Iowa State vs Colorado Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 11)

Updated: 2025-10-04T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

Iowa State (5–0) heads to Boulder on October 11, 2025, in search of a Big 12 statement win over a Colorado team still trying to find stability under new leadership. Colorado (2–3) will lean on its offense—now quarterbacked by transfer Kaidon Salter—and home-field energy to disrupt Iowa State’s high-flying attack.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 11, 2025

Start Time: 3:30 PM EST​

Venue: Folsom Field​

Buffaloes Record: (2-4)

Cyclones Record: (5-1)

OPENING ODDS

IOWAST Moneyline: -181

COLO Moneyline: +150

IOWAST Spread: -4.5

COLO Spread: +4.5

Over/Under: 52.5

IOWAST
Betting Trends

  • Iowa State enters the game averaging 31.6 points per game and has been solid in efficiency and margin, making it a favorite in many betting markets so far.

COLO
Betting Trends

  • Colorado has had inconsistent results in 2025, particularly at home, but its return to strong passing metrics under Salter has drawn increased betting interest in its implied upside.

MATCHUP TRENDS

  • Colorado’s offense has averaged about 5.97 yards per play while scoring 25.8 points per game, compared to Iowa State’s 5.92 yards per play and 31.6 PPG—on paper they’re remarkably close in efficiency.

IOWAST vs. COLO
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: B. Eskildsen under 48.5 Receiving Yards.

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Iowa State vs Colorado Prediction & Odds:
Free CFB Betting Insights for 10/11/25

The October 11, 2025 showdown between the Iowa State Cyclones and the Colorado Buffaloes at Folsom Field brings together two programs on very different paths, yet both with plenty to prove in the heart of Big 12 play. Iowa State enters unbeaten at 5–0, playing its most balanced football under head coach Matt Campbell in years, while Colorado sits at 2–3, still searching for rhythm and defensive stability under its new leadership and first-year starting quarterback Kaidon Salter. The Cyclones have built their success on execution and discipline, averaging 31.6 points per game while allowing just 14.2, a combination that has made them one of the most efficient two-way teams in the conference. Quarterback Rocco Becht has emerged as a confident, steady hand, orchestrating an offense that marries controlled passing with an opportunistic ground game. Becht has thrown for over 1,100 yards with minimal turnovers, spreading the ball across a deep group of receivers led by Jayden Higgins and Jaylin Noel, while running backs Abu Sama III and Eli Sanders have combined for more than 700 rushing yards and 12 touchdowns behind a line that has steadily improved at opening interior lanes. The Cyclones’ offensive approach is methodical, built to sustain drives and wear down opponents rather than rely on explosive plays, though they have shown they can strike quickly when defenses overcommit. On the other side, Iowa State’s defense continues to be its calling card. Coordinator Jon Heacock’s 3-3-5 scheme remains one of the most adaptable in college football, thriving on gap integrity, disguised pressures, and disciplined tackling. Linebacker Caleb Bacon has been a breakout star, leading a front seven that has made life miserable for opposing quarterbacks, while cornerback Jeremiah Cooper anchors a secondary that has allowed very few completions over 20 yards this season.

That defense will be tested against a Colorado offense that, while inconsistent, has started to find flashes of identity under Salter, the transfer from Liberty. Salter brings dual-threat athleticism and an aggressive downfield mindset that has given the Buffaloes big-play potential, averaging nearly six yards per play despite frequent breakdowns in pass protection. Wide receivers Travis Hunter and Jimmy Horn Jr. provide legitimate threats on the perimeter, and running back Alton McCaskill IV offers a reliable check-down option out of the backfield. For Colorado to compete, they’ll need their offensive line to protect Salter better than it has all season and sustain drives long enough to keep Iowa State’s offense off the field. Defensively, the Buffaloes have struggled, surrendering over 25 points per game and showing vulnerability against physical rushing attacks, which could spell trouble against Iowa State’s downhill running scheme. Colorado’s defensive front, led by Shane Cokes and linebacker LaVonta Bentley, will need to generate pressure without sacrificing gap control, while the secondary must tackle cleanly against Iowa State’s short passing game. The altitude in Boulder may provide a minor conditioning edge for the home team, but Iowa State’s depth and discipline should mitigate that advantage. Expect the Cyclones to play their usual brand of football—efficient, physical, and turnover-averse—forcing Colorado to execute consistently rather than rely on splash plays. If Becht can stay clean, the running game remains effective, and the defense limits Salter’s improvisation, Iowa State has the makeup to control this contest from start to finish. Colorado, meanwhile, will need an early spark—perhaps a turnover or special teams play—to shift momentum and keep the home crowd engaged. Ultimately, this matchup is a test of stability versus volatility: Iowa State’s structure and discipline against Colorado’s explosiveness and unpredictability, with the Cyclones’ balance giving them a clear edge in a game that could serve as a defining moment for both teams’ seasons.

Iowa State Cyclones CFB Preview

The Iowa State Cyclones enter their October 11, 2025 road matchup against the Colorado Buffaloes in Boulder with confidence, discipline, and one of the most balanced rosters in the Big 12. Under head coach Matt Campbell, the Cyclones have quietly crafted an undefeated start built on physical defense, mistake-free offense, and a methodical approach that wears opponents down over four quarters. Iowa State’s identity this season has been its balance — averaging 31.6 points per game while allowing just 14.2 — a combination that speaks to their consistency on both sides of the ball. Quarterback Rocco Becht has emerged as the steady hand guiding this offense, showing poise under pressure and precision in decision-making. He’s thrown for over 1,100 yards while keeping turnovers to a minimum, utilizing a deep receiving corps led by Jayden Higgins and Jaylin Noel. Their chemistry has given the Cyclones a reliable passing rhythm that complements their hard-nosed rushing attack, which has produced over 750 yards and 12 touchdowns through five games. Running backs Abu Sama III and Eli Sanders bring contrasting styles — Sama’s explosiveness in open space balanced by Sanders’ physicality between the tackles — and together, they form one of the more efficient backfields in the conference. Iowa State’s offensive line, often overlooked, has been the unsung hero of this hot start, controlling the line of scrimmage and allowing the offense to sustain drives that keep their elite defense fresh.

Defensively, the Cyclones remain one of the toughest, most organized units in college football under long-time coordinator Jon Heacock. His 3-3-5 system continues to be a masterclass in adaptability — built to limit explosive plays while forcing opponents into long, inefficient drives. Linebacker Caleb Bacon has emerged as the emotional and tactical leader of the defense, flying sideline to sideline while anchoring a front seven that allows fewer than 100 rushing yards per game. The secondary, led by safety Jeremiah Cooper, has been exceptional at reading quarterbacks and closing on the ball, holding opponents to one of the lowest passing success rates in the conference. Against Colorado’s new-look offense, Iowa State’s defensive discipline will be tested by the dual-threat ability of quarterback Kaidon Salter, whose mobility and deep-ball aggression can stress defensive spacing. The Cyclones will aim to contain Salter’s scrambles, limit yards after catch, and force him to make plays from the pocket, where their disguised pressures and coverage rotations can confuse even seasoned passers. On special teams, kicker Chase Contreraz and punter Tyler Perkins have been consistent weapons, helping Iowa State win the field position battle nearly every week. The Cyclones’ path to victory in Boulder hinges on execution and control — establish the run early, keep Becht upright, and avoid giving Colorado’s offense short fields or explosive momentum shifts. Playing at altitude presents an endurance challenge, but Iowa State’s depth, conditioning, and commitment to physical football should mitigate those factors. Expect Campbell’s team to rely on its tried-and-true formula: play clean, sustain drives, and let the defense suffocate the opponent’s rhythm. If the Cyclones maintain their composure and continue playing within their identity, they have every opportunity to leave Boulder with another decisive road win and remain squarely in the Big 12 title conversation.

Iowa State (5–0) heads to Boulder on October 11, 2025, in search of a Big 12 statement win over a Colorado team still trying to find stability under new leadership. Colorado (2–3) will lean on its offense—now quarterbacked by transfer Kaidon Salter—and home-field energy to disrupt Iowa State’s high-flying attack. Iowa State vs Colorado AI Prediction: Free CFB Betting Insights for Oct 11. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Colorado Buffaloes CFB Preview

The Colorado Buffaloes return to Folsom Field on October 11, 2025, looking to turn potential into production and pull off a statement win against an undefeated Iowa State squad that thrives on structure and efficiency. After a turbulent start to the season, Colorado enters this matchup at 2–3, still adjusting to its revamped roster and new quarterback Kaidon Salter, a transfer from Liberty whose dual-threat ability has begun to give the Buffaloes’ offense a spark. Salter’s mobility and arm strength have allowed Colorado to stretch defenses vertically while creating second-chance opportunities on broken plays, a dimension that was sorely missing in last year’s attack. Through five games, the Buffaloes are averaging just under 26 points per contest and 5.97 yards per play, a sign that their offensive efficiency has quietly improved even if the scoreboard hasn’t always reflected it. Head coach Deion Sanders’ staff has emphasized tempo and spacing, giving Salter the freedom to improvise when the pocket collapses, which could be crucial against an Iowa State defense that thrives on pressure and confusion. The offense flows through Salter’s playmaking, but his supporting cast will need to step up for Colorado to keep pace. Wideouts Travis Hunter and Jimmy Horn Jr. headline a talented receiving group capable of winning one-on-one matchups, while running back Alton McCaskill IV provides balance as both a rusher and receiver out of the backfield. Colorado’s offensive line has been its biggest question mark, struggling with consistency and allowing too many negative plays, but when the unit gives Salter time, the Buffaloes can move the ball on anyone. Against Iowa State’s disciplined 3-3-5 defense, Colorado must sustain drives and avoid turnovers—something they’ve struggled with in conference play. The key will be staying on schedule: running efficiently on early downs, taking what the defense gives them, and avoiding the third-and-long situations that Iowa State feasts on. Defensively, Colorado’s challenge is monumental.

The Buffaloes have allowed over 25 points per game, and stopping Iowa State’s balanced offense will require their best effort of the season. Defensive linemen Shane Cokes and Amari McNeill will need to generate pressure up front to disrupt quarterback Rocco Becht’s timing, while linebackers LaVonta Bentley and Brendan Gant must play sound gap football against a Cyclone rushing attack that has churned out over 700 yards through five games. In the secondary, cornerback Cormani McClain and safety Shilo Sanders will be tasked with containing Iowa State’s dynamic receiving duo of Jayden Higgins and Jaylin Noel, both of whom excel in finding soft spots in coverage. For Colorado to have a chance, it must win situational downs, hold firm in the red zone, and generate at least one turnover to swing momentum. The altitude advantage and home crowd energy in Boulder could play a role, especially if the Buffaloes start fast and put pressure on Iowa State to respond. Special teams, an area of quiet improvement for Colorado this season, could also tilt the field; kicker Alejandro Mata has been reliable, and Hunter remains a threat in the return game. Ultimately, this game is a measuring stick for where Sanders’ program stands against one of the Big 12’s most disciplined teams. If Colorado can protect Salter, limit Iowa State’s early scoring drives, and use tempo to keep the Cyclones off balance, the Buffaloes could make this a four-quarter fight. But if they fall behind early or lose the turnover battle, Iowa State’s composure and defensive structure could quickly take over. For a program still finding its footing, a win here would not only steady the season but also signal that Colorado’s rebuild is beginning to take root.

Iowa State vs. Colorado Prop Picks (AI)

Remi is pouring through tons of stats on each team. In fact, anytime the Cyclones and Buffaloes play there’s always several intriguing angles to key in on. Not to mention games played at Folsom Field in Oct seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: B. Eskildsen under 48.5 Receiving Yards.

Iowa State vs. Colorado Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over exorbitant amounts of data from every past game between the Cyclones and Buffaloes and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most keyed in on the trending emphasis emotional bettors regularly put on Iowa State’s strength factors between a Cyclones team going up against a possibly tired Buffaloes team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Iowa State vs Colorado picks, computer picks Cyclones vs Buffaloes, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Cyclones Betting Trends

Iowa State enters the game averaging 31.6 points per game and has been solid in efficiency and margin, making it a favorite in many betting markets so far.

Buffaloes Betting Trends

Colorado has had inconsistent results in 2025, particularly at home, but its return to strong passing metrics under Salter has drawn increased betting interest in its implied upside.

Cyclones vs. Buffaloes Matchup Trends

Colorado’s offense has averaged about 5.97 yards per play while scoring 25.8 points per game, compared to Iowa State’s 5.92 yards per play and 31.6 PPG—on paper they’re remarkably close in efficiency.

Iowa State vs. Colorado Game Info

Iowa State vs Colorado starts on October 11, 2025 at 3:30 PM EST.

Spread: Colorado +4.5
Moneyline: Iowa State -181, Colorado +150
Over/Under: 52.5

Iowa State: (5-1)  |  Colorado: (2-4)

Remi's searched hard and found the best prop for this matchup: B. Eskildsen under 48.5 Receiving Yards.. Prices move—always shop for the best number.

Colorado’s offense has averaged about 5.97 yards per play while scoring 25.8 points per game, compared to Iowa State’s 5.92 yards per play and 31.6 PPG—on paper they’re remarkably close in efficiency.

IOWAST trend: Iowa State enters the game averaging 31.6 points per game and has been solid in efficiency and margin, making it a favorite in many betting markets so far.

COLO trend: Colorado has had inconsistent results in 2025, particularly at home, but its return to strong passing metrics under Salter has drawn increased betting interest in its implied upside.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Iowa State vs. Colorado Odds

Remi is pouring through mountains of data points on each player. In fact, anytime the Iowa State vs Colorado trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable betting trends.

Iowa State vs Colorado Opening Odds

IOWAST Moneyline: -181
COLO Moneyline: +150
IOWAST Spread: -4.5
COLO Spread: +4.5
Over/Under: 52.5

Iowa State vs Colorado Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-360
 
-9.5 (-108)
O 55.5 (-108)
U 55.5 (-112)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-110
-110
-1.5 (-102)
+1.5 (-118)
O 50.5 (-112)
U 50.5 (-108)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-230
+190
-6.5 (-112)
+6.5 (-108)
O 55.5 (-112)
U 55.5 (-108)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4000
+1600
-26.5 (-112)
+26.5 (-108)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+164
-198
+4.5 (-110)
-4.5 (-110)
O 50.5 (-108)
U 50.5 (-112)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1800
+1000
-21.5 (-105)
+21.5 (-115)
O 50.5 (-108)
U 50.5 (-112)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-395
+310
-10.5 (-108)
+10.5 (-112)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-285
+230
-7.5 (-105)
+7.5 (-115)
O 48.5 (-108)
U 48.5 (-112)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+114
-2.5 (-112)
+2.5 (-108)
O 58.5 (-112)
U 58.5 (-108)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-205
+170
-4.5 (-112)
+4.5 (-108)
O 63.5 (-108)
U 63.5 (-112)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1400
-3200
+25.5 (-115)
-25.5 (-105)
O 54.5 (-115)
U 54.5 (-105)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+240
-298
+7.5 (-112)
-7.5 (-108)
O 43.5 (-110)
U 43.5 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-455
+350
-12.5 (-108)
+12.5 (-112)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-170
+142
-3.5 (-105)
+3.5 (-115)
O 54.5 (-105)
U 54.5 (-115)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+625
-950
+17.5 (-110)
-17.5 (-110)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-625
 
-14.5 (-108)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+170
-205
+4.5 (-105)
-4.5 (-115)
O 54.5 (-108)
U 54.5 (-112)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+124
-148
+3 (-112)
-3 (-108)
O 56.5 (-115)
U 56.5 (-105)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
-105
-115
+1.5 (-115)
-1.5 (-105)
O 56.5 (-112)
U 56.5 (-108)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+285
-360
+9.5 (-110)
-9.5 (-110)
O 47.5 (-108)
U 47.5 (-112)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-395
+310
-10.5 (-110)
+10.5 (-110)
O 49.5 (-105)
U 49.5 (-115)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-112)
-3 (-108)
O 61.5 (-112)
U 61.5 (-108)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+275
-345
+8.5 (-108)
-8.5 (-112)
O 39.5 (-108)
U 39.5 (-112)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-455
+350
-12.5 (-110)
+12.5 (-110)
O 47.5 (-108)
U 47.5 (-112)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+124
-148
+2.5 (-102)
-2.5 (-118)
O 48.5 (-112)
U 48.5 (-108)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-230
+190
-6 (-110)
+6 (-110)
O 53.5 (-112)
U 53.5 (-108)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+185
-225
+5.5 (-112)
-5.5 (-108)
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-108
-112
+1.5 (-115)
-1.5 (-105)
O 46.5 (-108)
U 46.5 (-112)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+455
-625
+15.5 (-108)
-15.5 (-112)
O 62.5 (-112)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+164
-198
+4.5 (-110)
-4.5 (-110)
O 53.5 (-115)
U 53.5 (-105)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-675
 
-16.5 (-108)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-148
+124
-3 (-105)
+3 (-115)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+120
-142
+2.5 (-105)
-2.5 (-115)
O 52.5 (-105)
U 52.5 (-115)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+205
-250
+6.5 (-108)
-6.5 (-112)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+102
 
+1.5 (-110)
 
O 41.5 (-108)
U 41.5 (-112)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+340
 
+10.5 (-105)
 
O 50.5 (-112)
U 50.5 (-108)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+3000
-10000
+37.5 (-102)
-37.5 (-118)
O 56.5 (-108)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+160
-192
+4 (-108)
-4 (-112)
O 66.5 (-115)
U 66.5 (-105)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-265
+215
-7 (-105)
+7 (-115)
O 45.5 (-105)
U 45.5 (-115)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-650
+470
-15.5 (-110)
+15.5 (-110)
O 55.5 (-102)
U 55.5 (-118)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+32.5 (-105)
-32.5 (-115)
O 44.5 (-112)
U 44.5 (-108)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+280
-355
+8.5 (-108)
-8.5 (-112)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+2000
-10000
+30.5 (-115)
-30.5 (-105)
O 45.5 (-105)
U 45.5 (-115)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 63.5 (-105)
U 63.5 (-115)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-600
+440
-14 (-115)
+14 (-105)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-142
+120
-2.5 (-115)
+2.5 (-105)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1300
-2800
+25.5 (-110)
-25.5 (-110)
O 55.5 (-102)
U 55.5 (-118)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+180
-218
+5.5 (-110)
-5.5 (-110)
O 46.5 (-112)
U 46.5 (-108)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-345
+275
-9.5 (-108)
+9.5 (-112)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+230
-285
+7.5 (-115)
-7.5 (-105)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+410
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-112)
U 49.5 (-108)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-265
+215
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-205
+168
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-450
+340
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+146
-178
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Iowa State Cyclones vs. Colorado Buffaloes on October 11, 2025 at Folsom Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN