Eastern Michigan vs Buffalo Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 04)

Updated: 2025-09-27T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

Eastern Michigan journeys to Buffalo on October 4, 2025 seeking to reverse a disappointing start to their season, while the Bulls return home riding the expectation of regaining control and defending their turf. The matchup pits a Michigan-based MAC team that has given up nearly 40 points per game against a Buffalo squad trying to build momentum in Conference USA play.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Oct 04, 2025

Start Time: 3:30 PM EST​

Venue: UB Stadium​

Bulls Record: (2-3)

Eagles Record: (1-4)

OPENING ODDS

EMICH Moneyline: +277

BUFF Moneyline: -352

EMICH Spread: +9.5

BUFF Spread: -9.5

Over/Under: 49.5

EMICH
Betting Trends

  • Eastern Michigan is 1–3 overall, scoring 26.8 points per game while allowing 39.8, a negative margin that suggests they’ve struggled to stay within spreads when defensive lapses worsen.

BUFF
Betting Trends

  • Buffalo has had mixed outcomes early, and their offensive inconsistencies and turnover issues have made them volatile in covering at home.

MATCHUP TRENDS

  • Eastern Michigan ranks among the worst in points allowed per game nationally, which means Buffalo has a path to runaway scores if their offense locks in. Also, EMU’s offense has produced 6.02 yards per play, but their defense gives up 7.54 yards per play—those gaps could make this matchup swingy.

EMICH vs. BUFF
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup, but hasn't found a good Prop Bet yet for this game.

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Eastern Michigan vs Buffalo Prediction & Odds:
Free CFB Betting Insights for 10/4/25

The October 4, 2025 MAC showdown between Eastern Michigan and Buffalo has the feel of a pivotal contest for both teams as they try to establish themselves in the conference, with the Eagles coming in at 1–3 and reeling from defensive issues while the Bulls aim to capitalize on their home environment to gain traction in the standings. Eastern Michigan’s season to date has been defined by inconsistency, as their offense has managed a respectable 26.8 points per game and averaged 6.02 yards per play, but their defense has been one of the worst in the nation, giving up 39.8 points per game and allowing 7.54 yards per play, numbers that make it nearly impossible to stay competitive over four quarters. Their rushing game has shown flashes with 579 yards on 124 carries at 4.67 yards per attempt, and their passing game has generated 993 yards and 5 touchdowns with only 2 interceptions, proving that they have playmakers who can stress a defense if given time. The problem has been keeping pace when opponents capitalize on their porous defense, as they are often forced into shootouts that they lack the consistency to win. Buffalo, meanwhile, has had its own struggles but is in a position to take advantage of EMU’s defensive weaknesses, particularly if their offense can start quickly and force the Eagles to chase the game.

The Bulls must improve on their offensive execution, cutting down turnovers and finishing drives, but against a defense as vulnerable as EMU’s, opportunities will be there. Defensively, Buffalo will focus on containing the run and not allowing Eastern Michigan to establish balance, as forcing the Eagles into predictable passing situations could lead to pressure and mistakes. Special teams will also play a critical role, as both squads have shown inconsistency in coverage and returns, and a single big play in this area could flip momentum in what might otherwise be a close contest. For Eastern Michigan, the path to victory lies in protecting the football, controlling tempo with their run game, and making enough defensive stops to give their offense a chance, while Buffalo’s route is to exploit EMU’s defensive lapses, lean on the energy of their home crowd, and play mistake-free football. From a betting perspective, Eastern Michigan’s defensive inefficiency makes them hard to trust even as an underdog, but their ability to generate explosive plays means they cannot be counted out entirely, while Buffalo’s steadier profile at home suggests they may be better positioned to cover if they can avoid the inconsistency that has dogged them. Ultimately, this matchup should come down to which team performs better in situational football—third downs, red-zone efficiency, and turnovers—and the side that executes more cleanly in those critical moments will likely walk away with an important MAC victory.

Eastern Michigan Eagles CFB Preview

The Eastern Michigan Eagles step into their October 4, 2025 road trip to Buffalo knowing their season is already at a crossroads, as a 1–3 start has exposed major defensive flaws that must be corrected quickly if they want to compete in the MAC. Through four games, the Eagles have allowed 39.8 points per contest, one of the worst marks in the nation, while opponents have gashed them for 7.54 yards per play, putting tremendous pressure on their offense to keep up in high-scoring environments. That said, their offense has shown enough to inspire belief they can stay competitive, averaging 26.8 points per game and 6.02 yards per play, with the ground attack producing 579 yards on 124 carries at 4.67 yards per rush, and the passing game adding 993 yards with 5 touchdowns and only 2 interceptions. Quarterback play has been a relative strength, as efficiency has limited turnovers, but the Eagles too often find themselves needing to push the pace to compensate for defensive breakdowns, which increases risk and leaves them vulnerable to momentum swings. On third downs, Eastern Michigan has been inconsistent, leading to stalled drives that expose their defense even further, and their red-zone conversion rate has been far from automatic, adding to their frustrations in finishing possessions. Against Buffalo, their offensive line will need to assert itself in the trenches, not only to create running lanes but also to protect long enough for their quarterback to hit playmakers downfield and keep the Bulls’ defense stretched.

Defensively, Eastern Michigan must simplify, focus on tackling fundamentals, and prioritize preventing explosive plays, forcing Buffalo into long drives rather than quick scores, as their current numbers show they cannot survive another game allowing big chunks of yardage. The front seven must win battles at the line of scrimmage, while the secondary must remain disciplined to avoid giving up back-breaking plays that energize Buffalo’s home crowd. Special teams execution will also be critical, as flipping field position or avoiding costly miscues could keep them in striking distance. From a betting perspective, the Eagles’ high-powered offense and explosive play ability make them dangerous underdogs if they can cut down defensive lapses and stay within a possession deep into the second half, but their defensive profile makes them volatile and difficult to back with confidence. For Eastern Michigan to succeed, the formula is simple but demanding: run the ball to control tempo, limit turnovers, improve situational football on third downs and in the red zone, and tighten defensively enough to keep Buffalo from pulling away. If they can deliver their most disciplined and balanced performance of the year, the Eagles have the firepower to make this game competitive and perhaps even steal a much-needed road win.

Eastern Michigan journeys to Buffalo on October 4, 2025 seeking to reverse a disappointing start to their season, while the Bulls return home riding the expectation of regaining control and defending their turf. The matchup pits a Michigan-based MAC team that has given up nearly 40 points per game against a Buffalo squad trying to build momentum in Conference USA play. Eastern Michigan vs Buffalo AI Prediction: Free CFB Betting Insights for Oct 04. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Buffalo Bulls CFB Preview

The Buffalo Bulls return home on October 4, 2025 to host Eastern Michigan with the clear objective of capitalizing on the Eagles’ defensive shortcomings and seizing momentum in a MAC season where they have shown inconsistency but flashes of potential. Buffalo’s season so far has been defined by uneven offensive play and turnover issues that have cost them in winnable situations, yet facing an opponent allowing nearly 40 points per game and 7.54 yards per play presents a prime opportunity for the Bulls to get their offense rolling in front of their home crowd. Their game plan must emphasize balance, leaning on the running game to control tempo while creating play-action opportunities that stretch Eastern Michigan’s secondary, which has struggled with coverage discipline and tackling in space. The Bulls’ quarterback will need to protect the football and deliver sustained drives, avoiding the turnovers that have repeatedly short-circuited their momentum, and their offensive line must set the tone early by winning battles at the line of scrimmage. Defensively, Buffalo will be tested by an Eastern Michigan offense that has been effective when given rhythm, producing 6.02 yards per play and finding success both on the ground at 4.67 yards per carry and through the air with nearly 1,000 passing yards already, and it will be crucial for the Bulls to stay disciplined in containing both elements.

Their front seven must focus on disrupting the run early to force Eastern Michigan into predictable passing downs, where pressure can create mistakes, while the secondary must avoid giving up explosive plays that could negate defensive progress. Third-down defense will be especially critical, as forcing the Eagles into stalled drives not only prevents points but keeps Buffalo’s defense fresh and gives their offense additional opportunities. Special teams could serve as a deciding factor, as Buffalo must avoid coverage breakdowns and seize chances to gain field position, whether through returns or pinning Eastern Michigan deep in their own territory. The energy of playing at home should also give Buffalo an edge in critical moments, particularly if they can build an early lead and put the Eagles in a position where they must abandon balance and chase points. From a betting perspective, Buffalo’s inconsistency makes them a risky favorite, but given Eastern Michigan’s porous defense, the Bulls have a strong case to cover if they execute cleanly on offense and limit turnovers. Ultimately, the Bulls’ formula for success is straightforward: impose their will physically on offense, take advantage of Eastern Michigan’s defensive inefficiency, play disciplined defense to limit explosive plays, and lean on the energy of their home environment to close out a critical MAC victory.

Eastern Michigan vs. Buffalo Prop Picks (AI)

AI algorithm Remi is pouring through mountains of datapoints on each team. In fact, anytime the Eagles and Bulls play there’s always several intriguing angles to key in on. Not to mention games played at UB Stadium in Oct rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup, but hasn't found a good Prop Bet yet for this game.

Eastern Michigan vs. Buffalo Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over tons of data from every angle between the Eagles and Bulls and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.

The Algorithm has been most watching on the linear correlation of weight knucklehead sportsbettors often put on Buffalo’s strength factors between a Eagles team going up against a possibly improved Bulls team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Eastern Michigan vs Buffalo picks, computer picks Eagles vs Bulls, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Eagles Betting Trends

Eastern Michigan is 1–3 overall, scoring 26.8 points per game while allowing 39.8, a negative margin that suggests they’ve struggled to stay within spreads when defensive lapses worsen.

Bulls Betting Trends

Buffalo has had mixed outcomes early, and their offensive inconsistencies and turnover issues have made them volatile in covering at home.

Eagles vs. Bulls Matchup Trends

Eastern Michigan ranks among the worst in points allowed per game nationally, which means Buffalo has a path to runaway scores if their offense locks in. Also, EMU’s offense has produced 6.02 yards per play, but their defense gives up 7.54 yards per play—those gaps could make this matchup swingy.

Eastern Michigan vs. Buffalo Game Info

Eastern Michigan vs Buffalo starts on October 04, 2025 at 3:30 PM EST.

Spread: Buffalo -9.5
Moneyline: Eastern Michigan +277, Buffalo -352
Over/Under: 49.5

Eastern Michigan: (1-4)  |  Buffalo: (2-3)

Remi's searched hard and found the best prop for this matchup, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.

Eastern Michigan ranks among the worst in points allowed per game nationally, which means Buffalo has a path to runaway scores if their offense locks in. Also, EMU’s offense has produced 6.02 yards per play, but their defense gives up 7.54 yards per play—those gaps could make this matchup swingy.

EMICH trend: Eastern Michigan is 1–3 overall, scoring 26.8 points per game while allowing 39.8, a negative margin that suggests they’ve struggled to stay within spreads when defensive lapses worsen.

BUFF trend: Buffalo has had mixed outcomes early, and their offensive inconsistencies and turnover issues have made them volatile in covering at home.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Eastern Michigan vs. Buffalo Odds

AI algorithm Remi is pouring through mountains of stats on each player. In fact, anytime the Eastern Michigan vs Buffalo trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable patterns.

Eastern Michigan vs Buffalo Opening Odds

EMICH Moneyline: +277
BUFF Moneyline: -352
EMICH Spread: +9.5
BUFF Spread: -9.5
Over/Under: 49.5

Eastern Michigan vs Buffalo Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-370
 
-9.5 (-110)
O 55.5 (-110)
U 55.5 (-110)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-108
-108
-1.5 (-105)
+1.5 (-115)
O 51.5 (-110)
U 51.5 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-225
+185
-6.5 (-110)
+6.5 (-110)
O 55.5 (-112)
U 55.5 (-108)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4000
+1600
-26.5 (-112)
+26.5 (-108)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+164
-198
+4.5 (-108)
-4.5 (-112)
O 49.5 (-115)
U 49.5 (-105)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1800
+1000
-21 (-115)
+21 (-105)
O 50.5 (-112)
U 50.5 (-108)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-395
+310
-10.5 (-108)
+10.5 (-112)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-290
+235
-7.5 (-105)
+7.5 (-115)
O 48.5 (-108)
U 48.5 (-112)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+114
-2.5 (-115)
+2.5 (-105)
O 58.5 (-112)
U 58.5 (-108)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-205
+170
-4.5 (-112)
+4.5 (-108)
O 63.5 (-108)
U 63.5 (-112)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1400
-3200
+25.5 (-110)
-25.5 (-110)
O 54.5 (-115)
U 54.5 (-105)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+230
-285
+7 (-105)
-7 (-115)
O 43.5 (-110)
U 43.5 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-500
+380
-12.5 (-108)
+12.5 (-112)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-180
+150
-3.5 (-108)
+3.5 (-112)
O 53.5 (-115)
U 53.5 (-105)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+600
-900
+17.5 (-110)
-17.5 (-110)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-625
 
-14.5 (-108)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+180
-218
+4.5 (-105)
-4.5 (-115)
O 54.5 (-108)
U 54.5 (-112)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-155
+3 (-112)
-3 (-108)
O 56.5 (-115)
U 56.5 (-105)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
-105
-115
+1.5 (-115)
-1.5 (-105)
O 56.5 (-112)
U 56.5 (-108)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+310
-395
+9.5 (-110)
-9.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-410
+320
-10.5 (-110)
+10.5 (-110)
O 49.5 (-105)
U 49.5 (-115)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-112)
-3 (-108)
O 61.5 (-112)
U 61.5 (-108)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+275
-345
+9.5 (-112)
-9.5 (-108)
O 39.5 (-108)
U 39.5 (-112)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-485
+370
-12.5 (-110)
+12.5 (-110)
O 47.5 (-108)
U 47.5 (-112)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+124
-148
+2.5 (-102)
-2.5 (-118)
O 48.5 (-112)
U 48.5 (-108)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-238
+195
-6 (-112)
+6 (-108)
O 53.5 (-112)
U 53.5 (-108)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+180
-218
+5.5 (-112)
-5.5 (-108)
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-102
-118
+1.5 (-115)
-1.5 (-105)
O 46.5 (-108)
U 46.5 (-112)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+455
-625
+15.5 (-108)
-15.5 (-112)
O 62.5 (-112)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+164
-198
+4.5 (-110)
-4.5 (-110)
O 53.5 (-115)
U 53.5 (-105)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-700
 
-16.5 (-108)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-155
+130
-3 (-110)
+3 (-110)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+114
-135
+2.5 (-110)
-2.5 (-110)
O 51.5 (-115)
U 51.5 (-105)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+205
-250
+6.5 (-108)
-6.5 (-112)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+102
 
+1.5 (-110)
 
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+340
 
+10.5 (-105)
 
O 50.5 (-112)
U 50.5 (-108)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+2800
-10000
+38.5 (-115)
-38.5 (-105)
O 56.5 (-108)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+154
-185
+4.5 (-110)
-4.5 (-110)
O 66.5 (-115)
U 66.5 (-105)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-270
+220
-7 (-105)
+7 (-115)
O 44.5 (-115)
U 44.5 (-105)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-650
+470
-15.5 (-110)
+15.5 (-110)
O 54.5 (-118)
U 54.5 (-102)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-108)
-33.5 (-112)
O 44.5 (-112)
U 44.5 (-108)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+280
-355
+8.5 (-108)
-8.5 (-112)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30.5 (-115)
-30.5 (-105)
O 45.5 (-105)
U 45.5 (-115)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 63.5 (-105)
U 63.5 (-115)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-625
+455
-14.5 (-105)
+14.5 (-115)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-142
+120
-2.5 (-115)
+2.5 (-105)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1400
-3200
+25.5 (-110)
-25.5 (-110)
O 55.5 (-102)
U 55.5 (-118)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+180
-218
+5.5 (-110)
-5.5 (-110)
O 46.5 (-112)
U 46.5 (-108)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-345
+275
-9.5 (-108)
+9.5 (-112)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+230
-285
+7.5 (-115)
-7.5 (-105)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+410
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-112)
U 49.5 (-108)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Eastern Michigan Eagles vs. Buffalo Bulls on October 04, 2025 at UB Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN