UConn vs Buffalo Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 27)
Updated: 2025-09-20T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The UConn Huskies will head to Buffalo to face the Bulls on September 27, 2025, in a nonconference matchup that will test the resilience and progress of two programs fighting to carve out more consistency. Both teams lean heavily on physical ground games and opportunistic defenses, setting the stage for a hard-fought contest that could swing on turnovers and execution in the trenches.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 27, 2025
Start Time: 3:30 PM EST
Venue: UB Stadium
Bulls Record: (2-2)
Huskies Record: (2-2)
OPENING ODDS
UCONN Moneyline: -178
BUFF Moneyline: +147
UCONN Spread: -4
BUFF Spread: +4
Over/Under: 49.5
UCONN
Betting Trends
- UConn has struggled to cover spreads consistently on the road, especially when their offense has fallen behind early and been forced away from their run-heavy identity.
BUFF
Betting Trends
- Buffalo has fared better ATS at home, often capitalizing on their strong rushing attack and crowd energy to control tempo and cover in closely lined games.
MATCHUP TRENDS
- Historically, meetings between UConn and Buffalo have trended toward the under, with defensive battles and limited explosive plays keeping games close and often within one possession late.
UCONN vs. BUFF
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup, but hasn't found a good Prop Bet yet for this game.
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UConn vs Buffalo Prediction & Odds:
Free CFB Betting Insights for 9/27/25
Defensively, UConn will lean on its linebackers and front seven to set the tone, as Buffalo’s rushing attack is the centerpiece of their offense, and the Huskies must stay disciplined in their run fits while also remaining alert to play-action shots designed to exploit over-aggressive defenders. Buffalo, meanwhile, will look to dictate tempo with its power run game, built around a physical offensive line and backs who can wear down defenses, and their quarterback’s ability to complement that with timely throws will be crucial to keeping UConn off balance. The Bulls’ defense has been opportunistic, thriving when they can pin opponents in long-yardage situations, and at home they will be eager to pressure UConn’s offense into mistakes. Special teams may also prove decisive, as both teams have had narrow margins for error in recent seasons, and a missed field goal or blown coverage could tilt momentum sharply in one direction. Beyond the Xs and Os, the intangibles are critical: UConn must overcome the challenges of playing on the road, where they have historically struggled, while Buffalo will look to feed off the energy of its home crowd to create an environment that amplifies small mistakes into big swings. Both coaching staffs will stress the importance of discipline and execution, as this matchup is unlikely to feature wide-open offensive fireworks but rather a methodical, grind-it-out pace where turnovers, penalties, and red-zone efficiency will define the outcome. Ultimately, this contest shapes up as a battle of wills between two programs still seeking consistency, and whichever team executes its identity more effectively—whether that means UConn finding just enough passing balance to complement its run game or Buffalo leaning on its home-field advantage and rushing attack to wear down the Huskies—will likely walk away with a win in what promises to be a tightly contested, old-school style of football game.
Week 5️⃣ Buffalo Bound!#HuskiesOverEveryone pic.twitter.com/48X3yYLzV5
— UConn Football (@UConnFootball) September 22, 2025
UConn Huskies CFB Preview
The UConn Huskies head to Buffalo on September 27, 2025, knowing that to come away with a road win they will need to show resilience, discipline, and a willingness to lean on their defensive identity while hoping their offense can generate enough balance to keep the Bulls from controlling tempo. UConn’s offense has long been predicated on establishing the run, using a steady rotation of backs to wear down opposing defenses, and their offensive line will be tasked with handling Buffalo’s stout defensive front that thrives on disrupting rushing lanes and forcing offenses into predictable passing situations. The Huskies’ quarterback, while not often asked to carry the offense, must be efficient in completing high-percentage throws and extending drives on third down, because if UConn falls behind early and is forced to abandon the run, they will be at a severe disadvantage against an opportunistic Bulls defense. The wide receiver group will need to step up and create separation, as big plays through the air have been rare for the Huskies, but hitting one or two explosive passes could be the difference in loosening up Buffalo’s defense and creating more room for the ground game to operate.
Defensively, UConn’s front seven will be under immense pressure to remain disciplined against Buffalo’s power rushing attack, and their linebackers in particular will be critical in filling gaps and limiting yards after contact, as the Bulls thrive on wearing down opponents over four quarters. The Huskies’ secondary must also stay sharp, as while Buffalo does not throw often, their play-action passing game can produce momentum-shifting completions if defenders bite too hard on the run. Special teams execution will be vital for UConn, as flipping field position, making key kicks, and avoiding coverage breakdowns could give them the margin they need in what is likely to be a low-scoring, possession-driven contest. Beyond the Xs and Os, UConn’s greatest hurdle may be mental, as their track record on the road has been inconsistent, and handling the hostile environment at UB Stadium will require composure and leadership from veterans who can keep the team focused through adversity. The coaching staff will stress the importance of mistake-free football, because penalties, turnovers, and missed assignments are magnified in games where possessions are limited and scoring opportunities are scarce. For the Huskies, the path to victory is clear but difficult: they must control the clock with sustained drives, win the turnover battle, and keep Buffalo from dictating pace with its running game, all while finding just enough offensive balance to capitalize on scoring chances when they arise. If UConn can execute that blueprint, they have the potential to grind out a road win that would be both a morale boost and a statement about their progress as a program, but if they falter early or allow Buffalo’s physicality to dictate terms, it could become yet another frustrating road trip that highlights the gap between where they are and where they want to be.

Credit: USA TODAY/IMAGN
Buffalo Bulls CFB Preview
The Buffalo Bulls will host the UConn Huskies on September 27, 2025, at UB Stadium with the confidence of a team that understands how to maximize its strengths at home, and they will look to impose their physical identity from the opening kickoff by leaning on a ground game that has long been the heartbeat of their program. Offensively, Buffalo thrives when their offensive line is able to take control of the trenches, opening holes for a backfield that features both bruising power runners and shifty change-of-pace options who can turn short gains into chain-moving plays, and that commitment to the run has allowed their quarterbacks to operate efficiently in play-action situations. The Bulls’ passing game is not built to air it out with frequency, but when used sparingly it is highly effective, as their receivers are capable of stretching defenses just enough to prevent opponents from selling out against the run, and the ability to hit one or two explosive plays through the air could be the difference against a UConn defense that will be keying on their ground attack. Defensively, Buffalo has built a reputation for toughness and opportunism, with a front seven that excels at plugging rushing lanes and creating pressure, and they will likely aim to force UConn’s offense into third-and-long situations that expose the Huskies’ limitations in the passing game.
The Bulls’ linebackers are quick to diagnose plays and are strong tacklers, while their secondary, though not loaded with elite playmakers, is disciplined enough to keep opponents in front of them and minimize big plays. Playing at home gives Buffalo additional advantages, as UB Stadium’s energy and the routine of playing on familiar turf have historically helped them perform better against the spread and sustain momentum through four quarters. Special teams could also prove decisive, with Buffalo’s kicking game and return units poised to tilt field position in what is expected to be a low-possession, defensive-minded battle, and capitalizing on these hidden yards could be a key factor in pulling away late. The coaching staff will emphasize composure and execution, knowing that a matchup against UConn is unlikely to be flashy and instead will be won in the margins, through physicality, discipline, and mistake-free football. For Buffalo, the formula for success is straightforward: establish the run early to control the clock, force UConn into uncomfortable passing situations, and seize momentum with timely defensive stops and special teams execution, all while letting their home-field advantage magnify their edge. If they can follow that blueprint, the Bulls not only stand an excellent chance of beating UConn but also of reaffirming their identity as a team that is difficult to outmuscle, particularly in Buffalo, where their brand of football finds its most natural rhythm.
𝐀𝐥𝐥 𝐛𝐥𝐮𝐞 𝐞𝐯𝐞𝐫𝐲𝐭𝐡𝐢𝐧𝐠 𝐟𝐨𝐫 𝐒𝐚𝐭𝐮𝐫𝐝𝐚𝐲’𝐬 𝐇𝐞𝐫𝐨𝐞𝐬 𝐆𝐚𝐦𝐞 🇺🇸
— UB Football (@UBFootball) September 24, 2025
🔵🔵🔵#UBhornsUP🤘l #BullMarket📈 pic.twitter.com/UBB4Yn1BOu
UConn vs. Buffalo Prop Picks (AI)
UConn vs. Buffalo Prediction (AI)

Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every simulation between the Huskies and Bulls and using recursive machine learning and impressive AI to examine the data to a single cover probability.
Remi has been most watching on the unproportionally assigned factor knucklehead sportsbettors regularly put on UConn’s strength factors between a Huskies team going up against a possibly healthy Bulls team. We’ve found the true game analytics might reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI UConn vs Buffalo picks, computer picks Huskies vs Bulls, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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CFB | 10/21 | KENSAW@FIU | UNLOCK THIS PICK | 3 |
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CFB | 10/21 | WKY@LATECH | UNLOCK THIS PICK | 2 |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Huskies Betting Trends
UConn has struggled to cover spreads consistently on the road, especially when their offense has fallen behind early and been forced away from their run-heavy identity.
Bulls Betting Trends
Buffalo has fared better ATS at home, often capitalizing on their strong rushing attack and crowd energy to control tempo and cover in closely lined games.
Huskies vs. Bulls Matchup Trends
Historically, meetings between UConn and Buffalo have trended toward the under, with defensive battles and limited explosive plays keeping games close and often within one possession late.
UConn vs. Buffalo Game Info
What time does UConn vs Buffalo start on September 27, 2025?
UConn vs Buffalo starts on September 27, 2025 at 3:30 PM EST.
Where is UConn vs Buffalo being played?
Venue: UB Stadium.
What are the opening odds for UConn vs Buffalo?
Spread: Buffalo +4
Moneyline: UConn -178, Buffalo +147
Over/Under: 49.5
What are the records for UConn vs Buffalo?
UConn: (2-2) | Buffalo: (2-2)
What is the AI best bet for UConn vs Buffalo?
Remi's searched hard and found the best prop for this matchup, but hasn't found a good Prop Bet yet for this game.. Prices move—always shop for the best number.
What are UConn vs Buffalo trending bets?
Historically, meetings between UConn and Buffalo have trended toward the under, with defensive battles and limited explosive plays keeping games close and often within one possession late.
What are UConn trending bets?
UCONN trend: UConn has struggled to cover spreads consistently on the road, especially when their offense has fallen behind early and been forced away from their run-heavy identity.
What are Buffalo trending bets?
BUFF trend: Buffalo has fared better ATS at home, often capitalizing on their strong rushing attack and crowd energy to control tempo and cover in closely lined games.
Where can I find AI Picks for UConn vs Buffalo?
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
UConn vs. Buffalo Odds
Remi is pouring through loads of stats on each line. In fact, anytime the UConn vs Buffalo trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable patterns.
UConn vs Buffalo Opening Odds
UCONN Moneyline:
-178 BUFF Moneyline: +147
UCONN Spread: -4
BUFF Spread: +4
Over/Under: 49.5
UConn vs Buffalo Live Odds
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MTSU Blue Raiders
Delaware Blue Hens
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MTSU
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–
–
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-370
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-9.5 (-110)
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O 55.5 (-110)
U 55.5 (-110)
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Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
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–
–
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-108
-108
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-1.5 (-105)
+1.5 (-115)
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O 51.5 (-110)
U 51.5 (-110)
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Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
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–
–
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-225
+188
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-6.5 (-110)
+6.5 (-110)
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O 56.5 (-106)
U 56.5 (-114)
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Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
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–
–
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-4000
+1500
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-27.5 (-102)
+27.5 (-120)
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O 60.5 (-115)
U 60.5 (-105)
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Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
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–
–
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+160
-190
|
+4.5 (-110)
-4.5 (-110)
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O 50.5 (-105)
U 50.5 (-115)
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Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
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–
–
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-1800
+980
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-21.5 (-105)
+21.5 (-115)
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O 50.5 (-110)
U 50.5 (-110)
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Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
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–
–
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-430
+330
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-10.5 (-110)
+10.5 (-110)
|
O 51.5 (-110)
U 51.5 (-110)
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Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
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–
–
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-285
+230
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-7.5 (-105)
+7.5 (-115)
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O 48.5 (-110)
U 48.5 (-110)
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Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
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–
–
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-135
+115
|
-2.5 (-110)
+2.5 (-110)
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O 58.5 (-110)
U 58.5 (-110)
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Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
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–
–
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-205
+168
|
-5.5 (-110)
+5.5 (-110)
|
O 63.5 (-106)
U 63.5 (-114)
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Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
|
–
–
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+1600
-4500
|
+25.5 (-110)
-25.5 (-110)
|
O 54.5 (-115)
U 54.5 (-105)
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Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
|
–
–
|
+230
-285
|
+7.5 (-118)
-7.5 (-104)
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O 42.5 (-120)
U 42.5 (-102)
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Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
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–
–
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-450
+340
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-12.5 (-110)
+12.5 (-110)
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O 59.5 (-110)
U 59.5 (-110)
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Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
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–
–
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-170
+140
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-3.5 (-108)
+3.5 (-112)
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O 54.5 (-110)
U 54.5 (-110)
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Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
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–
–
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+610
-950
|
+17.5 (-115)
-17.5 (-105)
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O 53.5 (-110)
U 53.5 (-110)
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Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
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–
–
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-610
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-14.5 (-105)
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O 62.5 (-115)
U 62.5 (-105)
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Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
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–
–
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+172
-210
|
+4.5 (-105)
-4.5 (-115)
|
O 54.5 (-105)
U 54.5 (-115)
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Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
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–
–
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+122
-146
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+2.5 (+100)
-2.5 (-122)
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O 56.5 (-110)
U 56.5 (-110)
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Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
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–
–
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-110
-110
|
+1.5 (-115)
-1.5 (-105)
|
O 57.5 (-105)
U 57.5 (-115)
|
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Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
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–
–
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+290
-375
|
+9.5 (-102)
-9.5 (-120)
|
O 47.5 (-110)
U 47.5 (-110)
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Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
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–
–
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-400
+310
|
-10.5 (-110)
+10.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
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Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
|
–
–
|
+122
-146
|
+2.5 (-102)
-2.5 (-120)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
|
–
–
|
+275
-350
|
+8.5 (-110)
-8.5 (-110)
|
O 38.5 (-115)
U 38.5 (-105)
|
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Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
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–
–
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-520
+385
|
-11.5 (-118)
+11.5 (-104)
|
O 47.5 (-105)
U 47.5 (-115)
|
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Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
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–
–
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+122
-146
|
+2.5 (+100)
-2.5 (-122)
|
O 48.5 (-115)
U 48.5 (-105)
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Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
|
–
–
|
-225
+188
|
-5.5 (-120)
+5.5 (-102)
|
O 54.5 (-110)
U 54.5 (-110)
|
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Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
|
–
–
|
+176
-215
|
+5.5 (-110)
-5.5 (-110)
|
O 41.5 (-105)
U 41.5 (-115)
|
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Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
|
–
–
|
+104
-125
|
+1.5 (-105)
-1.5 (-115)
|
O 46.5 (-114)
U 46.5 (-106)
|
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Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
|
–
–
|
+480
-670
|
+15.5 (-110)
-15.5 (-110)
|
O 62.5 (-115)
U 62.5 (-105)
|
|
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
|
–
–
|
+146
-176
|
+4.5 (-115)
-4.5 (-105)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
|
–
–
|
-720
|
-15.5 (-115)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
|
–
–
|
-146
+122
|
-2.5 (-122)
+2.5 (+100)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
|
–
–
|
+115
-138
|
+2.5 (-106)
-2.5 (-114)
|
O 52.5 (-110)
U 52.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
|
–
–
|
+195
-240
|
+6.5 (-110)
-6.5 (-110)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
|
–
–
|
+106
|
+2.5 (-115)
|
O 41.5 (-110)
U 41.5 (-110)
|
|
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
|
–
–
|
+310
|
+11.5 (-115)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
|
–
–
|
+2800
-10000
|
+37.5 (-108)
-37.5 (-112)
|
O 56.5 (-105)
U 56.5 (-115)
|
|
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
|
–
–
|
+152
-184
|
+4.5 (-115)
-4.5 (-105)
|
O 67.5 (-105)
U 67.5 (-115)
|
|
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
|
–
–
|
-285
+230
|
-7.5 (-102)
+7.5 (-120)
|
O 44.5 (-120)
U 44.5 (-102)
|
|
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
|
–
–
|
-670
+470
|
-15.5 (-112)
+15.5 (-108)
|
O 55.5 (-106)
U 55.5 (-114)
|
|
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
|
–
–
|
|
+33.5 (-106)
-33.5 (-114)
|
O 44.5 (-108)
U 44.5 (-112)
|
|
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
|
–
–
|
+270
-345
|
+9.5 (-110)
-9.5 (-110)
|
O 47.5 (-112)
U 47.5 (-108)
|
|
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
|
–
–
|
+4000
-30000
|
+30.5 (-115)
-30.5 (-105)
|
O 45.5 (-104)
U 45.5 (-118)
|
|
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
|
–
–
|
+106
-128
|
+1.5 (-105)
-1.5 (-115)
|
O 63.5 (-105)
U 63.5 (-115)
|
|
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
|
–
–
|
-630
+450
|
-14.5 (-105)
+14.5 (-115)
|
O 48.5 (-105)
U 48.5 (-115)
|
|
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
|
–
–
|
-144
+120
|
-2.5 (-120)
+2.5 (-102)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
|
–
–
|
+1600
-4500
|
+25.5 (-110)
-25.5 (-110)
|
O 55.5 (-104)
U 55.5 (-118)
|
|
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
|
–
–
|
+184
-225
|
+5.5 (-104)
-5.5 (-118)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
|
–
–
|
-345
+270
|
-9.5 (-110)
+9.5 (-110)
|
O 53.5 (-118)
U 53.5 (-104)
|
|
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
|
–
–
|
+220
-275
|
+7.5 (-120)
-7.5 (-102)
|
O 46.5 (-115)
U 46.5 (-105)
|
|
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
|
–
–
|
+375
-500
|
+13.5 (-110)
-13.5 (-110)
|
O 49.5 (-115)
U 49.5 (-105)
|
|
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
|
–
–
|
-275
+220
|
-7.5 (-104)
+7.5 (-118)
|
O 60.5 (-112)
U 60.5 (-108)
|
|
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
|
–
–
|
-200
+164
|
-5.5 (-110)
+5.5 (-110)
|
O 52.5 (-112)
U 52.5 (-108)
|
|
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
|
–
–
|
+660
-1050
|
+17.5 (-115)
-17.5 (-105)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
|
–
–
|
-430
+330
|
-10.5 (-110)
+10.5 (-110)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
|
–
–
|
-105
-114
|
+1.5 (-114)
-1.5 (-106)
|
O 53.5 (-112)
U 53.5 (-108)
|
|
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
|
–
–
|
+150
-182
|
+3.5 (-106)
-3.5 (-114)
|
O 45.5 (-110)
U 45.5 (-110)
|
|
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
|
–
–
|
-300
+240
|
-7.5 (-110)
+7.5 (-110)
|
O 50.5 (-112)
U 50.5 (-108)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers UConn Huskies vs. Buffalo Bulls on September 27, 2025 at UB Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
FSU@STNFRD | STNFRD +18 | 56.6% | 6 | WIN |
WASHST@UVA | WASHST +17.5 | 58.8% | 8 | WIN |
NEVADA@NMEX | NEVADA +13.5 | 57.8% | 7 | WIN |
TEXAS@UK | ARCH MANNING UNDER 1.5 PASS TD | 56.1% | 6 | WIN |
ARMY@TULANE | ARMY +10 | 55.3% | 5 | WIN |
SJST@UTAHST | SJST +4 | 54.4% | 4 | LOSS |
LVILLE@MIAMI | LVILLE +12.5 | 56.5% | 6 | WIN |
LVILLE@MIAMI | CJ DANIELS UNDER 4.5 RECEPTIONS | 54.4 | 4 | LOSS |
DEL@JAXST | DEL -2.5 | 57.6% | 6 | LOSS |
UTEP@SAMST | UTEP -2.5 | 53.9% | 3 | WIN |
FIU@WKY | FIU +10.5 | 54.6% | 4 | WIN |
ARKST@SALA | ARKST +7.5 | 54.5% | 4 | WIN |
ARKST@SALA | JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP | 53.3% | 3 | WIN |
SJST@WYO | SJST -120 | 59.8% | 7 | LOSS |
UMASS@KENTST | KENTST -135 | 60.2% | 6 | WIN |
NOILL@EMICH | EMICH +2.5 | 53.9% | 3 | WIN |
BYU@ARIZ | ARIZ +2.5 | 54.2% | 3 | LOSS |
OKLA@TEXAS | OKLA +2.5 | 54.7% | 4 | LOSS |
NMEX@BOISE | NMEX +16.5 | 56.4% | 6 | WIN |
WAKE@OREGST | WAKE -2.5 | 56.7% | 6 | WIN |
ULMON@COASTAL | ULMON -2.5 | 56.8% | 6 | LOSS |
IOWA@WISC | WISC +4 | 54.8% | 4 | LOSS |
TOLEDO@BGREEN | TOLEDO -10 | 56.3% | 6 | LOSS |
SFLA@NOTEX | SFLA +2.5 | 54.3% | 4 | WIN |
FRESNO@COLOST | RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 | 54.4% | 4 | LOSS |
JAXST@SAMST | SAMST +7.5 | 55.3% | 5 | WIN |
USM@GAS | GAS +3.5 | 57.4% | 7 | WIN |
LIB@UTEP | UTEP +2 | 54.5% | 4 | LOSS |
SALA@TROY | SALA -118 | 55.2% | 4 | LOSS |
TULSA@MEMP | MEMP -20.5 | 53.8% | 3 | WIN |
JMAD@GAST | GAST +20.5 | 54.6% | 4 | WIN |
WAKE@VATECH | VATECH -5.5 | 56.6% | 6 | LOSS |
UNLV@WYO | WYO +4.5 | 55.5% | 5 | LOSS |
PSU@UCLA | PSU -24.5 | 56.3% | 6 | LOSS |
TXSTSM@ARKST | TXSTSM -13 | 56.7% | 6 | LOSS |
UVA@LVILLE | ISAAC BROWN OVER 70.5 RUSH YDS | 56.6% | 6 | LOSS |
WVU@BYU | WVU +20.5 | 54.7% | 4 | WIN |
SAMST@NMEXST | SAMST -1.5 | 54.1% | 3 | LOSS |
EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
UK@SC | SC -5.5 | 54.8% | 4 | WIN |
WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |