Kentucky vs South Carolina Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 27)

Updated: 2025-09-20T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Kentucky Wildcats and the South Carolina Gamecocks will clash on September 27, 2025, in a pivotal SEC East matchup that could shape momentum for the midseason stretch. Kentucky will look to lean on its improving offense and strong defensive line, while South Carolina seeks to capitalize on home-field advantage at Williams-Brice Stadium and its own playmaking quarterback.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 27, 2025

Start Time: 7:45 PM EST​

Venue: Williams-Brice Stadium​

Gamecocks Record: (2-2)

Wildcats Record: (2-1)

OPENING ODDS

UK Moneyline: +197

SC Moneyline: -243

UK Spread: +6.5

SC Spread: -6.5

Over/Under: 46.5

UK
Betting Trends

  • Kentucky has struggled in recent road ATS performances within the SEC, often faltering when their offense fails to establish rhythm early in hostile environments.

SC
Betting Trends

  • South Carolina has been more consistent ATS at home, covering in several recent SEC contests thanks to a defense that rises to the occasion under the energy of its fan base.

MATCHUP TRENDS

  • Games between Kentucky and South Carolina have often been tightly contested, with several recent meetings decided by a touchdown or less, and underdog bettors have frequently found value as spreads rarely reflect the rivalry’s close nature.

UK vs. SC
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: D. Dowdell over 38.5 Rushing Yards.

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Kentucky vs South Carolina Prediction & Odds:
Free CFB Betting Insights for 9/27/25

The September 27, 2025, SEC East matchup between the Kentucky Wildcats and the South Carolina Gamecocks promises to be one of the weekend’s most intriguing battles, as both programs enter the game with plenty to prove and the chance to shift the trajectory of their seasons in front of a national audience. Kentucky comes in looking to showcase its growing consistency on both sides of the ball, with an offense that has become more balanced this year thanks to steady quarterback play, improved wide receiver production, and a rushing attack that can grind out tough yards behind an offensive line that has shown growth after some early struggles. The Wildcats have leaned on their defensive front to set the tone, boasting a group that excels at stopping the run and creating pressure, which will be a critical factor against a South Carolina offense that thrives when its quarterback has time to operate and push the ball vertically. For South Carolina, this game represents not only a chance to defend their home turf at Williams-Brice Stadium but also an opportunity to prove that their rebuild is moving in the right direction under a staff that has emphasized grit, creativity, and resiliency. The Gamecocks’ offense has revolved around their ability to spread defenses with quick passes, mix in a downhill running game, and capitalize on explosive plays, but Kentucky’s defense will test their patience by forcing them to sustain drives and avoid mistakes in long-yardage situations. Special teams will also loom large, as both programs have invested in improving kick coverage and field goal reliability, with the potential for a key special teams play to swing momentum in what projects to be a close contest.

Emotion and discipline will factor heavily into the outcome, as this rivalry has produced plenty of heated moments in recent years, and the team that limits penalties and protects the football will likely find itself in position to win late. Third-down execution and red-zone efficiency are two other areas that could decide the contest, as Kentucky has been opportunistic in capitalizing on scoring chances, while South Carolina’s defense has prided itself on forcing opponents into field goals rather than touchdowns. Both coaching staffs are aware of the importance of this matchup for conference positioning, recruiting momentum, and narrative control heading into October, meaning game plans will likely include a few wrinkles designed to catch the opponent off-guard, whether through trick plays, aggressive fourth-down decisions, or defensive schemes meant to disguise coverage and confuse quarterbacks. Ultimately, the outcome may hinge on which team can impose its identity: if Kentucky can establish balance and let its defensive line control the trenches, the Wildcats will be in a strong position to secure a valuable road win; if South Carolina can ignite its passing game, feed off its raucous home crowd, and make Kentucky chase, the Gamecocks will seize the upper hand. With both teams hungry for validation and desperate to keep pace in a competitive SEC East, fans can expect a physical, emotional, and tightly fought contest that will likely go down to the wire.

Kentucky Wildcats CFB Preview

The Kentucky Wildcats enter their September 27, 2025, SEC East clash with the South Carolina Gamecocks as the away team carrying both a chip on their shoulder and the confidence that comes from steady improvement across multiple facets of the game, though they know performing in the electric atmosphere of Williams-Brice Stadium requires composure and execution under pressure. Kentucky’s offensive identity has become more balanced this season, with their quarterback delivering the ball with efficiency to a receiving corps that has shown flashes of big-play ability while still leaning on a running game that thrives on physicality and clock control, and that balance will be critical against a South Carolina defense that has been stingy at home and thrives on feeding off crowd noise. The offensive line, which has improved in both pass protection and run blocking, will face a stern test against a Gamecocks front seven that prides itself on disrupting timing and creating havoc in the backfield, meaning Kentucky’s ability to stay on schedule and avoid long-yardage situations will be a key to their success. Defensively, the Wildcats have built their reputation on toughness at the line of scrimmage, bottling up run games and forcing opponents to become one-dimensional, and that approach will be vital against a South Carolina team that is most dangerous when it can mix tempo and keep defenses guessing with explosive plays through the air.

The Kentucky secondary will need to stay disciplined and avoid breakdowns in coverage, as one or two lapses in a hostile road environment can shift momentum quickly, while the linebackers must maintain gap integrity to avoid giving up chunk plays on the ground. Special teams execution is another critical area for the Wildcats, as road games in the SEC often turn on hidden yardage, and Kentucky cannot afford mistakes in coverage or missed field goals that gift South Carolina momentum. Mentally, the Wildcats know the importance of staying composed, as emotions in rivalry-like divisional matchups often lead to costly penalties, and their staff will stress the need to play clean football while sticking to their identity. Kentucky also understands the stakes in the SEC East, where every game can shape bowl positioning and overall trajectory, and stealing a road win against a tough opponent would not only reinforce their progress but also serve as a statement that they can compete consistently away from Lexington. For the Wildcats, the formula is clear: establish balance early, stay physical in the trenches, limit explosive plays on defense, and execute with discipline in all three phases, because in a game that is likely to be close late, the team that makes fewer mistakes and capitalizes on opportunities will emerge with a victory. If Kentucky can manage the environment, impose their style of play, and respond to adversity with toughness, they will give themselves every chance to walk out of Williams-Brice Stadium with one of their most important wins of the season.

The Kentucky Wildcats and the South Carolina Gamecocks will clash on September 27, 2025, in a pivotal SEC East matchup that could shape momentum for the midseason stretch. Kentucky will look to lean on its improving offense and strong defensive line, while South Carolina seeks to capitalize on home-field advantage at Williams-Brice Stadium and its own playmaking quarterback. Kentucky vs South Carolina AI Prediction: Free CFB Betting Insights for Sep 27. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

South Carolina Gamecocks CFB Preview

The South Carolina Gamecocks approach their September 27, 2025, SEC East battle against the Kentucky Wildcats with the weight of expectation and the energy of Williams-Brice Stadium behind them, knowing that defending home turf is essential not only for conference standings but also for program momentum and fan morale. South Carolina’s identity under the current staff has centered around grit, creativity, and resiliency, and they will lean on those traits heavily against a Kentucky team that has steadily improved and will test them in every phase. Offensively, the Gamecocks thrive when their quarterback is comfortable, able to distribute the ball quickly to a mix of explosive wideouts and steady tight ends while leaning on a rushing attack that softens defenses and creates opportunities for play-action shots downfield, and the challenge will be doing so against a Wildcats defensive front that has made a habit of winning battles in the trenches. The offensive line must hold up in both pass protection and run blocking, as Kentucky’s front seven will look to collapse pockets, stuff running lanes, and force South Carolina into long-yardage situations where their aggressive blitz packages can thrive. Defensively, the Gamecocks have found success at home by limiting explosive plays and using crowd noise to rattle opposing offenses, and against Kentucky’s balanced approach, they will need to maintain discipline in coverage while ensuring their linebackers and safeties stay sound in assignments to prevent the Wildcats from sustaining long, grinding drives. Generating turnovers has been a point of emphasis, and South Carolina knows that a timely interception or forced fumble could swing the game’s momentum and tilt it in their favor.

Special teams will also be critical, as the Gamecocks have traditionally leaned on big returns, strong punting, and reliable kicking to complement their defense and create short fields for the offense, and in a game expected to be close, one big play on special teams could prove decisive. Beyond tactics, South Carolina will draw strength from its home-field advantage, as Williams-Brice Stadium is one of the most electric atmospheres in the SEC, and the roar of the crowd can disrupt Kentucky’s tempo and force communication breakdowns that lead to miscues. Emotion and discipline will both be critical, as the Gamecocks must channel the intensity of the rivalry into smart, mistake-free football rather than penalties or forced plays that give the Wildcats life. For South Carolina, victory will require sticking to their identity: controlling tempo on offense, staying aggressive but disciplined on defense, and letting special teams tilt the field in their favor, all while feeding off the energy of their fans. If they can execute that formula, limit Kentucky’s balance, and finish strong in the fourth quarter, the Gamecocks will give themselves an excellent opportunity to seize a statement win at home, reinforcing their trajectory within the SEC and sending a message that they are ready to be a consistent force in one of college football’s toughest divisions.

Kentucky vs. South Carolina Prop Picks (AI)

AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the Wildcats and Gamecocks play there’s always several intriguing angles to key in on. Not to mention games played at Williams-Brice Stadium in Sep seemingly never follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: D. Dowdell over 38.5 Rushing Yards.

Kentucky vs. South Carolina Prediction (AI)

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Remi, our AI sports wizard, has been pouring over mountains of data from every simulation between the Wildcats and Gamecocks and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.

Remi has been most focused on the unproportionally assigned weight knucklehead sportsbettors tend to put on coaching factors between a Wildcats team going up against a possibly strong Gamecocks team. In reality, the true game analytics appear to reflect a moderate lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Kentucky vs South Carolina picks, computer picks Wildcats vs Gamecocks, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Wildcats Betting Trends

Kentucky has struggled in recent road ATS performances within the SEC, often faltering when their offense fails to establish rhythm early in hostile environments.

Gamecocks Betting Trends

South Carolina has been more consistent ATS at home, covering in several recent SEC contests thanks to a defense that rises to the occasion under the energy of its fan base.

Wildcats vs. Gamecocks Matchup Trends

Games between Kentucky and South Carolina have often been tightly contested, with several recent meetings decided by a touchdown or less, and underdog bettors have frequently found value as spreads rarely reflect the rivalry’s close nature.

Kentucky vs. South Carolina Game Info

Kentucky vs South Carolina starts on September 27, 2025 at 7:45 PM EST.

Venue: Williams-Brice Stadium.

Spread: South Carolina -6.5
Moneyline: Kentucky +197, South Carolina -243
Over/Under: 46.5

Kentucky: (2-1)  |  South Carolina: (2-2)

Remi's searched hard and found the best prop for this matchup: D. Dowdell over 38.5 Rushing Yards.. Prices move—always shop for the best number.

Games between Kentucky and South Carolina have often been tightly contested, with several recent meetings decided by a touchdown or less, and underdog bettors have frequently found value as spreads rarely reflect the rivalry’s close nature.

UK trend: Kentucky has struggled in recent road ATS performances within the SEC, often faltering when their offense fails to establish rhythm early in hostile environments.

SC trend: South Carolina has been more consistent ATS at home, covering in several recent SEC contests thanks to a defense that rises to the occasion under the energy of its fan base.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Kentucky vs. South Carolina Odds

Remi is pouring through loads of data on each line. In fact, anytime the Kentucky vs South Carolina trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable patterns.

Kentucky vs South Carolina Opening Odds

UK Moneyline: +197
SC Moneyline: -243
UK Spread: +6.5
SC Spread: -6.5
Over/Under: 46.5

Kentucky vs South Carolina Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-370
 
-9.5 (-110)
O 55.5 (-110)
U 55.5 (-110)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-108
-108
-1.5 (-105)
+1.5 (-115)
O 51.5 (-110)
U 51.5 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-225
+188
-6.5 (-110)
+6.5 (-110)
O 56.5 (-106)
U 56.5 (-114)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4000
+1500
-27.5 (-102)
+27.5 (-120)
O 60.5 (-115)
U 60.5 (-105)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+160
-190
+4.5 (-110)
-4.5 (-110)
O 50.5 (-105)
U 50.5 (-115)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1800
+980
-21.5 (-105)
+21.5 (-115)
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-285
+230
-7.5 (-105)
+7.5 (-115)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+115
-2.5 (-110)
+2.5 (-110)
O 58.5 (-110)
U 58.5 (-110)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-205
+168
-5.5 (-110)
+5.5 (-110)
O 63.5 (-106)
U 63.5 (-114)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1600
-4500
+25.5 (-110)
-25.5 (-110)
O 54.5 (-115)
U 54.5 (-105)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+230
-285
+7.5 (-118)
-7.5 (-104)
O 42.5 (-120)
U 42.5 (-102)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-450
+340
-12.5 (-110)
+12.5 (-110)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-170
+140
-3.5 (-108)
+3.5 (-112)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+610
-950
+17.5 (-115)
-17.5 (-105)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-610
 
-14.5 (-105)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+172
-210
+4.5 (-105)
-4.5 (-115)
O 54.5 (-105)
U 54.5 (-115)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+122
-146
+2.5 (+100)
-2.5 (-122)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
-110
-110
+1.5 (-115)
-1.5 (-105)
O 57.5 (-105)
U 57.5 (-115)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+290
-375
+9.5 (-102)
-9.5 (-120)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-400
+310
-10.5 (-110)
+10.5 (-110)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+122
-146
+2.5 (-102)
-2.5 (-120)
O 61.5 (-110)
U 61.5 (-110)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+275
-350
+8.5 (-110)
-8.5 (-110)
O 38.5 (-115)
U 38.5 (-105)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-520
+385
-11.5 (-118)
+11.5 (-104)
O 47.5 (-105)
U 47.5 (-115)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+122
-146
+2.5 (+100)
-2.5 (-122)
O 48.5 (-115)
U 48.5 (-105)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-225
+188
-5.5 (-120)
+5.5 (-102)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+176
-215
+5.5 (-110)
-5.5 (-110)
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
+104
-125
+1.5 (-105)
-1.5 (-115)
O 46.5 (-114)
U 46.5 (-106)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+480
-670
+15.5 (-110)
-15.5 (-110)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+146
-176
+4.5 (-115)
-4.5 (-105)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-720
 
-15.5 (-115)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-146
+122
-2.5 (-122)
+2.5 (+100)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+115
-138
+2.5 (-106)
-2.5 (-114)
O 52.5 (-110)
U 52.5 (-110)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+195
-240
+6.5 (-110)
-6.5 (-110)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+106
 
+2.5 (-115)
 
O 41.5 (-110)
U 41.5 (-110)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+310
 
+11.5 (-115)
 
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+2800
-10000
+37.5 (-108)
-37.5 (-112)
O 56.5 (-105)
U 56.5 (-115)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+152
-184
+4.5 (-115)
-4.5 (-105)
O 67.5 (-105)
U 67.5 (-115)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-285
+230
-7.5 (-102)
+7.5 (-120)
O 44.5 (-120)
U 44.5 (-102)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-670
+470
-15.5 (-112)
+15.5 (-108)
O 55.5 (-106)
U 55.5 (-114)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-106)
-33.5 (-114)
O 44.5 (-108)
U 44.5 (-112)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+270
-345
+9.5 (-110)
-9.5 (-110)
O 47.5 (-112)
U 47.5 (-108)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30.5 (-115)
-30.5 (-105)
O 45.5 (-104)
U 45.5 (-118)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+106
-128
+1.5 (-105)
-1.5 (-115)
O 63.5 (-105)
U 63.5 (-115)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-630
+450
-14.5 (-105)
+14.5 (-115)
O 48.5 (-105)
U 48.5 (-115)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-144
+120
-2.5 (-120)
+2.5 (-102)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1600
-4500
+25.5 (-110)
-25.5 (-110)
O 55.5 (-104)
U 55.5 (-118)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+184
-225
+5.5 (-104)
-5.5 (-118)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-345
+270
-9.5 (-110)
+9.5 (-110)
O 53.5 (-118)
U 53.5 (-104)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+220
-275
+7.5 (-120)
-7.5 (-102)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+375
-500
+13.5 (-110)
-13.5 (-110)
O 49.5 (-115)
U 49.5 (-105)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Kentucky Wildcats vs. South Carolina Gamecocks on September 27, 2025 at Williams-Brice Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN