BYU vs Colorado Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 27)

Updated: 2025-09-20T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The BYU Cougars and the Colorado Buffaloes square off on September 27, 2025, in what promises to be a hard-hitting non-conference matchup between two programs looking to make their mark nationally. BYU will lean on its disciplined, physical style, while Colorado hopes its high-paced offense and improving defense can shine in front of a raucous home crowd.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 27, 2025

Start Time: 10:15 PM EST​

Venue: Folsom Field​

Buffaloes Record: (2-2)

Cougars Record: (3-0)

OPENING ODDS

BYU Moneyline: -251

COLO Moneyline: +202

BYU Spread: -6.5

COLO Spread: +6.5

Over/Under: 47.5

BYU
Betting Trends

  • BYU has been inconsistent ATS on the road, often covering when their defense forces turnovers but struggling in high-scoring shootouts.

COLO
Betting Trends

  • Colorado has shown strength ATS at home, regularly thriving when their passing game ignites early and their defense holds opponents under 30 points.

MATCHUP TRENDS

  • Matchups between BYU and Pac-12 opponents have historically trended close, while Colorado has hit the over in a majority of home games where their offense dictates tempo, suggesting bettors could see another high-scoring contest here.

BYU vs. COLO
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: C. Roberts over 52.5 Receiving Yards.

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BYU vs Colorado Prediction & Odds:
Free CFB Betting Insights for 9/27/25

The September 27, 2025 clash between the BYU Cougars and the Colorado Buffaloes is shaping up to be one of the more compelling non-conference matchups of the season, a game that not only pits two teams with contrasting styles but also carries significant weight for both programs looking to bolster their national reputations and postseason résumés, and with the setting in Boulder’s Folsom Field, the energy is sure to match the stakes. BYU comes into this matchup leaning on its identity as a disciplined, physical football team that prides itself on winning in the trenches, controlling time of possession, and forcing opponents to play a slower, grind-it-out style that often frustrates more explosive teams. Their offensive line, consistently one of the more reliable units in college football, will be tasked with keeping their quarterback upright against a Colorado defense that has shown signs of improvement in applying pressure and creating disruption, while their running backs will look to chip away at the Buffaloes’ front seven in order to create balance and set up play-action opportunities. The Cougars’ passing game, although not as flashy as some, has been efficient and opportunistic, with receivers who can exploit soft spots in coverage and a quarterback who protects the football, making their offense difficult to derail once it finds rhythm. On the defensive side, BYU thrives on gap discipline and physicality, particularly in stopping the run, but they’ll be tested against a Colorado offense that thrives on tempo, speed, and explosive plays in the passing game.

The Buffaloes, under the bright lights and with a passionate home crowd behind them, will likely look to push the pace and force BYU into uncomfortable situations, spreading the field with multiple receivers and testing the Cougars’ secondary down the field, while also mixing in a ground attack that has shown the ability to break off big gains when defenses overcommit. Colorado’s quarterback, who has emerged as a leader and playmaker, will be a critical factor in this game, as his ability to avoid mistakes against BYU’s opportunistic defense could dictate whether the Buffaloes can sustain drives or stall under pressure. Their defense, while still working toward consistency, has developed playmakers at all three levels, and the ability of their secondary to contain BYU’s receivers without giving up chunk plays will be critical to preventing the Cougars from controlling the flow of the game. Special teams could also play a pivotal role, as BYU’s discipline often gives them an edge in field position while Colorado’s return units are always capable of swinging momentum with one big play in front of a home crowd desperate for a signature moment. Ultimately, this game may come down to whether BYU can impose its methodical, physical style on the road or if Colorado’s speed, explosiveness, and home-field energy can overwhelm the Cougars, and with both teams carrying plenty of motivation and needing a statement win at this stage in the season, fans should expect a dramatic contest that tests execution, discipline, and resilience in what could be one of the more underrated matchups of the week.

BYU Cougars CFB Preview

The BYU Cougars head into their September 27, 2025 matchup against Colorado with a clear identity that has carried them through recent seasons: disciplined, physical football anchored by line play and execution on both sides of the ball, and they know they’ll need to lean on those strengths if they want to leave Boulder with a statement win. Offensively, BYU relies on balance, with a strong ground game powered by a deep rotation of running backs and an offensive line that has consistently been among the program’s biggest assets, opening running lanes and keeping their quarterback protected against pressure-heavy defenses. The passing attack, while not designed to overwhelm with sheer volume, has been efficient and opportunistic, built on accurate throws, timing routes, and receivers who excel in exploiting coverage gaps, and it works best when set up by play-action after the run has been established. On the road, the Cougars know their ability to control time of possession is critical, because forcing Colorado’s high-paced offense to sit on the sideline will not only limit scoring opportunities but also neutralize the energy of the home crowd.

Defensively, BYU plays with gap discipline and physicality, focusing on eliminating the run first while relying on experienced linebackers to flow sideline to sideline and a secondary that has proven capable of preventing the kind of explosive plays Colorado thrives on when given space. That said, the challenge of defending an up-tempo Buffaloes attack will push the Cougars to stay fresh and avoid mental lapses, as even a single missed assignment could turn into a momentum-shifting play. BYU’s special teams are another steadying force, often helping them win field position battles and avoid the types of mistakes that can swing games on the road, while their kicker has proven reliable in pressure situations, which could be crucial in what projects to be a close contest. The Cougars are no strangers to tough road environments, having played a wide range of Power Five opponents in recent years, and that experience will be invaluable in adjusting to the atmosphere of Folsom Field, where crowd noise and altitude can rattle less disciplined teams. For BYU, this matchup is about proving they can take their brand of football—a blend of physicality, patience, and efficiency—into a hostile environment and execute under pressure, and if they succeed in dictating tempo, avoiding turnovers, and forcing Colorado to play their style rather than the other way around, they could walk away with not just a win but a defining moment in their season that solidifies their status as a program capable of beating anyone, anywhere.

The BYU Cougars and the Colorado Buffaloes square off on September 27, 2025, in what promises to be a hard-hitting non-conference matchup between two programs looking to make their mark nationally. BYU will lean on its disciplined, physical style, while Colorado hopes its high-paced offense and improving defense can shine in front of a raucous home crowd. BYU vs Colorado AI Prediction: Free CFB Betting Insights for Sep 27. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Colorado Buffaloes CFB Preview

The Colorado Buffaloes welcome BYU to Folsom Field on September 27, 2025, with the energy of a fan base that has rallied behind their resurgence and the expectation that their unique blend of tempo, explosiveness, and physicality can carry them to another statement victory at home, where they’ve proven to be especially tough to beat. Offensively, Colorado has found its rhythm behind a quarterback who has become the heartbeat of the team, combining composure in the pocket with playmaking ability when plays break down, and his rapport with a dynamic group of receivers has made the Buffaloes one of the more entertaining passing attacks in the nation. Their wideouts excel at creating separation and attacking downfield, putting constant stress on secondaries, while the running game complements this explosiveness with backs who can punish defenses if they overcommit to stopping the pass. Against BYU’s disciplined defense, Colorado’s ability to keep pace high and spread the field will be crucial, as they will look to tire out the Cougars’ front seven and create mismatches that allow them to seize momentum early. Defensively, the Buffaloes are still developing consistency, but they’ve improved under a system that emphasizes aggression and opportunism, with a front seven capable of disrupting the pocket and linebackers who are quick to close gaps in the running game.

Their secondary, while occasionally vulnerable to sharp route combinations, has enough talent and athleticism to make plays on the ball, and they’ll need to be sharp against BYU’s efficient passing attack, which thrives on punishing mistakes. Special teams could also play a pivotal role, as Colorado has a history of generating sparks through its return game, and in a matchup where momentum swings could define the outcome, one big play in that phase could ignite the crowd and shift the game’s tone. The atmosphere in Boulder will be electric, with the altitude and noise combining to create a challenging environment for any visiting team, and the Buffaloes know how to use that edge to their advantage, particularly against an opponent that thrives on precision and rhythm. For Colorado, this contest isn’t just about beating a disciplined BYU team; it’s about reinforcing their trajectory as a program on the rise, capable of defending their home turf against quality competition, and proving that their offensive firepower and improved defensive toughness can win consistently at the national level. A victory would provide a major boost to their postseason ambitions and further validate the progress being made under their current leadership, setting the tone for the remainder of their schedule and keeping the Buffaloes squarely in the national conversation.

BYU vs. Colorado Prop Picks (AI)

Remi is pouring through mountains of stats on each team. In fact, anytime the Cougars and Buffaloes play there’s always several intriguing angles to key in on. Not to mention games played at Folsom Field in Sep rarely follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: C. Roberts over 52.5 Receiving Yards.

BYU vs. Colorado Prediction (AI)

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Remi, our AI sports algorithm, has been pouring over exorbitant amounts of data from every past game between the Cougars and Buffaloes and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.

The Algorithm has been most fixated on the unproportionally assigned weight knucklehead sportsbettors regularly put on BYU’s strength factors between a Cougars team going up against a possibly strong Buffaloes team. We’ve found the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI BYU vs Colorado picks, computer picks Cougars vs Buffaloes, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Cougars Betting Trends

BYU has been inconsistent ATS on the road, often covering when their defense forces turnovers but struggling in high-scoring shootouts.

Buffaloes Betting Trends

Colorado has shown strength ATS at home, regularly thriving when their passing game ignites early and their defense holds opponents under 30 points.

Cougars vs. Buffaloes Matchup Trends

Matchups between BYU and Pac-12 opponents have historically trended close, while Colorado has hit the over in a majority of home games where their offense dictates tempo, suggesting bettors could see another high-scoring contest here.

BYU vs. Colorado Game Info

BYU vs Colorado starts on September 27, 2025 at 10:15 PM EST.

Spread: Colorado +6.5
Moneyline: BYU -251, Colorado +202
Over/Under: 47.5

BYU: (3-0)  |  Colorado: (2-2)

Remi's searched hard and found the best prop for this matchup: C. Roberts over 52.5 Receiving Yards.. Prices move—always shop for the best number.

Matchups between BYU and Pac-12 opponents have historically trended close, while Colorado has hit the over in a majority of home games where their offense dictates tempo, suggesting bettors could see another high-scoring contest here.

BYU trend: BYU has been inconsistent ATS on the road, often covering when their defense forces turnovers but struggling in high-scoring shootouts.

COLO trend: Colorado has shown strength ATS at home, regularly thriving when their passing game ignites early and their defense holds opponents under 30 points.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

BYU vs. Colorado Odds

AI algorithm Remi is pouring through tons of data points on each player. In fact, anytime the BYU vs Colorado trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme temps rarely follow normal, predictable betting trends.

BYU vs Colorado Opening Odds

BYU Moneyline: -251
COLO Moneyline: +202
BYU Spread: -6.5
COLO Spread: +6.5
Over/Under: 47.5

BYU vs Colorado Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-360
 
-9.5 (-105)
O 55 (-118)
U 55 (-107)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-115
-105
-1 (-110)
+1 (-110)
O 51 (-110)
U 51 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-240
+185
-6.5 (-112)
+6.5 (-109)
O 56 (-110)
U 56 (-112)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4500
+1550
-26.5 (-110)
+26.5 (-110)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+160
-205
+4.5 (-110)
-4.5 (-110)
O 50 (-112)
U 50 (-110)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1700
+950
-21.5 (-110)
+21.5 (-110)
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-400
+310
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-305
+240
-7.5 (-105)
+7.5 (-115)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+115
-2.5 (-110)
+2.5 (-110)
O 58.5 (-110)
U 58.5 (-110)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-210
+175
-5 (-110)
+5 (-110)
O 63.5 (-110)
U 63.5 (-110)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1200
-5000
+25.5 (-113)
-25.5 (-108)
O 54.5 (-115)
U 54.5 (-106)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+228
-285
+7 (-110)
-7 (-110)
O 43 (-110)
U 43 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-480
+360
-12.5 (-110)
+12.5 (-110)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-175
+148
-3.5 (-110)
+3.5 (-110)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+600
-1000
+17.5 (-112)
-17.5 (-109)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-600
 
-14.5 (-110)
O 63 (-110)
U 63 (-110)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+180
-220
+5 (-110)
-5 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-155
+3 (-110)
-3 (-110)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
+100
-120
+1 (-110)
-1 (-110)
O 57 (-110)
U 57 (-110)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+285
-365
+9.5 (-110)
-9.5 (-110)
O 48 (-115)
U 48 (-105)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-420
+320
-10.5 (-115)
+10.5 (-105)
O 49 (-110)
U 49 (-110)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-110)
-3 (-110)
O 61.5 (-110)
U 61.5 (-110)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+270
-345
+8.5 (-110)
-8.5 (-110)
O 39 (-110)
U 39 (-110)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-480
+360
-12 (-110)
+12 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+120
-152
+2.5 (-105)
-2.5 (-117)
O 48.5 (-115)
U 48.5 (-106)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-225
+185
-6 (-110)
+6 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+175
-210
+5.5 (-110)
-5.5 (-110)
O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-105
-115
+1 (-110)
-1 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+475
-750
+15.5 (-110)
-15.5 (-110)
O 62.5 (-113)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+162
-195
+4.5 (-110)
-4.5 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-800
 
-16.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-155
+130
-3 (-110)
+3 (-110)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+118
-140
+2.5 (-110)
-2.5 (-110)
O 52.5 (-105)
U 52.5 (-115)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+200
-260
+6.5 (-107)
-6.5 (-114)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+105
 
+1.5 (-110)
 
O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+335
 
+11 (-110)
 
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+2800
-10000
+38.5 (-114)
-38.5 (-107)
O 56.5 (-110)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+162
-195
+4.5 (-110)
-4.5 (-110)
O 67.5 (-110)
U 67.5 (-110)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-267
+215
-7 (-105)
+7 (-115)
O 44.5 (-115)
U 44.5 (-105)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-750
+450
-15.5 (-110)
+15.5 (-110)
O 55.5 (-107)
U 55.5 (-114)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-110)
-33.5 (-110)
O 44.5 (-110)
U 44.5 (-110)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+270
-345
+9.5 (-110)
-9.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30 (-109)
-30 (-112)
O 45.5 (-112)
U 45.5 (-109)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 62.5 (-110)
U 62.5 (-110)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-650
+460
-14.5 (-115)
+14.5 (-105)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-145
+122
-2.5 (-115)
+2.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1350
-3500
+25.5 (-110)
-25.5 (-110)
O 55 (-110)
U 55 (-110)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+185
-225
+5.5 (-110)
-5.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-360
+275
-9.5 (-107)
+9.5 (-114)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+235
-310
+7.5 (-115)
-7.5 (-107)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+400
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers BYU Cougars vs. Colorado Buffaloes on September 27, 2025 at Folsom Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN