Michigan vs USC Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 11)

Updated: 2025-10-04T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

Michigan heads west to take on USC on October 11, 2025, in a cross-country marquee clash that pits Michigan’s dominant run game and stout defense against USC’s explosive offense and balanced attack. USC opens as a slim favorite thanks to home-field and high-octane numbers — the Trojans average 48.4 points per game and 8.53 yards per play.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 11, 2025

Start Time: 7:30 PM EST​

Venue: United Airlines Field at the Los Angeles Memorial Coliseum​

Trojans Record: (4-1)

Wolverines Record: (4-1)

OPENING ODDS

MICH Moneyline: +105

USC Moneyline: -125

MICH Spread: +2.5

USC Spread: -2.5

Over/Under: 56.5

MICH
Betting Trends

  • Michigan enters this game having covered in 4 of its 5 played games under current lines, riding strong rushing performance and offensive consistency into its road contests.

USC
Betting Trends

  • USC has also been sharp against the spread at home, with five straight games showing them covering double-digit margins or holding late leads in tight ones.

MATCHUP TRENDS

  • USC’s red zone efficiency is nearly perfect — 96.55% of red-zone opportunities converted into touchdowns — making the margin for error especially small for Michigan’s defense. Meanwhile, USC’s offense has generated 8.53 yards per play, one of the highest marks in the nation, placing an extreme burden on Michigan’s ability to prevent big plays.

MICH vs. USC
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Haynes under 107.5 Rushing Yards.

LIVE CFB ODDS

CFB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
325-240
VAULT
NET UNITS
(INCL VIG)
+395.4
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$39,540
EXECUTIVE
VS. SPREAD
1593-1364
EXECUTIVE
NET UNITS
(INCL VIG)
+371.9
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$37,192

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Michigan vs USC Prediction & Odds:
Free CFB Betting Insights for 10/11/25

The October 11, 2025 matchup between the Michigan Wolverines and the USC Trojans at the Los Angeles Memorial Coliseum is a headline-making Big Ten clash that brings together two powerhouse programs built in completely different ways — Michigan with its bruising, methodical style and USC with its explosive, space-driven attack. It’s the kind of stylistic collision that defines conference races and playoff trajectories. Michigan enters the contest at 4–0 and has been as steady as ever under Sherrone Moore, who has seamlessly maintained the identity Jim Harbaugh built: control the trenches, dominate time of possession, and suffocate opponents defensively. The Wolverines are averaging 6.67 yards per carry on 1,014 rushing yards through four games, leaning on their elite offensive line and deep backfield led by Justice Haynes, Donovan Edwards, and Kalel Mullings. Quarterback Bryce Underwood, the true freshman phenom, has shown flashes of brilliance while playing within his role — efficient, composed, and mistake-free — completing over 65% of his passes for 733 yards, four touchdowns, and only one interception. Michigan’s formula has remained simple but brutally effective: pound the rock, stay ahead of the chains, and force opponents into frustration. Their red zone success rate (92.9%) and third-down conversion rate (42%) speak to their offensive efficiency, while their defense continues to play at an elite level, allowing just 4.24 yards per play and ranking near the top of the nation in scoring defense. The Wolverines’ front seven, anchored by Mason Graham and Kenneth Grant, has been ferocious in collapsing pockets and shutting down opposing run games, while cornerbacks Will Johnson and Amorion Walker headline a secondary that thrives on discipline and anticipation. But facing USC represents an entirely different challenge — a track-meet offense that thrives on speed, misdirection, and explosive playmaking.

The Trojans enter averaging a staggering 48.4 points per game and 8.53 yards per play, led by one of the most efficient quarterbacks in the country and a deep stable of skill players who can score from anywhere on the field. Their third-down efficiency (56.3%) and near-perfect red zone rate (96.6%) demonstrate their ability to sustain drives and finish them. Under Lincoln Riley, USC’s offense has been almost surgical, blending RPO concepts, vertical route trees, and tempo to stress defenses. Running backs Quinten Joyner and MarShawn Lloyd have added balance to the attack, combining for over 700 rushing yards and seven touchdowns through five games, while the receiving corps — highlighted by Zachariah Branch, Duce Robinson, and Tahj Washington — offers mismatches across every level. The key matchup will be Michigan’s defensive front against USC’s tempo offense: if Michigan can win first down and force the Trojans into third-and-long situations, they can neutralize the home team’s rhythm. But if USC dictates pace early and forces the Wolverines’ defense to play in space, Michigan’s physical advantage could erode as the game progresses. Expect Michigan to lean on its ground game to keep USC’s offense on the sideline and shorten possessions, while USC will aim for explosive plays to build momentum and force Michigan to chase the scoreboard. Special teams could also play a pivotal role, as both programs feature reliable kickers and dangerous returners. Ultimately, this game will hinge on execution and tempo — Michigan’s patience and physicality against USC’s speed and precision. It’s a true clash of identities, and whichever side imposes its style for the longest stretches will likely walk away with a victory that reverberates far beyond mid-October.

Michigan Wolverines CFB Preview

The Michigan Wolverines head west to Los Angeles on October 11, 2025, in what promises to be one of the season’s most compelling Big Ten matchups as they take on the USC Trojans at the Coliseum. For Michigan, this game is not just about maintaining their unbeaten record but about asserting that their physical, ground-and-pound identity can travel and prevail against one of the nation’s most explosive offenses. Under head coach Sherrone Moore, the Wolverines have continued their signature formula of power running, clock control, and elite defense. Michigan enters this contest averaging 6.67 yards per rush with 1,014 total rushing yards through four games, led by a three-headed backfield featuring Justice Haynes, Donovan Edwards, and Kalel Mullings. That stable, running behind what many consider the best offensive line in the country, has allowed freshman quarterback Bryce Underwood to settle comfortably into a game-manager role while still flashing moments of high-level talent. Underwood has thrown for 733 yards and four touchdowns with just one interception, executing the play-action game effectively and showing poise under pressure. Michigan’s offensive success has come through efficiency, not explosiveness — they’ve converted 42% of third downs and scored on 93% of red-zone trips, relying on precision and patience to break down defenses. However, facing USC’s lightning-fast offense means Michigan’s ball-control strategy will be more important than ever; sustaining long drives and winning time of possession will be critical in keeping USC’s dynamic attack on the sidelines.

Defensively, Michigan continues to look like a championship-caliber unit, allowing just 4.24 yards per play and ranking among the top ten nationally in both scoring and total defense. The front seven, led by Mason Graham, Kenneth Grant, and linebacker Ernest Hausmann, has been exceptional in controlling the line of scrimmage, generating pressure without overcommitting blitzes, and dominating against the run. Their discipline and gap integrity will be vital against USC’s balanced offense, which can punish over-pursuit with RPOs and perimeter screens. The secondary, anchored by Will Johnson and Makari Paige, will face its toughest test of the year against a Trojan passing attack averaging over 300 yards per game and featuring speed at every receiver position. Michigan’s defense thrives on forcing opponents into third-and-medium situations, where they can disguise coverage and dictate tempo, but the Wolverines cannot afford communication lapses against an offense that strikes quickly and punishes mistakes. Special teams could quietly play a pivotal role, as Michigan’s kicker James Turner has been automatic inside 45 yards, and punter Tommy Doman’s precision could pin USC deep and help the Wolverines win the field-position battle. Emotionally, Michigan will need to stay composed amid the energy of the Coliseum and the Trojans’ fast tempo. If the Wolverines can establish their run early, convert red-zone opportunities into touchdowns, and force USC to play patient, structured football, they’ll be in position to grind out a statement road victory. But if they get dragged into a shootout, the matchup could tilt toward USC’s strengths. Michigan’s path to success is simple: dominate the trenches, control the pace, and turn this game into a test of endurance rather than speed. If they do, their power and poise could silence the Coliseum and keep their playoff push rolling.

Michigan heads west to take on USC on October 11, 2025, in a cross-country marquee clash that pits Michigan’s dominant run game and stout defense against USC’s explosive offense and balanced attack. USC opens as a slim favorite thanks to home-field and high-octane numbers — the Trojans average 48.4 points per game and 8.53 yards per play. Michigan vs USC AI Prediction: Free CFB Betting Insights for Oct 11. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

USC Trojans CFB Preview

The USC Trojans return to the Los Angeles Memorial Coliseum on October 11, 2025, for a marquee Big Ten showdown against the Michigan Wolverines in what could be one of the defining games of their first full season in the conference. Head coach Lincoln Riley’s team has dazzled offensively through five games, averaging an astounding 48.4 points per contest and a blistering 8.53 yards per play — numbers that speak to their precision, creativity, and explosiveness. USC’s offense remains one of the most dangerous in college football, combining speed at every position with exceptional quarterback efficiency. The Trojans have passed for 1,690 yards, thrown 12 touchdowns, and surrendered just one interception this season, while also maintaining a strong ground balance with 923 rushing yards at 6.41 yards per carry. Riley’s system continues to thrive on quick reads, tempo, and deep route combinations that stretch defenses horizontally and vertically, making it incredibly difficult for even elite defensive units to keep up for four quarters. Quarterback Malachi Nelson, taking over for Caleb Williams, has quickly proven himself as a polished successor — calm in the pocket, deadly accurate, and unafraid to test tight windows. His connection with wide receivers Zachariah Branch and Duce Robinson has elevated the offense, while running backs Quinten Joyner and MarShawn Lloyd have brought power and explosiveness to the backfield rotation. USC’s offensive line has also taken a noticeable step forward, both in protection and run blocking, providing Nelson ample time to execute Riley’s intricate passing designs. But for all the offensive fireworks, USC’s defense has been the key to their rise in 2025. After years of being criticized for inconsistency, the Trojans have become more disciplined under new defensive coordinator D’Anton Lynn, holding opponents to an average of 19 points per game.

They’ve been especially effective on third down, allowing just 32% conversions, and have created havoc with 103 tackles for loss, six sacks, and five interceptions through five contests. Linebacker Eric Gentry has been the emotional centerpiece, while edge rusher Jamil Muhammad has been relentless in collapsing pockets. The secondary, led by cornerback Jacobe Covington and safety Zion Branch, will face its toughest challenge yet against Michigan’s physical play-action game. The key for USC defensively will be stopping the Wolverines’ rushing attack early and forcing freshman quarterback Bryce Underwood into passing situations where the Trojans can unleash pressure. Offensively, USC’s tempo and versatility could give Michigan fits — if the Trojans can force mismatches in space and push the pace, they could neutralize Michigan’s physical advantage and wear down their defensive front. Special teams have also been a quiet strength, with kicker Denis Lynch remaining perfect on the season and Zachariah Branch providing elite explosiveness in the return game. For USC, this game is about validation — proving that their offense can thrive against an elite, physical Big Ten defense and that their rebuilt defense can handle a smashmouth opponent. The Coliseum crowd will play its part, as the Trojans have been virtually unbeatable at home under Riley. Expect USC to come out fast, look to score early, and maintain aggression throughout. If the Trojans’ offensive execution stays sharp and their defense contains Michigan’s run game just enough, this could be another showcase win that cements USC as not just a flashy team but a legitimate playoff contender.

Michigan vs. USC Prop Picks (AI)

AI algorithm Remi is pouring through mountains of stats on each team. In fact, anytime the Wolverines and Trojans play there’s always several intriguing angles to key in on. Not to mention games played at United Airlines Field at the Los Angeles Memorial Coliseum in Oct seemingly never follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: J. Haynes under 107.5 Rushing Yards.

Michigan vs. USC Prediction (AI)

Remi Robot Icon

Remi, our AI sports genius, has been pouring over tons of data from every angle between the Wolverines and Trojans and using recursive machine learning and industry leading AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most fixated on the trending weight knucklehead sportsbettors tend to put on coaching factors between a Wolverines team going up against a possibly unhealthy Trojans team. It appears the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Michigan vs USC picks, computer picks Wolverines vs Trojans, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Wolverines Betting Trends

Michigan enters this game having covered in 4 of its 5 played games under current lines, riding strong rushing performance and offensive consistency into its road contests.

Trojans Betting Trends

USC has also been sharp against the spread at home, with five straight games showing them covering double-digit margins or holding late leads in tight ones.

Wolverines vs. Trojans Matchup Trends

USC’s red zone efficiency is nearly perfect — 96.55% of red-zone opportunities converted into touchdowns — making the margin for error especially small for Michigan’s defense. Meanwhile, USC’s offense has generated 8.53 yards per play, one of the highest marks in the nation, placing an extreme burden on Michigan’s ability to prevent big plays.

Michigan vs. USC Game Info

Michigan vs USC starts on October 11, 2025 at 7:30 PM EST.

Venue: United Airlines Field at the Los Angeles Memorial Coliseum.

Spread: USC -2.5
Moneyline: Michigan +105, USC -125
Over/Under: 56.5

Michigan: (4-1)  |  USC: (4-1)

Remi's searched hard and found the best prop for this matchup: J. Haynes under 107.5 Rushing Yards.. Prices move—always shop for the best number.

USC’s red zone efficiency is nearly perfect — 96.55% of red-zone opportunities converted into touchdowns — making the margin for error especially small for Michigan’s defense. Meanwhile, USC’s offense has generated 8.53 yards per play, one of the highest marks in the nation, placing an extreme burden on Michigan’s ability to prevent big plays.

MICH trend: Michigan enters this game having covered in 4 of its 5 played games under current lines, riding strong rushing performance and offensive consistency into its road contests.

USC trend: USC has also been sharp against the spread at home, with five straight games showing them covering double-digit margins or holding late leads in tight ones.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Michigan vs. USC Odds

AI algorithm Remi is pouring through mountains of stats on each line. In fact, anytime the Michigan vs USC trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable betting trends.

Michigan vs USC Opening Odds

MICH Moneyline: +105
USC Moneyline: -125
MICH Spread: +2.5
USC Spread: -2.5
Over/Under: 56.5

Michigan vs USC Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-360
 
-9.5 (-105)
O 55 (-118)
U 55 (-107)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-115
-105
-1 (-110)
+1 (-110)
O 51 (-110)
U 51 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-240
+185
-6.5 (-112)
+6.5 (-109)
O 56 (-110)
U 56 (-112)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4500
+1550
-26.5 (-110)
+26.5 (-110)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+160
-205
+4.5 (-110)
-4.5 (-110)
O 50 (-112)
U 50 (-110)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1700
+950
-21.5 (-110)
+21.5 (-110)
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-400
+310
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-305
+240
-7.5 (-105)
+7.5 (-115)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+115
-2.5 (-110)
+2.5 (-110)
O 58.5 (-110)
U 58.5 (-110)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-210
+175
-5 (-110)
+5 (-110)
O 63.5 (-110)
U 63.5 (-110)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1200
-5000
+25.5 (-113)
-25.5 (-108)
O 54.5 (-115)
U 54.5 (-106)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+228
-285
+7 (-110)
-7 (-110)
O 43 (-110)
U 43 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-480
+360
-12.5 (-110)
+12.5 (-110)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-175
+148
-3.5 (-110)
+3.5 (-110)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+600
-1000
+17.5 (-112)
-17.5 (-109)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-600
 
-14.5 (-110)
O 63 (-110)
U 63 (-110)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+180
-220
+5 (-110)
-5 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-155
+3 (-110)
-3 (-110)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
+100
-120
+1 (-110)
-1 (-110)
O 57 (-110)
U 57 (-110)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+285
-365
+9.5 (-110)
-9.5 (-110)
O 48 (-115)
U 48 (-105)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-420
+320
-10.5 (-115)
+10.5 (-105)
O 49 (-110)
U 49 (-110)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-110)
-3 (-110)
O 61.5 (-110)
U 61.5 (-110)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+270
-345
+8.5 (-110)
-8.5 (-110)
O 39 (-110)
U 39 (-110)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-480
+360
-12 (-110)
+12 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+120
-152
+2.5 (-105)
-2.5 (-117)
O 48.5 (-115)
U 48.5 (-106)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-225
+185
-6 (-110)
+6 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+175
-210
+5.5 (-110)
-5.5 (-110)
O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-105
-115
+1 (-110)
-1 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+475
-750
+15.5 (-110)
-15.5 (-110)
O 62.5 (-113)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+162
-195
+4.5 (-110)
-4.5 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-800
 
-16.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-155
+130
-3 (-110)
+3 (-110)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+118
-140
+2.5 (-110)
-2.5 (-110)
O 52.5 (-105)
U 52.5 (-115)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+200
-260
+6.5 (-107)
-6.5 (-114)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+105
 
+1.5 (-110)
 
O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+335
 
+11 (-110)
 
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+2800
-10000
+38.5 (-114)
-38.5 (-107)
O 56.5 (-110)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+162
-195
+4.5 (-110)
-4.5 (-110)
O 67.5 (-110)
U 67.5 (-110)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-267
+215
-7 (-105)
+7 (-115)
O 44.5 (-115)
U 44.5 (-105)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-750
+450
-15.5 (-110)
+15.5 (-110)
O 55.5 (-107)
U 55.5 (-114)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-110)
-33.5 (-110)
O 44.5 (-110)
U 44.5 (-110)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+270
-345
+9.5 (-110)
-9.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30 (-109)
-30 (-112)
O 45.5 (-112)
U 45.5 (-109)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 62.5 (-110)
U 62.5 (-110)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-650
+460
-14.5 (-115)
+14.5 (-105)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-145
+122
-2.5 (-115)
+2.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1350
-3500
+25.5 (-110)
-25.5 (-110)
O 55 (-110)
U 55 (-110)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+185
-225
+5.5 (-110)
-5.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-360
+275
-9.5 (-107)
+9.5 (-114)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+235
-310
+7.5 (-115)
-7.5 (-107)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+400
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Michigan Wolverines vs. USC Trojans on October 11, 2025 at United Airlines Field at the Los Angeles Memorial Coliseum.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN