Northern Illinois vs Mississippi State Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 20)

Updated: 2025-09-13T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

Mississippi State comes in 2-0, having narrowly upset No. 12 Arizona State and opening strong at home, while Northern Illinois enters at 1-1 after splitting its first two games and now faces a Power Five road test. The Bulldogs are expected to be solid favorites, with bettors anticipating they’ll need to be wary of Northern Illinois’ history of pulling off surprises and playing physical on both sides of the ball.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 20, 2025

Start Time: 4:15 PM EST​

Venue: Davis Wade Stadium at Scott Field​

Bulldogs Record: (3-0)

Huskies Record: (1-1)

OPENING ODDS

NILL Moneyline: +1078

MISSST Moneyline: -2174

NILL Spread: +21.5

MISSST Spread: -21.5

Over/Under: 49.5

NILL
Betting Trends

  • Northern Illinois is 1-1 ATS so far in 2025; in road games they’ve shown some ability to keep it close, notably in their opener vs. Maryland and in other games where they weren’t heavily favored. Their road vs. spread record indicates that while wins are harder to come by, they tend to outperform expectations when matched up as underdogs.

MISSST
Betting Trends

  • Mississippi State is also 2-0 ATS to start the season. Their wins over Southern Miss and Arizona State both came with them being favored by meaningful spreads, and they have covered those lines. Their offense has done enough and the defense has made key plays in presumably tight moments, giving confidence to those backing them at home.

MATCHUP TRENDS

  • The betting market is showing that Mississippi State is favored by a comfortable margin, but not overwhelmingly — the spread leaves room for Northern Illinois to cover, especially if there are turnovers or MSU is sloppy. The Over/Under is expected to be moderate-high, reflecting expectations that MSU will score and NIU could find some offensive moments. Northern Illinois’ ability to upset in Power Five matchups in past seasons gives underdog value appeal, while Mississippi State’s trend of covering early gives confidence to home‐backers. Also notable is that Northern Illinois has seen totals go under in its recent games, which might make the Over attractive for this matchup if bettors believe Mississippi State will push a fast pace.

NILL vs. MISSST
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: C. Wright over 46.5 Rushing Yards.

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Northern Illinois vs Mississippi State Prediction & Odds:
Free CFB Betting Insights for 9/20/25

The September 20, 2025, matchup between the Northern Illinois Huskies and the Mississippi State Bulldogs in Starkville sets up as a classic early-season clash between a Group of Five program with a history of punching above its weight and an SEC team looking to maintain momentum and prove itself against an opponent it is expected to handle. Mississippi State enters undefeated at 2-0, including an impressive win over No. 12 Arizona State that showcased their ability to compete against ranked opposition, while Northern Illinois sits at 1-1 and is trying to build on the foundation of toughness and resiliency that has defined the program for years. For Mississippi State, the keys are straightforward: establish dominance in the trenches, use their superior athleticism to create mismatches, and avoid the complacency that can sometimes creep in during nonconference games against smaller programs. Their offense has shown balance through the first two weeks, with the quarterback effectively spreading the ball to multiple receivers and the running game providing consistency, while the defense has generated timely stops and turnovers that allowed them to outlast Arizona State in a close game. Northern Illinois will be tasked with matching Mississippi State’s physicality at the line of scrimmage, leaning on a ground attack that can control tempo and a passing game that must make the most of limited opportunities.

The Huskies are no strangers to facing Power Five opponents on the road and have occasionally pulled off upsets by forcing turnovers, stealing momentum on special teams, and playing mistake-free football, but their margin for error is razor-thin against a Bulldogs team that thrives when it gets rolling early. The betting market reflects this dynamic, with Mississippi State favored by multiple scores, but Northern Illinois has a track record of outperforming expectations as an underdog, especially when their defense holds firm early and keeps the score manageable. The Over/Under points line suggests oddsmakers expect Mississippi State to control scoring, but NIU’s chances of covering hinge on their ability to sustain long drives and avoid three-and-outs that would give the Bulldogs too many possessions. Ultimately, this matchup should be about Mississippi State proving consistency and building depth, while Northern Illinois aims to show resilience and competitiveness. If Mississippi State starts fast, capitalizes on their home-field advantage, and plays with the same edge that earned them a win over a ranked opponent, they should cruise to victory and cover the spread. If they falter or overlook the Huskies, NIU has the grit and opportunism to hang around longer than expected, though an outright upset would require a near-perfect performance. This game is less about whether Mississippi State will win and more about whether Northern Illinois can make them sweat and whether the Bulldogs can show the dominance that SEC contenders are expected to display against smaller-conference foes.

Northern Illinois Huskies CFB Preview

The Northern Illinois Huskies enter their September 20, 2025, road matchup against Mississippi State as heavy underdogs, but they are no strangers to taking on Power Five opponents and will see this as another opportunity to prove their mettle on a big stage. At 1-1, the Huskies have already shown flashes of what makes them a dangerous underdog, combining a hard-nosed running game with a defense that can create problems when it plays disciplined, gap-sound football. Their offensive identity revolves around establishing the ground attack early, chewing up clock, and keeping games within striking distance by limiting possessions, and against Mississippi State, that formula will be critical if they want to prevent the Bulldogs from overwhelming them with superior speed and depth. The Huskies’ quarterback will be asked to make smart, timely throws, taking what the defense gives him and avoiding the costly turnovers that could turn a close game into a rout, while the offensive line must play its best game of the season to withstand the pressure from an SEC-caliber front seven.

On defense, Northern Illinois will look to keep everything in front of them, forcing Mississippi State to sustain long drives and hoping to create turnovers in the red zone, while their secondary will be tested against a passing game that has shown the ability to stretch the field. Special teams may also prove vital, as flipping field position and potentially generating a big return or block could provide the kind of momentum swing an underdog needs in a hostile environment. From a betting perspective, Northern Illinois has historically performed better against the spread as a road underdog than many expect, and their gritty style of play often lends itself to closer margins if they avoid early mistakes. Their path to success will hinge on starting fast, staying disciplined, and not allowing Mississippi State to build confidence or take control of the tempo, particularly in the first half. While an outright win would be a tall order given the disparity in talent and depth, the Huskies can absolutely play themselves into a competitive contest if they stick to their identity, control the clock, and capitalize on any Bulldogs miscues. For Northern Illinois, this is less about shocking the college football world and more about demonstrating their toughness, showing recruits and fans alike that they are capable of standing toe-to-toe with SEC opponents, and gaining confidence heading into the heart of their MAC schedule.

Mississippi State comes in 2-0, having narrowly upset No. 12 Arizona State and opening strong at home, while Northern Illinois enters at 1-1 after splitting its first two games and now faces a Power Five road test. The Bulldogs are expected to be solid favorites, with bettors anticipating they’ll need to be wary of Northern Illinois’ history of pulling off surprises and playing physical on both sides of the ball. Northern Illinois vs Mississippi State AI Prediction: Free CFB Betting Insights for Sep 20. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Mississippi State Bulldogs CFB Preview

The Mississippi State Bulldogs return to Davis Wade Stadium on September 20, 2025, with confidence and momentum as they prepare to host Northern Illinois in a nonconference clash that is expected to test their consistency more than their talent. Sitting at 2-0 after an impressive early-season win over Arizona State, the Bulldogs have already shown the kind of resilience and execution that head coach Jeff Lebby wants to define his program, and this matchup provides a prime opportunity to fine-tune before heading into the grind of SEC play. Offensively, Mississippi State has found balance behind a steady quarterback who has distributed the ball effectively, a rushing attack that has controlled tempo, and an offensive line that has both protected well and created lanes against quality competition. Against Northern Illinois, the Bulldogs’ offense will look to set the tone early, striking with quick scoring drives to prevent the Huskies from gaining confidence and attempting to control the pace of the game with their run-heavy approach. Defensively, Mississippi State has been opportunistic, forcing turnovers and tightening up in the red zone, and in this game they will be expected to overwhelm a Northern Illinois offensive line that lacks the depth and athleticism to consistently hold off SEC-caliber defenders.

Their defensive front should have opportunities to generate pressure, collapse the pocket, and force hurried throws, which could lead to mistakes that swing the game further in their favor. Special teams have been solid through two games, and in matchups like this, that consistency in field position and kicking execution can quietly extend the margin between the teams. From a betting perspective, Mississippi State has rewarded backers so far with a 2-0 ATS record, covering spreads even when expectations were high, and oddsmakers will again install them as significant favorites. To cover comfortably in this contest, the Bulldogs need to avoid complacency, stay sharp in execution, and not allow Northern Illinois to linger into the second half with long, clock-draining drives. The key will be translating their talent advantage into dominance on the field by maintaining focus in all three phases. Ultimately, Mississippi State has the depth, athleticism, and home-field advantage to handle this matchup decisively, and this game serves as an opportunity not only to improve to 3-0 but also to showcase that they can take care of business against teams they are expected to beat, something that strong SEC contenders must do consistently.

Northern Illinois vs. Mississippi State Prop Picks (AI)

AI algorithm Remi is pouring through loads of datapoints on each line. In fact, anytime the Huskies and Bulldogs play there’s always several intriguing observations to key in on. Not to mention games played at Davis Wade Stadium at Scott Field in Sep can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: C. Wright over 46.5 Rushing Yards.

Northern Illinois vs. Mississippi State Prediction (AI)

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Remi, our AI sports genius, has been pouring over tons of data from every angle between the Huskies and Bulldogs and using recursive machine learning and impressive AI to analyze the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most watching on the growing emphasis knucklehead sportsbettors regularly put on coaching factors between a Huskies team going up against a possibly healthy Bulldogs team. Trends look to say the true game analytics might reflect a slight lean against one Vegas line specifically.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI Northern Illinois vs Mississippi State picks, computer picks Huskies vs Bulldogs, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Huskies Betting Trends

Northern Illinois is 1-1 ATS so far in 2025; in road games they’ve shown some ability to keep it close, notably in their opener vs. Maryland and in other games where they weren’t heavily favored. Their road vs. spread record indicates that while wins are harder to come by, they tend to outperform expectations when matched up as underdogs.

Bulldogs Betting Trends

Mississippi State is also 2-0 ATS to start the season. Their wins over Southern Miss and Arizona State both came with them being favored by meaningful spreads, and they have covered those lines. Their offense has done enough and the defense has made key plays in presumably tight moments, giving confidence to those backing them at home.

Huskies vs. Bulldogs Matchup Trends

The betting market is showing that Mississippi State is favored by a comfortable margin, but not overwhelmingly — the spread leaves room for Northern Illinois to cover, especially if there are turnovers or MSU is sloppy. The Over/Under is expected to be moderate-high, reflecting expectations that MSU will score and NIU could find some offensive moments. Northern Illinois’ ability to upset in Power Five matchups in past seasons gives underdog value appeal, while Mississippi State’s trend of covering early gives confidence to home‐backers. Also notable is that Northern Illinois has seen totals go under in its recent games, which might make the Over attractive for this matchup if bettors believe Mississippi State will push a fast pace.

Northern Illinois vs. Mississippi State Game Info

Northern Illinois vs Mississippi State starts on September 20, 2025 at 4:15 PM EST.

Venue: Davis Wade Stadium at Scott Field.

Spread: Mississippi State -21.5
Moneyline: Northern Illinois +1078, Mississippi State -2174
Over/Under: 49.5

Northern Illinois: (1-1)  |  Mississippi State: (3-0)

Remi's searched hard and found the best prop for this matchup: C. Wright over 46.5 Rushing Yards.. Prices move—always shop for the best number.

The betting market is showing that Mississippi State is favored by a comfortable margin, but not overwhelmingly — the spread leaves room for Northern Illinois to cover, especially if there are turnovers or MSU is sloppy. The Over/Under is expected to be moderate-high, reflecting expectations that MSU will score and NIU could find some offensive moments. Northern Illinois’ ability to upset in Power Five matchups in past seasons gives underdog value appeal, while Mississippi State’s trend of covering early gives confidence to home‐backers. Also notable is that Northern Illinois has seen totals go under in its recent games, which might make the Over attractive for this matchup if bettors believe Mississippi State will push a fast pace.

NILL trend: Northern Illinois is 1-1 ATS so far in 2025; in road games they’ve shown some ability to keep it close, notably in their opener vs. Maryland and in other games where they weren’t heavily favored. Their road vs. spread record indicates that while wins are harder to come by, they tend to outperform expectations when matched up as underdogs.

MISSST trend: Mississippi State is also 2-0 ATS to start the season. Their wins over Southern Miss and Arizona State both came with them being favored by meaningful spreads, and they have covered those lines. Their offense has done enough and the defense has made key plays in presumably tight moments, giving confidence to those backing them at home.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

Northern Illinois vs. Mississippi State Odds

Remi is pouring through mountains of data on each team. In fact, anytime the Northern Illinois vs Mississippi State trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme temps seemingly never follow normal, predictable patterns.

Northern Illinois vs Mississippi State Opening Odds

NILL Moneyline: +1078
MISSST Moneyline: -2174
NILL Spread: +21.5
MISSST Spread: -21.5
Over/Under: 49.5

Northern Illinois vs Mississippi State Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-370
 
-9.5 (-110)
O 55.5 (-110)
U 55.5 (-110)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-108
-108
-1.5 (-105)
+1.5 (-115)
O 51.5 (-110)
U 51.5 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-225
+185
-6.5 (-110)
+6.5 (-110)
O 55.5 (-112)
U 55.5 (-108)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4000
+1600
-26.5 (-112)
+26.5 (-108)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+164
-198
+4.5 (-108)
-4.5 (-112)
O 49.5 (-115)
U 49.5 (-105)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1800
+1000
-21 (-115)
+21 (-105)
O 50.5 (-112)
U 50.5 (-108)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-395
+310
-10.5 (-108)
+10.5 (-112)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-290
+235
-7.5 (-105)
+7.5 (-115)
O 48.5 (-108)
U 48.5 (-112)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+114
-2.5 (-115)
+2.5 (-105)
O 58.5 (-112)
U 58.5 (-108)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-205
+170
-4.5 (-112)
+4.5 (-108)
O 63.5 (-108)
U 63.5 (-112)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1400
-3200
+25.5 (-110)
-25.5 (-110)
O 54.5 (-115)
U 54.5 (-105)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+230
-285
+7 (-105)
-7 (-115)
O 43.5 (-110)
U 43.5 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-500
+380
-12.5 (-108)
+12.5 (-112)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-180
+150
-3.5 (-108)
+3.5 (-112)
O 53.5 (-115)
U 53.5 (-105)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+600
-900
+17.5 (-110)
-17.5 (-110)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-625
 
-14.5 (-108)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+180
-218
+4.5 (-105)
-4.5 (-115)
O 54.5 (-108)
U 54.5 (-112)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-155
+3 (-112)
-3 (-108)
O 56.5 (-115)
U 56.5 (-105)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
-105
-115
+1.5 (-115)
-1.5 (-105)
O 56.5 (-112)
U 56.5 (-108)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+310
-395
+9.5 (-110)
-9.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-410
+320
-10.5 (-110)
+10.5 (-110)
O 49.5 (-105)
U 49.5 (-115)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-112)
-3 (-108)
O 61.5 (-112)
U 61.5 (-108)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+275
-345
+9.5 (-112)
-9.5 (-108)
O 39.5 (-108)
U 39.5 (-112)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-485
+370
-12.5 (-110)
+12.5 (-110)
O 47.5 (-108)
U 47.5 (-112)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+124
-148
+2.5 (-102)
-2.5 (-118)
O 48.5 (-112)
U 48.5 (-108)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-238
+195
-6 (-112)
+6 (-108)
O 53.5 (-112)
U 53.5 (-108)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+180
-218
+5.5 (-112)
-5.5 (-108)
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-102
-118
+1.5 (-115)
-1.5 (-105)
O 46.5 (-108)
U 46.5 (-112)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+455
-625
+15.5 (-108)
-15.5 (-112)
O 62.5 (-112)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+164
-198
+4.5 (-110)
-4.5 (-110)
O 53.5 (-115)
U 53.5 (-105)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-700
 
-16.5 (-108)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-155
+130
-3 (-110)
+3 (-110)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+114
-135
+2.5 (-110)
-2.5 (-110)
O 51.5 (-115)
U 51.5 (-105)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+205
-250
+6.5 (-108)
-6.5 (-112)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+102
 
+1.5 (-110)
 
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+340
 
+10.5 (-105)
 
O 50.5 (-112)
U 50.5 (-108)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+2800
-10000
+38.5 (-115)
-38.5 (-105)
O 56.5 (-108)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+154
-185
+4.5 (-110)
-4.5 (-110)
O 66.5 (-115)
U 66.5 (-105)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-270
+220
-7 (-105)
+7 (-115)
O 44.5 (-115)
U 44.5 (-105)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-650
+470
-15.5 (-110)
+15.5 (-110)
O 54.5 (-118)
U 54.5 (-102)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-108)
-33.5 (-112)
O 44.5 (-112)
U 44.5 (-108)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+280
-355
+8.5 (-108)
-8.5 (-112)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30.5 (-115)
-30.5 (-105)
O 45.5 (-105)
U 45.5 (-115)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 63.5 (-105)
U 63.5 (-115)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-625
+455
-14.5 (-105)
+14.5 (-115)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-142
+120
-2.5 (-115)
+2.5 (-105)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1400
-3200
+25.5 (-110)
-25.5 (-110)
O 55.5 (-102)
U 55.5 (-118)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+180
-218
+5.5 (-110)
-5.5 (-110)
O 46.5 (-112)
U 46.5 (-108)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-345
+275
-9.5 (-108)
+9.5 (-112)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+230
-285
+7.5 (-115)
-7.5 (-105)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+410
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-112)
U 49.5 (-108)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Northern Illinois Huskies vs. Mississippi State Bulldogs on September 20, 2025 at Davis Wade Stadium at Scott Field.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN