Louisville vs Miami Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 17)

Updated: 2025-10-10T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

Louisville (4-1) heads into their October 17 road trip to face Miami (5-0) in a marquee ACC matchup, with the Hurricanes entering as dominant favorites and widely expected to test Louisville’s defensive resolve.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 17, 2025

Start Time: 7:00 PM EST​

Venue: Hard Rock Stadium​

Hurricanes Record: (5-0)

Cardinals Record: (4-1)

OPENING ODDS

LVILLE Moneyline: +405

MIAMI Moneyline: -549

LVILLE Spread: +13.5

MIAMI Spread: -13.5

Over/Under: 53.5

LVILLE
Betting Trends

  • Louisville has struggled to consistently cover on the road this season, particularly in ACC games.

MIAMI
Betting Trends

  • Miami has been a strong home bet so far in 2025, frequently beating the spread at home given their dominance across both sides of the ball.

MATCHUP TRENDS

  • Miami is currently favored by about 14.5 points in this matchup, and the over/under is set near 53.5 — suggesting oddsmakers believe this could be a high-scoring affair if Louisville can keep pace with the Hurricanes.

LVILLE vs. MIAMI
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: C. Lacy over 46.5 Receiving Yards.

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Louisville vs Miami Prediction & Odds:
Free CFB Betting Insights for 10/17/25

The Week 8 clash between the Louisville Cardinals and the Miami Hurricanes on October 17, 2025, stands as one of the defining matchups of the ACC schedule and could have serious conference title implications as both teams battle for positioning in what has been an unpredictable season. Miami enters undefeated and brimming with confidence under head coach Mario Cristobal, boasting one of the most balanced rosters in college football. The Hurricanes’ offense, powered by quarterback Cam Ward, has been methodical and explosive, averaging over 36 points per game with a near-elite red-zone touchdown rate. Ward’s command of the offense has allowed Miami to control tempo, dictate field position, and exploit mismatches through the air. His connection with slot receiver Xavier Restrepo and freshman standout Jeremiah Smith has elevated Miami’s passing attack, while running back Mark Fletcher Jr. continues to churn out tough yardage, adding a physical dimension that complements Ward’s precision. Miami’s offensive line has been among the most efficient in pass protection, ranking in the top 10 nationally in adjusted sack rate, a critical advantage against Louisville’s blitz-heavy approach. Defensively, the Hurricanes have been ferocious, anchored by defensive end Rueben Bain Jr., who has developed into one of the ACC’s premier edge rushers. Miami’s front seven leads the league in pressures and ranks top five nationally in yards allowed per play, making life miserable for opposing quarterbacks. The secondary, led by cornerback Daryl Porter Jr., has thrived on tight coverage and disciplined positioning, giving Miami the ability to play aggressively up front.

Louisville, on the other hand, enters with a strong 4-1 record but faces its toughest test yet. Quarterback Tyler Shough has provided veteran stability and poise, completing over 65 percent of his throws while managing the offense efficiently. His rapport with wide receiver Jamari Thrash remains the centerpiece of the Cardinals’ passing game, and the duo’s ability to connect on deep routes will be vital against Miami’s aggressive corners. Running back Isaac Guerendo has added balance to the attack, providing speed and elusiveness that can stretch the edges of Miami’s defense. However, Louisville’s offensive line has shown cracks under pressure, particularly in road environments, and the challenge of neutralizing Bain and Leonard Taylor III could prove decisive. Defensively, the Cardinals rely heavily on linebacker TJ Quinn and a secondary that bends but rarely breaks, yet their vulnerability to big plays through the air remains a concern. Miami’s ability to create explosives, both off play-action and perimeter motion, could expose Louisville’s back-end discipline. The Cardinals will need to generate turnovers and win the field position battle to keep the game within reach, something easier said than done against a disciplined Miami team that ranks top 15 nationally in turnover margin. In the end, this matchup may come down to which quarterback handles pressure better and which defense forces more third-and-long situations. Miami’s superior line play, defensive depth, and home-field edge give them the upper hand, but Louisville’s offensive versatility and knack for timely scoring make them dangerous if the Hurricanes lose focus or struggle early.

Louisville Cardinals CFB Preview

The Louisville Cardinals enter their Week 8 showdown against the Miami Hurricanes on October 17, 2025, as a confident but battle-tested team, looking to prove they belong in the conversation among the ACC’s elite. Head coach Jeff Brohm has steadily built a balanced, explosive offense around quarterback Tyler Shough, who has emerged as a poised veteran leader capable of dissecting defenses both through the air and on the ground. Shough’s 2025 campaign has been defined by efficiency—he’s completing over 65 percent of his passes and maintaining one of the lowest turnover rates in the conference. His chemistry with wide receiver Jamari Thrash remains the foundation of Louisville’s passing game, as the duo continues to produce chunk plays downfield, particularly on vertical routes and play-action concepts designed to exploit aggressive defensive fronts. Tight end Nate Kurisky has also become a valuable safety valve on third downs, while running back Isaac Guerendo has developed into one of the more underrated dual-threat weapons in the ACC. Guerendo’s ability to run between the tackles and contribute in the passing game allows Louisville to stay versatile and unpredictable, forcing defenses to play honestly. However, facing Miami’s top-tier defensive front will be the Cardinals’ most daunting challenge of the season. Miami ranks near the top nationally in pressure rate and run-stop win rate, anchored by Rueben Bain Jr. and Leonard Taylor III, whose disruptive presence could force Shough into uncomfortable situations if Louisville’s offensive line doesn’t hold firm.

The key for Louisville will be to use quick-hitting plays, pre-snap motion, and tempo to prevent Miami from dictating the pace at the line of scrimmage. Brohm’s game-planning often thrives on scripted drives and misdirection, so early success on offense could determine whether the Cardinals can keep the game within reach. Defensively, Louisville’s unit has shown flashes of brilliance but remains inconsistent against high-octane offenses. Linebacker TJ Quinn continues to lead by example, racking up tackles and keeping the front seven organized, while safety M.J. Griffin anchors the back end with physicality and experience. The Cardinals’ defensive success depends heavily on generating turnovers and limiting explosive plays—two areas that have defined their better performances this season. Against Miami, that means forcing Cam Ward into long third downs and collapsing pockets quickly to limit his scrambling opportunities. Louisville will also need to control time of possession, something they’ve done effectively in recent weeks by sustaining long, methodical drives that wear down opposing defenses. If they can establish Guerendo early and use Shough’s mobility to extend plays, they stand a chance to keep Miami’s offense off the field and frustrate the Hurricanes’ rhythm. Still, Hard Rock Stadium has been a fortress for Miami this season, and crowd noise could play a factor in communication for Louisville’s offensive line. For Brohm’s squad, the formula for an upset is simple but difficult—protect the football, avoid third-and-long situations, and capitalize on any defensive lapses. If the Cardinals execute with discipline and creativity, they have the firepower to turn this primetime matchup into a four-quarter fight.

Louisville (4-1) heads into their October 17 road trip to face Miami (5-0) in a marquee ACC matchup, with the Hurricanes entering as dominant favorites and widely expected to test Louisville’s defensive resolve. Louisville vs Miami AI Prediction: Free CFB Betting Insights for Oct 17. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Miami Hurricanes CFB Preview

The Miami Hurricanes return home to Hard Rock Stadium on October 17, 2025, with momentum on their side and the confidence of a team that believes it can make a legitimate run at an ACC title and a potential College Football Playoff berth. Under head coach Mario Cristobal, the Hurricanes have evolved into one of the most complete teams in the country, combining an explosive, balanced offense with a suffocating defense that thrives on physicality and depth. Quarterback Cam Ward has been the driving force behind Miami’s offensive resurgence, bringing precision, poise, and creativity to an attack that averages well over 35 points per game. Ward’s ability to process defenses quickly and make off-platform throws has made him one of the most dangerous signal-callers in the nation. He’s been particularly effective when using tempo and pre-snap motion to manipulate defensive looks, and his rapport with slot receiver Xavier Restrepo and freshman phenom Jeremiah Smith has given Miami a lethal one-two punch in the passing game. Running back Mark Fletcher Jr. provides balance with his downhill running style, keeping defenses honest and wearing down front sevens as games progress. Behind one of the nation’s best offensive lines, the Hurricanes have been dominant in both protection and run blocking, ranking among the top ten in adjusted line yards and fewest sacks allowed. That protection will be crucial against a Louisville defense known for blitzing from multiple angles and trying to confuse quarterbacks with disguised coverages. Defensively, Miami continues to set the tone through relentless pressure and disciplined coverage.

Rueben Bain Jr. headlines a defensive line that has terrorized opposing quarterbacks, while Leonard Taylor III provides interior disruption that collapses pockets and forces hurried decisions. Linebacker Francisco Mauigoa has emerged as a tackling machine, often cleaning up plays at the second level and eliminating yards after contact. In the secondary, cornerback Daryl Porter Jr. and safety Kamren Kinchens provide veteran leadership and instincts, combining for several key takeaways through the early part of the season. Miami’s defense thrives on forcing negative plays—sacks, tackles for loss, and turnovers—which has made them one of the most efficient units in the ACC. Against Louisville, maintaining gap discipline will be essential to containing dual-threat quarterback Tyler Shough and running back Isaac Guerendo, both of whom can extend drives if the defense overcommits. The Hurricanes will likely employ a mix of zone blitzes and spy packages to limit Shough’s mobility while forcing him to beat them with tight-window throws. On special teams, kicker Andy Borregales has been reliable from long range, while the return units remain among the conference’s most dangerous. With Hard Rock Stadium expected to be electric for this prime-time showdown, Miami has every reason to believe they can control the tempo, force turnovers, and make a statement to the rest of the ACC. If Ward and the offense maintain their rhythm and the defense continues its disruptive dominance, the Hurricanes could not only secure another critical conference win but also solidify their place among the nation’s elite.

Louisville vs. Miami Prop Picks (AI)

Remi is pouring through loads of data on each team. In fact, anytime the Cardinals and Hurricanes play there’s always several intriguing trends to key in on. Not to mention games played at Hard Rock Stadium in Oct can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: C. Lacy over 46.5 Receiving Yards.

Louisville vs. Miami Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every past game between the Cardinals and Hurricanes and using recursive machine learning and kick-ass AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most fixated on the growing weight emotional bettors often put on player performance factors between a Cardinals team going up against a possibly improved Hurricanes team. We’ve found the true game analytics appear to reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Louisville vs Miami picks, computer picks Cardinals vs Hurricanes, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Cardinals Betting Trends

Louisville has struggled to consistently cover on the road this season, particularly in ACC games.

Hurricanes Betting Trends

Miami has been a strong home bet so far in 2025, frequently beating the spread at home given their dominance across both sides of the ball.

Cardinals vs. Hurricanes Matchup Trends

Miami is currently favored by about 14.5 points in this matchup, and the over/under is set near 53.5 — suggesting oddsmakers believe this could be a high-scoring affair if Louisville can keep pace with the Hurricanes.

Louisville vs. Miami Game Info

Louisville vs Miami starts on October 17, 2025 at 7:00 PM EST.

Venue: Hard Rock Stadium.

Spread: Miami -13.5
Moneyline: Louisville +405, Miami -549
Over/Under: 53.5

Louisville: (4-1)  |  Miami: (5-0)

Remi's searched hard and found the best prop for this matchup: C. Lacy over 46.5 Receiving Yards.. Prices move—always shop for the best number.

Miami is currently favored by about 14.5 points in this matchup, and the over/under is set near 53.5 — suggesting oddsmakers believe this could be a high-scoring affair if Louisville can keep pace with the Hurricanes.

LVILLE trend: Louisville has struggled to consistently cover on the road this season, particularly in ACC games.

MIAMI trend: Miami has been a strong home bet so far in 2025, frequently beating the spread at home given their dominance across both sides of the ball.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Louisville vs. Miami Odds

AI algorithm Remi is pouring through mountains of data on each player. In fact, anytime the Louisville vs Miami trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments can often follow normal, predictable patterns.

Louisville vs Miami Opening Odds

LVILLE Moneyline: +405
MIAMI Moneyline: -549
LVILLE Spread: +13.5
MIAMI Spread: -13.5
Over/Under: 53.5

Louisville vs Miami Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-370
 
-9.5 (-110)
O 55.5 (-110)
U 55.5 (-110)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-108
-108
-1.5 (-105)
+1.5 (-115)
O 51.5 (-110)
U 51.5 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-225
+185
-6.5 (-110)
+6.5 (-110)
O 55.5 (-112)
U 55.5 (-108)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4000
+1600
-26.5 (-112)
+26.5 (-108)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+164
-198
+4.5 (-108)
-4.5 (-112)
O 49.5 (-115)
U 49.5 (-105)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1800
+1000
-21 (-115)
+21 (-105)
O 50.5 (-112)
U 50.5 (-108)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-395
+310
-10.5 (-108)
+10.5 (-112)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-290
+235
-7.5 (-105)
+7.5 (-115)
O 48.5 (-108)
U 48.5 (-112)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+114
-2.5 (-115)
+2.5 (-105)
O 58.5 (-112)
U 58.5 (-108)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-205
+170
-4.5 (-112)
+4.5 (-108)
O 63.5 (-108)
U 63.5 (-112)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1400
-3200
+25.5 (-110)
-25.5 (-110)
O 54.5 (-115)
U 54.5 (-105)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+230
-285
+7 (-105)
-7 (-115)
O 43.5 (-110)
U 43.5 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-500
+380
-12.5 (-108)
+12.5 (-112)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-180
+150
-3.5 (-108)
+3.5 (-112)
O 53.5 (-115)
U 53.5 (-105)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+600
-900
+17.5 (-110)
-17.5 (-110)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-625
 
-14.5 (-108)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+180
-218
+4.5 (-105)
-4.5 (-115)
O 54.5 (-108)
U 54.5 (-112)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-155
+3 (-112)
-3 (-108)
O 56.5 (-115)
U 56.5 (-105)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
-105
-115
+1.5 (-115)
-1.5 (-105)
O 56.5 (-112)
U 56.5 (-108)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+310
-395
+9.5 (-110)
-9.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-410
+320
-10.5 (-110)
+10.5 (-110)
O 49.5 (-105)
U 49.5 (-115)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-112)
-3 (-108)
O 61.5 (-112)
U 61.5 (-108)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+275
-345
+9.5 (-112)
-9.5 (-108)
O 39.5 (-108)
U 39.5 (-112)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-485
+370
-12.5 (-110)
+12.5 (-110)
O 47.5 (-108)
U 47.5 (-112)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+124
-148
+2.5 (-102)
-2.5 (-118)
O 48.5 (-112)
U 48.5 (-108)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-238
+195
-6 (-112)
+6 (-108)
O 53.5 (-112)
U 53.5 (-108)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+180
-218
+5.5 (-112)
-5.5 (-108)
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-102
-118
+1.5 (-115)
-1.5 (-105)
O 46.5 (-108)
U 46.5 (-112)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+455
-625
+15.5 (-108)
-15.5 (-112)
O 62.5 (-112)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+164
-198
+4.5 (-110)
-4.5 (-110)
O 53.5 (-115)
U 53.5 (-105)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-700
 
-16.5 (-108)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-155
+130
-3 (-110)
+3 (-110)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+114
-135
+2.5 (-110)
-2.5 (-110)
O 51.5 (-115)
U 51.5 (-105)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+205
-250
+6.5 (-108)
-6.5 (-112)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+102
 
+1.5 (-110)
 
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+340
 
+10.5 (-105)
 
O 50.5 (-112)
U 50.5 (-108)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+2800
-10000
+38.5 (-115)
-38.5 (-105)
O 56.5 (-108)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+154
-185
+4.5 (-110)
-4.5 (-110)
O 66.5 (-115)
U 66.5 (-105)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-270
+220
-7 (-105)
+7 (-115)
O 44.5 (-115)
U 44.5 (-105)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-650
+470
-15.5 (-110)
+15.5 (-110)
O 54.5 (-118)
U 54.5 (-102)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-108)
-33.5 (-112)
O 44.5 (-112)
U 44.5 (-108)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+280
-355
+8.5 (-108)
-8.5 (-112)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30.5 (-115)
-30.5 (-105)
O 45.5 (-105)
U 45.5 (-115)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 63.5 (-105)
U 63.5 (-115)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-625
+455
-14.5 (-105)
+14.5 (-115)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-142
+120
-2.5 (-115)
+2.5 (-105)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1400
-3200
+25.5 (-110)
-25.5 (-110)
O 55.5 (-102)
U 55.5 (-118)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+180
-218
+5.5 (-110)
-5.5 (-110)
O 46.5 (-112)
U 46.5 (-108)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-345
+275
-9.5 (-108)
+9.5 (-112)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+230
-285
+7.5 (-115)
-7.5 (-105)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+410
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-112)
U 49.5 (-108)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Louisville Cardinals vs. Miami Hurricanes on October 17, 2025 at Hard Rock Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN