Illinois vs Purdue Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 04)

Updated: 2025-09-27T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Illinois Fighting Illini head to Ross-Ade Stadium on October 4, 2025 to face the Purdue Boilermakers in a Big Ten matchup that could carry outsized impact for both programs’ trajectories. Illinois enters off a dramatic road win over USC and is being installed as a road favorite, while Purdue tries to defend home turf under offensive and defensive pressure.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 04, 2025

Start Time: 12:00 PM EST​

Venue: Ross-Ade Stadium​

Boilermakers Record: (2-2)

Fighting Illini Record: (4-1)

OPENING ODDS

ILL Moneyline: -353

PURDUE Moneyline: +276

ILL Spread: -9.5

PURDUE Spread: +9.5

Over/Under: 55.5

ILL
Betting Trends

  • Illinois has shown strong ATS performance in 2025, covering in 3 of its first 4 games (a 75 % cover rate) and posting an ATS plus/minus of about –2.8 in margin statistics.

PURDUE
Betting Trends

  • Purdue has been more middling in ATS outcomes this season, generally splitting their games and showing less consistency in covering lines at home or overall.

MATCHUP TRENDS

  • Illinois was opened as about a 10.5-point road favorite in this matchup according to FanDuel odds, a telling line given road favorites of that margin are scrutinized heavily. The line movement and public betting behavior will be worth watching, especially because Purdue’s motivation to defend home turf (especially before a tough upcoming schedule) could give extra edge to home bettors.

ILL vs. PURDUE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: N. Tuggle under 42.5 Receiving Yards.

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Illinois vs Purdue Prediction & Odds:
Free CFB Betting Insights for 10/4/25

The October 4, 2025 matchup between Illinois and Purdue at Ross-Ade Stadium is a compelling Big Ten clash that highlights two teams moving in different directions, with Illinois riding the momentum of a breakthrough road win over USC while Purdue looks to find stability under a coaching staff still working to establish consistency. Illinois has impressed early in the season with a 3–1 record, averaging more than 36 points per game while showing balance on both sides of the ball, and their ability to score in bunches gives them a dangerous profile when they can dictate tempo. The Illini’s offensive line has been sturdy, giving their quarterback time to distribute to multiple targets, while the running game has provided enough push to keep defenses from overcommitting to coverage, and that balance has made their red-zone efficiency one of the key drivers of their early success. On defense, Illinois has allowed just over 21 points per contest, which is respectable given the quality of competition, and they’ve been opportunistic at key moments with third-down stops and timely takeaways. Purdue, on the other hand, enters at 2–2 and has been more erratic, averaging about 28 points per game while conceding 26, numbers that highlight both offensive potential and defensive inconsistency.

Their quarterback play has shown flashes of explosiveness, but too often the Boilermakers have stalled in the red zone or been undone by turnovers, and those issues cannot continue against an Illinois team capable of punishing mistakes quickly. The battle in the trenches will be decisive, as Illinois’s defensive front will look to collapse pockets and force hurried throws, while Purdue must establish a running game to keep Illinois honest and buy their quarterback time to find mismatches downfield. For Illinois, the path to victory lies in maintaining composure on the road, avoiding costly turnovers, and capitalizing on Purdue’s defensive lapses, while the Boilermakers will need to start fast, leverage crowd energy, and create disruptive plays to keep the Illini from finding rhythm. Special teams could also loom large, as both sides will look to gain field position edges in a matchup where one or two big plays may tilt the balance. From a betting perspective, Illinois has been reliable against the spread so far this season, covering in three of four contests, while Purdue has been inconsistent, making this game another test of whether Illinois can maintain sharpness as a road favorite. Ultimately, this contest feels like a test of focus and execution: Illinois has the talent and momentum to win convincingly, but Purdue has enough firepower and home-field advantage to make things interesting if the Illini slip, making this an underrated but potentially pivotal Big Ten game.

Illinois Fighting Illini CFB Preview

The Illinois Fighting Illini head into their October 4, 2025 matchup at Purdue as road favorites, riding the confidence of a 3–1 start to the season and a signature victory over USC that has elevated expectations for Bret Bielema’s team and given them a chance to prove they can handle business in Big Ten play against an opponent that will be desperate to protect its home field, and the Illini will know that consistency, composure, and execution will be the keys to extending their momentum. Offensively, Illinois has been one of the more balanced units in the conference, averaging over 36 points per game with an attack that blends physicality in the running game with a quarterback who has demonstrated both poise and accuracy in distributing the football, and this versatility allows them to sustain drives, control tempo, and stress defenses vertically while still grinding out yards on the ground. The offensive line has been a stabilizing force, creating lanes for backs to push forward for tough yardage while also keeping pressure away from the quarterback, and when Illinois establishes balance early they have been difficult to slow down, as evidenced by their efficiency in the red zone where they have consistently turned trips inside the 20 into touchdowns rather than settling for field goals. Their passing game has benefitted from a corps of receivers who can create separation, attack downfield, and punish secondaries that try to load the box, and their ability to hit explosive plays has been one of the key drivers of their offensive surge, making them a dangerous opponent regardless of down and distance.

On defense, Illinois has allowed just over 21 points per contest, which places them in the middle of the pack statistically but belies how tough they have been in situational moments, with their front seven generating steady pressure and their secondary coming up with timely turnovers and breakups when games have hung in the balance. That ability to make key stops on third downs and force opponents to settle for field goals has given their offense the breathing room needed to play confidently, and that formula will be crucial against a Purdue team that has the ability to strike quickly if given space to operate. Special teams discipline has also played a role in Illinois’s early success, as their kicking game has been consistent and their coverage units have minimized explosive returns, something they will need to continue to ensure Purdue does not gain momentum through hidden yardage. As a road favorite, Illinois will be challenged not just physically but mentally, as they must tune out the noise of a Big Ten environment and avoid mistakes that can quickly swing games against underdog opponents, but their track record so far in 2025 suggests they have the poise and maturity to manage that pressure. Against Purdue, their mission will be to start quickly, establish their physicality at the line of scrimmage, and avoid giving the Boilermakers belief that they can pull an upset, because if Illinois can build an early lead their balance and discipline should allow them to keep Purdue at bay for four quarters. From a betting perspective, Illinois has covered in three of their first four games, a strong sign that they have consistently outperformed market expectations, and that trend could continue if they bring their usual sharpness to West Lafayette. Ultimately, Illinois arrives with momentum, depth, and balance on both sides of the ball, and if they play to their standard by protecting the football, maintaining their efficiency in the red zone, and leaning on their defense to generate disruptive plays, they should be able to leave Purdue with both a win and validation that they are a serious factor in the Big Ten West race.

The Illinois Fighting Illini head to Ross-Ade Stadium on October 4, 2025 to face the Purdue Boilermakers in a Big Ten matchup that could carry outsized impact for both programs’ trajectories. Illinois enters off a dramatic road win over USC and is being installed as a road favorite, while Purdue tries to defend home turf under offensive and defensive pressure. Illinois vs Purdue AI Prediction: Free CFB Betting Insights for Oct 04. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Purdue Boilermakers CFB Preview

The Purdue Boilermakers enter their October 4, 2025 clash with Illinois at Ross-Ade Stadium looking to flip the script on what has been an inconsistent start to the season, and their mission will be to defend home turf against an Illini team riding high off a signature win and showing signs of offensive balance and defensive toughness that make them a legitimate Big Ten threat, which places added pressure on Purdue to execute cleanly and avoid the kind of mistakes that have hampered them in their first four games. Purdue sits at 2–2 on the season, averaging just under 28 points per game while surrendering 26, numbers that suggest they can be competitive but also highlight the defensive lapses and offensive inefficiency that have cost them against stronger opponents, and those trends must be corrected if they hope to slow down Illinois. Their offense, under Barry Odom’s guidance, has shown flashes of explosiveness, with quarterback Ryan Browne capable of delivering big plays when protected, but too often drives have stalled due to pressure, turnovers, or red-zone inefficiency, and the Boilermakers must find ways to finish possessions with touchdowns instead of field goals to keep pace with an Illinois team that thrives on converting opportunities. The offensive line, a group that has struggled to consistently win battles in the trenches, will be under scrutiny as it faces an Illinois front seven that has made a living disrupting timing and collapsing pockets, and Purdue’s ability to establish the run early will go a long way toward alleviating pressure on Browne and preventing the Illini from dictating tempo.

On defense, the Boilermakers have been inconsistent, showing an ability to generate pressure and make stops in spurts but also giving up chunk plays that have swung momentum, and against Illinois’s balanced attack they must focus on maintaining gap discipline, keeping leverage on the outside, and forcing the Illini into longer down-and-distance scenarios where mistakes are more likely. Turnovers will be especially critical for Purdue, as stealing possessions and giving their offense short fields could provide the spark needed to hang around in a game where they enter as underdogs, and their defensive backs will need to stay disciplined against Illinois’s receivers, who have proven capable of breaking games open with vertical shots. Special teams could also provide a path for Purdue to gain an edge, whether through flipping field position, hitting a big return, or blocking a kick, as momentum swings in this phase may prove critical in front of their home crowd. The energy of Ross-Ade Stadium will be an asset, as the fans will look to rattle Illinois’s offense and give the Boilermakers a boost on crucial downs, but Purdue must reward that support by playing with urgency, avoiding penalties, and showing resilience in high-leverage moments. From a betting standpoint, Purdue has been less consistent than Illinois against the spread, but home underdogs in conference play often carry contrarian value if they can hang around into the second half, and that will be the task here—stay within striking distance, force Illinois to grind out possessions, and use the crowd to generate a late push. Ultimately, Purdue’s path to success lies in playing their most complete game of the season, as they will need to tighten up defensively, capitalize on every offensive opportunity, and lean on home-field advantage to keep Illinois from imposing its will, and if they can do that, they could turn what looks like a difficult matchup on paper into one of the more surprising outcomes of the Big Ten weekend.

Illinois vs. Purdue Prop Picks (AI)

Remi is pouring through loads of data on each team. In fact, anytime the Fighting Illini and Boilermakers play there’s always several intriguing angles to key in on. Not to mention games played at Ross-Ade Stadium in Oct rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: N. Tuggle under 42.5 Receiving Yards.

Illinois vs. Purdue Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every facet between the Fighting Illini and Boilermakers and using recursive machine learning and cutting-edge AI to boil down the data to a single cover probability.

The Algorithm has been most fixated on the growing weight human bettors often put on Purdue’s strength factors between a Fighting Illini team going up against a possibly healthy Boilermakers team. Trends look to say the true game analytics might reflect a slight lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Illinois vs Purdue picks, computer picks Fighting Illini vs Boilermakers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Fighting Illini Betting Trends

Illinois has shown strong ATS performance in 2025, covering in 3 of its first 4 games (a 75 % cover rate) and posting an ATS plus/minus of about –2.8 in margin statistics.

Boilermakers Betting Trends

Purdue has been more middling in ATS outcomes this season, generally splitting their games and showing less consistency in covering lines at home or overall.

Fighting Illini vs. Boilermakers Matchup Trends

Illinois was opened as about a 10.5-point road favorite in this matchup according to FanDuel odds, a telling line given road favorites of that margin are scrutinized heavily. The line movement and public betting behavior will be worth watching, especially because Purdue’s motivation to defend home turf (especially before a tough upcoming schedule) could give extra edge to home bettors.

Illinois vs. Purdue Game Info

Illinois vs Purdue starts on October 04, 2025 at 12:00 PM EST.

Spread: Purdue +9.5
Moneyline: Illinois -353, Purdue +276
Over/Under: 55.5

Illinois: (4-1)  |  Purdue: (2-2)

Remi's searched hard and found the best prop for this matchup: N. Tuggle under 42.5 Receiving Yards.. Prices move—always shop for the best number.

Illinois was opened as about a 10.5-point road favorite in this matchup according to FanDuel odds, a telling line given road favorites of that margin are scrutinized heavily. The line movement and public betting behavior will be worth watching, especially because Purdue’s motivation to defend home turf (especially before a tough upcoming schedule) could give extra edge to home bettors.

ILL trend: Illinois has shown strong ATS performance in 2025, covering in 3 of its first 4 games (a 75 % cover rate) and posting an ATS plus/minus of about –2.8 in margin statistics.

PURDUE trend: Purdue has been more middling in ATS outcomes this season, generally splitting their games and showing less consistency in covering lines at home or overall.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Illinois vs. Purdue Odds

AI algorithm Remi is pouring through loads of data points on each team. In fact, anytime the Illinois vs Purdue trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments rarely follow normal, predictable patterns.

Illinois vs Purdue Opening Odds

ILL Moneyline: -353
PURDUE Moneyline: +276
ILL Spread: -9.5
PURDUE Spread: +9.5
Over/Under: 55.5

Illinois vs Purdue Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-360
 
-9.5 (-105)
O 55 (-118)
U 55 (-107)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-115
-105
-1 (-110)
+1 (-110)
O 51 (-110)
U 51 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-240
+185
-6.5 (-112)
+6.5 (-109)
O 56 (-110)
U 56 (-112)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4500
+1550
-26.5 (-110)
+26.5 (-110)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+160
-205
+4.5 (-110)
-4.5 (-110)
O 50 (-112)
U 50 (-110)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1700
+950
-21.5 (-110)
+21.5 (-110)
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-400
+310
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-305
+240
-7.5 (-105)
+7.5 (-115)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+115
-2.5 (-110)
+2.5 (-110)
O 58.5 (-110)
U 58.5 (-110)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-210
+175
-5 (-110)
+5 (-110)
O 63.5 (-110)
U 63.5 (-110)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1200
-5000
+25.5 (-113)
-25.5 (-108)
O 54.5 (-115)
U 54.5 (-106)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+228
-285
+7 (-110)
-7 (-110)
O 43 (-110)
U 43 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-480
+360
-12.5 (-110)
+12.5 (-110)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-175
+148
-3.5 (-110)
+3.5 (-110)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+600
-1000
+17.5 (-112)
-17.5 (-109)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-600
 
-14.5 (-110)
O 63 (-110)
U 63 (-110)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+180
-220
+5 (-110)
-5 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-155
+3 (-110)
-3 (-110)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
+100
-120
+1 (-110)
-1 (-110)
O 57 (-110)
U 57 (-110)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+285
-365
+9.5 (-110)
-9.5 (-110)
O 48 (-115)
U 48 (-105)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-420
+320
-10.5 (-115)
+10.5 (-105)
O 49 (-110)
U 49 (-110)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-110)
-3 (-110)
O 61.5 (-110)
U 61.5 (-110)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+270
-345
+8.5 (-110)
-8.5 (-110)
O 39 (-110)
U 39 (-110)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-480
+360
-12 (-110)
+12 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+120
-152
+2.5 (-105)
-2.5 (-117)
O 48.5 (-115)
U 48.5 (-106)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-225
+185
-6 (-110)
+6 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+175
-210
+5.5 (-110)
-5.5 (-110)
O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-105
-115
+1 (-110)
-1 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+475
-750
+15.5 (-110)
-15.5 (-110)
O 62.5 (-113)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+162
-195
+4.5 (-110)
-4.5 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-800
 
-16.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-155
+130
-3 (-110)
+3 (-110)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+118
-140
+2.5 (-110)
-2.5 (-110)
O 52.5 (-105)
U 52.5 (-115)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+200
-260
+6.5 (-107)
-6.5 (-114)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+105
 
+1.5 (-110)
 
O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+335
 
+11 (-110)
 
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+2800
-10000
+38.5 (-114)
-38.5 (-107)
O 56.5 (-110)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+162
-195
+4.5 (-110)
-4.5 (-110)
O 67.5 (-110)
U 67.5 (-110)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-267
+215
-7 (-105)
+7 (-115)
O 44.5 (-115)
U 44.5 (-105)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-750
+450
-15.5 (-110)
+15.5 (-110)
O 55.5 (-107)
U 55.5 (-114)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-110)
-33.5 (-110)
O 44.5 (-110)
U 44.5 (-110)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+270
-345
+9.5 (-110)
-9.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30 (-109)
-30 (-112)
O 45.5 (-112)
U 45.5 (-109)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 62.5 (-110)
U 62.5 (-110)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-650
+460
-14.5 (-115)
+14.5 (-105)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-145
+122
-2.5 (-115)
+2.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1350
-3500
+25.5 (-110)
-25.5 (-110)
O 55 (-110)
U 55 (-110)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+185
-225
+5.5 (-110)
-5.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-360
+275
-9.5 (-107)
+9.5 (-114)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+235
-310
+7.5 (-115)
-7.5 (-107)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+400
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Illinois Fighting Illini vs. Purdue Boilermakers on October 04, 2025 at Ross-Ade Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN