NC State vs Duke Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 20)

Updated: 2025-09-13T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

NC State enters this matchup as a 2.5-point underdog at Duke, with oddsmakers expecting a competitive game rather than a blowout. The over/under is set around 59 points, implying expectations for both teams to contribute offensively and for the scoring to be above average.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 20, 2025

Start Time: 4:00 PM EST​

Venue: Brooks Field at Wallace Wade Stadium​

Blue Devils Record: (1-2)

Wolfpack Record: (3-0)

OPENING ODDS

NCST Moneyline: +112

DUKE Moneyline: -133

NCST Spread: +2.5

DUKE Spread: -2.5

Over/Under: 59

NCST
Betting Trends

  • NC State is 2-0 straight up to start the season, but their ATS performance is mixed; they have covered in some games but not consistently. One of their earlier games shows them favored by “NC State –2.5” vs. Virginia with a total of 52.5, indicating moderate expectations.

DUKE
Betting Trends

  • Duke has struggled to cover spreads to date, entering this matchup with an 0-3 ATS record in their first three games. Despite having talent on offense, they have yet to satisfy betting expectations in terms of covering, especially when favorites or in close contests.

MATCHUP TRENDS

  • The 2.5-point spread in favor of Duke suggests the market believes Duke has a slight edge at home, but also that the game is expected to be close. The relatively high Over/Under near 59 points hints that bettors expect both offenses to have opportunities and potentially some defensive lapses. Head-to-head historical data shows that in their recent matchups, NC State has an ATS win rate of 60% and games between the two tend to go Over in total points about 60% of the time.

NCST vs. DUKE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: W. Grimes under 46.5 Receiving Yards.

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NC State vs Duke Prediction & Odds:
Free CFB Betting Insights for 9/20/25

The September 20, 2025, matchup between NC State and Duke sets up as a fascinating early-season ACC battle that carries weight not only for bragging rights in the state of North Carolina but also for positioning in a league that often sees tight races in the middle of the pack. NC State comes in with momentum, having started the season with confidence and results that show both balance and discipline, while Duke is still searching for consistency after a shaky start that has left them winless against the spread despite flashes of promise offensively. The Wolfpack have leaned on a combination of steady quarterback play, a reliable ground game, and a defense that bends but rarely breaks, allowing them to manage clock, keep drives alive, and frustrate opponents by limiting explosive plays. Their ability to win on the line of scrimmage has been a difference-maker so far, and against Duke, they will again rely on trench dominance to control tempo and keep their offense in rhythm. Duke, meanwhile, has the talent to score quickly and put pressure on opposing defenses, but their struggles to finish drives and a defense that has too often yielded big plays at key moments have kept them from converting opportunities into results that satisfy expectations. Their 0-3 ATS record to start the season reflects a team that has not delivered in proportion to its perceived talent, and facing an NC State squad that thrives on capitalizing on mistakes, that trend could be problematic if it continues.

From a tactical standpoint, the game will hinge on whether Duke’s offense can sustain consistency against a disciplined NC State defense, and whether the Blue Devils can finally find a way to slow down an opponent on third downs. The line has Duke favored by less than a field goal, a sign that oddsmakers and bettors alike see this as close, and the total hovering around 59 points suggests that scoring opportunities should be available for both sides. For NC State, the keys will be avoiding turnovers, keeping Duke’s crowd quiet with sustained drives, and using their physicality to grind down the Blue Devils in the second half. For Duke, protecting the football, taking advantage of red-zone chances, and finding more balance between their running and passing game will be crucial to covering the spread and getting a much-needed win. Ultimately, this matchup feels like a test of execution and discipline: if NC State continues its early-season trend of steady, mistake-free football, they have the edge to pull the upset outright, but if Duke harnesses its home-field advantage and finally plays to its potential, they could notch a victory that would stabilize their season.

NC State Wolfpack CFB Preview

The NC State Wolfpack head into Durham on September 20, 2025, eager to extend their strong start to the season and prove that their early success is not a fluke but the product of a disciplined and well-balanced team built to compete in the ACC. Entering with momentum and a 2-1 ATS record that suggests bettors can trust them to deliver as underdogs, the Wolfpack bring with them an identity centered on physicality in the trenches, a balanced offensive attack, and a defense that has shown the ability to make timely stops. Offensively, NC State has leaned on a ground game that can churn out consistent yardage, setting up manageable third downs and opening opportunities for their quarterback to distribute the ball effectively to a receiving corps that has improved in separation and execution. The offensive line has been a cornerstone of their success, giving both stability and confidence to the play calling, and against Duke’s defense that has struggled to contain explosive plays and win third-down situations, the Wolfpack will see opportunities to sustain long drives and control time of possession. On defense, NC State prides itself on discipline and tackling, two traits that will be essential against Duke’s offense, which has shown flashes of quick-strike capability but has lacked consistency.

The Wolfpack secondary will need to hold up against deep shots, but the pass rush has been strong enough to disrupt timing, and their ability to generate pressure without overcommitting will be key in forcing Duke into mistakes. Road games are always a challenge, and Wallace Wade Stadium can provide energy for the Blue Devils, but NC State has already shown composure on the road and will look to carry that into this matchup. Special teams could give them another edge, as NC State has been efficient in the kicking game and disciplined in coverage, limiting hidden-yardage mistakes that often swing close contests. From a betting perspective, NC State is viewed as a live underdog at +2.5, and their track record suggests that if they can keep the game close into the second half, they are more than capable of covering or even pulling off the outright win. Their formula will be straightforward: establish the run early, force Duke into uncomfortable down-and-distance situations, and avoid giving away field position with turnovers or penalties. If they execute with the same poise and efficiency they’ve displayed so far this season, the Wolfpack have every reason to believe they can not only challenge Duke but also walk away with another important victory that keeps them undefeated and positions them as a dark horse in the ACC.

NC State enters this matchup as a 2.5-point underdog at Duke, with oddsmakers expecting a competitive game rather than a blowout. The over/under is set around 59 points, implying expectations for both teams to contribute offensively and for the scoring to be above average.  NC State vs Duke AI Prediction: Free CFB Betting Insights for Sep 20. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Duke Blue Devils CFB Preview

The Duke Blue Devils return to Wallace Wade Stadium on September 20, 2025, with urgency and opportunity as they host in-state rival NC State in a game that feels like an early-season crossroads. At 1-2 overall and 0-3 against the spread, Duke has underwhelmed relative to preseason expectations, but this matchup provides the perfect chance to reset in front of their home crowd and prove that they can deliver in conference play. Offensively, Duke has the talent to move the ball, with their quarterback showing flashes of rhythm in the passing game and a supporting cast of skill players capable of creating explosive plays in space, but inconsistency in sustaining drives and finishing in the red zone has plagued them. The offensive line will be under pressure to hold up against a disciplined NC State front seven that thrives on winning battles at the line of scrimmage, and how well they establish balance between the run and pass will determine whether they can dictate tempo. Defensively, Duke has been the source of the most concern, allowing opponents to convert critical third downs and failing to contain explosive plays at key moments, which has left them vulnerable despite competitive stretches of football.

To reverse that trend, the Blue Devils must get more out of their pass rush, forcing NC State’s quarterback into quicker decisions while tightening coverage to prevent easy completions that extend drives. Home-field advantage should not be underestimated; the energy of the crowd and the comfort of playing in Durham could give Duke the spark they need, especially if they can get off to a fast start. Special teams execution will also play a role, as Duke cannot afford hidden yardage mistakes or missed opportunities in what oddsmakers project as a close game with only a 2.5-point spread. From a betting perspective, Duke has been disappointing for backers so far, but as slight home favorites, they represent a team with upside if they finally deliver a complete game on both sides of the ball. The key will be discipline—avoiding turnovers, minimizing penalties, and staying sharp in late-game situations where they have faltered in the past. If the Blue Devils use their speed on offense to stress NC State’s defense and their defensive unit can elevate to at least contain the Wolfpack’s balanced attack, they are well positioned to secure not only a win but potentially their first cover of the season. This is a pivotal moment for Duke to show that they can rise to the occasion, defend their home turf, and reestablish themselves as a credible threat in the ACC despite their rocky start.

NC State vs. Duke Prop Picks (AI)

Remi is pouring through mountains of stats on each team. In fact, anytime the Wolfpack and Blue Devils play there’s always several intriguing trends to key in on. Not to mention games played at Brooks Field at Wallace Wade Stadium in Sep rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: W. Grimes under 46.5 Receiving Yards.

NC State vs. Duke Prediction (AI)

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Remi, our AI sports genius, has been pouring over millions of data from every facet between the Wolfpack and Blue Devils and using recursive machine learning and kick-ass AI to analyze the data to a single cover probability.

The Algorithm has been most focused on the linear correlation of factor knucklehead sportsbettors regularly put on Duke’s strength factors between a Wolfpack team going up against a possibly unhealthy Blue Devils team. Trends look to say the true game analytics might reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI NC State vs Duke picks, computer picks Wolfpack vs Blue Devils, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Wolfpack Betting Trends

NC State is 2-0 straight up to start the season, but their ATS performance is mixed; they have covered in some games but not consistently. One of their earlier games shows them favored by “NC State –2.5” vs. Virginia with a total of 52.5, indicating moderate expectations.

Blue Devils Betting Trends

Duke has struggled to cover spreads to date, entering this matchup with an 0-3 ATS record in their first three games. Despite having talent on offense, they have yet to satisfy betting expectations in terms of covering, especially when favorites or in close contests.

Wolfpack vs. Blue Devils Matchup Trends

The 2.5-point spread in favor of Duke suggests the market believes Duke has a slight edge at home, but also that the game is expected to be close. The relatively high Over/Under near 59 points hints that bettors expect both offenses to have opportunities and potentially some defensive lapses. Head-to-head historical data shows that in their recent matchups, NC State has an ATS win rate of 60% and games between the two tend to go Over in total points about 60% of the time.

NC State vs. Duke Game Info

NC State vs Duke starts on September 20, 2025 at 4:00 PM EST.

Venue: Brooks Field at Wallace Wade Stadium.

Spread: Duke -2.5
Moneyline: NC State +112, Duke -133
Over/Under: 59

NC State: (3-0)  |  Duke: (1-2)

Remi's searched hard and found the best prop for this matchup: W. Grimes under 46.5 Receiving Yards.. Prices move—always shop for the best number.

The 2.5-point spread in favor of Duke suggests the market believes Duke has a slight edge at home, but also that the game is expected to be close. The relatively high Over/Under near 59 points hints that bettors expect both offenses to have opportunities and potentially some defensive lapses. Head-to-head historical data shows that in their recent matchups, NC State has an ATS win rate of 60% and games between the two tend to go Over in total points about 60% of the time.

NCST trend: NC State is 2-0 straight up to start the season, but their ATS performance is mixed; they have covered in some games but not consistently. One of their earlier games shows them favored by “NC State –2.5” vs. Virginia with a total of 52.5, indicating moderate expectations.

DUKE trend: Duke has struggled to cover spreads to date, entering this matchup with an 0-3 ATS record in their first three games. Despite having talent on offense, they have yet to satisfy betting expectations in terms of covering, especially when favorites or in close contests.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

NC State vs. Duke Odds

AI algorithm Remi is pouring through loads of stats on each team. In fact, anytime the NC State vs Duke trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments rarely follow normal, predictable patterns.

NC State vs Duke Opening Odds

NCST Moneyline: +112
DUKE Moneyline: -133
NCST Spread: +2.5
DUKE Spread: -2.5
Over/Under: 59

NC State vs Duke Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-360
 
-9.5 (-108)
O 55.5 (-108)
U 55.5 (-112)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-110
-110
-1.5 (-102)
+1.5 (-118)
O 50.5 (-112)
U 50.5 (-108)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-230
+190
-6.5 (-112)
+6.5 (-108)
O 55.5 (-112)
U 55.5 (-108)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4000
+1600
-26.5 (-112)
+26.5 (-108)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+164
-198
+4.5 (-110)
-4.5 (-110)
O 50.5 (-108)
U 50.5 (-112)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1800
+1000
-21.5 (-105)
+21.5 (-115)
O 50.5 (-108)
U 50.5 (-112)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-395
+310
-10.5 (-108)
+10.5 (-112)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-285
+230
-7.5 (-105)
+7.5 (-115)
O 48.5 (-108)
U 48.5 (-112)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+114
-2.5 (-112)
+2.5 (-108)
O 58.5 (-112)
U 58.5 (-108)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-205
+170
-4.5 (-112)
+4.5 (-108)
O 63.5 (-108)
U 63.5 (-112)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1400
-3200
+25.5 (-115)
-25.5 (-105)
O 54.5 (-115)
U 54.5 (-105)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+240
-298
+7.5 (-112)
-7.5 (-108)
O 43.5 (-110)
U 43.5 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-455
+350
-12.5 (-108)
+12.5 (-112)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-170
+142
-3.5 (-105)
+3.5 (-115)
O 54.5 (-105)
U 54.5 (-115)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+625
-950
+17.5 (-110)
-17.5 (-110)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-625
 
-14.5 (-108)
O 62.5 (-115)
U 62.5 (-105)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+170
-205
+4.5 (-105)
-4.5 (-115)
O 54.5 (-108)
U 54.5 (-112)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+124
-148
+3 (-112)
-3 (-108)
O 56.5 (-115)
U 56.5 (-105)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
-105
-115
+1.5 (-115)
-1.5 (-105)
O 56.5 (-112)
U 56.5 (-108)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+285
-360
+9.5 (-110)
-9.5 (-110)
O 47.5 (-108)
U 47.5 (-112)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-395
+310
-10.5 (-110)
+10.5 (-110)
O 49.5 (-105)
U 49.5 (-115)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-112)
-3 (-108)
O 61.5 (-112)
U 61.5 (-108)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+275
-345
+8.5 (-108)
-8.5 (-112)
O 39.5 (-108)
U 39.5 (-112)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-455
+350
-12.5 (-110)
+12.5 (-110)
O 47.5 (-108)
U 47.5 (-112)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+124
-148
+2.5 (-102)
-2.5 (-118)
O 48.5 (-112)
U 48.5 (-108)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-230
+190
-6 (-110)
+6 (-110)
O 53.5 (-112)
U 53.5 (-108)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+185
-225
+5.5 (-112)
-5.5 (-108)
O 41.5 (-105)
U 41.5 (-115)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-108
-112
+1.5 (-115)
-1.5 (-105)
O 46.5 (-108)
U 46.5 (-112)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+455
-625
+15.5 (-108)
-15.5 (-112)
O 62.5 (-112)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+164
-198
+4.5 (-110)
-4.5 (-110)
O 53.5 (-115)
U 53.5 (-105)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-675
 
-16.5 (-108)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-148
+124
-3 (-105)
+3 (-115)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+120
-142
+2.5 (-105)
-2.5 (-115)
O 52.5 (-105)
U 52.5 (-115)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+205
-250
+6.5 (-108)
-6.5 (-112)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+102
 
+1.5 (-110)
 
O 41.5 (-108)
U 41.5 (-112)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+340
 
+10.5 (-105)
 
O 50.5 (-112)
U 50.5 (-108)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+3000
-10000
+37.5 (-102)
-37.5 (-118)
O 56.5 (-108)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+160
-192
+4 (-108)
-4 (-112)
O 66.5 (-115)
U 66.5 (-105)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-265
+215
-7 (-105)
+7 (-115)
O 45.5 (-105)
U 45.5 (-115)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-650
+470
-15.5 (-110)
+15.5 (-110)
O 55.5 (-102)
U 55.5 (-118)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+32.5 (-105)
-32.5 (-115)
O 44.5 (-112)
U 44.5 (-108)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+280
-355
+8.5 (-108)
-8.5 (-112)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+2000
-10000
+30.5 (-115)
-30.5 (-105)
O 45.5 (-105)
U 45.5 (-115)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 63.5 (-105)
U 63.5 (-115)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-600
+440
-14 (-115)
+14 (-105)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-142
+120
-2.5 (-115)
+2.5 (-105)
O 47.5 (-115)
U 47.5 (-105)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1300
-2800
+25.5 (-110)
-25.5 (-110)
O 55.5 (-102)
U 55.5 (-118)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+180
-218
+5.5 (-110)
-5.5 (-110)
O 46.5 (-112)
U 46.5 (-108)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-345
+275
-9.5 (-108)
+9.5 (-112)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+230
-285
+7.5 (-115)
-7.5 (-105)
O 46.5 (-115)
U 46.5 (-105)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+410
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-112)
U 49.5 (-108)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-265
+215
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-205
+168
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-450
+340
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+146
-178
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers NC State Wolfpack vs. Duke Blue Devils on September 20, 2025 at Brooks Field at Wallace Wade Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN