UConn vs Syracuse Prediction — AI Finds CAN'T MISS CFB Lines & Props (Sep 06)

Updated: 2025-08-30T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The UConn Huskies travel to the JMA Wireless Dome to face the Syracuse Orange on September 6, 2025, in an early-season ACC matchup featuring a renewed in-state rivalry. Syracuse enters as a 6.5 to 7.5-point favorite, depending on the sportsbook, indicating expectations for them to control at home while still acknowledging UConn’s upward momentum after a strong opening performance.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Sep 06, 2025

Start Time: 12:00 PM EST​

Venue: JMA Wireless Dome​

Orange Record: (0-1)

Huskies Record: (1-0)

OPENING ODDS

UCONN Moneyline: +204

CUSE Moneyline: -252

UCONN Spread: +6.5

CUSE Spread: -6.5

Over/Under: 58.5

UCONN
Betting Trends

  • UConn starts the 2025 campaign 1–0 ATS, having covered comfortably in their opener after a dominant 59–13 win over Central Connecticut State, highlighted by a school-record 638 yards of total offense.

CUSE
Betting Trends

  • Syracuse enters at 0–1 ATS, failing to cover in their 45–26 loss at Tennessee despite being favored, raising early questions about their ability to meet spread expectations.

MATCHUP TRENDS

  • Despite Syracuse’s favorite status, bettors are showing confidence in UConn—approximately 39% of spread wagers are backing the Huskies, hinting at belief that they can keep the game competitive.

UCONN vs. CUSE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: S. Angeli under 298.5 Passing Yards.

LIVE CFB ODDS

CFB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
325-240
VAULT
NET UNITS
(INCL VIG)
+395.4
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$39,540
EXECUTIVE
VS. SPREAD
1593-1364
EXECUTIVE
NET UNITS
(INCL VIG)
+371.9
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$37,192

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

UConn vs Syracuse Prediction & Odds:
Free CFB Betting Insights for 9/6/25

The September 6, 2025 matchup between the UConn Huskies and the Syracuse Orange at the JMA Wireless Dome revives a regional rivalry while also offering both teams an opportunity to make an early-season statement, as Syracuse seeks to rebound from a disappointing opener and UConn looks to build on the confidence gained from one of its most dominant offensive showings in program history, and oddsmakers have set the Orange as 6.5 to 7.5-point favorites, reflecting both their ACC pedigree and the recognition that UConn’s trajectory under Jim Mora cannot be overlooked. The Huskies stormed out of the gate in Week 1 with a 59–13 dismantling of Central Connecticut State, setting a school record with 638 total yards of offense, as quarterback Joe Fagnano showed command and poise in distributing the ball efficiently, running back Cam Edwards ripped off over 100 rushing yards with explosive burst, and receiver Skyler Bell tallied 135 yards and two touchdowns to headline a passing attack that looked polished and dangerous. That performance built on a 2024 season in which UConn went 9–4 and won the Fenway Bowl, signaling that Mora’s steady rebuild has transformed the Huskies from a bottom-tier independent to a competitive program capable of scaring Power Five opponents, and this matchup against an ACC foe provides an ideal platform to validate that progress. Syracuse, on the other hand, comes into this game licking its wounds after a 45–26 loss to Tennessee, a game in which they failed to cover the spread and struggled defensively to contain an SEC opponent that exploited mismatches downfield and forced the Orange offense into a catch-up mode that exposed inefficiencies.

For head coach Fran Brown, the task now is to recalibrate quickly, leveraging the athleticism and speed of his roster to ensure that Syracuse can dictate tempo at home rather than letting UConn establish rhythm, and the defense in particular will need to tighten coverage and improve tackling to avoid giving the Huskies’ skill players space to operate. Key matchups to watch include whether Syracuse’s front seven can disrupt Edwards and limit UConn’s ground game, forcing Fagnano into high-pressure passing downs, and whether the Orange’s offense can generate balance to challenge a UConn defense that, despite its strong opener, has not yet been tested by Power Five size and speed. Special teams could also play an outsized role, as UConn’s explosiveness in all phases was on display in Week 1, while Syracuse will aim to use the energy of the Dome crowd to spark momentum swings. From a betting standpoint, UConn’s 1–0 ATS mark contrasts with Syracuse’s 0–1 ATS, and the fact that nearly 40 percent of bettors are backing the Huskies reflects confidence that Mora’s squad can keep the game competitive if not outright spring the upset. Ultimately, this contest will come down to execution in the red zone, composure under pressure, and turnover margin, as both teams have the weapons to score but must avoid self-inflicted wounds that can shift momentum in a rivalry setting. If Syracuse can reestablish defensive discipline and leverage its home-field advantage, they should validate their favorite status, but if UConn can replicate the explosiveness and efficiency of their opener, the Huskies have every chance to push this game to the wire and possibly deliver a defining moment in their continued resurgence.

UConn Huskies CFB Preview

The UConn Huskies travel to the JMA Wireless Dome on September 6, 2025 with the belief that they can carry the momentum from their season-opening blowout into a rivalry matchup that represents both a measuring stick and an opportunity to solidify their rise under head coach Jim Mora, and while they enter as underdogs of 6.5 to 7.5 points, the confidence generated by their 59–13 thrashing of Central Connecticut State gives them every reason to believe they can compete with Syracuse. That opener was nothing short of historic for the Huskies, as they set a school record with 638 total yards of offense, with quarterback Joe Fagnano throwing with efficiency and command, completing passes to multiple receivers while avoiding mistakes, and running back Cam Edwards demonstrating explosiveness with over 100 rushing yards. Wideout Skyler Bell emerged as a star with 135 receiving yards and two touchdowns, stretching defenses vertically and giving UConn the kind of downfield threat that can punish opponents if they overcommit to stopping the run. The offensive line also deserves credit for controlling the trenches in Week 1, and they will need to replicate that performance against a Syracuse front that, while vulnerable against Tennessee, will be eager to prove itself in front of its home crowd. Defensively, UConn showed discipline and aggression in the opener, limiting CCSU’s opportunities and capitalizing on mistakes, but the test against an ACC offense with superior athletes will demand even sharper execution and tackling in space.

The secondary in particular will need to hold up under pressure, as Syracuse is likely to test them with deep routes and tempo to try and expose mismatches, and maintaining composure in high-leverage downs will be critical. Special teams could provide an additional edge, as UConn demonstrated explosiveness in that phase last season and continues to use it as a weapon to flip field position and create momentum. From a betting perspective, UConn begins the year 1–0 ATS and has drawn nearly 40 percent of spread bets in this matchup, a reflection of both their improved consistency under Mora and the skepticism surrounding Syracuse after its failure to cover in Week 1. For UConn, the formula to pulling the upset is straightforward but demanding: control time of possession with a balanced offensive attack, finish drives with touchdowns rather than field goals, avoid turnovers that hand Syracuse short fields, and win the hidden yardage battle through special teams. If they can sustain their offensive rhythm, protect Fagnano, and keep Edwards productive on the ground, the Huskies will have the opportunity to dictate tempo and keep the pressure on Syracuse for four quarters. While the odds remain stacked against them in an ACC venue, the Huskies are playing with confidence, resilience, and a clear identity, and a victory in this setting would not only validate their progress but also mark one of the most significant wins in program history, further accelerating Mora’s rebuild and cementing UConn as a program capable of standing toe-to-toe with Power Five opposition.

The UConn Huskies travel to the JMA Wireless Dome to face the Syracuse Orange on September 6, 2025, in an early-season ACC matchup featuring a renewed in-state rivalry. Syracuse enters as a 6.5 to 7.5-point favorite, depending on the sportsbook, indicating expectations for them to control at home while still acknowledging UConn’s upward momentum after a strong opening performance. UConn vs Syracuse AI Prediction: Free CFB Betting Insights for Sep 06. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Syracuse Orange CFB Preview

The Syracuse Orange return to the JMA Wireless Dome on September 6, 2025 to host the UConn Huskies in a matchup that comes at a crucial time for head coach Fran Brown’s program, as they look to bounce back from a 45–26 season-opening loss to Tennessee that left them 0–1 ATS and exposed flaws on both sides of the ball, and oddsmakers have given them a 6.5 to 7.5-point edge at home, a modest spread that reflects both their potential and the rising confidence in UConn’s growth under Jim Mora. For Syracuse, this game is about reasserting identity and discipline, particularly on defense, where breakdowns in coverage and lapses in tackling allowed Tennessee to capitalize on explosive plays and seize control of momentum, something the Orange cannot afford to repeat against a UConn team that put up a school-record 638 yards of total offense in its opener. The front seven must play with more aggression and precision, controlling the line of scrimmage and preventing Cam Edwards from finding rhythm on the ground, while the secondary must tighten assignments to contain Joe Fagnano and Skyler Bell, who combined for multiple long gains in Week 1. Offensively, Syracuse has shown flashes of explosiveness and creativity, and with a capable quarterback and versatile skill players, they have the weapons to test UConn’s defense, but consistency in execution and finishing drives will be paramount after stalling too often against Tennessee.

Playing at home inside the Dome provides a major advantage, as the crowd noise can disrupt visiting quarterbacks and elevate the Orange defense’s energy, and Brown will be counting on that environment to help his team impose itself early. Special teams execution will also need to sharpen, as UConn already demonstrated game-breaking potential in that phase, and Syracuse must avoid giving away hidden yards or field position that could swing momentum. From a betting perspective, Syracuse’s inability to cover in Week 1 has fueled doubts about their reliability as favorites, and with nearly 40 percent of wagers siding with UConn, this contest has become an early litmus test for whether the Orange can handle the pressure of being expected to win against an opponent that has built momentum. The keys for Syracuse will be to strike early offensively to prevent UConn from settling into its balanced attack, to maintain gap discipline and sure tackling on defense, and to avoid turnovers that could hand the Huskies short fields and easy points. If Syracuse can correct the issues that plagued them against Tennessee and execute with urgency, they should have the talent and home-field advantage to validate their favorite status and claim a confidence-building win. More broadly, this game offers the Orange an opportunity to prove that their setbacks in Week 1 were an aberration and that they remain capable of competing in the ACC, and a strong performance here would calm early skepticism, stabilize morale, and give them the momentum they need heading into tougher stretches of their schedule.

UConn vs. Syracuse Prop Picks (AI)

AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the Huskies and Orange play there’s always several intriguing observations to key in on. Not to mention games played at JMA Wireless Dome in Sep can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: S. Angeli under 298.5 Passing Yards.

UConn vs. Syracuse Prediction (AI)

Remi Robot Icon

Remi, our AI sports wizard, has been pouring over tons of data from every facet between the Huskies and Orange and using recursive machine learning and impressive AI to crunch the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most focused on the unproportionally assigned weight knucklehead sportsbettors tend to put on UConn’s strength factors between a Huskies team going up against a possibly rested Orange team. Trends look to say the true game analytics appear to reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CFB AI picks for FREE now.

Below is our current AI UConn vs Syracuse picks, computer picks Huskies vs Orange, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CFB 10/21 KENSAW@FIU UNLOCK THIS PICK 3 EXECUTIVE Locked EXECUTIVE
CFB 10/21 WKY@LATECH UNLOCK THIS PICK 2 INTEL Locked INTEL

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CFB schedule

Huskies Betting Trends

UConn starts the 2025 campaign 1–0 ATS, having covered comfortably in their opener after a dominant 59–13 win over Central Connecticut State, highlighted by a school-record 638 yards of total offense.

Orange Betting Trends

Syracuse enters at 0–1 ATS, failing to cover in their 45–26 loss at Tennessee despite being favored, raising early questions about their ability to meet spread expectations.

Huskies vs. Orange Matchup Trends

Despite Syracuse’s favorite status, bettors are showing confidence in UConn—approximately 39% of spread wagers are backing the Huskies, hinting at belief that they can keep the game competitive.

UConn vs. Syracuse Game Info

UConn vs Syracuse starts on September 06, 2025 at 12:00 PM EST.

Venue: JMA Wireless Dome.

Spread: Syracuse -6.5
Moneyline: UConn +204, Syracuse -252
Over/Under: 58.5

UConn: (1-0)  |  Syracuse: (0-1)

Remi's searched hard and found the best prop for this matchup: S. Angeli under 298.5 Passing Yards.. Prices move—always shop for the best number.

Despite Syracuse’s favorite status, bettors are showing confidence in UConn—approximately 39% of spread wagers are backing the Huskies, hinting at belief that they can keep the game competitive.

UCONN trend: UConn starts the 2025 campaign 1–0 ATS, having covered comfortably in their opener after a dominant 59–13 win over Central Connecticut State, highlighted by a school-record 638 yards of total offense.

CUSE trend: Syracuse enters at 0–1 ATS, failing to cover in their 45–26 loss at Tennessee despite being favored, raising early questions about their ability to meet spread expectations.

See our latest CFB picks and odds pages for 2025 to compare prices before you bet.

UConn vs. Syracuse Odds

Remi is pouring through tons of data on each line. In fact, anytime the UConn vs Syracuse trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable betting trends.

UConn vs Syracuse Opening Odds

UCONN Moneyline: +204
CUSE Moneyline: -252
UCONN Spread: +6.5
CUSE Spread: -6.5
Over/Under: 58.5

UConn vs Syracuse Live Odds

Games PTS ML SPR O/U
Oct 22, 2025 7:30PM EDT
MTSU Blue Raiders
Delaware Blue Hens
10/22/25 7:30PM
MTSU
DEL
 
-360
 
-9.5 (-105)
O 55 (-118)
U 55 (-107)
Oct 22, 2025 9:00PM EDT
Missouri State Bears
New Mexico State Aggies
10/22/25 9PM
MIZZST
NMEXST
-115
-105
-1 (-110)
+1 (-110)
O 51 (-110)
U 51 (-110)
Oct 23, 2025 7:30PM EDT
South Alabama Jaguars
Georgia State Panthers
10/23/25 7:30PM
SBAMA
GAST
-240
+185
-6.5 (-112)
+6.5 (-109)
O 56 (-110)
U 56 (-112)
Oct 24, 2025 7:00PM EDT
North Texas Mean Green
Charlotte 49ers
10/24/25 7PM
NOTEX
CHARLO
-4500
+1550
-26.5 (-110)
+26.5 (-110)
O 61.5 (-105)
U 61.5 (-115)
Oct 24, 2025 7:30PM EDT
California Golden Bears
Virginia Tech Hokies
10/24/25 7:30PM
CAL
VATECH
+160
-205
+4.5 (-110)
-4.5 (-110)
O 50 (-112)
U 50 (-110)
Oct 24, 2025 10:00PM EDT
Boise State Broncos
Nevada Wolf Pack
10/24/25 10PM
BOISE
NEVADA
-1700
+950
-21.5 (-110)
+21.5 (-110)
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 12:00PM EDT
Virginia Cavaliers
North Carolina Tar Heels
10/25/25 12PM
UVA
UNC
-400
+310
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Oct 25, 2025 12:00PM EDT
Bowling Green Falcons
Kent State Golden Flashes
10/25/25 12PM
BGREEN
KENT
-305
+240
-7.5 (-105)
+7.5 (-115)
O 48.5 (-110)
U 48.5 (-110)
Oct 25, 2025 12:00PM EDT
Rutgers Scarlet Knights
Purdue Boilermakers
10/25/25 12PM
RUT
PURDUE
-135
+115
-2.5 (-110)
+2.5 (-110)
O 58.5 (-110)
U 58.5 (-110)
Oct 25, 2025 12:00PM EDT
South Florida Bulls
Memphis Tigers
10/25/25 12PM
SFLA
MEMP
-210
+175
-5 (-110)
+5 (-110)
O 63.5 (-110)
U 63.5 (-110)
Oct 25, 2025 12:00PM EDT
UCLA Bruins
Indiana Hoosiers
10/25/25 12PM
UCLA
IND
+1200
-5000
+25.5 (-113)
-25.5 (-108)
O 54.5 (-115)
U 54.5 (-106)
Oct 25, 2025 12:00PM EDT
Northwestern Wildcats
Nebraska Cornhuskers
10/25/25 12PM
NWEST
NEB
+228
-285
+7 (-110)
-7 (-110)
O 43 (-110)
U 43 (-110)
Oct 25, 2025 12:00PM EDT
Ohio Bobcats
Eastern Michigan Eagles
10/25/25 12PM
OHIO
EMICH
-480
+360
-12.5 (-110)
+12.5 (-110)
O 59.5 (-110)
U 59.5 (-110)
Oct 25, 2025 12:00PM EDT
SMU Mustangs
Wake Forest Demon Deacons
10/25/25 12PM
SMU
WAKE
-175
+148
-3.5 (-110)
+3.5 (-110)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 12:00PM EDT
Syracuse Orange
Georgia Tech Yellow Jackets
10/25/25 12PM
CUSE
GATECH
+600
-1000
+17.5 (-112)
-17.5 (-109)
O 53.5 (-110)
U 53.5 (-110)
Oct 25, 2025 12:00PM EDT
App State Mountaineers
Old Dominion Monarchs
10/25/25 12PM
APPST
OLDDOM
 
-600
 
-14.5 (-110)
O 63 (-110)
U 63 (-110)
Oct 25, 2025 12:00PM EDT
Ole Miss Rebels
Oklahoma Sooners
10/25/25 12PM
OLEMISS
OKLA
+180
-220
+5 (-110)
-5 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 12:00PM EDT
Kansas State Wildcats
Kansas Jayhawks
10/25/25 12PM
KSTATE
KANSAS
+130
-155
+3 (-110)
-3 (-110)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 12:45PM EDT
Auburn Tigers
Arkansas Razorbacks
10/25/25 12:45PM
AUBURN
ARK
+100
-120
+1 (-110)
-1 (-110)
O 57 (-110)
U 57 (-110)
Oct 25, 2025 1:00PM EDT
Akron Zips
Buffalo Bulls
10/25/25 1PM
AKRON
BUFF
+285
-365
+9.5 (-110)
-9.5 (-110)
O 48 (-115)
U 48 (-105)
Oct 25, 2025 3:00PM EDT
UConn Huskies
Rice Owls
10/25/25 3PM
UCONN
RICE
-420
+320
-10.5 (-115)
+10.5 (-105)
O 49 (-110)
U 49 (-110)
Oct 25, 2025 3:00PM EDT
Utah State Aggies
New Mexico Lobos
10/25/25 3PM
UTAHST
NMEX
+130
-155
+3 (-110)
-3 (-110)
O 61.5 (-110)
U 61.5 (-110)
Oct 25, 2025 3:30PM EDT
Minnesota Golden Gophers
Iowa Hawkeyes
10/25/25 3:30PM
MINN
IOWA
+270
-345
+8.5 (-110)
-8.5 (-110)
O 39 (-110)
U 39 (-110)
Oct 25, 2025 3:30PM EDT
Alabama Crimson Tide
South Carolina Gamecocks
10/25/25 3:30PM
BAMA
SC
-480
+360
-12 (-110)
+12 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 3:30PM EDT
BYU Cougars
Iowa State Cyclones
10/25/25 3:30PM
BYU
IOWAST
+120
-152
+2.5 (-105)
-2.5 (-117)
O 48.5 (-115)
U 48.5 (-106)
Oct 25, 2025 3:30PM EDT
Temple Owls
Tulsa Golden Hurricane
10/25/25 3:30PM
TEMPLE
TULSA
-225
+185
-6 (-110)
+6 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 3:30PM EDT
Ball State Cardinals
Northern Illinois Huskies
10/25/25 3:30PM
BALLST
NILL
+175
-210
+5.5 (-110)
-5.5 (-110)
O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
Toledo Rockets
Washington State Cougars
10/25/25 3:30PM
TOLEDO
WASHST
-105
-115
+1 (-110)
-1 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
Florida Atlantic Owls
Navy Midshipmen
10/25/25 3:30PM
FAU
NAVY
+475
-750
+15.5 (-110)
-15.5 (-110)
O 62.5 (-113)
U 62.5 (-108)
Oct 25, 2025 3:30PM EDT
Illinois Fighting Illini
Washington Huskies
10/25/25 3:30PM
ILL
WASH
+162
-195
+4.5 (-110)
-4.5 (-110)
O 54 (-110)
U 54 (-110)
Oct 25, 2025 3:30PM EDT
Umass Minutemen
Central Michigan Chippewas
10/25/25 3:30PM
UMASS
CMICH
 
-800
 
-16.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 3:30PM EDT
San Diego State Aztecs
Fresno State Bulldogs
10/25/25 3:30PM
SDGST
FRESNO
-155
+130
-3 (-110)
+3 (-110)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 3:30PM EDT
Missouri Tigers
Vanderbilt Commodores
10/25/25 3:30PM
MIZZOU
VANDY
+118
-140
+2.5 (-110)
-2.5 (-110)
O 52.5 (-105)
U 52.5 (-115)
Oct 25, 2025 3:30PM EDT
NC State Wolfpack
Pittsburgh Panthers
10/25/25 3:30PM
NCST
PITT
+200
-260
+6.5 (-107)
-6.5 (-114)
O 56.5 (-110)
U 56.5 (-110)
Oct 25, 2025 3:30PM EDT
Western Michigan Broncos
Miami Ohio Redhawks
10/25/25 3:30PM
WMICH
MIAOH
+105
 
+1.5 (-110)
 
O 41 (-110)
U 41 (-110)
Oct 25, 2025 3:30PM EDT
UL Monroe Warhawks
USM Golden Eagles
10/25/25 3:30PM
MONROE
USM
+335
 
+11 (-110)
 
O 50.5 (-110)
U 50.5 (-110)
Oct 25, 2025 4:00PM EDT
Oklahoma State Cowboys
Texas Tech Red Raiders
10/25/25 4PM
OKLAST
TXTECH
+2800
-10000
+38.5 (-114)
-38.5 (-107)
O 56.5 (-110)
U 56.5 (-112)
Oct 25, 2025 4:00PM EDT
Baylor Bears
Cincinnati Bearcats
10/25/25 4PM
BAYLOR
CINCY
+162
-195
+4.5 (-110)
-4.5 (-110)
O 67.5 (-110)
U 67.5 (-110)
Oct 25, 2025 4:15PM EDT
Texas Longhorns
Mississippi State Bulldogs
10/25/25 4:15PM
TEXAS
MISSST
-267
+215
-7 (-105)
+7 (-115)
O 44.5 (-115)
U 44.5 (-105)
Oct 25, 2025 6:00PM EDT
TCU Horned Frogs
West Virginia Mountaineers
10/25/25 6PM
TCU
WVU
-750
+450
-15.5 (-110)
+15.5 (-110)
O 55.5 (-107)
U 55.5 (-114)
Oct 25, 2025 7:00PM EDT
Wisconsin Badgers
Oregon Ducks
10/25/25 7PM
WISC
OREG
 
 
+33.5 (-110)
-33.5 (-110)
O 44.5 (-110)
U 44.5 (-110)
Oct 25, 2025 7:00PM EDT
Louisiana Ragin Cajuns
Troy Trojans
10/25/25 7PM
UL
TROY
+270
-345
+9.5 (-110)
-9.5 (-110)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:00PM EDT
Stanford Cardinal
Miami Hurricanes
10/25/25 7PM
STNFRD
MIAMI
+4000
-30000
+30 (-109)
-30 (-112)
O 45.5 (-112)
U 45.5 (-109)
Oct 25, 2025 7:00PM EDT
Georgia Southern Eagles
Arkansas State Red Wolves
10/25/25 7PM
GASO
ARKST
+100
-120
+1.5 (-110)
-1.5 (-110)
O 62.5 (-110)
U 62.5 (-110)
Oct 25, 2025 7:30PM EDT
Michigan Wolverines
Michigan State Spartans
10/25/25 7:30PM
MICH
MICHST
-650
+460
-14.5 (-115)
+14.5 (-105)
O 48 (-110)
U 48 (-110)
Oct 25, 2025 7:30PM EDT
Texas A&M Aggies
LSU Tigers
10/25/25 7:30PM
TEXAM
LSU
-145
+122
-2.5 (-115)
+2.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Oct 25, 2025 7:30PM EDT
Boston College Eagles
Louisville Cardinals
10/25/25 7:30PM
BC
LVILLE
+1350
-3500
+25.5 (-110)
-25.5 (-110)
O 55 (-110)
U 55 (-110)
Oct 25, 2025 7:30PM EDT
Colorado State Rams
Wyoming Cowboys
10/25/25 7:30PM
COLOST
WYO
+185
-225
+5.5 (-110)
-5.5 (-110)
O 46.5 (-110)
U 46.5 (-110)
Oct 25, 2025 7:45PM EDT
Tennessee Volunteers
Kentucky Wildcats
10/25/25 7:45PM
TENN
UK
-360
+275
-9.5 (-107)
+9.5 (-114)
O 54.5 (-110)
U 54.5 (-110)
Oct 25, 2025 8:00PM EDT
Houston Cougars
Arizona State Sun Devils
10/25/25 8PM
HOU
ARIZST
+235
-310
+7.5 (-115)
-7.5 (-107)
O 47 (-110)
U 47 (-110)
Oct 25, 2025 10:15PM EDT
Colorado Buffaloes
Utah Utes
10/25/25 10:15PM
COLO
UTAH
+400
-550
+13.5 (-110)
-13.5 (-110)
O 49.5 (-110)
U 49.5 (-110)
Oct 28, 2025 8:00PM EDT
James Madison Dukes
Texas State Bobcats
10/28/25 8PM
JMAD
TEXST
-275
+220
-7.5 (-104)
+7.5 (-118)
O 60.5 (-112)
U 60.5 (-108)
Oct 30, 2025 7:30PM EDT
Tulane Green Wave
UTSA Roadrunners
10/30/25 7:30PM
TULANE
UTSA
-200
+164
-5.5 (-110)
+5.5 (-110)
O 52.5 (-112)
U 52.5 (-108)
Nov 1, 2025 12:00PM EDT
Penn State Nittany Lions
Ohio State Buckeyes
11/1/25 12PM
PSU
OHIOST
+660
-1050
+17.5 (-115)
-17.5 (-105)
O 47.5 (-110)
U 47.5 (-110)
Nov 1, 2025 12:00PM EDT
Miami Hurricanes
SMU Mustangs
11/1/25 12PM
MIAMI
SMU
-430
+330
-10.5 (-110)
+10.5 (-110)
O 51.5 (-110)
U 51.5 (-110)
Nov 1, 2025 12:00PM EDT
Oklahoma Sooners
Tennessee Volunteers
11/1/25 12PM
OKLA
TENN
-105
-114
+1.5 (-114)
-1.5 (-106)
O 53.5 (-112)
U 53.5 (-108)
Nov 1, 2025 12:00PM EDT
Vanderbilt Commodores
Texas Longhorns
11/1/25 12PM
VANDY
TEXAS
+150
-182
+3.5 (-106)
-3.5 (-114)
O 45.5 (-110)
U 45.5 (-110)
Nov 1, 2025 3:30PM EDT
Georgia Bulldogs
Florida Gators
11/1/25 3:30PM
UGA
FLA
-300
+240
-7.5 (-110)
+7.5 (-110)
O 50.5 (-112)
U 50.5 (-108)

CFB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers UConn Huskies vs. Syracuse Orange on September 06, 2025 at JMA Wireless Dome.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CFB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
FSU@STNFRD STNFRD +18 56.6% 6 WIN
WASHST@UVA WASHST +17.5 58.8% 8 WIN
NEVADA@NMEX NEVADA +13.5 57.8% 7 WIN
TEXAS@UK ARCH MANNING UNDER 1.5 PASS TD 56.1% 6 WIN
ARMY@TULANE ARMY +10 55.3% 5 WIN
SJST@UTAHST SJST +4 54.4% 4 LOSS
LVILLE@MIAMI LVILLE +12.5 56.5% 6 WIN
LVILLE@MIAMI CJ DANIELS UNDER 4.5 RECEPTIONS 54.4 4 LOSS
DEL@JAXST DEL -2.5 57.6% 6 LOSS
UTEP@SAMST UTEP -2.5 53.9% 3 WIN
FIU@WKY FIU +10.5 54.6% 4 WIN
ARKST@SALA ARKST +7.5 54.5% 4 WIN
ARKST@SALA JAYLEN RAYNOR UNDER 40.5 LONGEST PASS COMP 53.3% 3 WIN
SJST@WYO SJST -120 59.8% 7 LOSS
UMASS@KENTST KENTST -135 60.2% 6 WIN
NOILL@EMICH EMICH +2.5 53.9% 3 WIN
BYU@ARIZ ARIZ +2.5 54.2% 3 LOSS
OKLA@TEXAS OKLA +2.5 54.7% 4 LOSS
NMEX@BOISE NMEX +16.5 56.4% 6 WIN
WAKE@OREGST WAKE -2.5 56.7% 6 WIN
ULMON@COASTAL ULMON -2.5 56.8% 6 LOSS
IOWA@WISC WISC +4 54.8% 4 LOSS
TOLEDO@BGREEN TOLEDO -10 56.3% 6 LOSS
SFLA@NOTEX SFLA +2.5 54.3% 4 WIN
FRESNO@COLOST RICHIE ANDERSON III LONGEST RECEPTION UNDER 16.5 54.4% 4 LOSS
JAXST@SAMST SAMST +7.5 55.3% 5 WIN
USM@GAS GAS +3.5 57.4% 7 WIN
LIB@UTEP UTEP +2 54.5% 4 LOSS
SALA@TROY SALA -118 55.2% 4 LOSS
TULSA@MEMP MEMP -20.5 53.8% 3 WIN
JMAD@GAST GAST +20.5 54.6% 4 WIN
WAKE@VATECH VATECH -5.5 56.6% 6 LOSS
UNLV@WYO WYO +4.5 55.5% 5 LOSS
PSU@UCLA PSU -24.5 56.3% 6 LOSS
TXSTSM@ARKST TXSTSM -13 56.7% 6 LOSS
UVA@LVILLE ISAAC BROWN OVER 70.5 RUSH YDS 56.6% 6 LOSS
WVU@BYU WVU +20.5 54.7% 4 WIN
SAMST@NMEXST SAMST -1.5 54.1% 3 LOSS
EMICH@CMICH CMICH -148 62.8% 7 WIN
SDGST@NOILL SDGST -118 55.7% 3 WIN
BAMA@GEORGIA GEORGIA -125 58.7% 7 LOSS
TENN@MISSST MISSST +7.5 54.3% 4 WIN
UK@SC SC -5.5 54.8% 4 WIN
WKY@MIZZST MIZZST +4.5 55.6% 6 LOSS
JAXST@USM USM -3.5 56.0% 5 WIN
NMEXST@NMEX NMEX -14.5 56.9% 6 WIN
ARIZ@IOWAST ROCCO BECHT UNDER 1.5 PASS TDS 55.5% 5 WIN
TCU@ARIZST JOSH HOOVER PASS YDS UNDER 287.5 53.4% 3 WIN
ARIZST@BAYLOR BAYLOR -130 58.4% 6 LOSS
WYO@COLO WYO +13.5 54.1% 3 LOSS
TULANE@OLEMISS MISS -11.5 54.3% 4 WIN