Clemson vs North Carolina Prediction — AI Finds CAN'T MISS CFB Lines & Props (Oct 04)
Updated: 2025-09-27T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Clemson Tigers head to Chapel Hill on October 4, 2025 to face the North Carolina Tar Heels in a heavyweight ACC showdown that could reverberate through the conference standings. With Clemson looking to rebound from a rough start and UNC navigating the early days under new leadership, this matchup carries both urgency and intrigue for both programs.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Oct 04, 2025
Start Time: 12:00 PM EST
Venue: Kenan Stadium
Tar Heels Record: (2-2)
Tigers Record: (1-3)
OPENING ODDS
CLEM Moneyline: -599
UNC Moneyline: +435
CLEM Spread: -13.5
UNC Spread: +13.5
Over/Under: 45.5
CLEM
Betting Trends
- Clemson is currently 1–3 against the spread in 2025, a sign that while they may win some games outright, they haven’t consistently covered expectations on the road.
UNC
Betting Trends
- North Carolina’s ATS record is also mixed, as they’ve shown a tendency to fluctuate with line movements and performance swings early in the season.
MATCHUP TRENDS
- Oddsmakers have circled this game as one of the more volatile lines of the week, with Clemson as a road favorite—a status that invites scrutiny—while UNC’s unpredictable trajectory and home crowd potential could compress the spread or lead to late movement toward the Heels. The fact that Clemson’s early-season performance has been uneven deepens the betting intrigue, as bettors may debate whether the Tigers can deliver under pressure in hostile territory.
CLEM vs. UNC
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: B. Wesco over 57.5 Receiving Yards.
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Clemson vs North Carolina Prediction & Odds:
Free CFB Betting Insights for 10/4/25
Offensively, UNC has been inconsistent, alternating between explosive outings and stagnant performances, and their ability to find balance against Clemson’s defense will determine whether they can stay in this game, while defensively they have been opportunistic at times but vulnerable against stronger offensive lines and quick-strike passing attacks. The matchup in the trenches will likely decide much of the outcome, as Clemson’s offensive line will be tested by UNC’s front seven, which will try to disrupt timing and create turnovers, while Clemson’s defensive front must reassert dominance by plugging rushing lanes and forcing North Carolina’s quarterback into hurried decisions. Special teams could provide the hidden edge, as both programs have shown lapses in coverage units and inconsistency in the kicking game, and in a matchup with slim margins those plays could swing momentum dramatically. From a betting perspective, Clemson’s struggles against the spread raise concerns about their ability to deliver as a road favorite, while UNC’s volatility makes them dangerous as a home underdog capable of covering if the Tigers fail to put them away early. Ultimately, this matchup feels like a referendum game for both programs: Clemson needs to reestablish itself as a contender by winning convincingly in a tough road environment, while North Carolina, under new direction, has the chance to galvanize belief with a statement victory at home, and the team that avoids mistakes, wins on third down, and executes in the red zone will likely leave Chapel Hill with a crucial win in hand.
Another kickoff time announced:
— Clemson Football (@ClemsonFB) September 29, 2025
🏈: Clemson at Boston College
📆: Saturday, Oct. 11
📍: Chestnut Hill, Mass.
⏰: 7:30 p.m. ET
📺: ACCN pic.twitter.com/1mo7Rvovh5
Clemson Tigers CFB Preview
The Clemson Tigers travel to Chapel Hill on October 4, 2025 in a position they have not been accustomed to in recent years, carrying a disappointing 1–3 record and desperate to show they can still be considered a factor in the ACC race, and this matchup against North Carolina presents both an opportunity and a significant challenge. Offensively, Clemson has lacked the crisp execution that defined their peak seasons, averaging under 20 points per game and struggling to sustain drives due to turnovers, inefficiency in the red zone, and a lack of explosive plays when defenses tighten, but there are glimpses of potential in their nearly 1,000 yards of passing production that show what they could become if they limit mistakes. Their quarterback has the tools to stretch the field but has been plagued by inconsistency, so the Tigers will need to lean on their offensive line to provide clean pockets and on their running backs to balance the attack with more than the modest four yards per carry they’ve averaged so far, because without balance their offense has been predictable and easier to defend. The receivers remain talented enough to break games open, but timing and confidence have been lacking, and Clemson must establish rhythm early on the road to quiet the crowd and avoid letting UNC build confidence. Defensively, the Tigers have given up nearly 23 points per game and struggled in critical moments, with lapses in coverage and missed tackles costing them against both Georgia Tech and Syracuse, and they must return to form in the trenches by stuffing the run, creating negative plays, and forcing North Carolina’s quarterback into hurried decisions.
Clemson’s secondary will also be under pressure, as UNC has shown the ability to move the ball in spurts when allowed space, and the Tigers cannot afford to surrender cheap big plays that swing momentum. Special teams execution is another concern, as road games in hostile environments often turn on hidden yardage, so field position battles, punt coverage, and consistent kicking will be emphasized heavily by the coaching staff. From a betting perspective, Clemson is just 1–3 against the spread this season, a sign that even when favored they have underdelivered relative to expectations, and that trend adds pressure for them to not only win but do so convincingly enough to quiet concerns about whether they can handle their role as road favorites. Their path to victory will require a disciplined, balanced offensive effort, defensive sharpness in containing North Carolina’s playmakers, and the poise to avoid self-inflicted wounds like penalties and turnovers that have haunted them in the first month of the season. Ultimately, for Clemson this game is about proving they can respond to adversity, reestablish physicality on both sides of the ball, and take control of a matchup that on paper they should win, because anything less risks giving new life to North Carolina and raising deeper questions about whether the Tigers are capable of meeting their lofty standards in 2025.

Credit: USA TODAY/IMAGN
North Carolina Tar Heels CFB Preview
The North Carolina Tar Heels enter their October 4, 2025 showdown with Clemson at Kenan Stadium with a sense of anticipation and intrigue, as the program navigates its first season under Bill Belichick and faces the chance to earn a statement win in front of its home fans against an opponent with national pedigree but recent struggles, and this game offers UNC both the challenge of facing a desperate Tigers team and the opportunity to show that they can rise under pressure. Offensively, the Tar Heels have been inconsistent in the early season, scoring just 14 points in a lopsided loss to TCU but exploding for 41 in a rout of Richmond, reflecting both their potential and their volatility, and against Clemson they must find the balance necessary to sustain drives against a defense that, despite its flaws, is still loaded with talent. Establishing the run will be a priority, as it can set up play-action opportunities and prevent the Tigers from simply keying in on the passing game, but the quarterback must be decisive and avoid turnovers that have too often swung games against better competition. North Carolina’s offensive line will be tested by Clemson’s front seven, and their ability to protect in passing situations will be critical to allowing receivers to stretch the field and generate explosive plays.
Defensively, the Tar Heels will need to be opportunistic and aggressive, as Clemson has struggled to score and has been turnover-prone, and creating short fields through takeaways will give UNC’s offense a much-needed boost. The secondary must remain disciplined, as Clemson still has athletic receivers capable of changing the game with one big play, but forcing the Tigers into long, grinding drives increases the likelihood of mistakes. Special teams could also tilt the outcome, as UNC has shown flashes of strength in this phase and will look to capitalize on any lapses from Clemson in coverage or the kicking game. The home crowd at Kenan Stadium will be a factor, especially if the Tar Heels can generate early momentum, and Belichick’s presence adds an extra layer of intrigue as fans expect discipline, situational sharpness, and defensive creativity to be hallmarks of this team. From a betting perspective, UNC’s results have been inconsistent but they represent a live underdog, as Clemson’s 1–3 ATS record shows they have not met expectations even when favored, and if the Heels can keep this close into the second half, the pressure will swing squarely onto the Tigers. For North Carolina to pull off the upset, they must play clean football, avoid giving Clemson easy points, and take advantage of their opportunities in the red zone, because field goals will not be enough against a team that still carries talent and experience despite its slow start. Ultimately, the Tar Heels’ best chance lies in combining home-field energy with disciplined execution, forcing Clemson to prove it can handle adversity, and if they do that, UNC could leave this game not just with a cover but potentially one of the most impactful wins of their season.
And @OmarionHampton is GONE!
— Carolina Football (@UNCFootball) September 28, 2025
pic.twitter.com/MAXplK8XQk
Clemson vs. North Carolina Prop Picks (AI)
Clemson vs. North Carolina Prediction (AI)

Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every facet between the Tigers and Tar Heels and using recursive machine learning and cutting-edge AI to analyze the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most keyed in on the trending weight human bettors regularly put on player performance factors between a Tigers team going up against a possibly healthy Tar Heels team. We’ve found the true game analytics appear to reflect a strong lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Clemson vs North Carolina picks, computer picks Tigers vs Tar Heels, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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CFB | 10/21 | KENSAW@FIU | UNLOCK THIS PICK | 3 |
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CFB | 10/21 | WKY@LATECH | UNLOCK THIS PICK | 2 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Tigers Betting Trends
Clemson is currently 1–3 against the spread in 2025, a sign that while they may win some games outright, they haven’t consistently covered expectations on the road.
Tar Heels Betting Trends
North Carolina’s ATS record is also mixed, as they’ve shown a tendency to fluctuate with line movements and performance swings early in the season.
Tigers vs. Tar Heels Matchup Trends
Oddsmakers have circled this game as one of the more volatile lines of the week, with Clemson as a road favorite—a status that invites scrutiny—while UNC’s unpredictable trajectory and home crowd potential could compress the spread or lead to late movement toward the Heels. The fact that Clemson’s early-season performance has been uneven deepens the betting intrigue, as bettors may debate whether the Tigers can deliver under pressure in hostile territory.
Clemson vs. North Carolina Game Info
What time does Clemson vs North Carolina start on October 04, 2025?
Clemson vs North Carolina starts on October 04, 2025 at 12:00 PM EST.
Where is Clemson vs North Carolina being played?
Venue: Kenan Stadium.
What are the opening odds for Clemson vs North Carolina?
Spread: North Carolina +13.5
Moneyline: Clemson -599, North Carolina +435
Over/Under: 45.5
What are the records for Clemson vs North Carolina?
Clemson: (1-3) | North Carolina: (2-2)
What is the AI best bet for Clemson vs North Carolina?
Remi's searched hard and found the best prop for this matchup: B. Wesco over 57.5 Receiving Yards.. Prices move—always shop for the best number.
What are Clemson vs North Carolina trending bets?
Oddsmakers have circled this game as one of the more volatile lines of the week, with Clemson as a road favorite—a status that invites scrutiny—while UNC’s unpredictable trajectory and home crowd potential could compress the spread or lead to late movement toward the Heels. The fact that Clemson’s early-season performance has been uneven deepens the betting intrigue, as bettors may debate whether the Tigers can deliver under pressure in hostile territory.
What are Clemson trending bets?
CLEM trend: Clemson is currently 1–3 against the spread in 2025, a sign that while they may win some games outright, they haven’t consistently covered expectations on the road.
What are North Carolina trending bets?
UNC trend: North Carolina’s ATS record is also mixed, as they’ve shown a tendency to fluctuate with line movements and performance swings early in the season.
Where can I find AI Picks for Clemson vs North Carolina?
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
Clemson vs. North Carolina Odds
Remi is pouring through loads of data on each player. In fact, anytime the Clemson vs North Carolina trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude can often follow normal, predictable betting trends.
Clemson vs North Carolina Opening Odds
CLEM Moneyline:
-599 UNC Moneyline: +435
CLEM Spread: -13.5
UNC Spread: +13.5
Over/Under: 45.5
Clemson vs North Carolina Live Odds
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Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
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–
–
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-370
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-9.5 (-110)
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O 55.5 (-110)
U 55.5 (-110)
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Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
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–
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-108
-108
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-1.5 (-105)
+1.5 (-115)
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O 51.5 (-110)
U 51.5 (-110)
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Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
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–
–
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-225
+188
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-6.5 (-110)
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O 56.5 (-106)
U 56.5 (-114)
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Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
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–
–
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-4000
+1500
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-27.5 (-102)
+27.5 (-120)
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O 60.5 (-115)
U 60.5 (-105)
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Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
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–
–
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+160
-190
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+4.5 (-110)
-4.5 (-110)
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O 50.5 (-105)
U 50.5 (-115)
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Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
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–
–
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-1800
+980
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-21.5 (-105)
+21.5 (-115)
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O 50.5 (-110)
U 50.5 (-110)
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Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
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–
–
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-430
+330
|
-10.5 (-110)
+10.5 (-110)
|
O 51.5 (-110)
U 51.5 (-110)
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Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
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–
–
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-285
+230
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-7.5 (-105)
+7.5 (-115)
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O 48.5 (-110)
U 48.5 (-110)
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Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
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–
–
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-135
+115
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-2.5 (-110)
+2.5 (-110)
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O 58.5 (-110)
U 58.5 (-110)
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Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
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–
–
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-205
+168
|
-5.5 (-110)
+5.5 (-110)
|
O 63.5 (-106)
U 63.5 (-114)
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Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
|
–
–
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+1600
-4500
|
+25.5 (-110)
-25.5 (-110)
|
O 54.5 (-115)
U 54.5 (-105)
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Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
|
–
–
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+230
-285
|
+7.5 (-118)
-7.5 (-104)
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O 42.5 (-120)
U 42.5 (-102)
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Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
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–
–
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-450
+340
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-12.5 (-110)
+12.5 (-110)
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O 59.5 (-110)
U 59.5 (-110)
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Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
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–
–
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-170
+140
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-3.5 (-108)
+3.5 (-112)
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O 54.5 (-110)
U 54.5 (-110)
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Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
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–
–
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+610
-950
|
+17.5 (-115)
-17.5 (-105)
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O 53.5 (-110)
U 53.5 (-110)
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Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
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–
–
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-610
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-14.5 (-105)
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O 62.5 (-115)
U 62.5 (-105)
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Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
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–
–
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+172
-210
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+4.5 (-105)
-4.5 (-115)
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O 54.5 (-105)
U 54.5 (-115)
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Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
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–
–
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+122
-146
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+2.5 (+100)
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O 56.5 (-110)
U 56.5 (-110)
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Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
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–
–
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-110
-110
|
+1.5 (-115)
-1.5 (-105)
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O 57.5 (-105)
U 57.5 (-115)
|
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Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
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–
–
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+290
-375
|
+9.5 (-102)
-9.5 (-120)
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O 47.5 (-110)
U 47.5 (-110)
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Oct 25, 2025 3:00PM EDT
UConn Huskies
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10/25/25 3PM
UCONN
RICE
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–
–
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-400
+310
|
-10.5 (-110)
+10.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
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Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
|
–
–
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+122
-146
|
+2.5 (-102)
-2.5 (-120)
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O 61.5 (-110)
U 61.5 (-110)
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Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
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–
–
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+275
-350
|
+8.5 (-110)
-8.5 (-110)
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O 38.5 (-115)
U 38.5 (-105)
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Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
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–
–
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-520
+385
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-11.5 (-118)
+11.5 (-104)
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O 47.5 (-105)
U 47.5 (-115)
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Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
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–
–
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+122
-146
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+2.5 (+100)
-2.5 (-122)
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O 48.5 (-115)
U 48.5 (-105)
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Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
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–
–
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-225
+188
|
-5.5 (-120)
+5.5 (-102)
|
O 54.5 (-110)
U 54.5 (-110)
|
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Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
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–
–
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+176
-215
|
+5.5 (-110)
-5.5 (-110)
|
O 41.5 (-105)
U 41.5 (-115)
|
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Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
|
–
–
|
+104
-125
|
+1.5 (-105)
-1.5 (-115)
|
O 46.5 (-114)
U 46.5 (-106)
|
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Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
|
–
–
|
+480
-670
|
+15.5 (-110)
-15.5 (-110)
|
O 62.5 (-115)
U 62.5 (-105)
|
|
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
|
–
–
|
+146
-176
|
+4.5 (-115)
-4.5 (-105)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
|
–
–
|
-720
|
-15.5 (-115)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
|
–
–
|
-146
+122
|
-2.5 (-122)
+2.5 (+100)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
|
–
–
|
+115
-138
|
+2.5 (-106)
-2.5 (-114)
|
O 52.5 (-110)
U 52.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
|
–
–
|
+195
-240
|
+6.5 (-110)
-6.5 (-110)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
|
–
–
|
+106
|
+2.5 (-115)
|
O 41.5 (-110)
U 41.5 (-110)
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|
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
|
–
–
|
+310
|
+11.5 (-115)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
|
–
–
|
+2800
-10000
|
+37.5 (-108)
-37.5 (-112)
|
O 56.5 (-105)
U 56.5 (-115)
|
|
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
|
–
–
|
+152
-184
|
+4.5 (-115)
-4.5 (-105)
|
O 67.5 (-105)
U 67.5 (-115)
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Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
|
–
–
|
-285
+230
|
-7.5 (-102)
+7.5 (-120)
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O 44.5 (-120)
U 44.5 (-102)
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|
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
|
–
–
|
-670
+470
|
-15.5 (-112)
+15.5 (-108)
|
O 55.5 (-106)
U 55.5 (-114)
|
|
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
|
–
–
|
|
+33.5 (-106)
-33.5 (-114)
|
O 44.5 (-108)
U 44.5 (-112)
|
|
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
|
–
–
|
+270
-345
|
+9.5 (-110)
-9.5 (-110)
|
O 47.5 (-112)
U 47.5 (-108)
|
|
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
|
–
–
|
+4000
-30000
|
+30.5 (-115)
-30.5 (-105)
|
O 45.5 (-104)
U 45.5 (-118)
|
|
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
|
–
–
|
+106
-128
|
+1.5 (-105)
-1.5 (-115)
|
O 63.5 (-105)
U 63.5 (-115)
|
|
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
|
–
–
|
-630
+450
|
-14.5 (-105)
+14.5 (-115)
|
O 48.5 (-105)
U 48.5 (-115)
|
|
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
|
–
–
|
-144
+120
|
-2.5 (-120)
+2.5 (-102)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
|
–
–
|
+1600
-4500
|
+25.5 (-110)
-25.5 (-110)
|
O 55.5 (-104)
U 55.5 (-118)
|
|
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
|
–
–
|
+184
-225
|
+5.5 (-104)
-5.5 (-118)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
|
–
–
|
-345
+270
|
-9.5 (-110)
+9.5 (-110)
|
O 53.5 (-118)
U 53.5 (-104)
|
|
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
|
–
–
|
+220
-275
|
+7.5 (-120)
-7.5 (-102)
|
O 46.5 (-115)
U 46.5 (-105)
|
|
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
|
–
–
|
+375
-500
|
+13.5 (-110)
-13.5 (-110)
|
O 49.5 (-115)
U 49.5 (-105)
|
|
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
|
–
–
|
-275
+220
|
-7.5 (-104)
+7.5 (-118)
|
O 60.5 (-112)
U 60.5 (-108)
|
|
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
|
–
–
|
-200
+164
|
-5.5 (-110)
+5.5 (-110)
|
O 52.5 (-112)
U 52.5 (-108)
|
|
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
|
–
–
|
+660
-1050
|
+17.5 (-115)
-17.5 (-105)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
|
–
–
|
-430
+330
|
-10.5 (-110)
+10.5 (-110)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
|
–
–
|
-105
-114
|
+1.5 (-114)
-1.5 (-106)
|
O 53.5 (-112)
U 53.5 (-108)
|
|
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
|
–
–
|
+150
-182
|
+3.5 (-106)
-3.5 (-114)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
|
–
–
|
-300
+240
|
-7.5 (-110)
+7.5 (-110)
|
O 50.5 (-112)
U 50.5 (-108)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Clemson Tigers vs. North Carolina Tar Heels on October 04, 2025 at Kenan Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
FSU@STNFRD | STNFRD +18 | 56.6% | 6 | WIN |
WASHST@UVA | WASHST +17.5 | 58.8% | 8 | WIN |
NEVADA@NMEX | NEVADA +13.5 | 57.8% | 7 | WIN |
TEXAS@UK | ARCH MANNING UNDER 1.5 PASS TD | 56.1% | 6 | WIN |
ARMY@TULANE | ARMY +10 | 55.3% | 5 | WIN |
SJST@UTAHST | SJST +4 | 54.4% | 4 | LOSS |
LVILLE@MIAMI | LVILLE +12.5 | 56.5% | 6 | WIN |
LVILLE@MIAMI | CJ DANIELS UNDER 4.5 RECEPTIONS | 54.4 | 4 | LOSS |
DEL@JAXST | DEL -2.5 | 57.6% | 6 | LOSS |
UTEP@SAMST | UTEP -2.5 | 53.9% | 3 | WIN |
FIU@WKY | FIU +10.5 | 54.6% | 4 | WIN |
ARKST@SALA | ARKST +7.5 | 54.5% | 4 | WIN |
ARKST@SALA | JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP | 53.3% | 3 | WIN |
SJST@WYO | SJST -120 | 59.8% | 7 | LOSS |
UMASS@KENTST | KENTST -135 | 60.2% | 6 | WIN |
NOILL@EMICH | EMICH +2.5 | 53.9% | 3 | WIN |
BYU@ARIZ | ARIZ +2.5 | 54.2% | 3 | LOSS |
OKLA@TEXAS | OKLA +2.5 | 54.7% | 4 | LOSS |
NMEX@BOISE | NMEX +16.5 | 56.4% | 6 | WIN |
WAKE@OREGST | WAKE -2.5 | 56.7% | 6 | WIN |
ULMON@COASTAL | ULMON -2.5 | 56.8% | 6 | LOSS |
IOWA@WISC | WISC +4 | 54.8% | 4 | LOSS |
TOLEDO@BGREEN | TOLEDO -10 | 56.3% | 6 | LOSS |
SFLA@NOTEX | SFLA +2.5 | 54.3% | 4 | WIN |
FRESNO@COLOST | RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 | 54.4% | 4 | LOSS |
JAXST@SAMST | SAMST +7.5 | 55.3% | 5 | WIN |
USM@GAS | GAS +3.5 | 57.4% | 7 | WIN |
LIB@UTEP | UTEP +2 | 54.5% | 4 | LOSS |
SALA@TROY | SALA -118 | 55.2% | 4 | LOSS |
TULSA@MEMP | MEMP -20.5 | 53.8% | 3 | WIN |
JMAD@GAST | GAST +20.5 | 54.6% | 4 | WIN |
WAKE@VATECH | VATECH -5.5 | 56.6% | 6 | LOSS |
UNLV@WYO | WYO +4.5 | 55.5% | 5 | LOSS |
PSU@UCLA | PSU -24.5 | 56.3% | 6 | LOSS |
TXSTSM@ARKST | TXSTSM -13 | 56.7% | 6 | LOSS |
UVA@LVILLE | ISAAC BROWN OVER 70.5 RUSH YDS | 56.6% | 6 | LOSS |
WVU@BYU | WVU +20.5 | 54.7% | 4 | WIN |
SAMST@NMEXST | SAMST -1.5 | 54.1% | 3 | LOSS |
EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
UK@SC | SC -5.5 | 54.8% | 4 | WIN |
WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |