TCU vs Arizona State Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 26)
Updated: 2025-09-19T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
TCU (3–0) travels to Tempe to face Arizona State (3–1) on September 26, 2025 in what shapes up as a marquee early Big 12 battle with major conference implications. Oddsmakers opened the game with ASU favored by around 3 points, and the over/under is set near 54.5, suggesting expectations for a fast-paced, high-scoring contest.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Sep 26, 2025
Start Time: 9:00 PM EST
Venue: Mountain America Stadium
Sun Devils Record: (3-1)
Horned Frogs Record: (3-0)
OPENING ODDS
TCU Moneyline: +111
ARIZST Moneyline: -133
TCU Spread: +2.5
ARIZST Spread: -2.5
Over/Under: 55.5
TCU
Betting Trends
- TCU has covered in 2 of its first 3 games (2–1 ATS) this season.
ARIZST
Betting Trends
- Arizona State is 2–2 ATS in 2025, having covered two of its four games thus far.
MATCHUP TRENDS
- Sharp money has reportedly moved the line slightly toward TCU after early betting, indicating confidence in the Frogs’ balanced offense and resilience on the road. Also, total movement toward the under has gained traction following strong defensive performances from both sides in recent weeks.
TCU vs. ARIZST
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: J. Dwyer over 62.5 Receiving Yards.
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TCU vs Arizona State Prediction & Odds:
Free CFB Betting Insights for 9/26/25
The September 26, 2025 showdown between TCU and Arizona State in Tempe is one of the more intriguing Big 12 matchups of the week, featuring a Horned Frogs team that has started 3–0 and climbed into the Top 25 against a Sun Devils squad that sits at 3–1 and has shown both balance and explosiveness on offense. TCU’s profile so far this season has been that of a team built on versatility: they can lean on their running game to control tempo and wear down defenses, but they also have a quarterback and receiving corps capable of stretching the field vertically and punishing teams that stack the box. Their defense, while not perfect, has held up well in pressure situations and has shown the ability to adjust to different offensive schemes, something they will need against Arizona State’s uptempo system. The Sun Devils have been highly efficient in 2025, averaging nearly 30 points per game while posting impressive rushing numbers at over 5.3 yards per carry and protecting the football with balance through the air. Quarterback play has been steady, their offensive line has provided strong protection, and the unit has excelled in the red zone, converting nearly 90 percent of its opportunities into points, a critical metric in a game expected to be tight.
Arizona State’s defense has been opportunistic but will be tested heavily by TCU’s speed and playmaking ability, particularly if the Horned Frogs find ways to sustain long drives that keep the Sun Devils’ offense off the field. For TCU, the key is to limit mistakes, win in the trenches, and force Arizona State into obvious passing downs where their pass rush can create pressure. For Arizona State, the mission is to set the tempo early, utilize their balanced offense to stretch TCU’s defense, and use the home-field advantage and desert heat to wear down the Horned Frogs over four quarters. Oddsmakers opened this contest with ASU as a narrow 3-point favorite, reflecting just how evenly matched these teams appear on paper, and with early betting action slightly tilting toward TCU, it underscores the perception that the Frogs’ undefeated start is no fluke. Ultimately, this matchup is likely to be decided by situational football—third-down conversions, red-zone efficiency, and turnover margin. If TCU’s defense can limit big plays and force Arizona State to work methodically down the field, they’ll be in a strong position to grind out a road win. But if the Sun Devils can impose their pace, protect their quarterback, and finish drives, they have the tools to defend home turf in what should be one of the most closely contested conference games of the week.
Get live CFB odds and precise AI CFB picks, predictions, and cover probabilities.
🥇 𝗗𝗮𝘃𝗲𝘆 𝗢’𝗕𝗿𝗶𝗲𝗻 𝗚𝗿𝗲𝗮𝘁 𝟴 𝗵𝗼𝗻𝗼𝗿𝘀#GoFrogs 🐸 @JoshJHoover pic.twitter.com/pVmxdRCKuN
— TCU Football (@TCUFootball) September 23, 2025
TCU Horned Frogs CFB Preview
The TCU Horned Frogs head into Tempe for their September 26, 2025 matchup against Arizona State with momentum and confidence, sitting at 3–0 and carrying the kind of balance that makes them dangerous in conference play. Their offense has proven it can adapt to multiple game scripts, leaning on a physical rushing attack to control tempo when needed but also stretching defenses vertically with a quarterback who has shown poise and receivers capable of winning one-on-one battles downfield. Against the Sun Devils, TCU will look to establish the run early, forcing Arizona State’s defense to commit resources to the box, which can then open up opportunities in the passing game through play-action and deep shots. Their offensive line has been solid through three weeks, but they must maintain that standard in what will be their toughest environment yet, as the Sun Devils’ front seven has been disruptive and opportunistic. Defensively, the Frogs know the challenge will be containing Arizona State’s balanced offense, which has been efficient both on the ground and through the air and has thrived in the red zone.
TCU’s front must win at the line of scrimmage, maintain gap integrity to prevent chunk runs, and generate consistent pressure on passing downs without leaving themselves vulnerable to big plays over the top. Their secondary will need to remain disciplined against an offense that can use tempo and misdirection to create mismatches, while linebackers must be sharp in coverage against running backs and tight ends. On special teams, TCU cannot afford mistakes in field position, as hidden yardage could swing the outcome in a game where oddsmakers project a tight margin. From a betting perspective, the Horned Frogs’ 2–1 ATS record this season reflects their reliability, and early sharp money has leaned toward them as a live underdog with the tools to travel well. To secure a statement road win, TCU must stay balanced offensively, capitalize on turnovers, and avoid letting Arizona State dictate tempo with quick strikes. If they can execute cleanly, withstand the heat and crowd noise, and maintain poise in late-game situations, the Horned Frogs have every chance to leave Tempe with an undefeated record intact and a rising profile in the Big 12 race.
Credit: USA TODAY/IMAGN
Arizona State Sun Devils CFB Preview
The Arizona State Sun Devils return to Tempe on September 26, 2025 carrying a 3–1 record and a reputation for offensive efficiency that has made them one of the more dangerous teams in the Big 12 early in the season. Their offense has thrived on balance, with a rushing attack averaging over 5.3 yards per carry and a passing game that has delivered timely strikes behind an offensive line that has done a strong job of keeping the pocket clean. Quarterback play has been steady and efficient, spreading the ball to multiple targets while avoiding costly turnovers, and the Sun Devils have been excellent in the red zone, scoring on nearly 90 percent of their trips, which gives them confidence in finishing drives against quality competition. Against TCU, Arizona State will look to use tempo and play-action to stress the Frogs’ defense, forcing linebackers into difficult assignments and creating mismatches for receivers downfield.
Their offensive line will be tested by TCU’s aggressive front, but the Sun Devils have shown the ability to adjust with quick throws and a versatile run game that can keep defenses guessing. Defensively, Arizona State has shown flashes of disruption, generating tackles for loss and turnovers in key moments, but their biggest challenge will be slowing down a TCU offense that thrives on balance and can grind out long drives. The Sun Devils’ front seven must hold their ground against the run and collapse the pocket without leaving vulnerabilities on the edges, while the secondary must be disciplined against TCU’s vertical passing threats. Special teams could provide a hidden advantage, as field position and clean execution will be vital in a game projected to be decided by one score. From a betting perspective, Arizona State’s 2–2 ATS record shows inconsistency, but their home-field advantage and offensive firepower make them a slight favorite, and the desert environment could give them an additional edge as the game wears on. For the Sun Devils to defend their turf, they must sustain their offensive rhythm, avoid self-inflicted mistakes, and capitalize on their opportunities in the red zone. If they execute those elements, Arizona State has every chance to hold off an unbeaten TCU squad and solidify themselves as a legitimate contender in the Big 12.
Wallpaper Wednesday, blackout edition. pic.twitter.com/JP7BmXsJeB
— Sun Devil Football (@ASUFootball) September 24, 2025
TCU vs Arizona State Prop Picks (AI)
AI algorithm Remi is pouring through mountains of data on each player. In fact, anytime the Horned Frogs and Sun Devils play there’s always several intriguing observations to key in on. Not to mention games played at Mountain America Stadium in Sep can often follow normal, predictable betting trends.
TCU vs Arizona State Prediction (AI)
Remi, our AI sports genius, has been pouring over millions of data from every facet between the Horned Frogs and Sun Devils and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.
The Algorithm has been most focused on the growing weight human bettors regularly put on player performance factors between a Horned Frogs team going up against a possibly unhealthy Sun Devils team. It appears the true game analytics appear to reflect a strong lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.
Below is our current AI TCU vs Arizona State picks, computer picks Horned Frogs vs Sun Devils, best bets, model edges, confidence ratings.
| DATE | GAME | LEAN | %WIN | UNITS | LEVEL | |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule.
TCU Betting Trends
TCU has covered in 2 of its first 3 games (2–1 ATS) this season.
Arizona State Betting Trends
Arizona State is 2–2 ATS in 2025, having covered two of its four games thus far.
Horned Frogs vs. Sun Devils Matchup Trends
Sharp money has reportedly moved the line slightly toward TCU after early betting, indicating confidence in the Frogs’ balanced offense and resilience on the road. Also, total movement toward the under has gained traction following strong defensive performances from both sides in recent weeks.
TCU vs. Arizona State Game Info
TCU vs Arizona State starts on September 26, 2025 at 9:00 PM EST.
Venue: Mountain America Stadium.
Spread: Arizona State -2.5
Moneyline: TCU +111, Arizona State -133
Over/Under: 55.5
TCU: (3-0) | Arizona State: (3-1)
Remi's searched hard and found the best prop for this matchup: J. Dwyer over 62.5 Receiving Yards.. Prices move—always shop for the best number.
Sharp money has reportedly moved the line slightly toward TCU after early betting, indicating confidence in the Frogs’ balanced offense and resilience on the road. Also, total movement toward the under has gained traction following strong defensive performances from both sides in recent weeks.
TCU trend: TCU has covered in 2 of its first 3 games (2–1 ATS) this season.
ARIZST trend: Arizona State is 2–2 ATS in 2025, having covered two of its four games thus far.
See our latest CFB picks and odds pages for 2025 to compare prices before you bet.
TCU vs. Arizona State Odds
Remi is pouring through loads of stats on each team. In fact, anytime the TCU vs Arizona State trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable patterns.
| TCU Moneyline | +111 |
|---|---|
| ARIZST Moneyline | -133 |
| TCU Spread | +2.5 |
| ARIZST Spread | -2.5 |
| Over / Under | 55.5 |
TCU vs Arizona State Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Dec 5, 2025 7:00PM EST
Troy Trojans
James Madison Dukes
12/5/25 7PM
TROY
JMAD
|
–
–
|
+1000
-2500
|
+23.5 (-110)
-23.5 (-110)
|
O 46.5 (-110)
U 46.5 (-110)
|
|
|
Dec 5, 2025 7:00PM EST
Kennesaw State Owls
Jacksonville State Gamecocks
12/5/25 7PM
KENSAW
JAXST
|
–
–
|
-135
+115
|
-2.5 (-110)
+2.5 (-110)
|
O 60.5 (-110)
U 60.5 (-110)
|
|
|
Dec 5, 2025 8:00PM EST
North Texas Mean Green
Tulane Green Wave
12/5/25 8PM
NOTEX
TULANE
|
–
–
|
-135
+115
|
-2.5 (-110)
+2.5 (-110)
|
O 66.5 (-105)
U 66.5 (-115)
|
|
|
Dec 5, 2025 8:01PM EST
UNLV Rebels
Boise State Broncos
12/5/25 8:01PM
UNLV
BOISE
|
–
–
|
+180
-220
|
+5 (-110)
-5 (-110)
|
O 59 (-110)
U 59 (-110)
|
|
|
Dec 6, 2025 12:00PM EST
Miami Ohio Redhawks
Western Michigan Broncos
12/6/25 12PM
MIAOH
WMICH
|
–
–
|
-125
|
-1.5 (-110)
|
O 43.5 (-105)
U 43.5 (-115)
|
|
|
Dec 6, 2025 12:00PM EST
BYU Cougars
Texas Tech Red Raiders
12/6/25 12PM
BYU
TXTECH
|
–
–
|
+390
-550
|
+12.5 (-110)
-12.5 (-110)
|
O 49.5 (-110)
U 49.5 (-110)
|
|
|
Dec 6, 2025 4:00PM EST
Georgia Bulldogs
Alabama Crimson Tide
12/6/25 4PM
UGA
BAMA
|
–
–
|
-135
+115
|
-2.5 (-110)
+2.5 (-110)
|
O 48 (-110)
U 48 (-110)
|
|
|
Dec 6, 2025 8:00PM EST
Duke Blue Devils
Virginia Cavaliers
12/6/25 8PM
DUKE
UVA
|
–
–
|
+155
-180
|
+4 (-110)
-4 (-110)
|
O 58 (-110)
U 58 (-110)
|
|
|
Dec 6, 2025 8:01PM EST
Indiana Hoosiers
Ohio State Buckeyes
12/6/25 8:01PM
IND
OHIOST
|
–
–
|
+160
-185
|
+4 (-110)
-4 (-110)
|
O 47.5 (-115)
U 47.5 (-105)
|
|
|
Dec 13, 2025 3:00PM EST
Army Black Knights
Navy Midshipmen
12/13/25 3PM
ARMY
NAVY
|
–
–
|
+165
-195
|
+4.5 (-110)
-4.5 (-110)
|
O 38 (-110)
U 38 (-110)
|
CFB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers TCU Horned Frogs vs. Arizona State Sun Devils on September 26, 2025 at Mountain America Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.
| LEAN | %WIN | UNITS | RESULT | |
|---|---|---|---|---|
| COLO@KSTATE | COLO +17.5 | 54.0% | 4 | WIN |
| PSU@RUT | RUT +14 | 52.8% | 1 | WIN |
| OHIOST@MICH | MICH +10.5 | 56.4% | 6 | LOSS |
| VATECH@UVA | VATECH +8 | 57.8% | 7 | LOSS |
| NWEST@ILL | LUKE ALTMYER UNDER 19.5 PASS COMP | 54.3% | 4 | WIN |
| ORE@WAS | DEMOND WILLIAMS JR UNDER 43.5 RUSH YDS | 55.2% | 5 | WIN |
| MIAMI@VATECH | VATECH +18.5 | 54.2% | 4 | WIN |
| GAST@TROY | TROY -9.5 | 55.7% | 5 | WIN |
| DEL@WAKE | DEL +18 | 56.7% | 6 | LOSS |
| NMEX@AF | NMEX -3.5 | 56.1% | 5 | WIN |
| WASHST@JMAD | WASHST +14.5 | 55.3% | 5 | WIN |
| ILL@WISC | WISC +9 | 55.1% | 5 | WIN |
| WKY@LSU | WKY +23.5 | 56.3% | 6 | WIN |
| WASH@UCLA | DEMOND WILLIAMS UNDER 27.5 PASS ATT | 56.3% | 6 | WIN |
| TCU@HOU | AMARE THOMAS OVER 69.5 RECV YDS | 55.2% | 5 | WIN |
| TEX@UGA | NATE FRAZIER UNDER 65.5 RUSH + REC YDS | 55.5% | 5 | WIN |
| PUR@WASH | ANTONIO HARRIS UNDER 73.5 RUSH + REC YDS | 54.1% | 4 | WIN |
| OKLA@BAMA | UNDER 46 | 52.4% | 2 | WIN |
| UVA@DUKE | DUKE -3.5 | 54.7% | 3 | LOSS |
| OKLA@BAMA | BAMA -6 | 54.5% | 3 | LOSS |
| OREGST@TULSA | OREGST -120 | 55.6% | 5 | LOSS |
| UTEP@MIZZST | MIZZST -5 | 54.3% | 4 | WIN |
| COLOST@NMEX | NMEX -14 | 57.1% | 6 | LOSS |
| PSU@MICHST | MICHST +7.5 | 56.5% | 6 | LOSS |
| MISSST@MIZZOU | MISSST +7.5 | 57.2% | 7 | LOSS |
| FAU@TULANE | FAU +17.5 | 56.0% | 6 | WIN |
| NCST@MIAMI | NCST +15.5 | 57.1% | 7 | LOSS |
| KENTST@AKRON | AKRON -6.5 | 55.4% | 5 | LOSS |
| JAXST@UTEP | JAXST -105 | 57.0% | 7 | WIN |
| FSU@CLEM | CLEM -118 | 57.1% | 5 | WIN |
| UNLV@COLOST | UNLV -4 | 55.2% | 5 | WIN |
| OREG@IOWA | IOWA +6.5 | 53.3% | 2 | WIN |
| NEB@UCLA | NEB +1.5 | 55.8% | 5 | WIN |
| KENSAW@NMEXST | NMEXST +10 | 56.5% | 6 | WIN |
| STNFRD@UNC | STNFRD +7.5 | 53.8% | 3 | WIN |
| DUKE@UCONN | UCONN +8.5 | 57.9% | 7 | WIN |
| NEVADA@UTAHST | NEVADA +9.5 | 55.9% | 5 | LOSS |
| SAMST@OREGST | SAMST +21 | 57.7% | 7 | WIN |
| NEB@UCLA | NICO IAMALEAVA UNDER 180.5 PASS YDS | 56.6% | 6 | LOSS |
| HOU@UCF | HOU -112 | 58.0% | 6 | WIN |
| GASTHRN@APPST | GASTHRN +180 | 36.5% | 2 | WIN |
| KENTST@BALLST | BALLST -2.5 | 54.5% | 4 | WIN |
| WAKE@FSU | WAKE +10.5 | 56.4% | 6 | LOSS |
| WYO@SDGST | SDGST -10.5 | 56.7% | 7 | WIN |
| OKLA@TENN | TENN -130 | 58.3% | 5 | LOSS |
| GATECH@NCST | GATECH -5 | 56.4% | 6 | LOSS |
| MIAMI@SMU | MIAMI -10 | 54.3% | 4 | LOSS |
| IND@MD | MD +21.5 | 54.6% | 4 | LOSS |
| CINCY@UTAH | CINCY +11 | 57.6% | 7 | LOSS |
| OLDDOM@LAMON | LAMON +17 | 58.4% | 8 | LOSS |
| VANDY@TEXAS | OVER 46.5 | 53.7% | 2 | WIN |