILLE | ISAAC BROWN OVER 70.5 RUSH YDS | 56.6% | 6 | LOSS |
WVU@BYU | WVU +20.5 | 54.7% | 4 | WIN |
SAMST@NMEXST | SAMST -1.5 | 54.1% | 3 | LOSS |
EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
UK@SC | SC -5.5 | 54.8% | 4 | WIN |
WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |