Michigan State vs Nebraska Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 04)
Updated: 2025-09-27T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Michigan State Spartans travel to Lincoln, Nebraska on October 4, 2025 to take on the Cornhuskers in a marquee Big Ten showdown that mixes rebuilding narratives with high-stakes opportunity. Michigan State arrives with more consistency in recent seasons, while Nebraska is attempting to recapture relevance under Coach Matt Rhule, making this a pivotal test for both programs.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Oct 04, 2025
Start Time: 4:00 PM EST
Venue: Tom Osborne Field at Memorial Stadium
Cornhuskers Record: (3-1)
Spartans Record: (3-1)
OPENING ODDS
MICHST Moneyline: +330
NEB Moneyline: -429
MICHST Spread: +10.5
NEB Spread: -10.5
Over/Under: 53.5
MICHST
Betting Trends
- Michigan State’s 2025 campaign has thus far been marked by inconsistency in the betting markets, with the Spartans losing outright to 25 USC and failing to consistently cover large spreads in high-profile games.
NEB
Betting Trends
- Nebraska enters 2025 with a dominant offensive profile—averaging 43.5 points per game—but their ATS history remains mixed, as large home favorites in the Big Ten have not always delivered clean covers for the Cornhuskers in recent seasons.
MATCHUP TRENDS
- Oddsmakers have installed Nebraska as a sizable favorite in this matchup, likely in the double-digit range, which raises the classic underdog angle—if Michigan State keeps this close or forces turnovers, bettors may find value in the Spartans. Given Nebraska’s offensive explosiveness and MSU’s volatility in cover performance, the spread may invite sharp money on the underdog side.
MICHST vs. NEB
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: A. Chiles under 31.5 Rushing Yards.
LIVE CFB ODDS
CFB ODDS COMPARISON
WANT MORE AI PICKS?
VS. SPREAD
325-240
NET UNITS
(INCL VIG)
+395.4
NET PROFIT
(INCL VIG)
$100/UNIT
$39,540
VS. SPREAD
1593-1364
NET UNITS
(INCL VIG)
+371.9
NET PROFIT
(INCL VIG)
$100/UNIT
$37,192
AI SPORTS PICK PRODUCTS
Create a Free Account
‘Create an Account’ to Get Remi’s Picks Today. Remi Finds New Picks
Remi calculates the probability a team will cover the line. Remi Works 24/7
Remi uses this probability to assign units to each pick.
Get Remi's AI Picks
Get Remi’s Top AI Sports Picks sent direct to your inbox.
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
Michigan State vs Nebraska Prediction & Odds:
Free CFB Betting Insights for 10/4/25
On the other side, Nebraska’s balanced offense has been difficult to contain, as their line controls the trenches, their backs produce consistent yardage, and their passing game has been opportunistic enough to punish defenses that overcommit to the run. For Michigan State to compete, they must win the turnover battle, create disruptive plays on defense, and manufacture short fields through special teams or defensive takeaways, because long, sustained drives against Nebraska’s defense will be difficult. The Huskers, conversely, need to play with focus and avoid the complacency that sometimes strikes heavy favorites, ensuring they continue to execute cleanly on third downs and keep Michigan State from gaining confidence in the second half. The spread is expected to heavily favor Nebraska, but as always in conference play, underdogs can hang around if they manage to slow tempo and steal possessions, making this a potential trap game if the Cornhuskers look ahead. Still, the matchup leans strongly in Nebraska’s favor, as their combination of offensive firepower, defensive discipline, and home-field advantage should allow them to control momentum, dictate pace, and wear down a Michigan State team that is still trying to find consistency on both sides of the ball. Ultimately, the outcome will come down to whether Nebraska maintains its sharpness and finishes drives or whether Michigan State can disrupt rhythm, force mistakes, and turn this contest into a grind that stretches into the fourth quarter with the pressure shifting back onto the home team.
another full day of Spartan Dawgs in action 📺 pic.twitter.com/rnVSRpUEfp
— Michigan State Football (@MSU_Football) September 28, 2025
Michigan State Spartans CFB Preview
The Michigan State Spartans enter their October 4, 2025 trip to Lincoln knowing they face one of their toughest challenges of the season against a Nebraska team averaging 43.5 points per game and thriving under Matt Rhule, and for MSU the key will be discipline, poise, and finding ways to stretch the game into the fourth quarter while keeping the margin manageable. Michigan State sits at 3–1, showing promise in certain stretches but also vulnerability in their 45–31 loss to USC, where defensive breakdowns and inconsistent execution proved costly, and they cannot afford a similar letdown against a Cornhuskers team with the weapons to punish mistakes immediately. The Spartans’ offense revolves around quarterback Aidan Chiles, whose athleticism and arm talent give them options, but he must play efficiently, avoid turnovers, and use his legs strategically to extend drives and keep Nebraska’s aggressive defensive front from dictating tempo. With injuries and inexperience in the backfield, the ground game will need to be creative, relying on misdirection, play action, and screens to offset Nebraska’s strength in the trenches, and the offensive line must hold up long enough to give Chiles a chance to find receivers downfield.
Defensively, Michigan State must tighten up against the run and be aggressive in creating negative plays early in drives, because if Nebraska controls down-and-distance and opens up its playbook, the Spartans will be fighting uphill all game. Pressure packages and disguised coverages could help disrupt rhythm, but execution must be sharp, and they cannot afford to miss tackles or give up explosive plays in the secondary. Special teams will also be vital, as flipping field position or capitalizing on a momentum-shifting play in returns or coverage could be the difference between a close contest and Nebraska running away with it. From a betting perspective, Michigan State has been inconsistent against the spread, reflecting their volatility, and entering this matchup as a heavy underdog, their challenge is not only competing for a win but also showing enough resilience to stay within the number against a Nebraska team that has shown both offensive balance and defensive toughness. For MSU to succeed, they must lean on grit, play mistake-free football, and make Nebraska earn every yard while hoping their own offense can produce enough explosive plays to keep the Huskers honest. If the Spartans execute cleanly, limit penalties, and turn turnovers into points, they have an outside chance to push Nebraska into uncomfortable territory, but if they allow early momentum to snowball, the night in Lincoln could get away from them quickly.
Credit: USA TODAY/IMAGN
Nebraska Cornhuskers CFB Preview
The Nebraska Cornhuskers return to Memorial Stadium on October 4, 2025 carrying the momentum of a strong start to the season and the expectation of handling business against a Michigan State team still searching for consistency, and this game provides them a chance to reinforce their identity as one of the Big Ten’s most improved programs under Matt Rhule. Nebraska has been dominant through its first four games, averaging 43.5 points per game while surrendering only 13.5, a balance that highlights both their offensive explosiveness and their ability to clamp down defensively when opponents approach scoring range. Their offense has thrived on balance, with a physical ground attack that sets the tone and opens up opportunities in the passing game, where efficiency and discipline have limited turnovers and produced touchdowns at a high rate, allowing them to build comfortable margins early in games. Their offensive line has been one of their biggest assets, consistently winning trench battles and keeping quarterbacks upright, while the rotation of running backs has provided both power and speed, making them difficult to scheme against.
Defensively, the Huskers have been just as impressive, shutting down rushing lanes, applying relentless pressure up front, and playing disciplined coverage in the secondary, which has forced opponents into mistakes and stalled drives. At home, Nebraska feeds off one of the most passionate fan bases in the country, and the energy at Memorial Stadium has helped create an environment where opponents struggle to communicate and execute, especially on third downs. Against Michigan State, Nebraska’s mission will be to start fast, establish control at the line of scrimmage, and force the Spartans into a one-dimensional passing attack that plays directly into their defensive strength. Special teams, often a key factor in tight conference games, will also need to remain sharp, as avoiding miscues and maintaining strong coverage units will prevent Michigan State from generating the momentum swings they will desperately need as underdogs. From a betting perspective, Nebraska enters as a heavy favorite, and while that places pressure on them to deliver not just a win but also a convincing cover, their combination of offensive firepower and defensive discipline makes them well-positioned to meet those expectations if they execute. The formula for the Cornhuskers is straightforward: dominate the trenches, finish red-zone opportunities with touchdowns, and continue their defensive efficiency by keeping Michigan State from sustaining long drives. If they stick to that blueprint and avoid complacency, Nebraska should not only secure another victory but also deliver a statement performance that further cements their place among the Big Ten’s rising contenders in 2025.
Back at it.
— Nebraska Football (@HuskerFootball) September 29, 2025
🗓️ 10.4
⏰ 3:00 PM CT
🏟️ Memorial Stadium vs Michigan State
📺 @FS1 pic.twitter.com/fwEYbk4INf
Michigan State vs. Nebraska Prop Picks (AI)
Michigan State vs. Nebraska Prediction (AI)
Remi, our AI sports wizard, has been pouring over millions of data from every simulation between the Spartans and Cornhuskers and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
The Algorithm has been most keyed in on the trending factor knucklehead sportsbettors tend to put on Michigan State’s strength factors between a Spartans team going up against a possibly rested Cornhuskers team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Michigan State vs Nebraska picks, computer picks Spartans vs Cornhuskers, best bets, model edges, confidence ratings.
| DATE | GAME | LEAN | %WIN | UNITS | LEVEL | |
|---|---|---|---|---|---|---|
| CFB | 10/23 | SALA@GAST | UNLOCK THIS PICK | 4 |
EXECUTIVE
|
|
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Spartans Betting Trends
Michigan State’s 2025 campaign has thus far been marked by inconsistency in the betting markets, with the Spartans losing outright to 25 USC and failing to consistently cover large spreads in high-profile games.
Cornhuskers Betting Trends
Nebraska enters 2025 with a dominant offensive profile—averaging 43.5 points per game—but their ATS history remains mixed, as large home favorites in the Big Ten have not always delivered clean covers for the Cornhuskers in recent seasons.
Spartans vs. Cornhuskers Matchup Trends
Oddsmakers have installed Nebraska as a sizable favorite in this matchup, likely in the double-digit range, which raises the classic underdog angle—if Michigan State keeps this close or forces turnovers, bettors may find value in the Spartans. Given Nebraska’s offensive explosiveness and MSU’s volatility in cover performance, the spread may invite sharp money on the underdog side.
Michigan State vs. Nebraska Game Info
What time does Michigan State vs Nebraska start on October 04, 2025?
Michigan State vs Nebraska starts on October 04, 2025 at 4:00 PM EST.
Where is Michigan State vs Nebraska being played?
Venue: Tom Osborne Field at Memorial Stadium.
What are the opening odds for Michigan State vs Nebraska?
Spread: Nebraska -10.5
Moneyline: Michigan State +330, Nebraska -429
Over/Under: 53.5
What are the records for Michigan State vs Nebraska?
Michigan State: (3-1) | Nebraska: (3-1)
What is the AI best bet for Michigan State vs Nebraska?
Remi's searched hard and found the best prop for this matchup: A. Chiles under 31.5 Rushing Yards.. Prices move—always shop for the best number.
What are Michigan State vs Nebraska trending bets?
Oddsmakers have installed Nebraska as a sizable favorite in this matchup, likely in the double-digit range, which raises the classic underdog angle—if Michigan State keeps this close or forces turnovers, bettors may find value in the Spartans. Given Nebraska’s offensive explosiveness and MSU’s volatility in cover performance, the spread may invite sharp money on the underdog side.
What are Michigan State trending bets?
MICHST trend: Michigan State’s 2025 campaign has thus far been marked by inconsistency in the betting markets, with the Spartans losing outright to 25 USC and failing to consistently cover large spreads in high-profile games.
What are Nebraska trending bets?
NEB trend: Nebraska enters 2025 with a dominant offensive profile—averaging 43.5 points per game—but their ATS history remains mixed, as large home favorites in the Big Ten have not always delivered clean covers for the Cornhuskers in recent seasons.
Where can I find AI Picks for Michigan State vs Nebraska?
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
Michigan State vs. Nebraska Odds
AI algorithm Remi is pouring through tons of data points on each player. In fact, anytime the Michigan State vs Nebraska trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable patterns.
Michigan State vs Nebraska Opening Odds
MICHST Moneyline:
+330 NEB Moneyline: -429
MICHST Spread: +10.5
NEB Spread: -10.5
Over/Under: 53.5
Michigan State vs Nebraska Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
|
–
–
|
-5000
+1200
|
-26 (-110)
+26 (-110)
|
O 61 (-110)
U 61 (-110)
|
|
|
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
|
–
–
|
+195
-235
|
+6 (-105)
-6 (-115)
|
O 51 (-105)
U 51 (-115)
|
|
|
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
|
–
–
|
-1800
+850
|
-21.5 (-110)
+21.5 (-110)
|
O 51 (-115)
U 51 (-105)
|
|
|
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
|
–
–
|
-410
+305
|
-10.5 (-105)
+10.5 (-115)
|
O 51 (-110)
U 51 (-110)
|
|
|
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
|
–
–
|
-300
+250
|
-7.5 (-105)
+7.5 (-115)
|
O 48 (-110)
U 48 (-110)
|
|
|
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
|
–
–
|
-115
-105
|
-1.5 (-110)
+1.5 (-110)
|
O 59 (-110)
U 59 (-110)
|
|
|
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
|
–
–
|
-210
+175
|
-5.5 (-115)
+5.5 (-105)
|
O 58 (-115)
U 58 (-105)
|
|
|
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
|
–
–
|
+1100
-3300
|
+26 (-110)
-26 (-110)
|
O 53.5 (-105)
U 53.5 (-115)
|
|
|
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
|
–
–
|
+240
-290
|
+7.5 (-115)
-7.5 (-105)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
|
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
|
–
–
|
-450
+335
|
-12 (-110)
+12 (-110)
|
O 58.5 (-110)
U 58.5 (-110)
|
|
|
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
|
–
–
|
-160
+135
|
-3 (-110)
+3 (-110)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
|
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
|
–
–
|
+575
-900
|
+17 (-115)
-17 (-105)
|
O 53 (-110)
U 53 (-110)
|
|
|
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
|
–
–
|
-585
|
-14 (-110)
|
O 61.5 (-115)
U 61.5 (-105)
|
|
|
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
|
–
–
|
+180
-220
|
+5 (-110)
-5 (-110)
|
O 53 (-110)
U 53 (-110)
|
|
|
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
|
–
–
|
+145
-170
|
+3.5 (-115)
-3.5 (-105)
|
O 56 (-110)
U 56 (-110)
|
|
|
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
|
–
–
|
+120
-140
|
+3 (-115)
-3 (-105)
|
O 56 (-105)
U 56 (-115)
|
|
|
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
|
–
–
|
+300
-400
|
+10 (-110)
-10 (-110)
|
O 48.5 (-115)
U 48.5 (-105)
|
|
|
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
|
–
–
|
-420
+315
|
-10.5 (-110)
+10.5 (-110)
|
O 49 (-115)
U 49 (-105)
|
|
|
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
|
–
–
|
+140
-165
|
+3.5 (-115)
-3.5 (-105)
|
O 61.5 (-115)
U 61.5 (-105)
|
|
|
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
|
–
–
|
+275
-350
|
+9.5 (-110)
-9.5 (-110)
|
O 39.5 (-115)
U 39.5 (-105)
|
|
|
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
|
–
–
|
-470
+345
|
-11 (-110)
+11 (-110)
|
O 47 (-115)
U 47 (-105)
|
|
|
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
|
–
–
|
+115
-135
|
+2.5 (+100)
-2.5 (-120)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
|
–
–
|
-210
+175
|
-5 (-110)
+5 (-110)
|
O 54.5 (-115)
U 54.5 (-105)
|
|
|
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
|
–
–
|
+200
-240
|
+6 (-105)
-6 (-115)
|
O 42.5 (-105)
U 42.5 (-115)
|
|
|
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
|
–
–
|
-115
-105
|
-1 (-110)
+1 (-110)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
|
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
|
–
–
|
+410
-585
|
+14 (-110)
-14 (-110)
|
O 62 (-105)
U 62 (-115)
|
|
|
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
|
–
–
|
+155
-180
|
+4 (-110)
-4 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
|
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
|
–
–
|
-750
|
-16 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
|
–
–
|
-145
+125
|
-3 (-105)
+3 (-115)
|
O 47 (-115)
U 47 (-105)
|
|
|
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
|
–
–
|
+120
-140
|
+2.5 (+100)
-2.5 (-120)
|
O 52.5 (-105)
U 52.5 (-115)
|
|
|
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
|
–
–
|
+200
-240
|
+6.5 (-110)
-6.5 (-110)
|
O 55 (-105)
U 55 (-115)
|
|
|
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
|
–
–
|
+100
|
+1.5 (-115)
|
O 40.5 (-115)
U 40.5 (-105)
|
|
|
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
|
–
–
|
+375
|
+13 (-105)
|
O 50.5 (-115)
U 50.5 (-105)
|
|
|
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
|
–
–
|
+4000
-15000
|
+36.5 (-110)
-36.5 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
|
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
|
–
–
|
+155
-180
|
+4 (-115)
-4 (-105)
|
O 67.5 (-110)
U 67.5 (-110)
|
|
|
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
|
–
–
|
-280
+230
|
-7 (-120)
+7 (+100)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
|
–
–
|
-770
+540
|
-16.5 (-115)
+16.5 (-105)
|
O 55.5 (-112)
U 55.5 (-108)
|
|
|
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
|
–
–
|
|
+31.5 (-110)
-31.5 (-110)
|
O 45 (-110)
U 45 (-110)
|
|
|
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
|
–
–
|
+265
-330
|
+8.5 (-110)
-8.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
|
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
|
–
–
|
+2000
-10000
|
+30 (-115)
-30 (-105)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
|
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
|
–
–
|
+100
-120
|
+1.5 (-110)
-1.5 (-110)
|
O 60 (-110)
U 60 (-110)
|
|
|
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
|
–
–
|
-625
+430
|
-14.5 (-105)
+14.5 (-115)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
|
–
–
|
-140
+120
|
-2.5 (-120)
+2.5 (+100)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
|
–
–
|
+1600
-4500
|
+25.5 (-110)
-25.5 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
|
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
|
–
–
|
+170
-200
|
+5 (-110)
-5 (-110)
|
O 47 (-110)
U 47 (-110)
|
|
|
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
|
–
–
|
-320
+260
|
-8 (-110)
+8 (-110)
|
O 55 (-110)
U 55 (-110)
|
|
|
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
|
–
–
|
+235
-285
|
+7 (-105)
-7 (-115)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
|
–
–
|
+410
-585
|
+13.5 (-110)
-13.5 (-110)
|
O 49 (-110)
U 49 (-110)
|
|
|
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
|
–
–
|
-275
+220
|
-7.5 (-102)
+7.5 (-120)
|
O 60.5 (-105)
U 60.5 (-115)
|
|
|
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
|
–
–
|
-192
+158
|
-4.5 (-110)
+4.5 (-110)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
|
Nov 1, 2025 12:00PM EDT
Cincinnati Bearcats
Utah Utes
11/1/25 12PM
CINCY
UTAH
|
–
–
|
|
+5.5 (-110)
-5.5 (-110)
|
|
|
|
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
|
–
–
|
+640
-1000
|
+17.5 (-115)
-17.5 (-105)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
|
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
|
–
–
|
-420
+320
|
-10.5 (-110)
+10.5 (-110)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
|
Nov 1, 2025 12:00PM EDT
Army Black Knights
Air Force Falcons
11/1/25 12PM
ARMY
AF
|
–
–
|
|
-1.5 (-110)
+1.5 (-110)
|
|
|
|
Nov 1, 2025 12:00PM EDT
Navy Midshipmen
North Texas Mean Green
11/1/25 12PM
NAVY
NOTEX
|
–
–
|
|
+4.5 (-110)
-4.5 (-110)
|
|
|
|
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
|
–
–
|
-105
-114
|
+1.5 (-114)
-1.5 (-106)
|
O 53.5 (-112)
U 53.5 (-108)
|
|
|
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
|
–
–
|
+146
-178
|
+3.5 (-110)
-3.5 (-110)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
|
Nov 1, 2025 12:00PM EDT
Georgia Tech Yellow Jackets
NC State Wolfpack
11/1/25 12PM
GATECH
NCST
|
–
–
|
|
-4.5 (-110)
+4.5 (-110)
|
|
|
|
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
|
–
–
|
-295
+235
|
-7.5 (-104)
+7.5 (-118)
|
O 50.5 (-112)
U 50.5 (-108)
|
|
|
Nov 1, 2025 3:30PM EDT
Indiana Hoosiers
Maryland Terrapins
11/1/25 3:30PM
IND
MD
|
–
–
|
|
-17.5 (-110)
+17.5 (-110)
|
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Michigan State Spartans vs. Nebraska Cornhuskers on October 04, 2025 at Tom Osborne Field at Memorial Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
| LEAN | %WIN | UNITS | RESULT | |
|---|---|---|---|---|
| FSU@STNFRD | STNFRD +18 | 56.6% | 6 | WIN |
| WASHST@UVA | WASHST +17.5 | 58.8% | 8 | WIN |
| NEVADA@NMEX | NEVADA +13.5 | 57.8% | 7 | WIN |
| TEXAS@UK | ARCH MANNING UNDER 1.5 PASS TD | 56.1% | 6 | WIN |
| ARMY@TULANE | ARMY +10 | 55.3% | 5 | WIN |
| SJST@UTAHST | SJST +4 | 54.4% | 4 | LOSS |
| LVILLE@MIAMI | LVILLE +12.5 | 56.5% | 6 | WIN |
| LVILLE@MIAMI | CJ DANIELS UNDER 4.5 RECEPTIONS | 54.4 | 4 | LOSS |
| DEL@JAXST | DEL -2.5 | 57.6% | 6 | LOSS |
| UTEP@SAMST | UTEP -2.5 | 53.9% | 3 | WIN |
| FIU@WKY | FIU +10.5 | 54.6% | 4 | WIN |
| ARKST@SALA | ARKST +7.5 | 54.5% | 4 | WIN |
| ARKST@SALA | JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP | 53.3% | 3 | WIN |
| SJST@WYO | SJST -120 | 59.8% | 7 | LOSS |
| UMASS@KENTST | KENTST -135 | 60.2% | 6 | WIN |
| NOILL@EMICH | EMICH +2.5 | 53.9% | 3 | WIN |
| BYU@ARIZ | ARIZ +2.5 | 54.2% | 3 | LOSS |
| OKLA@TEXAS | OKLA +2.5 | 54.7% | 4 | LOSS |
| NMEX@BOISE | NMEX +16.5 | 56.4% | 6 | WIN |
| WAKE@OREGST | WAKE -2.5 | 56.7% | 6 | WIN |
| ULMON@COASTAL | ULMON -2.5 | 56.8% | 6 | LOSS |
| IOWA@WISC | WISC +4 | 54.8% | 4 | LOSS |
| TOLEDO@BGREEN | TOLEDO -10 | 56.3% | 6 | LOSS |
| SFLA@NOTEX | SFLA +2.5 | 54.3% | 4 | WIN |
| FRESNO@COLOST | RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 | 54.4% | 4 | LOSS |
| JAXST@SAMST | SAMST +7.5 | 55.3% | 5 | WIN |
| USM@GAS | GAS +3.5 | 57.4% | 7 | WIN |
| LIB@UTEP | UTEP +2 | 54.5% | 4 | LOSS |
| SALA@TROY | SALA -118 | 55.2% | 4 | LOSS |
| TULSA@MEMP | MEMP -20.5 | 53.8% | 3 | WIN |
| JMAD@GAST | GAST +20.5 | 54.6% | 4 | WIN |
| WAKE@VATECH | VATECH -5.5 | 56.6% | 6 | LOSS |
| UNLV@WYO | WYO +4.5 | 55.5% | 5 | LOSS |
| PSU@UCLA | PSU -24.5 | 56.3% | 6 | LOSS |
| TXSTSM@ARKST | TXSTSM -13 | 56.7% | 6 | LOSS |
| UVA@LVILLE | ISAAC BROWN OVER 70.5 RUSH YDS | 56.6% | 6 | LOSS |
| WVU@BYU | WVU +20.5 | 54.7% | 4 | WIN |
| SAMST@NMEXST | SAMST -1.5 | 54.1% | 3 | LOSS |
| EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
| SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
| BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
| TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
| UK@SC | SC -5.5 | 54.8% | 4 | WIN |
| WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
| JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
| NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
| ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
| TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
| ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
| WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
| TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |