Mississippi State vs South Carolina Prediction — AI Finds CAN'T MISS CBB Lines & Props (Feb 21)
Updated: 2026-02-19T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

GAME INFO
Date: Feb 21, 2026
Start Time:
Venue: Colonial Life Arena, Columbia, SC
Gamecocks Record:
Bulldogs Record:
OPENING ODDS
MISSST Moneyline:
SC Moneyline:
MISSST Spread:
SC Spread:
Over/Under:
MISSST
Betting Trends
SC
Betting Trends
MATCHUP TRENDS
MISSST vs. SC
Best Prop Bet
LIVE CBB ODDS
CBB ODDS COMPARISON
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Mississippi State vs South Carolina Prediction & Odds:
Free CBB Betting Insights for 2/21/26
Mississippi State Bulldogs CBB Preview

Credit: USA TODAY/IMAGN
South Carolina Gamecocks CBB Preview
Mississippi State vs. South Carolina Prop Picks (AI)
Mississippi State vs. South Carolina Prediction (AI)

Remi, our AI sports wizard, has been pouring over mountains of data from every angle between the Bulldogs and Gamecocks and using recursive machine learning and impressive AI to boil down the data to a single cover probability.
The Algorithm has been most watching on the trending factor emotional bettors often put on player performance factors between a Bulldogs team going up against a possibly strong Gamecocks team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CBB AI picks for FREE now.
Below is our current AI Mississippi State vs South Carolina picks, computer picks Bulldogs vs Gamecocks, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
---|---|---|---|---|---|---|
ACTIVE PICKS LOCKED - SEE NOW |
These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CBB schedule.
Bulldogs Betting Trends
Gamecocks Betting Trends
Bulldogs vs. Gamecocks Matchup Trends
Mississippi State vs. South Carolina Game Info
What time does Mississippi State vs South Carolina start on February 21, 2026?
Mississippi State vs South Carolina starts on February 21, 2026 at .
Where is Mississippi State vs South Carolina being played?
Venue: Colonial Life Arena, Columbia, SC.
What are the opening odds for Mississippi State vs South Carolina?
Spread: South Carolina
Moneyline: Mississippi State , South Carolina
Over/Under:
What are the records for Mississippi State vs South Carolina?
Mississippi State: | South Carolina:
What is the AI best bet for Mississippi State vs South Carolina?
. Prices move—always shop for the best number.
What are Mississippi State trending bets?
MISSST trend:
What are South Carolina trending bets?
SC trend:
Where can I find AI Picks for Mississippi State vs South Carolina?
See our latest CBB picks and odds pages for 2026 to compare prices before you bet.
Mississippi State vs. South Carolina Odds
Remi is pouring through mountains of stats on each team. In fact, anytime the Mississippi State vs South Carolina trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme altitude seemingly never follow normal, predictable patterns.
Mississippi State vs South Carolina Opening Odds
MISSST Moneyline:
SC Moneyline:
MISSST Spread:
SC Spread:
Over/Under:
Mississippi State vs South Carolina Live Odds
Games | PTS | ML | SPR | O/U |
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CBB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Mississippi State Bulldogs vs. South Carolina Gamecocks on February 21, 2026 at Colonial Life Arena, Columbia, SC.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CBB odds pages, and compare prices before you place a bet.
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LEAN | %WIN | UNITS | RESULT |
---|---|---|---|---|
DRAKE@MIZZOU | DRAKE +6.5 | 53.50% | 2 | WIN |
XAVIER@TEXAS | XAVIER -2.5 | 53.40% | 2 | WIN |
UAB@MEMP | MEMP -3.5 | 54.00% | 2 | WIN |
LVILLE@DUKE | LVILLE +6.5 | 53.10% | 2 | LOSS |
ECU@UAB | UAB -5 | 53.60% | 2 | WIN |
PURDUE@MICH | MICH +3 | 54.60% | 3 | WIN |
CLEM@LVILLE | CLEM -120 | 56.10% | 3 | LOSS |
COL@HOU | ANDREJ JAKIMOVSKI PTS + REB + AST - UNDER 15.5 | 53.70% | 2 | LOSS |
FORD@GWASH | FORD +7 | 53.80% | 2 | WIN |
SEATTLE@ABIL | ABIL +6 | 54.50% | 3 | WIN |
BAMAST@TEXSOU | BAMAST -110 | 55.40% | 4 | WIN |
OHIO@TOLEDO | TOLEDO +3 | 56.70% | 4 | WIN |
UVA@GATECH | GATECH +1.5 | 53.70% | 2 | WIN |
COLO@WVU | COLO +7.5 | 53.20% | 2 | WIN |
USC@RUT | USC -115 | 54.00% | 2 | WIN |
TEXAS@VANDY | VANDY -130 | 56.50% | 3 | LOSS |
BUTLER@PROV | BUTLER -115 | 55.20% | 3 | WIN |
IDAHO@MONTANA | MONTANA -6 | 53.50% | 2 | WIN |
TROY@JMAD | TROY -125 | 55.60% | 2 | WIN |
BELMONT@DRAKE | DRAKE -7.5 | 53.50% | 2 | LOSS |
UCSD@UCDAV | UCSD -12.5 | 53.40% | 2 | LOSS |
SIUE@SEMO | SEMO -2.5 | 54.80% | 3 | LOSS |
ALCORN@ARKPB | ARKPB +6.5 | 56.00% | 4 | WIN |
NORFLK@HOWARD | HOWARD +5.5 | 53.70% | 2 | LOSS |
NKY@CLEVST | NKY +4.5 | 54.40% | 3 | LOSS |
STNFRD@ND | STNFRD -125 | 56.40% | 3 | LOSS |
TENN@OLEMISS | OLEMISS +2.5 | 54.30% | 3 | WIN |
LSALLE@GMASON | GMASON -12 | 54.30% | 3 | LOSS |
PITT@NCST | NCST +2.5 | 56.70% | 4 | WIN |
IND@OREG | OREG -6.5 | 53.60% | 2 | WIN |
FSU@UVA | UVA -4 | 54.40% | 3 | LOSS |
ARK@VANDY | ARK +7.5 | 54.40% | 3 | WIN |
SDGST@UNLV | UNLV +2.5 | 54.10% | 3 | WIN |
EKTY@JVILLE | JVILLE -135 | 58.90% | 3 | WIN |
MANHAT@NIAGARA | MANHAT -115 | 54.70% | 3 | WIN |
MEMP@UAB | MEMP -115 | 54.90% | 3 | WIN |
ILL@MICH | MICH -2.5 | 56.00% | 4 | LOSS |
OKLA@OLEMISS | OKLA +7.5 | 54.50% | 3 | WIN |
ARIZST@UTAH | ARIZST +8.5 | 54.60% | 3 | LOSS |
GC@SEATTLE | GC -110 | 55.00% | 3 | WIN |
PENN@CLMBIA | CLMBIA -122 | 57.50% | 4 | LOSS |
IONA@NIAGARA | NIAGARA +1.5 | 54.30% | 3 | LOSS |
MARIST@SACHRT | SACHRT -120 | 55.40% | 3 | WIN |
CLEVST@WRIGHT | CLEVST +1.5 | 54.30% | 3 | LOSS |
NDAK@STTHOM | STTHOM -10 | 54.30% | 3 | WIN |
USD@WASHST | WASHST -12.5 | 55.20% | 4 | LOSS |
CSBAK@LBEACH | CSBAK -130 | 59.70% | 4 | WIN |
BU@LEHIGH | LEHIGH -135 | 57.70% | 3 | LOSS |
DUQ@LSALLE | DUQ -125 | 56.70% | 3 | WIN |
BYU@ARIZST | ARIZST +7.5 | 54.60% | 3 | LOSS |
UTAHST@BOISE | BOISE -4 | 55.50% | 4 | WIN |