Detroit Mercy vs DePaul Prediction — AI Finds CAN'T MISS CBB Lines & Props (Nov 23)

Updated: 2025-11-21T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Detroit Mercy Titans travel to face the DePaul Blue Demons on November 23, 2025, in a matchup that pits Detroit Mercy’s rebuilding roster and youth against DePaul’s effort to solidify progress under a newer coaching regime. With DePaul at home and seeking to enforce structure, and Detroit Mercy arriving with few expectations but the potential to disrupt, this game may turn on rebounding battles, transition defense, and which team best manages its energy across the full 40 minutes.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Nov 23, 2025

Start Time: 7:00 PM EST​

Venue: Wintrust Arena​

Blue Demons Record: (3-2)

Titans Record: (1-5)

OPENING ODDS

DTROIT Moneyline: +1375

DEPAUL Moneyline: -3226

DTROIT Spread: +20.5

DEPAUL Spread: -20.5

Over/Under: 149.5

DTROIT
Betting Trends

  • Detroit Mercy’s recent ATS data is limited, but the team is listed as heavy underdogs in most contests and has struggled to keep games close, with a very negative average scoring margin of around -20 for the 2024-25 season.

DEPAUL
Betting Trends

  • DePaul’s recent ATS performance at home shows improvement in underlying metrics, though comprehensive ATS trend numbers remain unavailable; the Blue Demons are in their second year of coach Chris Holtmann’s tenure and building toward greater consistency.

MATCHUP TRENDS

  • Given that Detroit Mercy has struggled significantly in margin of defeat and DePaul is still developing but at home, value may lie in a DePaul cover or limiting the margin, rather than an upset. The margin disparity, rebounding deficits for Detroit, and DePaul’s home-court familiarity suggest this game may not offer large upside for the Titans in ATS terms, but Detroit Mercy’s status as underdog and their potential to crash the glass aggressively could provide some intrigue if they execute.

DTROIT vs. DEPAUL
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: REMI'S STILL ANALYZING MARKETS

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Detroit Mercy vs DePaul Prediction & Odds:
Free CBB Betting Insights for 11/23/25

The November 23 matchup between the Detroit Mercy Titans and the DePaul Blue Demons brings together two programs at very different stages of development, creating a contrast that shapes expectations while still leaving room for volatility if the underdog can dictate effort-based margins. DePaul enters this game at home with the advantage of stability, a more complete roster, and a clearer identity under its current coaching direction, giving the Blue Demons the tools to impose structure, control possessions, and keep Detroit Mercy from finding rhythm or confidence. Their goal will be to set a deliberate tempo by executing early-clock actions with precision, establishing interior scoring touches, and using purposeful ball movement to stretch Detroit Mercy’s defense into rotations that fatigue and expose weaknesses. Rebounding becomes an immediate priority for DePaul, as winning the glass not only eliminates Detroit Mercy’s second-chance scoring but also restricts the Titans from slowing the game and extending possessions in ways that could offset talent gaps. Defensively, DePaul must stay compact, protect the paint, and avoid overextending on closeouts, instead forcing Detroit Mercy to generate their points through contested shots and late-clock improvisation. On the other side, Detroit Mercy approaches this game with a blueprint built entirely around effort, rebounding commitment, and playing with urgency to manufacture competitiveness against a more structurally refined opponent. Their clearest path involves pushing pace whenever possible, attacking early out of transition, and crashing the offensive glass to secure second-chance looks that can keep possessions alive and disrupt DePaul’s flow.

For Detroit Mercy, defensive discipline is essential—sprinting back on misses, communicating through screens, and executing rotations without hesitation to prevent DePaul from stringing together rhythm-based scoring runs that widen the margin. If the Titans allow DePaul to settle into organized half-court offense, the matchup tilts heavily against them; therefore, they must inject energy into the game by winning hustle battles, forcing loose-ball scrums, and creating opportunistic fast-break chances that destabilize the home team. Bench production also plays a pivotal role for both sides. DePaul’s depth must maintain pressure, continue rebounding control, and avoid the lapses that have often plagued teams favored at home, while Detroit Mercy’s reserves must bring relentless activity and defensive engagement to keep the contest from slipping during rotation sequences. Emotionally, DePaul must guard against complacency, treating this matchup as an opportunity to reinforce consistency rather than assuming superiority will carry them. Detroit Mercy must embrace the role of challenger, playing with freedom, aggression, and the determination to remain within striking distance rather than allowing early deficits to dictate outcome. Ultimately, the game’s decisive factor lies in the possession battle: if DePaul controls rebounds, limits turnovers, and executes their structured offense, they are positioned to dominate; if Detroit Mercy wins effort categories, creates second-chance scoring, and disrupts pace, they can make the contest far tighter than projections indicate.

Get live CBB odds and precise AI CBB picks, predictions, and cover probabilities.

Detroit Mercy Titans CBB Preview

Detroit Mercy enters its November 23 road matchup against DePaul with a clear understanding that the only way to stay competitive is by embracing an effort-driven, high-energy approach built on rebounding urgency, transition opportunism, and possession scrappiness rather than relying on pure half-court execution. The Titans must attack this game with the mindset of manufacturing advantages where talent gaps exist, beginning with a commitment to crashing the offensive glass to create second-chance scoring opportunities that extend possessions, slow DePaul’s offensive rhythm, and generate momentum through sheer activity. Their offense must be built on decisiveness—pushing in transition whenever possible, attacking early in possessions before DePaul’s defense can fully organize, and seeking high-percentage finishes rather than settling for contested jumpers. Detroit Mercy’s guards must be aggressive probing the lane, drawing help defenders, and using those interior touches to create kick-outs or dump-offs that can lead to more efficient scoring. Shot selection must remain disciplined, as long rebounds off deep, hurried attempts will almost certainly feed DePaul’s transition attack. Defensively, Detroit Mercy must display connectivity and hustle across all five positions—collapsing on drives, contesting without fouling, and rotating as a unit to prevent DePaul from exploiting mismatches or rhythm-based actions. Their ability to sprint back on defense becomes essential; the Titans cannot allow DePaul to generate easy points before the defense is set, or the game risks slipping out of reach early.

Detroit Mercy must also protect the defensive glass with collective effort, as surrendering offensive rebounds to DePaul would not only lead to second-chance points but also place the Titans in a constant state of defensive retreat. Bench contributions will matter significantly; Detroit Mercy’s second unit must provide energy, defensive activity, and rebounding support rather than allowing DePaul to extend leads during rotation minutes. Emotionally, the Titans must embrace their underdog status by playing loose, aggressive, and unafraid of mistakes, channeling their freedom into effort plays rather than rushed or panicked possessions. Staying within striking distance requires patience and composure—weathering DePaul’s scoring runs, avoiding turnovers that ignite the home crowd, and responding through controlled pace rather than hurried sequences. If Detroit Mercy can win hustle categories, generate second-chance points, protect against transition breakdowns, and maintain defensive discipline, they can make this matchup more competitive than the projections imply. But if they lose the rebounding battle, allow DePaul to dictate pace, or let early deficits force them into desperation mode, the game becomes significantly more difficult. Their path to competitiveness lies entirely in effort, rebounding, and the willingness to disrupt DePaul’s structure through intensity and opportunistic play.

The Detroit Mercy Titans travel to face the DePaul Blue Demons on November 23, 2025, in a matchup that pits Detroit Mercy’s rebuilding roster and youth against DePaul’s effort to solidify progress under a newer coaching regime. With DePaul at home and seeking to enforce structure, and Detroit Mercy arriving with few expectations but the potential to disrupt, this game may turn on rebounding battles, transition defense, and which team best manages its energy across the full 40 minutes. Detroit Mercy vs DePaul AI Prediction: Free CBB Betting Insights for Nov 23. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

DePaul Blue Demons CBB Preview

DePaul enters its November 23 home matchup against Detroit Mercy with a clear opportunity to reinforce its identity, assert its structural advantages, and demonstrate the program’s ongoing growth by dictating pace, controlling the glass, and limiting the types of chaotic sequences that allow underdogs to linger. The Blue Demons must begin by establishing offensive rhythm built on strong ball movement, purposeful interior touches, and decisive execution in early-clock actions designed to force Detroit Mercy’s defense into rotations rather than allowing them to sit comfortably in set positions. Playing at home gives DePaul the luxury of leaning into its preferred pace—measured, disciplined, and possession-focused—rather than engaging in a track meet that might benefit Detroit Mercy’s effort-based style. To maintain this control, DePaul must treat every rebound as a foundational possession, especially defensive boards, which not only erase the Titans’ hopes of generating second-chance points but also enable the Blue Demons to initiate clean offensive sets without scrambling. The importance of winning the rebounding battle cannot be overstated; Detroit Mercy has historically struggled with margin deficits, but they often remain competitive for stretches when able to crash the offensive glass and force opponents into extended possessions. DePaul must counteract that by boxing out consistently, committing to five-man rebounding, and eliminating the Titans’ attempts to create momentum through extra-effort plays. Offensively, the Blue Demons should attack the paint with confidence—using ball screens, post entries, and strong drives to collapse the defense before kicking out to open shooters who can punish Detroit Mercy’s tendency to overhelp.

In doing so, DePaul forces the Titans into rotational decisions they have often struggled to navigate, creating scoring windows through both movement and patience rather than forcing contested attempts. Defensively, DePaul must remain composed and balanced, protecting the paint with layered coverage rather than overcommitting to pressure that could create driving lanes for Detroit Mercy’s guards. The Blue Demons need to focus on transition discipline; even one or two careless possessions that lead to fast-break points can give an underdog the emotional lift needed to stay competitive far longer than expected. Preventing such situations requires sprinting back on every miss, communicating early, and eliminating mismatches before Detroit Mercy can exploit them. Depth also plays an essential role, as DePaul’s second unit must maintain defensive cohesion, offensive spacing, and rebounding standards without allowing Detroit Mercy’s bench to create unexpected scoring bursts or energy shifts. Emotionally, the Blue Demons must guard against complacency—home games against rebuilding opponents are dangerous only when the favored team assumes the result instead of earning it through attention to detail. By emphasizing discipline, valuing each possession, and refusing to let Detroit Mercy generate confidence through hustle categories, DePaul can ensure that the matchup unfolds on its terms. If the Blue Demons dominate the glass, avoid turnovers, maintain offensive structure, and defend transitions with commitment, they should be positioned to control this game from the opening tip to the final buzzer, reinforcing their upward trajectory and strengthening their foundation as the season progresses.

Detroit Mercy vs DePaul Prop Picks (AI)

Remi is pouring through mountains of datapoints on each player. In fact, anytime the Titans and Blue Demons play there’s always several intriguing observations to key in on. Not to mention games played at Wintrust Arena in Nov rarely follow normal, predictable betting trends.

Remi's searched hard and found the best prop for this matchup: REMI'S STILL ANALYZING MARKETS

Detroit Mercy vs DePaul Prediction (AI)

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Remi, our AI sports wizard, has been pouring over mountains of data from every facet between the Titans and Blue Demons and using recursive machine learning and kick-ass AI to boil down the data to a single cover probability.

Interestingly enough, the data has been most fixated on the unproportionally assigned factor emotional bettors tend to put on coaching factors between a Titans team going up against a possibly unhealthy Blue Demons team. In reality, the true game analytics might reflect a moderate lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CBB AI picks for FREE now.

Below is our current AI Detroit Mercy vs DePaul picks, computer picks Titans vs Blue Demons, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
CBB 12/5 BRYANT@BROWN UNLOCK THIS PICK 5 EXECUTIVE Locked EXECUTIVE
CBB 12/5 QUINN@IONA GET FREE PICK NOW 1
CBB 12/5 GONZAG@UK UNLOCK THIS PICK 0 INTEL Locked INTEL
CBB 12/5 USD@SJST UNLOCK THIS PICK 0 INTEL Locked INTEL

These picks update as information changes—injury reports, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CBB schedule.

Detroit Mercy Betting Trends

Detroit Mercy’s recent ATS data is limited, but the team is listed as heavy underdogs in most contests and has struggled to keep games close, with a very negative average scoring margin of around -20 for the 2024-25 season.

DePaul Betting Trends

DePaul’s recent ATS performance at home shows improvement in underlying metrics, though comprehensive ATS trend numbers remain unavailable; the Blue Demons are in their second year of coach Chris Holtmann’s tenure and building toward greater consistency.

Titans vs. Blue Demons Matchup Trends

Given that Detroit Mercy has struggled significantly in margin of defeat and DePaul is still developing but at home, value may lie in a DePaul cover or limiting the margin, rather than an upset. The margin disparity, rebounding deficits for Detroit, and DePaul’s home-court familiarity suggest this game may not offer large upside for the Titans in ATS terms, but Detroit Mercy’s status as underdog and their potential to crash the glass aggressively could provide some intrigue if they execute.

Detroit Mercy vs. DePaul Game Info

November 23, 2025 • 7:00 PM EST • Wintrust Arena

Detroit Mercy vs. DePaul Odds

Remi is pouring through mountains of stats on each line. In fact, anytime the Detroit Mercy vs DePaul trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance can often follow normal, predictable patterns.

Detroit Mercy vs DePaul

Detroit Mercy vs DePaul Live Odds

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12/6/25 1PM
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West Georgia Wolves
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Presbyterian College Blue Hose
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SIU-Edwardsville Cougars
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Cleveland State Vikings
12/6/25 2PM
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Maryland Eastern Shore Hawks
American Eagles
12/6/25 2PM
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AMRCN
 
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South Carolina Gamecocks
12/6/25 2PM
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SC
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Gardner-Webb Runnin Bulldogs
12/6/25 2PM
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12/6/25 2PM
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USCUP
 
 
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Dec 6, 2025 2:00PM EST
Youngstown St Penguins
IUPUI Jaguars
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FIU Panthers
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Liberty Flames
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James Madison Dukes
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Northwestern Wildcats
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Dec 6, 2025 2:00PM EST
Delaware Blue Hens
Delaware State Hornets
12/6/25 2PM
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Dec 6, 2025 2:00PM EST
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Wisconsin Badgers
12/6/25 2PM
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Dec 6, 2025 2:00PM EST
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12/6/25 2PM
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Drexel Dragons
La Salle Explorers
12/6/25 2PM
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pk
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Princeton Tigers
Loyola Chicago Ramblers
12/6/25 2:30PM
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LOYCHI
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Dec 6, 2025 3:00PM EST
Bellarmine Knights
Murray State Racers
12/6/25 3PM
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MURRAY
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Dec 6, 2025 3:00PM EST
Idaho Vandals
South Dakota State Jackrabbits
12/6/25 3PM
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SDAKST
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Dec 6, 2025 3:00PM EST
Toledo Rockets
Oakland Golden Grizzlies
12/6/25 3PM
TOLEDO
OAKLND
+130
-160
+4 (-105)
-4 (-115)
O 164.5 (-110)
U 164.5 (-110)
Dec 6, 2025 3:00PM EST
George Mason Patriots
Virginia Tech Hokies
12/6/25 3PM
GMASON
VATECH
+160
-190
+3.5 (-110)
-3.5 (-110)
O 144 (-110)
U 144 (-110)
Dec 6, 2025 3:00PM EST
Missouri State Bears
Tulsa Golden Hurricane
12/6/25 3PM
MIZZST
TULSA
 
-800
 
-11.5 (-115)
O 138.5 (-110)
U 138.5 (-110)
Dec 6, 2025 4:00PM EST
Elon Phoenix
Wofford Terriers
12/6/25 4PM
ELON
WOFF
+150
-180
+4 (-105)
-4 (-115)
O 159.5 (-102)
U 159.5 (-118)
Dec 6, 2025 4:00PM EST
Seton Hall Pirates
Kansas State Wildcats
12/6/25 4PM
SETON
KSTATE
+145
 
+3 (-105)
 
O 147.5 (-105)
U 147.5 (-115)

CBB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Detroit Mercy Titans vs. DePaul Blue Demons on November 23, 2025 at Wintrust Arena.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CBB odds pages, and compare prices before you place a bet.

LEAN %WIN UNITS RESULT
UTAHST@SFLA SFLA +1.5 54.0% 3 WIN
EWASH@DENVER DENVER -130 58.4% 4 WIN
LVILLE@ARK LVILLE -2 53.8% 3 LOSS
BALLST@EVAN BALLST +6.5 55.6% 5 LOSS
NWEST@WISC NWEST +10.5 57.0% 6 LOSS
SOBAMA@NMEXST NMEXST +2.5 56.3% 6 WIN
VATECH@SC SC -118 54.7% 4 LOSS
OKLA@WAKE WAKE -4 56.0% 6 LOSS
UNC@UK UNC +6.5 53.5% 2 WIN
GEORGIA@FSU GEORGIA +1.5 54.8% 5 WIN
TENN@CUSE CUSE +7.5 53.3% 3 WIN
UAB@MTSU UAB -125 56.7% 4 LOSS
PORT@STNFRD PORT +18.5 54.9% 4 LOSS
NH@FAIR NH +11 55.0% 5 WIN
UCSB@LEHIGH LEHIGH +10.5 54.9% 4 WIN
BYU@DAYTON DAYTON +10.5 55.1% 5 WIN
WKY@WICHST WKY +6.5 55.4% 5 WIN
WISC@TCU TCU +6.5 54.3% 4 WIN
GTOWN@DAYTON GTOWN +1.5 56.4% 6 LOSS
STLOU@SNCLRA STLOU -125 57.5% 4 WIN
TCU@FLA TCU +12 54.7% 4 WIN
UNLV@RUT RUT +4.5 55.0% 5 WIN
WKY@SFLA WKY +8.5 56.1% 7 WIN
NOCOLO@AF NOCOLO -4.5 54.8% 4 WIN
HARV@BC HARV +7.5 53.8% 3 LOSS
COLOST@VATECH UNDER 155.5 56.7% 6 WIN
OLEMISS@IOWA IOWA -125 61.3% 6 WIN
HOU@TENN HOU -2.5 54.5% 4 LOSS
UCSD@BRAD UCSD -110 54.5% 4 WIN
MICH@AUBURN MICH -4.5 53.4% 2 WIN
MTSU@MCNSE MTSU +7.5 56.5% 6 LOSS
LAMAR@MONTANA LAMAR +6.5 55.9% 5 WIN
NWEST@SC SC +6.5 57.5% 6 WIN
SANFRAN@MINN SANFRAN -115 56.9% 6 WIN
ARKLR@TEXST TEXST -6.5 56.9% 6 WIN
GEORGIA@XAVIER XAVIER +10.5 53.1% 2 WIN
MORGAN@OLDDOM MORGAN +14.5 55.1% 5 LOSS
NEWORL@FRESNO NEWORL +7 53.4% 3 LOSS
ARMY@MARIST ARMY +14 55.5% 5 WIN
MISSST@KSTATE MISSST -130 58.6% 5 LOSS
MAINE@MERMAK MERMAK -6.5 56.2% 6 WIN
ARIZ@UCONN ARIZ +6.5 53.3% 2 WIN
BAMA@ILL ILL -2.5 53.5% 2 LOSS
SFLA@OKLAST OKLAST -4 54.0% 2 WIN
ABIL@TEXST TEXST -125 58.0% 6 WIN
VERMONT@BUFF VERMONT -2.5 55.3% 5 LOSS
RADFRD@SC SC -9.5 57.2% 7 WIN
MICHST@UK MICHST +5.5 54.1% 4 WIN
GRAMB@USD GRAMB +6.5 56.4% 6 LOSS
SOILL@NDAKST NDAKST +1.5 56.1% 6 WIN
TROY@CSUN CSUN +5.5 54.5% 4 WIN