Michigan State vs Nebraska Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 04)

Updated: 2025-09-27T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Michigan State Spartans travel to Lincoln, Nebraska on October 4, 2025 to take on the Cornhuskers in a marquee Big Ten showdown that mixes rebuilding narratives with high-stakes opportunity. Michigan State arrives with more consistency in recent seasons, while Nebraska is attempting to recapture relevance under Coach Matt Rhule, making this a pivotal test for both programs.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 04, 2025

Start Time: 4:00 PM EST​

Venue: Tom Osborne Field at Memorial Stadium​

Cornhuskers Record: (3-1)

Spartans Record: (3-1)

OPENING ODDS

MICHST Moneyline: +330

NEB Moneyline: -429

MICHST Spread: +10.5

NEB Spread: -10.5

Over/Under: 53.5

MICHST
Betting Trends

  • Michigan State’s 2025 campaign has thus far been marked by inconsistency in the betting markets, with the Spartans losing outright to 25 USC and failing to consistently cover large spreads in high-profile games.

NEB
Betting Trends

  • Nebraska enters 2025 with a dominant offensive profile—averaging 43.5 points per game—but their ATS history remains mixed, as large home favorites in the Big Ten have not always delivered clean covers for the Cornhuskers in recent seasons.

MATCHUP TRENDS

  • Oddsmakers have installed Nebraska as a sizable favorite in this matchup, likely in the double-digit range, which raises the classic underdog angle—if Michigan State keeps this close or forces turnovers, bettors may find value in the Spartans. Given Nebraska’s offensive explosiveness and MSU’s volatility in cover performance, the spread may invite sharp money on the underdog side.

MICHST vs. NEB
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: A. Chiles under 31.5 Rushing Yards.

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Michigan State vs Nebraska Prediction & Odds:
Free CFB Betting Insights for 10/4/25

The October 4, 2025 showdown between Michigan State and Nebraska at Memorial Stadium carries weight for both programs as the Spartans try to establish themselves as a credible contender in the Big Ten while the Cornhuskers look to validate their early-season dominance under Matt Rhule and continue building toward relevance on the national stage. Nebraska has started 2025 explosively, averaging 43.5 points per game while giving up just 13.5, numbers that speak to both offensive efficiency and defensive control, and they will enter this contest as decisive favorites thanks to their ability to impose tempo, run the football effectively, and finish drives in the red zone with touchdowns rather than field goals. Michigan State, at 3–1, has shown glimpses of promise but also inconsistency, most notably in their loss to USC where defensive breakdowns and an inability to sustain drives cost them against an elite opponent, and those issues cannot resurface if they expect to keep pace in a hostile environment. The Spartans are led by quarterback Aidan Chiles, whose combination of mobility and arm strength gives them flexibility, but he must avoid turnovers and hit on explosive plays to prevent Nebraska’s defense from keying in on the run game. Nebraska’s defensive front has been outstanding at limiting opponents’ rushing lanes and pressuring quarterbacks, and they will look to force Chiles into third-and-long situations where mistakes become more likely.

On the other side, Nebraska’s balanced offense has been difficult to contain, as their line controls the trenches, their backs produce consistent yardage, and their passing game has been opportunistic enough to punish defenses that overcommit to the run. For Michigan State to compete, they must win the turnover battle, create disruptive plays on defense, and manufacture short fields through special teams or defensive takeaways, because long, sustained drives against Nebraska’s defense will be difficult. The Huskers, conversely, need to play with focus and avoid the complacency that sometimes strikes heavy favorites, ensuring they continue to execute cleanly on third downs and keep Michigan State from gaining confidence in the second half. The spread is expected to heavily favor Nebraska, but as always in conference play, underdogs can hang around if they manage to slow tempo and steal possessions, making this a potential trap game if the Cornhuskers look ahead. Still, the matchup leans strongly in Nebraska’s favor, as their combination of offensive firepower, defensive discipline, and home-field advantage should allow them to control momentum, dictate pace, and wear down a Michigan State team that is still trying to find consistency on both sides of the ball. Ultimately, the outcome will come down to whether Nebraska maintains its sharpness and finishes drives or whether Michigan State can disrupt rhythm, force mistakes, and turn this contest into a grind that stretches into the fourth quarter with the pressure shifting back onto the home team.

Michigan State Spartans CFB Preview

The Michigan State Spartans enter their October 4, 2025 trip to Lincoln knowing they face one of their toughest challenges of the season against a Nebraska team averaging 43.5 points per game and thriving under Matt Rhule, and for MSU the key will be discipline, poise, and finding ways to stretch the game into the fourth quarter while keeping the margin manageable. Michigan State sits at 3–1, showing promise in certain stretches but also vulnerability in their 45–31 loss to USC, where defensive breakdowns and inconsistent execution proved costly, and they cannot afford a similar letdown against a Cornhuskers team with the weapons to punish mistakes immediately. The Spartans’ offense revolves around quarterback Aidan Chiles, whose athleticism and arm talent give them options, but he must play efficiently, avoid turnovers, and use his legs strategically to extend drives and keep Nebraska’s aggressive defensive front from dictating tempo. With injuries and inexperience in the backfield, the ground game will need to be creative, relying on misdirection, play action, and screens to offset Nebraska’s strength in the trenches, and the offensive line must hold up long enough to give Chiles a chance to find receivers downfield.

Defensively, Michigan State must tighten up against the run and be aggressive in creating negative plays early in drives, because if Nebraska controls down-and-distance and opens up its playbook, the Spartans will be fighting uphill all game. Pressure packages and disguised coverages could help disrupt rhythm, but execution must be sharp, and they cannot afford to miss tackles or give up explosive plays in the secondary. Special teams will also be vital, as flipping field position or capitalizing on a momentum-shifting play in returns or coverage could be the difference between a close contest and Nebraska running away with it. From a betting perspective, Michigan State has been inconsistent against the spread, reflecting their volatility, and entering this matchup as a heavy underdog, their challenge is not only competing for a win but also showing enough resilience to stay within the number against a Nebraska team that has shown both offensive balance and defensive toughness. For MSU to succeed, they must lean on grit, play mistake-free football, and make Nebraska earn every yard while hoping their own offense can produce enough explosive plays to keep the Huskers honest. If the Spartans execute cleanly, limit penalties, and turn turnovers into points, they have an outside chance to push Nebraska into uncomfortable territory, but if they allow early momentum to snowball, the night in Lincoln could get away from them quickly.

The Michigan State Spartans travel to Lincoln, Nebraska on October 4, 2025 to take on the Cornhuskers in a marquee Big Ten showdown that mixes rebuilding narratives with high-stakes opportunity. Michigan State arrives with more consistency in recent seasons, while Nebraska is attempting to recapture relevance under Coach Matt Rhule, making this a pivotal test for both programs. Michigan State vs Nebraska AI Prediction: Free CFB Betting Insights for Oct 04. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Nebraska Cornhuskers CFB Preview

The Nebraska Cornhuskers return to Memorial Stadium on October 4, 2025 carrying the momentum of a strong start to the season and the expectation of handling business against a Michigan State team still searching for consistency, and this game provides them a chance to reinforce their identity as one of the Big Ten’s most improved programs under Matt Rhule. Nebraska has been dominant through its first four games, averaging 43.5 points per game while surrendering only 13.5, a balance that highlights both their offensive explosiveness and their ability to clamp down defensively when opponents approach scoring range. Their offense has thrived on balance, with a physical ground attack that sets the tone and opens up opportunities in the passing game, where efficiency and discipline have limited turnovers and produced touchdowns at a high rate, allowing them to build comfortable margins early in games. Their offensive line has been one of their biggest assets, consistently winning trench battles and keeping quarterbacks upright, while the rotation of running backs has provided both power and speed, making them difficult to scheme against.

Defensively, the Huskers have been just as impressive, shutting down rushing lanes, applying relentless pressure up front, and playing disciplined coverage in the secondary, which has forced opponents into mistakes and stalled drives. At home, Nebraska feeds off one of the most passionate fan bases in the country, and the energy at Memorial Stadium has helped create an environment where opponents struggle to communicate and execute, especially on third downs. Against Michigan State, Nebraska’s mission will be to start fast, establish control at the line of scrimmage, and force the Spartans into a one-dimensional passing attack that plays directly into their defensive strength. Special teams, often a key factor in tight conference games, will also need to remain sharp, as avoiding miscues and maintaining strong coverage units will prevent Michigan State from generating the momentum swings they will desperately need as underdogs. From a betting perspective, Nebraska enters as a heavy favorite, and while that places pressure on them to deliver not just a win but also a convincing cover, their combination of offensive firepower and defensive discipline makes them well-positioned to meet those expectations if they execute. The formula for the Cornhuskers is straightforward: dominate the trenches, finish red-zone opportunities with touchdowns, and continue their defensive efficiency by keeping Michigan State from sustaining long drives. If they stick to that blueprint and avoid complacency, Nebraska should not only secure another victory but also deliver a statement performance that further cements their place among the Big Ten’s rising contenders in 2025.

Michigan State vs. Nebraska Prop Picks (AI)

AI algorithm Remi is pouring through mountains of stats on each team. In fact, anytime the Spartans and Cornhuskers play there’s always several intriguing angles to key in on. Not to mention games played at Tom Osborne Field at Memorial Stadium in Oct seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: A. Chiles under 31.5 Rushing Yards.

Michigan State vs. Nebraska Prediction (AI)

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Remi, our AI sports wizard, has been pouring over millions of data from every simulation between the Spartans and Cornhuskers and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.

The Algorithm has been most keyed in on the trending factor knucklehead sportsbettors tend to put on Michigan State’s strength factors between a Spartans team going up against a possibly rested Cornhuskers team. Trends look to say the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Michigan State vs Nebraska picks, computer picks Spartans vs Cornhuskers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/23 SALA@GAST UNLOCK THIS PICK 4 EXECUTIVE Locked EXECUTIVE

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Spartans Betting Trends

Michigan State’s 2025 campaign has thus far been marked by inconsistency in the betting markets, with the Spartans losing outright to 25 USC and failing to consistently cover large spreads in high-profile games.

Cornhuskers Betting Trends

Nebraska enters 2025 with a dominant offensive profile—averaging 43.5 points per game—but their ATS history remains mixed, as large home favorites in the Big Ten have not always delivered clean covers for the Cornhuskers in recent seasons.

Spartans vs. Cornhuskers Matchup Trends

Oddsmakers have installed Nebraska as a sizable favorite in this matchup, likely in the double-digit range, which raises the classic underdog angle—if Michigan State keeps this close or forces turnovers, bettors may find value in the Spartans. Given Nebraska’s offensive explosiveness and MSU’s volatility in cover performance, the spread may invite sharp money on the underdog side.

Michigan State vs. Nebraska Game Info

Michigan State vs Nebraska starts on October 04, 2025 at 4:00 PM EST.

Venue: Tom Osborne Field at Memorial Stadium.

Spread: Nebraska -10.5
Moneyline: Michigan State +330, Nebraska -429
Over/Under: 53.5

Michigan State: (3-1)  |  Nebraska: (3-1)

Remi's searched hard and found the best prop for this matchup: A. Chiles under 31.5 Rushing Yards.. Prices move—always shop for the best number.

Oddsmakers have installed Nebraska as a sizable favorite in this matchup, likely in the double-digit range, which raises the classic underdog angle—if Michigan State keeps this close or forces turnovers, bettors may find value in the Spartans. Given Nebraska’s offensive explosiveness and MSU’s volatility in cover performance, the spread may invite sharp money on the underdog side.

MICHST trend: Michigan State’s 2025 campaign has thus far been marked by inconsistency in the betting markets, with the Spartans losing outright to 25 USC and failing to consistently cover large spreads in high-profile games.

NEB trend: Nebraska enters 2025 with a dominant offensive profile—averaging 43.5 points per game—but their ATS history remains mixed, as large home favorites in the Big Ten have not always delivered clean covers for the Cornhuskers in recent seasons.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Michigan State vs. Nebraska Odds

AI algorithm Remi is pouring through tons of data points on each player. In fact, anytime the Michigan State vs Nebraska trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable patterns.

Michigan State vs Nebraska Opening Odds

MICHST Moneyline: +330
NEB Moneyline: -429
MICHST Spread: +10.5
NEB Spread: -10.5
Over/Under: 53.5

Michigan State vs Nebraska Live Odds

Games PTS ML SPR O/U
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-5000
+1200
-26 (-110)
+26 (-110)
O 61 (-110)
U 61 (-110)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+195
-235
+6 (-105)
-6 (-115)
O 51 (-105)
U 51 (-115)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1800
+850
-21.5 (-110)
+21.5 (-110)
O 51 (-115)
U 51 (-105)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-410
+305
-10.5 (-105)
+10.5 (-115)
O 51 (-110)
U 51 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-300
+250
-7.5 (-105)
+7.5 (-115)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-115
-105
-1.5 (-110)
+1.5 (-110)
O 59 (-110)
U 59 (-110)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-210
+175
-5.5 (-115)
+5.5 (-105)
O 58 (-115)
U 58 (-105)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1100
-3300
+26 (-110)
-26 (-110)
O 53.5 (-105)
U 53.5 (-115)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+240
-290
+7.5 (-115)
-7.5 (-105)
O 44.5 (-110)
U 44.5 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-450
+335
-12 (-110)
+12 (-110)
O 58.5 (-110)
U 58.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-160
+135
-3 (-110)
+3 (-110)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+575
-900
+17 (-115)
-17 (-105)
O 53 (-110)
U 53 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-585
 
-14 (-110)
O 61.5 (-115)
U 61.5 (-105)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+180
-220
+5 (-110)
-5 (-110)
O 53 (-110)
U 53 (-110)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+145
-170
+3.5 (-115)
-3.5 (-105)
O 56 (-110)
U 56 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
+120
-140
+3 (-115)
-3 (-105)
O 56 (-105)
U 56 (-115)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+300
-400
+10 (-110)
-10 (-110)
O 48.5 (-115)
U 48.5 (-105)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-420
+315
-10.5 (-110)
+10.5 (-110)
O 49 (-115)
U 49 (-105)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+140
-165
+3.5 (-115)
-3.5 (-105)
O 61.5 (-115)
U 61.5 (-105)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+275
-350
+9.5 (-110)
-9.5 (-110)
O 39.5 (-115)
U 39.5 (-105)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-470
+345
-11 (-110)
+11 (-110)
O 47 (-115)
U 47 (-105)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+115
-135
+2.5 (+100)
-2.5 (-120)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-210
+175
-5 (-110)
+5 (-110)
O 54.5 (-115)
U 54.5 (-105)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+200
-240
+6 (-105)
-6 (-115)
O 42.5 (-105)
U 42.5 (-115)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-115
-105
-1 (-110)
+1 (-110)
O 45.5 (-110)
U 45.5 (-110)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+410
-585
+14 (-110)
-14 (-110)
O 62 (-105)
U 62 (-115)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+155
-180
+4 (-110)
-4 (-110)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-750
 
-16 (-110)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-145
+125
-3 (-105)
+3 (-115)
O 47 (-115)
U 47 (-105)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+120
-140
+2.5 (+100)
-2.5 (-120)
O 52.5 (-105)
U 52.5 (-115)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+200
-240
+6.5 (-110)
-6.5 (-110)
O 55 (-105)
U 55 (-115)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+100
 
+1.5 (-115)
 
O 40.5 (-115)
U 40.5 (-105)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+375
 
+13 (-105)
 
O 50.5 (-115)
U 50.5 (-105)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+4000
-15000
+36.5 (-110)
-36.5 (-110)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+155
-180
+4 (-115)
-4 (-105)
O 67.5 (-110)
U 67.5 (-110)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-280
+230
-7 (-120)
+7 (+100)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-770
+540
-16.5 (-115)
+16.5 (-105)
O 55.5 (-112)
U 55.5 (-108)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+31.5 (-110)
-31.5 (-110)
O 45 (-110)
U 45 (-110)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+265
-330
+8.5 (-110)
-8.5 (-110)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+2000
-10000
+30 (-115)
-30 (-105)
O 45.5 (-110)
U 45.5 (-110)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 60 (-110)
U 60 (-110)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-625
+430
-14.5 (-105)
+14.5 (-115)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-140
+120
-2.5 (-120)
+2.5 (+100)
O 49.5 (-110)
U 49.5 (-110)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1600
-4500
+25.5 (-110)
-25.5 (-110)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+170
-200
+5 (-110)
-5 (-110)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-320
+260
-8 (-110)
+8 (-110)
O 55 (-110)
U 55 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+235
-285
+7 (-105)
-7 (-115)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+410
-585
+13.5 (-110)
-13.5 (-110)
O 49 (-110)
U 49 (-110)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-102)
+7.5 (-120)
O 60.5 (-105)
U 60.5 (-115)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-192
+158
-4.5 (-110)
+4.5 (-110)
O 53.5 (-110)
U 53.5 (-110)
Nov 1, 2025 12:00PM EDT
Cincinnati Bearcats
Utah Utes
11/1/25 12PM
CINCY
UTAH
 
 
+5.5 (-110)
-5.5 (-110)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+640
-1000
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-420
+320
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Army Black Knights
Air Force Falcons
11/1/25 12PM
ARMY
AF
 
 
-1.5 (-110)
+1.5 (-110)
Nov 1, 2025 12:00PM EDT
Navy Midshipmen
North Texas Mean Green
11/1/25 12PM
NAVY
NOTEX
 
 
+4.5 (-110)
-4.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+146
-178
+3.5 (-110)
-3.5 (-110)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 12:00PM EDT
Georgia Tech Yellow Jackets
NC State Wolfpack
11/1/25 12PM
GATECH
NCST
 
 
-4.5 (-110)
+4.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-295
+235
-7.5 (-104)
+7.5 (-118)
O 50.5 (-112)
U 50.5 (-108)
Nov 1, 2025 3:30PM EDT
Indiana Hoosiers
Maryland Terrapins
11/1/25 3:30PM
IND
MD
 
 
-17.5 (-110)
+17.5 (-110)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Michigan State Spartans vs. Nebraska Cornhuskers on October 04, 2025 at Tom Osborne Field at Memorial Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN