When Tulsa travels to Memphis on October 4, 2025, the matchup sets up as a classic case of a steady but flawed underdog trying to keep pace with one of the hottest teams in the American Conference, and the key question will be whether the Golden Hurricane can limit mistakes long enough to make things competitive against a Memphis squad that has looked dominant on both sides of the ball. The Tigers enter at 5–0 with one of the most impressive scoring margins in the country, averaging nearly 40 points per game while surrendering just 18, which speaks not only to their offensive firepower but also to their ability to consistently get stops and control momentum, and that balance has made them a nightmare opponent for teams that lack explosive playmaking. Their offense, led by quarterback Brendon Lewis and a deep cast of skill players, has been efficient in stretching defenses vertically while also showing enough balance to keep opponents from loading the box, and their third-down efficiency has allowed them to sustain drives and maximize possessions. Defensively, Memphis has thrived by forcing turnovers, limiting red-zone efficiency, and tackling well in space, which allows them to bottle up teams that rely on grinding drives to stay alive, and Tulsa fits that profile, making this an uphill battle for the visitors. The Golden Hurricane enter at 2–2, averaging just under 23 points per game while giving up a modest 20.5, but their offense has been inconsistent, with a rushing attack producing 4.7 yards per carry and a passing game that has been efficient in spurts but turnover-prone under pressure.

Their margin for error is slim, as Memphis has the ability to turn a single interception or fumble into a quick touchdown and swing momentum in front of a raucous home crowd. Tulsa’s best chance will be to slow the tempo, commit to the run, and lean on their defense to force Memphis into long drives, hoping to frustrate the Tigers into mistakes or at least limit possessions. Special teams will loom large as well, since Tulsa will need every hidden yard it can get, whether through coverage discipline or flipping field position with the punt game, while Memphis will want to avoid giving the underdog easy breaks in this department. From a betting standpoint, Memphis’s strong ATS record and dominant scoring margin suggest they will be sizable favorites, but games like this can tempt contrarian bettors toward Tulsa if the number grows too high, given that the Golden Hurricane’s defense has kept games closer than expected in spots. Ultimately, this game will likely hinge on whether Memphis can continue its pattern of fast starts and explosive scoring runs or whether Tulsa can drag the contest into a grind that minimizes possessions, as a shootout heavily favors the Tigers while a low-possession slugfest could be Tulsa’s only path to keeping things interesting in the fourth quarter.