Tigers vs. Rebels
Prediction, Odds & Props
Sep 27 | CFB AI Picks
Updated: 2025-09-20T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The SEC spotlight will shine brightly on September 27, 2025, as the LSU Tigers travel to Oxford to face the Ole Miss Rebels in a clash loaded with playoff implications and star power. Both programs bring explosive offenses and physical defenses, setting the stage for one of the weekend’s most anticipated showdowns.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 27, 2025
Start Time: 3:30 PM EST
Venue: Vaught-Hemingway Stadium at Hollingsworth Field
Rebels Record: (4-0)
Tigers Record: (4-0)
OPENING ODDS
LSU Moneyline: -105
OLEMISS Moneyline: -115
LSU Spread: +1.5
OLEMISS Spread: -1.5
Over/Under: 54.5
LSU
Betting Trends
- LSU has struggled recently against the spread on the road in SEC play, often finding themselves in closer-than-expected battles due to defensive lapses and inconsistent execution.
OLEMISS
Betting Trends
- Ole Miss has been strong against the spread at home, especially in high-profile conference games, covering in a majority of their recent contests thanks to a potent passing attack and timely defensive stops.
MATCHUP TRENDS
- Games between LSU and Ole Miss have historically leaned toward high-scoring affairs, with the over hitting frequently in recent years, and both teams are known for late-game drama that often swings the ATS outcome in the final minutes.
LSU vs. OLEMISS
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: Z. Thomas under 29.5 Receiving Yards.
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LSU vs Ole Miss Prediction & Odds:
Free CFB Betting Insights for 9/27/25
On the other side, Ole Miss enters the game with one of the most feared attacks in college football, built around an experienced quarterback who has been accurate, mobile, and comfortable directing tempo-driven schemes that keep defenses on their heels, and a receiving corps that combines speed and precision route running to create mismatches across the field. Their ground game has also been efficient, giving them the flexibility to control tempo when necessary, while their offensive line has provided enough protection to keep their quarterback upright and their system humming. Defensively, Ole Miss has made strides in recent years, becoming more opportunistic by generating turnovers and finding ways to make stops in the red zone, but consistency remains a concern, particularly against elite physical teams like LSU who can lean on their athletes and depth. Special teams could also play a decisive role, as both squads boast dependable kickers and dangerous return men who can flip momentum in a single play, making field position battles critical in a game expected to feature points in bunches. The coaching chess match between two aggressive staffs adds yet another layer, as both programs are unafraid to take risks, whether through fourth-down gambles, trick plays, or up-tempo sequences, and those decisions could very well decide the outcome in what projects as a shootout. Ultimately, this matchup appears destined to hinge on which defense can generate more stops and which offense can avoid costly turnovers in high-leverage moments, and with the margin for error razor-thin in a rivalry that has produced plenty of fireworks in the past, fans and analysts alike should be ready for a Saturday night thriller that could go a long way toward determining who stays alive in the race for SEC supremacy.
Saturday at 2:30 in Oxford
— LSU Football (@LSUfootball) September 24, 2025
Tigers vs. Rebels pic.twitter.com/kAL0NCmLiz
LSU Tigers CFB Preview
The LSU Tigers come into Oxford for their September 27, 2025 showdown with the Ole Miss Rebels knowing full well the stakes are enormous, not only for their SEC West positioning but also for their broader playoff aspirations, and they will be determined to deliver the kind of road performance that quiets the doubters and solidifies their reputation as one of the country’s true heavyweights. LSU’s offense will be the centerpiece of their hopes, led by a quarterback whose poise under pressure, ability to extend plays, and pinpoint accuracy have made him a consistent difference-maker throughout the season, and he will lean on a talented group of wide receivers who can overwhelm secondaries with speed, size, and versatility, stretching defenses both vertically and horizontally. The Tigers’ offensive line, while occasionally tested by aggressive fronts, has shown enough cohesion to provide a clean pocket and open running lanes, giving their backs the chance to churn out tough yards and keep defenses honest, which will be crucial against an Ole Miss unit that thrives when it can focus on stopping one dimension. The running game, while perhaps not the juggernaut of LSU’s glory days, has still proven effective in critical downs and red-zone situations, giving the Tigers a valuable tool for finishing drives, something that could be especially pivotal in a game where touchdowns, not field goals, will likely decide the winner.
Defensively, LSU’s trademark speed and athleticism remain their calling card, with a front that can generate pressure without heavy blitzing, linebackers capable of covering ground and neutralizing perimeter plays, and a secondary filled with NFL-level talent that has both the ball-hawking instincts to create turnovers and the size to match up with physical receivers, though their susceptibility to giving up the occasional deep shot remains a concern. The challenge will be limiting Ole Miss’s tempo and explosive playmaking, because once the Rebels find rhythm at home, it is nearly impossible to slow them down, and LSU knows discipline, gap control, and communication will have to be sharp to avoid falling behind early. Special teams could also become a swing factor, as the Tigers have traditionally leaned on strong kicking, coverage units, and return men to tilt field position in their favor, and in a hostile road environment, every yard matters. Psychologically, LSU embraces the underdog mentality that comes with playing on the road in a hostile SEC venue, and their coaching staff will lean on the program’s tradition of toughness, resilience, and “next man up” mentality to prepare their players for the intensity of this matchup. The Tigers’ formula for success will be to weather the early storm from Ole Miss, establish offensive rhythm through balance, and rely on their defense to generate a few key stops that can swing momentum in their favor. For LSU, a win in Oxford would not only reaffirm their place among the SEC’s elite but also serve as a critical stepping stone toward a playoff run, and they will approach this game with the urgency and focus of a team that knows its championship window is very much open.

Credit: USA TODAY/IMAGN
Ole Miss Rebels CFB Preview
The Ole Miss Rebels step onto their home field at Vaught-Hemingway Stadium on September 27, 2025, ready to defend their turf in what has become one of the SEC’s most compelling rivalries, and they understand that this game against LSU could go a long way in determining both their standing in the SEC West and their viability as a playoff contender, making it one of the most pivotal Saturdays of their season. Offensively, the Rebels have built a reputation for being one of the most electric units in college football, with a quarterback who is equally comfortable firing darts from the pocket or creating chaos with his legs, and he will be tasked with exploiting LSU’s tendency to give up the occasional deep play while keeping his offense operating at its signature fast tempo. Ole Miss’s receiving corps is loaded with versatile playmakers capable of stretching the field vertically and punishing secondaries with yards after the catch, and their offensive scheme thrives on quick reads and misdirection, often leaving defenders grasping at air. Complementing that is a ground game that, while not as headline-grabbing as their passing attack, is efficient and physical enough to keep defenses honest, with their offensive line showing steady improvement in both protection and run blocking, giving the Rebels the balance they need to sustain drives and finish in the red zone.
Defensively, Ole Miss has taken steps forward in recent seasons, showing a greater ability to generate turnovers, get stops on third down, and pressure quarterbacks with a defensive front that rotates effectively to stay fresh late in games, though questions remain about their ability to handle a team like LSU that can test them with both power and speed. The secondary has shown flashes of being opportunistic, but it will face one of its toughest tests of the season against LSU’s loaded receiver group, and their ability to keep plays in front of them while tackling consistently in the open field will be vital. Special teams for the Rebels have been reliable, with a dependable kicker and return units capable of sparking momentum swings, and in a matchup expected to be tight throughout, those hidden yards could prove decisive. Beyond the Xs and Os, Ole Miss will lean heavily on the energy of its home crowd, one of the rowdiest in the SEC, to create chaos for LSU’s communication and fuel their own confidence, as the Rebels have historically thrived when feeding off that atmosphere. The coaching staff’s aggressive, risk-taking mentality has often given them an edge, and in a game of this magnitude, they are unlikely to shy away from bold calls on fourth down or trick plays designed to keep LSU off balance. For Ole Miss, the blueprint to victory lies in establishing their tempo early, avoiding costly turnovers, and making LSU play from behind, forcing the Tigers into mistakes under pressure. A win here would not only give the Rebels bragging rights over a perennial SEC powerhouse but also firmly plant them in the playoff discussion, and with talent, momentum, and home-field advantage on their side, Ole Miss believes it can rise to the occasion and deliver a season-defining victory.
1-0 every day. pic.twitter.com/S6K7b1KdR5
— Ole Miss Football (@OleMissFB) September 24, 2025
LSU vs. Ole Miss Prop Picks (AI)
LSU vs. Ole Miss Prediction (AI)

Remi, our AI sports genius, has been pouring over tons of data from every simulation between the Tigers and Rebels and using recursive machine learning and industry leading AI to boil down the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most watching on the linear correlation of emphasis emotional bettors tend to put on LSU’s strength factors between a Tigers team going up against a possibly rested Rebels team. It appears the true game analytics might reflect a slight lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI LSU vs Ole Miss picks, computer picks Tigers vs Rebels, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Tigers Betting Trends
LSU has struggled recently against the spread on the road in SEC play, often finding themselves in closer-than-expected battles due to defensive lapses and inconsistent execution.
Rebels Betting Trends
Ole Miss has been strong against the spread at home, especially in high-profile conference games, covering in a majority of their recent contests thanks to a potent passing attack and timely defensive stops.
Tigers vs. Rebels Matchup Trends
Games between LSU and Ole Miss have historically leaned toward high-scoring affairs, with the over hitting frequently in recent years, and both teams are known for late-game drama that often swings the ATS outcome in the final minutes.
LSU vs. Ole Miss Game Info
What time does LSU vs Ole Miss start on September 27, 2025?
LSU vs Ole Miss starts on September 27, 2025 at 3:30 PM EST.
Where is LSU vs Ole Miss being played?
Venue: Vaught-Hemingway Stadium at Hollingsworth Field.
What are the opening odds for LSU vs Ole Miss?
Spread: Ole Miss -1.5
Moneyline: LSU -105, Ole Miss -115
Over/Under: 54.5
What are the records for LSU vs Ole Miss?
LSU: (4-0) | Ole Miss: (4-0)
What is the AI best bet for LSU vs Ole Miss?
Remi's searched hard and found the best prop for this matchup: Z. Thomas under 29.5 Receiving Yards.. Prices move—always shop for the best number.
What are LSU vs Ole Miss trending bets?
Games between LSU and Ole Miss have historically leaned toward high-scoring affairs, with the over hitting frequently in recent years, and both teams are known for late-game drama that often swings the ATS outcome in the final minutes.
What are LSU trending bets?
LSU trend: LSU has struggled recently against the spread on the road in SEC play, often finding themselves in closer-than-expected battles due to defensive lapses and inconsistent execution.
What are Ole Miss trending bets?
OLEMISS trend: Ole Miss has been strong against the spread at home, especially in high-profile conference games, covering in a majority of their recent contests thanks to a potent passing attack and timely defensive stops.
Where can I find AI Picks for LSU vs Ole Miss?
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
LSU vs. Ole Miss Odds
AI algorithm Remi is pouring through loads of stats on each team. In fact, anytime the LSU vs Ole Miss trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.
LSU vs Ole Miss Opening Odds
LSU Moneyline:
-105 OLEMISS Moneyline: -115
LSU Spread: +1.5
OLEMISS Spread: -1.5
Over/Under: 54.5
LSU vs Ole Miss Live Odds
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Oct 2, 2025 9:00PM EDT
Sam Houston State Bearkats
New Mexico State Aggies
10/2/25 9PM
SAMST
NMEXST
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–
–
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-135
+110
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-2.5 (-110)
+2.5 (-110)
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O 52.5 (-105)
U 52.5 (-115)
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Oct 3, 2025 7:00PM EDT
Western Kentucky Hilltoppers
Delaware Blue Hens
10/3/25 7PM
WKY
DEL
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–
–
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+120
-145
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+2.5 (-102)
-2.5 (-118)
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O 61.5 (-115)
U 61.5 (-105)
|
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Oct 3, 2025 7:00PM EDT
Charlotte 49ers
South Florida Bulls
10/3/25 7PM
CHARLO
SFLA
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–
–
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+1600
-5000
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+27 (-110)
-27 (-110)
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O 54.5 (-115)
U 54.5 (-105)
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Oct 3, 2025 10:00PM EDT
New Mexico Lobos
San Jose State Spartans
10/3/25 10PM
NMEX
SJST
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–
–
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+110
-135
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+2.5 (-110)
-2.5 (-110)
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O 58.5 (-110)
U 58.5 (-110)
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Oct 3, 2025 10:30PM EDT
Colorado State Rams
San Diego State Aztecs
10/3/25 10:30PM
COLOST
SDGST
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–
–
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+200
-250
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+6 (-110)
-6 (-110)
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O 40.5 (-110)
U 40.5 (-110)
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Oct 3, 2025 10:30PM EDT
West Virginia Mountaineers
BYU Cougars
10/3/25 10:30PM
WVU
BYU
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–
–
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+675
-1100
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+18.5 (-105)
-18.5 (-115)
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O 47.5 (-110)
U 47.5 (-110)
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Oct 4, 2025 12:00PM EDT
Ohio Bobcats
Ball State Cardinals
10/4/25 12PM
OHIO
BALLST
|
–
–
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-650
+475
|
-14.5 (-110)
+14.5 (-110)
|
O 51.5 (-105)
U 51.5 (-115)
|
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Oct 4, 2025 12:00PM EDT
Illinois Fighting Illini
Purdue Boilermakers
10/4/25 12PM
ILL
PURDUE
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–
–
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-375
+300
|
-9.5 (-110)
+9.5 (-110)
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O 56.5 (-110)
U 56.5 (-110)
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Oct 4, 2025 12:00PM EDT
Kansas State Wildcats
Baylor Bears
10/4/25 12PM
KSTATE
BAYLOR
|
–
–
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+185
-225
|
+6.5 (-105)
-6.5 (-115)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Kentucky Wildcats
Georgia Bulldogs
10/4/25 12PM
UK
UGA
|
–
–
|
+900
-1600
|
+20.5 (-105)
-20.5 (-115)
|
O 48.5 (-110)
U 48.5 (-110)
|
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Oct 4, 2025 12:00PM EDT
Clemson Tigers
North Carolina Tar Heels
10/4/25 12PM
CLEM
UNC
|
–
–
|
-600
+425
|
-14 (-110)
+14 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
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Oct 4, 2025 12:00PM EDT
Wisconsin Badgers
Michigan Wolverines
10/4/25 12PM
WISC
MICH
|
–
–
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+550
-800
|
+16.5 (-105)
-16.5 (-115)
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O 42.5 (-110)
U 42.5 (-110)
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Oct 4, 2025 12:00PM EDT
Boston College Eagles
Pittsburgh Panthers
10/4/25 12PM
BC
PITT
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–
–
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+200
-250
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+6.5 (-110)
-6.5 (-110)
|
O 58.5 (-110)
U 58.5 (-110)
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Oct 4, 2025 12:00PM EDT
Air Force Falcons
Navy Midshipmen
10/4/25 12PM
AF
NAVY
|
–
–
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+325
-425
|
+11.5 (-110)
-11.5 (-110)
|
O 51.5 (-105)
U 51.5 (-115)
|
|
Oct 4, 2025 12:00PM EDT
Iowa State Cyclones
Cincinnati Bearcats
10/4/25 12PM
IOWAST
CINCY
|
–
–
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+100
-120
|
+1.5 (-110)
-1.5 (-110)
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O 53.5 (-110)
U 53.5 (-110)
|
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Oct 4, 2025 12:00PM EDT
Army Black Knights
UAB Blazers
10/4/25 12PM
ARMY
UAB
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–
–
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-275
+220
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-7 (-110)
+7 (-110)
|
O 57.5 (-110)
U 57.5 (-110)
|
|
Oct 4, 2025 1:00PM EDT
Campbell Fighting Camels
NC State Wolfpack
10/4/25 1PM
CAMP
NCST
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–
–
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+42.5 (-110)
-42.5 (-110)
|
O 61.5 (-110)
U 61.5 (-110)
|
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Oct 4, 2025 1:00PM EDT
Wake Forest Demon Deacons
Virginia Tech Hokies
10/4/25 1PM
WAKE
VATECH
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–
–
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+195
-235
|
+6.5 (-105)
-6.5 (-115)
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O 50.5 (-110)
U 50.5 (-110)
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Oct 4, 2025 1:00PM EDT
UTSA Roadrunners
Temple Owls
10/4/25 1PM
UTSA
TEMPLE
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–
–
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-235
+190
|
-6.5 (-110)
+6.5 (-110)
|
O 56.5 (-115)
U 56.5 (-105)
|
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Oct 4, 2025 2:30PM EDT
Western Michigan Broncos
Umass Minutemen
10/4/25 2:30PM
WMICH
UMASS
|
–
–
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-500
|
-12.5 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
|
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Oct 4, 2025 3:00PM EDT
Oklahoma State Cowboys
Arizona Wildcats
10/4/25 3PM
OKLAST
ARIZ
|
–
–
|
+800
-1400
|
+19.5 (-105)
-19.5 (-115)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Vanderbilt Commodores
Alabama Crimson Tide
10/4/25 3:30PM
VANDY
BAMA
|
–
–
|
+325
-425
|
+10.5 (-110)
-10.5 (-110)
|
O 55.5 (-110)
U 55.5 (-110)
|
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Oct 4, 2025 3:30PM EDT
Eastern Michigan Eagles
Buffalo Bulls
10/4/25 3:30PM
EMICH
BUFF
|
–
–
|
+290
-375
|
+10 (-115)
-10 (-105)
|
O 54.5 (-110)
U 54.5 (-110)
|
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Oct 4, 2025 3:30PM EDT
Washington Huskies
Maryland Terrapins
10/4/25 3:30PM
WASH
MD
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–
–
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-235
+195
|
-6.5 (-110)
+6.5 (-110)
|
O 52.5 (-110)
U 52.5 (-110)
|
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Oct 4, 2025 3:30PM EDT
Miami Ohio Redhawks
Northern Illinois Huskies
10/4/25 3:30PM
MIAOH
NILL
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–
–
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+180
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+5.5 (-112)
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O 38.5 (-110)
U 38.5 (-110)
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Oct 4, 2025 3:30PM EDT
Central Michigan Chippewas
Akron Zips
10/4/25 3:30PM
CMICH
AKRON
|
–
–
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-325
+260
|
-8.5 (-110)
+8.5 (-110)
|
O 45.5 (-115)
U 45.5 (-105)
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Oct 4, 2025 3:30PM EDT
Virginia Cavaliers
Louisville Cardinals
10/4/25 3:30PM
UVA
LVILLE
|
–
–
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+210
-275
|
+7 (-110)
-7 (-110)
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O 61.5 (-110)
U 61.5 (-110)
|
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Oct 4, 2025 3:30PM EDT
UL Monroe Warhawks
Northwestern Wildcats
10/4/25 3:30PM
MONROE
NWEST
|
–
–
|
+325
-425
|
+10.5 (-110)
-10.5 (-110)
|
O 40.5 (-110)
U 40.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
James Madison Dukes
Georgia State Panthers
10/4/25 3:30PM
JMAD
GAST
|
–
–
|
-1400
+800
|
-19.5 (-110)
+19.5 (-110)
|
O 53.5 (-115)
U 53.5 (-105)
|
|
Oct 4, 2025 3:30PM EDT
Syracuse Orange
SMU Mustangs
10/4/25 3:30PM
CUSE
SMU
|
–
–
|
+550
-800
|
+17.5 (-115)
-17.5 (-105)
|
O 58.5 (-110)
U 58.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Boise State Broncos
Notre Dame Fighting Irish
10/4/25 3:30PM
BOISE
ND
|
–
–
|
+800
-1400
|
+20.5 (-110)
-20.5 (-110)
|
O 62.5 (-110)
U 62.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Oregon State Beavers
App State Mountaineers
10/4/25 3:30PM
OREGST
APPST
|
–
–
|
-105
|
+1.5 (-118)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
FIU Panthers
UConn Huskies
10/4/25 3:30PM
FIU
UCONN
|
–
–
|
-300
|
-7.5 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Penn State Nittany Lions
UCLA Bruins
10/4/25 3:30PM
PSU
UCLA
|
–
–
|
-3000
+1300
|
-25.5 (-110)
+25.5 (-110)
|
O 50.5 (-105)
U 50.5 (-115)
|
|
Oct 4, 2025 3:30PM EDT
Texas Longhorns
Florida Gators
10/4/25 3:30PM
TEXAS
FLA
|
–
–
|
-250
+200
|
-7 (-105)
+7 (-115)
|
O 41.5 (-115)
U 41.5 (-105)
|
|
Oct 4, 2025 4:00PM EDT
Kent State Golden Flashes
Oklahoma Sooners
10/4/25 4PM
KENT
OKLA
|
–
–
|
|
+45.5 (-110)
-45.5 (-110)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
Oct 4, 2025 4:00PM EDT
Michigan State Spartans
Nebraska Cornhuskers
10/4/25 4PM
MICHST
NEB
|
–
–
|
+350
-450
|
+11.5 (-110)
-11.5 (-110)
|
O 49.5 (-105)
U 49.5 (-115)
|
|
Oct 4, 2025 4:00PM EDT
Texas State Bobcats
Arkansas State Red Wolves
10/4/25 4PM
TEXST
ARKST
|
–
–
|
-500
+375
|
-13.5 (-110)
+13.5 (-110)
|
O 64.5 (-105)
U 64.5 (-115)
|
|
Oct 4, 2025 6:00PM EDT
Coastal Carolina Chanticleers
Old Dominion Monarchs
10/4/25 6PM
COAST
OLDDOM
|
–
–
|
+675
-1100
|
+18.5 (-110)
-18.5 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 4, 2025 7:00PM EDT
UNLV Rebels
Wyoming Cowboys
10/4/25 7PM
UNLV
WYO
|
–
–
|
-175
+145
|
-3.5 (-110)
+3.5 (-110)
|
O 52.5 (-105)
U 52.5 (-115)
|
|
Oct 4, 2025 7:00PM EDT
Texas Tech Red Raiders
Houston Cougars
10/4/25 7PM
TXTECH
HOU
|
–
–
|
-500
+375
|
-12.5 (-110)
+12.5 (-110)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
Oct 4, 2025 7:00PM EDT
South Alabama Jaguars
Troy Trojans
10/4/25 7PM
SBAMA
TROY
|
–
–
|
+120
-145
|
+2.5 (-105)
-2.5 (-115)
|
O 47.5 (-105)
U 47.5 (-115)
|
|
Oct 4, 2025 7:00PM EDT
Florida Atlantic Owls
Rice Owls
10/4/25 7PM
FAU
RICE
|
–
–
|
+170
-210
|
+4.5 (-110)
-4.5 (-110)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
Oct 4, 2025 7:30PM EDT
Minnesota Golden Gophers
Ohio State Buckeyes
10/4/25 7:30PM
MINN
OHIOST
|
–
–
|
+1300
-3000
|
+24 (-110)
-24 (-110)
|
O 44.5 (-110)
U 44.5 (-110)
|
|
Oct 4, 2025 7:30PM EDT
Kansas Jayhawks
UCF Knights
10/4/25 7:30PM
KANSAS
UCF
|
–
–
|
-210
+170
|
-5 (-110)
+5 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 4, 2025 7:30PM EDT
Colorado Buffaloes
TCU Horned Frogs
10/4/25 7:30PM
COLO
TCU
|
–
–
|
+400
-550
|
+13.5 (-105)
-13.5 (-115)
|
O 57.5 (-115)
U 57.5 (-105)
|
|
Oct 4, 2025 7:30PM EDT
Mississippi State Bulldogs
Texas A&M Aggies
10/4/25 7:30PM
MISSST
TEXAM
|
–
–
|
+450
-625
|
+14 (-105)
-14 (-115)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
Oct 4, 2025 7:30PM EDT
Miami Hurricanes
Florida State Seminoles
10/4/25 7:30PM
MIAMI
FSU
|
–
–
|
-190
+155
|
-4.5 (-110)
+4.5 (-110)
|
O 54.5 (-105)
U 54.5 (-115)
|
|
Oct 4, 2025 8:00PM EDT
Tulsa Golden Hurricane
Memphis Tigers
10/4/25 8PM
TULSA
MEMP
|
–
–
|
+800
-1400
|
+20.5 (-110)
-20.5 (-110)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
Oct 4, 2025 9:30PM EDT
Duke Blue Devils
California Golden Bears
10/4/25 9:30PM
DUKE
CAL
|
–
–
|
-145
+120
|
-3 (-105)
+3 (-115)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
Oct 4, 2025 10:30PM EDT
Nevada Wolf Pack
Fresno State Bulldogs
10/4/25 10:30PM
NEVADA
FRESNO
|
–
–
|
+400
-550
|
+13.5 (-105)
-13.5 (-115)
|
O 44.5 (-115)
U 44.5 (-105)
|
|
Oct 11, 2025 3:30PM EDT
Indiana Hoosiers
Oregon Ducks
10/11/25 3:30PM
IND
OREG
|
–
–
|
+315
-410
|
+10.5 (-106)
-10.5 (-114)
|
O 51.5 (-115)
U 51.5 (-105)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers LSU Tigers vs. Ole Miss Rebels on September 27, 2025 at Vaught-Hemingway Stadium at Hollingsworth Field.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
UK@SC | SC -5.5 | 54.8% | 4 | WIN |
WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |
UNC@UCF | UCF -6.5 | 54.4% | 4 | WIN |
ARKST@KENSAW | KENSAW +4.5 | 54.5% | 4 | WIN |
ILL@IND | IND -6 | 53.2% | 3 | WIN |
SELOU@LSU | LSU -47.5 | 55.3% | 5 | LOSS |
TNMART@MIZZST | MIZZST -14.5 | 56.2% | 6 | WIN |
FRESNO@HAWAII | HAWAII +3 | 56.6% | 6 | WIN |
MRSHL@MTSU | MTSU +2.5 | 56.8% | 6 | LOSS |
MICH@NEB | NEB +1.5 | 57.3% | 7 | LOSS |
WASH@WASHST | DENZEL BOSTON UNDER 69.5 RECV YDS | 56.2% | 6 | LOSS |
IOWA@RUT | ANTWAN RAYMOND OVER 0.5 TOUCHDOWNS | 54.4% | 4 | WIN |
GEORGIA@TENN | UNDER 50.5 | 55.5% | 6 | LOSS |
ARK@OLEMISS | MISS -225 | 72.0% | 9 | WIN |
DUKE@TULANE | TULANE -120 | 56.5% | 4 | WIN |
ARK@OLEMISS | MISS -6.5 | 53.9% | 3 | LOSS |
AKRON@UAB | UAB -11 | 54.7% | 4 | LOSS |
UCONN@DEL | DEL +9.5 | 55.0% | 5 | WIN |
APLST@USM | USM +4 | 55.3% | 6 | WIN |
MERIMK@KENSAW | KENSAW -13.5 | 56.2% | 7 | WIN |
UMASS@IOWA | IOWA -34.5 | 56.4% | 7 | WIN |
UMASS@IOWA | JAZIUN PATTERSON UNDER 0.5 RUSH TDS | 54.8% | 4 | WIN |
NMEX@UCLA | NICO IAMALEAVA UNDER 31.5 PASS ATT | 53.4% | 3 | LOSS |
KSTATE@ARIZ | ARIZ +1.5 | 56.1% | 6 | WIN |
BC@MICHST | NICK MARSH OVER 47.5 RCV YDS | 53.6% | 3 | WIN |
ARIZST@MISSST | MISSST +7 | 54.2% | 4 | WIN |
TULSA@NMEXST | NMEXST +3.5 | 56.9% | 6 | WIN |
UCLA@UNLV | OVER 54.5 | 56.2% | 6 | LOSS |
FRESNO@OREGST | FRESNO +1.5 | 54.7% | 4 | WIN |
VANDY@VATECH | VANDY +2.5 | 55.8% | 5 | WIN |
JMAD@LVILLE | LVILLE -14.5 | 54.0% | 3 | LOSS |
TCU@UNC | JOSEPH MANJACK OVER 37.5 RECV YDS | 53.8% | 3 | LOSS |
ND@MIAMI | MIAMI +3 | 55.2% | 6 | WIN |
MISSST@USM | USM +14.5 | 56.0% | 6 | LOSS |
UTAH@UCLA | UCLA +5.5 | 56.2% | 6 | LOSS |
CAL@OREGST | OREGST +1.5 | 55.1% | 5 | LOSS |
FAU@MD | MD -13.5 | 55.2% | 5 | WIN |
GAS@FRESNO | FRESNO +2 | 55.2% | 5 | WIN |
TOLEDO@UK | UK -9.5 | 56.2% | 6 | LOSS |
AUSTPEAY@MTSU | PEAY +12.5 | 56.2% | 6 | WIN |