Hoosiers vs. Hawkeyes
Prediction, Odds & Props
Sep 27 | CFB AI Picks
Updated: 2025-09-20T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The Indiana Hoosiers will travel to Kinnick Stadium to take on the Iowa Hawkeyes on September 27, 2025, in a Big Ten showdown that pits Indiana’s improving offense against Iowa’s traditionally stout defense. Both teams are looking for a conference win to build momentum, with Iowa seeking to protect its home field while Indiana aims to prove it can compete on the road against one of the league’s most disciplined programs.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Sep 27, 2025
Start Time: 3:30 PM EST
Venue: Kinnick Stadium
Hawkeyes Record: (3-1)
Hoosiers Record: (4-0)
OPENING ODDS
IND Moneyline: -299
IOWA Moneyline: +238
IND Spread: -7.5
IOWA Spread: +7.5
Over/Under: 48.5
IND
Betting Trends
- Indiana has struggled to cover spreads consistently in Big Ten road games, often falling behind early and failing to recover against physical opponents.
IOWA
Betting Trends
- Iowa has been solid ATS at home, especially in defensive-driven games where their ability to limit opponents and control tempo has paid off.
MATCHUP TRENDS
- Historically, matchups between these two teams have leaned toward the under, as Iowa’s defense and methodical pace often suppress scoring while Indiana’s offense has struggled to break through in Iowa City.
IND vs. IOWA
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: M. Gronowski under 37.5 Rushing Yards.
LIVE CFB ODDS
CFB ODDS COMPARISON
WANT MORE AI PICKS?
VS. SPREAD
310-227
NET UNITS
(INCL VIG)
+390.9
NET PROFIT
(INCL VIG)
$100/UNIT
$39,086
VS. SPREAD
1564-1335
NET UNITS
(INCL VIG)
+387.3
NET PROFIT
(INCL VIG)
$100/UNIT
$38,728
AI SPORTS PICK PRODUCTS
Create a Free Account

Remi Finds New Picks

Remi Works 24/7
Remi uses this probability to assign units to each pick.
Get Remi's AI Picks
Get Remi’s Top AI Sports Picks sent direct to your inbox.
Hedge Meaning in Betting | 4 Obvious Times to Hedge
Learn about hedge betting to manage risk and secure profits. Understand...
What is a Push in Betting? | 3 Ways To Use To Your Advantage
Understand what a push in betting means, how it happens in...
What Does the + and – Mean in Sports Betting? | 5 Easy Tips
Learn the basics of sports betting odds, what the plus (+)...
Indiana vs Iowa Prediction & Odds:
Free CFB Betting Insights for 9/27/25
The Hawkeyes’ offensive line, long a strength of the program, will look to impose its will against Indiana’s defensive front, and if they can control the trenches, Iowa will dictate tempo, shorten the game, and wear down a Hoosiers defense that has struggled at times with depth. Indiana’s defense, meanwhile, will need to be opportunistic, generating negative plays and hoping to force Iowa’s offense into long-yardage situations where their lack of explosive firepower can be exposed, though doing so consistently against Iowa’s disciplined scheme will be difficult. Special teams could play an outsized role in this matchup, as Iowa’s kicking game and punting have historically been among the best in the nation, and field position could dictate scoring opportunities in what projects as a low-possession, grind-it-out game. The atmosphere at Kinnick Stadium will only magnify the challenge for Indiana, as the Hawkeyes’ home field is one of the most intimidating in the Big Ten, with a raucous crowd capable of disrupting communication and adding to the pressure on the visiting offense. Both coaching staffs will stress discipline and execution, knowing that turnovers and penalties in a game like this can swing momentum dramatically, and the battle of patience—between Indiana’s desire to generate offense and Iowa’s willingness to trust its defense and grind away—will define the narrative. Ultimately, this contest projects as another installment in Iowa’s familiar formula of defense, field position, and efficiency against an Indiana team searching for consistency, and whichever side can control the trenches and win critical third-down battles is likely to emerge with a win that carries significant weight for their Big Ten campaigns.
On to our first business trip of 2025. pic.twitter.com/xx0lj7wSYz
— Indiana Football (@IndianaFootball) September 23, 2025
Indiana Hoosiers CFB Preview
The Indiana Hoosiers will enter their September 27, 2025, showdown at Kinnick Stadium knowing full well the challenge that awaits them, as winning on the road against Iowa requires both composure and execution, two qualities that have often eluded Indiana in recent Big Ten road trips. Offensively, the Hoosiers come into the game hoping to showcase the progress they’ve made under their current staff, with a quarterback who has steadily grown into his role, delivering accurate short-to-intermediate throws and occasionally taking shots downfield to keep defenses honest. His ability to protect the football will be crucial, as Iowa’s opportunistic defense has made a reputation out of turning careless passes into game-changing interceptions. Indiana’s receivers, while not as physically imposing as some of their conference counterparts, have shown the ability to find soft spots in zone coverage, and they will need to get open quickly given the relentless pressure Iowa’s front seven is likely to bring. The Hoosiers’ running game has been serviceable, leaning on a committee of backs who can churn out tough yards, but the offensive line has been inconsistent, sometimes struggling against aggressive defensive fronts, and that unit will face one of its toughest tests against an Iowa front built to win battles in the trenches. Defensively, Indiana will look to counter Iowa’s physical offensive style by stacking the box and relying on linebackers to fill gaps quickly, as slowing down the Hawkeyes’ rushing attack is critical to forcing them into uncomfortable passing situations where they are less effective.
The Hoosiers’ secondary will be tested not by volume but by precision, as Iowa quarterbacks thrive in play-action situations and targeting tight ends in mismatches, and discipline in coverage will be a must to avoid giving up back-breaking completions. On special teams, Indiana knows it cannot afford miscues, as field position will be paramount in a low-possession game, and a missed assignment on coverage or a missed field goal could tilt momentum irreversibly toward the Hawkeyes. More broadly, Indiana’s challenge will be mental as much as physical, as Kinnick Stadium is one of the most hostile environments in the Big Ten, and past Hoosier teams have faltered under that pressure, making it vital for this group to establish confidence early and avoid falling behind. The coaching staff will likely look to open the game with scripted plays designed to establish rhythm and settle nerves, while leaning on defensive aggressiveness to generate a turnover or two that could swing momentum. For Indiana, the path to victory is narrow but clear: protect the football, sustain drives with a balanced offensive approach, and force Iowa to abandon its comfort zone by creating long-yardage scenarios. If they can execute this formula while avoiding self-inflicted mistakes, the Hoosiers have a chance to be competitive deep into the fourth quarter, but if the offense sputters or turnovers pile up, it could quickly turn into another long afternoon in Iowa City that highlights the gap Indiana still needs to close to consistently compete in the Big Ten.

Credit: USA TODAY/IMAGN
Iowa Hawkeyes CFB Preview
The Iowa Hawkeyes will host the Indiana Hoosiers on September 27, 2025, at Kinnick Stadium with confidence in their tried-and-true formula of stingy defense, physicality, and home-field advantage, knowing that their brand of football has historically worn down opponents like Indiana who struggle to match their consistency in the trenches. Offensively, Iowa will look to establish its identity early by pounding the ball behind one of the most reliable offensive lines in the Big Ten, featuring road graders who open lanes for a stable of running backs capable of grinding out tough yards between the tackles and breaking the occasional run into the secondary. Their quarterback will be tasked with managing the game, making efficient throws on third down, and leveraging play-action opportunities that take advantage of defenses creeping up to stop the run, with tight ends often serving as the go-to weapons in Iowa’s passing attack. The wide receivers, while not typically explosive, are reliable enough to keep drives alive, and their ability to stretch the field just enough prevents defenses from fully keying on the run. Defensively, Iowa remains one of the nation’s most disciplined units, with a front seven that thrives on shutting down rushing lanes and linebackers who diagnose plays quickly and swarm to the football, while the secondary has developed a reputation for turning over even the most polished quarterbacks through sound coverage and ball-hawking instincts.
That opportunistic style will be critical against Indiana, whose quarterback has shown improvement but remains vulnerable to mistakes when pressured. On special teams, Iowa enjoys one of the strongest advantages in college football, with consistently strong punting, reliable kicking, and coverage units that flip field position and put pressure on opposing offenses to drive long fields, something Indiana has struggled with historically. The intangible edge of playing at Kinnick Stadium, where the crowd is both intimidating and disruptive, further tilts the balance in Iowa’s favor, as visiting teams often struggle to maintain communication and composure under the relentless noise and atmosphere. The coaching staff will emphasize patience and discipline, understanding that their defense and special teams are capable of dictating tempo even if the offense is not putting up gaudy numbers, and their strategy will likely revolve around wearing Indiana down physically and capitalizing on mistakes. For Iowa, the path to victory involves playing to their strengths: run the football effectively, dominate time of possession, prevent Indiana from generating explosive plays, and rely on their defense to create turnovers that shorten the field. If they succeed in executing that game plan, the Hawkeyes not only stand an excellent chance of defeating Indiana but also of reinforcing their position as one of the Big Ten’s most consistent and dangerous programs, particularly at home where their style of play becomes even more suffocating.
Week Five Captains. pic.twitter.com/dMkFDNlCSg
— Hawkeye Football (@HawkeyeFootball) September 23, 2025
Indiana vs. Iowa Prop Picks (AI)
Indiana vs. Iowa Prediction (AI)

Remi, our AI sports algorithm, has been pouring over millions of data from every angle between the Hoosiers and Hawkeyes and using recursive machine learning and impressive AI to crunch the data to a single cover probability.
Remi has been most fixated on the linear correlation of emphasis knucklehead sportsbettors regularly put on coaching factors between a Hoosiers team going up against a possibly unhealthy Hawkeyes team. In reality, the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI Indiana vs Iowa picks, computer picks Hoosiers vs Hawkeyes, best bets, model edges, confidence ratings.
![]() |
DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
ACTIVE PICKS LOCKED - SEE NOW |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
Hoosiers Betting Trends
Indiana has struggled to cover spreads consistently in Big Ten road games, often falling behind early and failing to recover against physical opponents.
Hawkeyes Betting Trends
Iowa has been solid ATS at home, especially in defensive-driven games where their ability to limit opponents and control tempo has paid off.
Hoosiers vs. Hawkeyes Matchup Trends
Historically, matchups between these two teams have leaned toward the under, as Iowa’s defense and methodical pace often suppress scoring while Indiana’s offense has struggled to break through in Iowa City.
Indiana vs. Iowa Game Info
What time does Indiana vs Iowa start on September 27, 2025?
Indiana vs Iowa starts on September 27, 2025 at 3:30 PM EST.
Where is Indiana vs Iowa being played?
Venue: Kinnick Stadium.
What are the opening odds for Indiana vs Iowa?
Spread: Iowa +7.5
Moneyline: Indiana -299, Iowa +238
Over/Under: 48.5
What are the records for Indiana vs Iowa?
Indiana: (4-0) | Iowa: (3-1)
What is the AI best bet for Indiana vs Iowa?
Remi's searched hard and found the best prop for this matchup: M. Gronowski under 37.5 Rushing Yards.. Prices move—always shop for the best number.
What are Indiana vs Iowa trending bets?
Historically, matchups between these two teams have leaned toward the under, as Iowa’s defense and methodical pace often suppress scoring while Indiana’s offense has struggled to break through in Iowa City.
What are Indiana trending bets?
IND trend: Indiana has struggled to cover spreads consistently in Big Ten road games, often falling behind early and failing to recover against physical opponents.
What are Iowa trending bets?
IOWA trend: Iowa has been solid ATS at home, especially in defensive-driven games where their ability to limit opponents and control tempo has paid off.
Where can I find AI Picks for Indiana vs Iowa?
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
Indiana vs. Iowa Odds
Remi is pouring through loads of data on each team. In fact, anytime the Indiana vs Iowa trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable patterns.
Indiana vs Iowa Opening Odds
IND Moneyline:
-299 IOWA Moneyline: +238
IND Spread: -7.5
IOWA Spread: +7.5
Over/Under: 48.5
Indiana vs Iowa Live Odds
Games | PTS | ML | SPR | O/U | |
---|---|---|---|---|---|
Oct 2, 2025 9:00PM EDT
Sam Houston State Bearkats
New Mexico State Aggies
10/2/25 9PM
SAMST
NMEXST
|
–
–
|
-134
+112
|
-2.5 (-110)
+2.5 (-110)
|
O 53.5 (-115)
U 53.5 (-105)
|
|
Oct 3, 2025 7:00PM EDT
Western Kentucky Hilltoppers
Delaware Blue Hens
10/3/25 7PM
WKY
DEL
|
–
–
|
+118
-142
|
+2.5 (-105)
-2.5 (-115)
|
O 61.5 (-105)
U 61.5 (-115)
|
|
Oct 3, 2025 7:00PM EDT
Charlotte 49ers
South Florida Bulls
10/3/25 7PM
CHARLO
SFLA
|
–
–
|
+2000
-7000
|
+27.5 (-102)
-27.5 (-120)
|
O 55.5 (-106)
U 55.5 (-114)
|
|
Oct 3, 2025 10:00PM EDT
New Mexico Lobos
San Jose State Spartans
10/3/25 10PM
NMEX
SJST
|
–
–
|
+114
-137
|
+2.5 (-108)
-2.5 (-112)
|
O 58.5 (-105)
U 58.5 (-115)
|
|
Oct 3, 2025 10:30PM EDT
Colorado State Rams
San Diego State Aztecs
10/3/25 10:30PM
COLOST
SDGST
|
–
–
|
+190
-235
|
+5.5 (+100)
-5.5 (-122)
|
O 40.5 (-115)
U 40.5 (-105)
|
|
Oct 3, 2025 10:30PM EDT
West Virginia Mountaineers
BYU Cougars
10/3/25 10:30PM
WVU
BYU
|
–
–
|
+860
-1600
|
+18.5 (-104)
-18.5 (-118)
|
O 47.5 (-105)
U 47.5 (-115)
|
|
Oct 4, 2025 12:00PM EDT
Ohio Bobcats
Ball State Cardinals
10/4/25 12PM
OHIO
BALLST
|
–
–
|
-630
+450
|
-14.5 (-110)
+14.5 (-110)
|
O 51.5 (-105)
U 51.5 (-115)
|
|
Oct 4, 2025 12:00PM EDT
Illinois Fighting Illini
Purdue Boilermakers
10/4/25 12PM
ILL
PURDUE
|
–
–
|
-385
+300
|
-9.5 (-118)
+9.5 (-104)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Kansas State Wildcats
Baylor Bears
10/4/25 12PM
KSTATE
BAYLOR
|
–
–
|
+190
-235
|
+6.5 (-108)
-6.5 (-112)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Kentucky Wildcats
Georgia Bulldogs
10/4/25 12PM
UK
UGA
|
–
–
|
+890
-1700
|
+20.5 (-110)
-20.5 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Clemson Tigers
North Carolina Tar Heels
10/4/25 12PM
CLEM
UNC
|
–
–
|
-800
+540
|
-14.5 (-118)
+14.5 (-104)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Wisconsin Badgers
Michigan Wolverines
10/4/25 12PM
WISC
MICH
|
–
–
|
+660
-1050
|
+16.5 (+102)
-16.5 (-124)
|
O 43.5 (-110)
U 43.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Boston College Eagles
Pittsburgh Panthers
10/4/25 12PM
BC
PITT
|
–
–
|
+180
-220
|
+5.5 (-105)
-5.5 (-115)
|
O 58.5 (-110)
U 58.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Air Force Falcons
Navy Midshipmen
10/4/25 12PM
AF
NAVY
|
–
–
|
+340
-450
|
+11.5 (-105)
-11.5 (-115)
|
O 51.5 (-115)
U 51.5 (-105)
|
|
Oct 4, 2025 12:00PM EDT
Iowa State Cyclones
Cincinnati Bearcats
10/4/25 12PM
IOWAST
CINCY
|
–
–
|
+105
-126
|
+1.5 (-105)
-1.5 (-115)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
Oct 4, 2025 12:00PM EDT
Army Black Knights
UAB Blazers
10/4/25 12PM
ARMY
UAB
|
–
–
|
-265
+215
|
-7.5 (-102)
+7.5 (-120)
|
O 57.5 (-110)
U 57.5 (-110)
|
|
Oct 4, 2025 1:00PM EDT
Campbell Fighting Camels
NC State Wolfpack
10/4/25 1PM
CAMP
NCST
|
–
–
|
|
+42.5 (-110)
-42.5 (-110)
|
O 61.5 (-110)
U 61.5 (-110)
|
|
Oct 4, 2025 1:00PM EDT
Wake Forest Demon Deacons
Virginia Tech Hokies
10/4/25 1PM
WAKE
VATECH
|
–
–
|
+198
-245
|
+6.5 (-104)
-6.5 (-118)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
Oct 4, 2025 1:00PM EDT
UTSA Roadrunners
Temple Owls
10/4/25 1PM
UTSA
TEMPLE
|
–
–
|
-235
+195
|
-6.5 (-110)
+6.5 (-110)
|
O 58.5 (-115)
U 58.5 (-105)
|
|
Oct 4, 2025 2:30PM EDT
Western Michigan Broncos
Umass Minutemen
10/4/25 2:30PM
WMICH
UMASS
|
–
–
|
-600
|
-13.5 (-115)
|
O 47.5 (-105)
U 47.5 (-115)
|
|
Oct 4, 2025 3:00PM EDT
Oklahoma State Cowboys
Arizona Wildcats
10/4/25 3PM
OKLAST
ARIZ
|
–
–
|
+680
-1200
|
+20.5 (-115)
-20.5 (-105)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Vanderbilt Commodores
Alabama Crimson Tide
10/4/25 3:30PM
VANDY
BAMA
|
–
–
|
+330
-430
|
+10.5 (-105)
-10.5 (-115)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Eastern Michigan Eagles
Buffalo Bulls
10/4/25 3:30PM
EMICH
BUFF
|
–
–
|
+285
-365
|
+10.5 (-118)
-10.5 (-104)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Washington Huskies
Maryland Terrapins
10/4/25 3:30PM
WASH
MD
|
–
–
|
-250
+202
|
-6.5 (-114)
+6.5 (-106)
|
O 53.5 (-115)
U 53.5 (-105)
|
|
Oct 4, 2025 3:30PM EDT
Miami Ohio Redhawks
Northern Illinois Huskies
10/4/25 3:30PM
MIAOH
NILL
|
–
–
|
+168
|
+5.5 (-112)
|
O 37.5 (-114)
U 37.5 (-106)
|
|
Oct 4, 2025 3:30PM EDT
Central Michigan Chippewas
Akron Zips
10/4/25 3:30PM
CMICH
AKRON
|
–
–
|
-330
+260
|
-8.5 (-110)
+8.5 (-110)
|
O 45.5 (-105)
U 45.5 (-115)
|
|
Oct 4, 2025 3:30PM EDT
Virginia Cavaliers
Louisville Cardinals
10/4/25 3:30PM
UVA
LVILLE
|
–
–
|
+195
-240
|
+6.5 (-105)
-6.5 (-115)
|
O 62.5 (-102)
U 62.5 (-120)
|
|
Oct 4, 2025 3:30PM EDT
UL Monroe Warhawks
Northwestern Wildcats
10/4/25 3:30PM
MONROE
NWEST
|
–
–
|
+350
-465
|
+10.5 (-104)
-10.5 (-118)
|
O 40.5 (-110)
U 40.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
James Madison Dukes
Georgia State Panthers
10/4/25 3:30PM
JMAD
GAST
|
–
–
|
-1200
+720
|
-19.5 (-115)
+19.5 (-105)
|
O 53.5 (-115)
U 53.5 (-105)
|
|
Oct 4, 2025 3:30PM EDT
Syracuse Orange
SMU Mustangs
10/4/25 3:30PM
CUSE
SMU
|
–
–
|
+550
-820
|
+17.5 (-118)
-17.5 (-104)
|
O 58.5 (-105)
U 58.5 (-115)
|
|
Oct 4, 2025 3:30PM EDT
Boise State Broncos
Notre Dame Fighting Irish
10/4/25 3:30PM
BOISE
ND
|
–
–
|
+760
-1300
|
+20.5 (-110)
-20.5 (-110)
|
O 62.5 (-110)
U 62.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Oregon State Beavers
App State Mountaineers
10/4/25 3:30PM
OREGST
APPST
|
–
–
|
+105
|
+1.5 (-105)
|
O 53.5 (-110)
U 53.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
FIU Panthers
UConn Huskies
10/4/25 3:30PM
FIU
UCONN
|
–
–
|
-265
|
-7.5 (-105)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 4, 2025 3:30PM EDT
Penn State Nittany Lions
UCLA Bruins
10/4/25 3:30PM
PSU
UCLA
|
–
–
|
-4000
+1400
|
-24.5 (-115)
+24.5 (-105)
|
O 50.5 (-106)
U 50.5 (-114)
|
|
Oct 4, 2025 3:30PM EDT
Texas Longhorns
Florida Gators
10/4/25 3:30PM
TEXAS
FLA
|
–
–
|
-275
+220
|
-6.5 (-122)
+6.5 (+100)
|
O 41.5 (-110)
U 41.5 (-110)
|
|
Oct 4, 2025 4:00PM EDT
Kent State Golden Flashes
Oklahoma Sooners
10/4/25 4PM
KENT
OKLA
|
–
–
|
|
+45.5 (-110)
-45.5 (-110)
|
O 53.5 (-115)
U 53.5 (-105)
|
|
Oct 4, 2025 4:00PM EDT
Michigan State Spartans
Nebraska Cornhuskers
10/4/25 4PM
MICHST
NEB
|
–
–
|
+350
-465
|
+10.5 (-105)
-10.5 (-115)
|
O 48.5 (-115)
U 48.5 (-105)
|
|
Oct 4, 2025 4:00PM EDT
Texas State Bobcats
Arkansas State Red Wolves
10/4/25 4PM
TEXST
ARKST
|
–
–
|
-500
+375
|
-13.5 (-110)
+13.5 (-110)
|
O 64.5 (-104)
U 64.5 (-118)
|
|
Oct 4, 2025 6:00PM EDT
Coastal Carolina Chanticleers
Old Dominion Monarchs
10/4/25 6PM
COAST
OLDDOM
|
–
–
|
+860
-1600
|
+20.5 (-106)
-20.5 (-114)
|
O 54.5 (-115)
U 54.5 (-105)
|
|
Oct 4, 2025 7:00PM EDT
UNLV Rebels
Wyoming Cowboys
10/4/25 7PM
UNLV
WYO
|
–
–
|
-166
+138
|
-3.5 (-110)
+3.5 (-110)
|
O 50.5 (-110)
U 50.5 (-110)
|
|
Oct 4, 2025 7:00PM EDT
Texas Tech Red Raiders
Houston Cougars
10/4/25 7PM
TXTECH
HOU
|
–
–
|
-420
+320
|
-10.5 (-112)
+10.5 (-108)
|
O 51.5 (-110)
U 51.5 (-110)
|
|
Oct 4, 2025 7:00PM EDT
South Alabama Jaguars
Troy Trojans
10/4/25 7PM
SBAMA
TROY
|
–
–
|
+108
-130
|
+2.5 (-110)
-2.5 (-110)
|
O 46.5 (-114)
U 46.5 (-106)
|
|
Oct 4, 2025 7:00PM EDT
Florida Atlantic Owls
Rice Owls
10/4/25 7PM
FAU
RICE
|
–
–
|
+150
-182
|
+4.5 (-112)
-4.5 (-108)
|
O 53.5 (-115)
U 53.5 (-105)
|
|
Oct 4, 2025 7:30PM EDT
Minnesota Golden Gophers
Ohio State Buckeyes
10/4/25 7:30PM
MINN
OHIOST
|
–
–
|
+1280
-3500
|
+23.5 (-110)
-23.5 (-110)
|
O 44.5 (-105)
U 44.5 (-115)
|
|
Oct 4, 2025 7:30PM EDT
Kansas Jayhawks
UCF Knights
10/4/25 7:30PM
KANSAS
UCF
|
–
–
|
-205
+168
|
-5.5 (-110)
+5.5 (-110)
|
O 54.5 (-110)
U 54.5 (-110)
|
|
Oct 4, 2025 7:30PM EDT
Colorado Buffaloes
TCU Horned Frogs
10/4/25 7:30PM
COLO
TCU
|
–
–
|
+400
-550
|
+13.5 (-104)
-13.5 (-118)
|
O 57.5 (-110)
U 57.5 (-110)
|
|
Oct 4, 2025 7:30PM EDT
Mississippi State Bulldogs
Texas A&M Aggies
10/4/25 7:30PM
MISSST
TEXAM
|
–
–
|
+470
-670
|
+14.5 (-114)
-14.5 (-106)
|
O 55.5 (-110)
U 55.5 (-110)
|
|
Oct 4, 2025 7:30PM EDT
Miami Hurricanes
Florida State Seminoles
10/4/25 7:30PM
MIAMI
FSU
|
–
–
|
-184
+150
|
-4.5 (-106)
+4.5 (-114)
|
O 53.5 (-115)
U 53.5 (-105)
|
|
Oct 4, 2025 8:00PM EDT
Tulsa Golden Hurricane
Memphis Tigers
10/4/25 8PM
TULSA
MEMP
|
–
–
|
+800
-1400
|
+20.5 (-114)
-20.5 (-106)
|
O 56.5 (-110)
U 56.5 (-110)
|
|
Oct 4, 2025 9:30PM EDT
Duke Blue Devils
California Golden Bears
10/4/25 9:30PM
DUKE
CAL
|
–
–
|
-155
+130
|
-3 (-110)
+3 (-110)
|
O 57.5 (-110)
U 57.5 (-110)
|
|
Oct 4, 2025 10:30PM EDT
Nevada Wolf Pack
Fresno State Bulldogs
10/4/25 10:30PM
NEVADA
FRESNO
|
–
–
|
+440
-610
|
+13.5 (-102)
-13.5 (-120)
|
O 44.5 (-115)
U 44.5 (-105)
|
|
Oct 9, 2025 7:30PM EDT
East Carolina Pirates
Tulane Green Wave
10/9/25 7:30PM
ECAR
TULANE
|
–
–
|
|
+7 (-110)
-7 (-110)
|
|
|
Oct 10, 2025 7:30PM EDT
South Florida Bulls
North Texas Mean Green
10/10/25 7:30PM
SFLA
NOTEX
|
–
–
|
|
+2.5 (-110)
-2.5 (-110)
|
|
|
Oct 11, 2025 12:00PM EDT
Florida Gators
Texas A&M Aggies
10/11/25 12PM
FLA
TEXAM
|
–
–
|
|
+9.5 (-110)
-9.5 (-110)
|
|
|
Oct 11, 2025 12:00PM EDT
Alabama Crimson Tide
Missouri Tigers
10/11/25 12PM
BAMA
MIZZOU
|
–
–
|
-205
+168
|
-6.5 (-102)
+6.5 (-120)
|
O 55.5 (-108)
U 55.5 (-112)
|
|
Oct 11, 2025 12:00PM EDT
Ohio State Buckeyes
Illinois Fighting Illini
10/11/25 12PM
OHIOST
ILL
|
–
–
|
-780
+530
|
-15.5 (-110)
+15.5 (-110)
|
O 50.5 (-105)
U 50.5 (-115)
|
|
Oct 11, 2025 12:45PM EDT
Georgia Bulldogs
Auburn Tigers
10/11/25 12:45PM
UGA
AUBURN
|
–
–
|
-172
+142
|
-3.5 (-114)
+3.5 (-106)
|
O 47.5 (-110)
U 47.5 (-110)
|
|
Oct 11, 2025 3:30PM EDT
Indiana Hoosiers
Oregon Ducks
10/11/25 3:30PM
IND
OREG
|
–
–
|
+300
-385
|
+10.5 (-112)
-10.5 (-108)
|
O 52.5 (-110)
U 52.5 (-110)
|
|
Oct 11, 2025 3:30PM EDT
Oklahoma Sooners
Texas Longhorns
10/11/25 3:30PM
OKLA
TEXAS
|
–
–
|
|
+3.5 (-110)
-3.5 (-110)
|
|
|
Oct 11, 2025 4:15PM EDT
Arkansas Razorbacks
Tennessee Volunteers
10/11/25 4:15PM
ARK
TENN
|
–
–
|
+350
-465
|
+12.5 (-110)
-12.5 (-110)
|
O 67.5 (-110)
U 67.5 (-110)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Indiana Hoosiers vs. Iowa Hawkeyes on September 27, 2025 at Kinnick Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
![]() |
LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
EMICH@CMICH | CMICH -148 | 62.8% | 7 | WIN |
SDGST@NOILL | SDGST -118 | 55.7% | 3 | WIN |
BAMA@GEORGIA | GEORGIA -125 | 58.7% | 7 | LOSS |
TENN@MISSST | MISSST +7.5 | 54.3% | 4 | WIN |
UK@SC | SC -5.5 | 54.8% | 4 | WIN |
WKY@MIZZST | MIZZST +4.5 | 55.6% | 6 | LOSS |
JAXST@USM | USM -3.5 | 56.0% | 5 | WIN |
NMEXST@NMEX | NMEX -14.5 | 56.9% | 6 | WIN |
ARIZ@IOWAST | ROCCO BECHT UNDER 1.5 PASS TDS | 55.5% | 5 | WIN |
TCU@ARIZST | JOSH HOOVER PASS YDS UNDER 287.5 | 53.4% | 3 | WIN |
ARIZST@BAYLOR | BAYLOR -130 | 58.4% | 6 | LOSS |
WYO@COLO | WYO +13.5 | 54.1% | 3 | LOSS |
TULANE@OLEMISS | MISS -11.5 | 54.3% | 4 | WIN |
UNC@UCF | UCF -6.5 | 54.4% | 4 | WIN |
ARKST@KENSAW | KENSAW +4.5 | 54.5% | 4 | WIN |
ILL@IND | IND -6 | 53.2% | 3 | WIN |
SELOU@LSU | LSU -47.5 | 55.3% | 5 | LOSS |
TNMART@MIZZST | MIZZST -14.5 | 56.2% | 6 | WIN |
FRESNO@HAWAII | HAWAII +3 | 56.6% | 6 | WIN |
MRSHL@MTSU | MTSU +2.5 | 56.8% | 6 | LOSS |
MICH@NEB | NEB +1.5 | 57.3% | 7 | LOSS |
WASH@WASHST | DENZEL BOSTON UNDER 69.5 RECV YDS | 56.2% | 6 | LOSS |
IOWA@RUT | ANTWAN RAYMOND OVER 0.5 TOUCHDOWNS | 54.4% | 4 | WIN |
GEORGIA@TENN | UNDER 50.5 | 55.5% | 6 | LOSS |
ARK@OLEMISS | MISS -225 | 72.0% | 9 | WIN |
DUKE@TULANE | TULANE -120 | 56.5% | 4 | WIN |
ARK@OLEMISS | MISS -6.5 | 53.9% | 3 | LOSS |
AKRON@UAB | UAB -11 | 54.7% | 4 | LOSS |
UCONN@DEL | DEL +9.5 | 55.0% | 5 | WIN |
APLST@USM | USM +4 | 55.3% | 6 | WIN |
MERIMK@KENSAW | KENSAW -13.5 | 56.2% | 7 | WIN |
UMASS@IOWA | IOWA -34.5 | 56.4% | 7 | WIN |
UMASS@IOWA | JAZIUN PATTERSON UNDER 0.5 RUSH TDS | 54.8% | 4 | WIN |
NMEX@UCLA | NICO IAMALEAVA UNDER 31.5 PASS ATT | 53.4% | 3 | LOSS |
KSTATE@ARIZ | ARIZ +1.5 | 56.1% | 6 | WIN |
BC@MICHST | NICK MARSH OVER 47.5 RCV YDS | 53.6% | 3 | WIN |
ARIZST@MISSST | MISSST +7 | 54.2% | 4 | WIN |
TULSA@NMEXST | NMEXST +3.5 | 56.9% | 6 | WIN |
UCLA@UNLV | OVER 54.5 | 56.2% | 6 | LOSS |
FRESNO@OREGST | FRESNO +1.5 | 54.7% | 4 | WIN |
VANDY@VATECH | VANDY +2.5 | 55.8% | 5 | WIN |
JMAD@LVILLE | LVILLE -14.5 | 54.0% | 3 | LOSS |
TCU@UNC | JOSEPH MANJACK OVER 37.5 RECV YDS | 53.8% | 3 | LOSS |
ND@MIAMI | MIAMI +3 | 55.2% | 6 | WIN |
MISSST@USM | USM +14.5 | 56.0% | 6 | LOSS |
UTAH@UCLA | UCLA +5.5 | 56.2% | 6 | LOSS |
CAL@OREGST | OREGST +1.5 | 55.1% | 5 | LOSS |
FAU@MD | MD -13.5 | 55.2% | 5 | WIN |
GAS@FRESNO | FRESNO +2 | 55.2% | 5 | WIN |
TOLEDO@UK | UK -9.5 | 56.2% | 6 | LOSS |
AUSTPEAY@MTSU | PEAY +12.5 | 56.2% | 6 | WIN |