Wildcats vs. Blue Devils
Prediction, Odds & Props
Mar 27 | CBB AI Picks

Updated: 2025-03-25T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

The Sweet 16 matchup between the Arizona Wildcats and the Duke Blue Devils is scheduled for March 27, 2025, at the Prudential Center in Newark, New Jersey. This game features a rematch from earlier in the season, where Duke secured a 69-55 victory over Arizona.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Mar 27, 2025

Start Time: 9:39 PM EST​

Venue: Prudential Center​

Blue Devils Record: (33-3)

Wildcats Record: (24-12)

OPENING ODDS

ARIZ Moneyline: +327

DUKE Moneyline: -426

ARIZ Spread: +8.5

DUKE Spread: -8.5

Over/Under: 154

ARIZ
Betting Trends

  • Arizona has a 22-14-0 record against the spread (ATS) this season. As underdogs of 1.5 points or more, they have an ATS record of 20-14.

DUKE
Betting Trends

  • Duke has covered the spread in 21 of 35 games this season. As favorites of 1.5 points or more, their ATS record includes covering in one of three such contests.

MATCHUP TRENDS

  • Historically, Arizona has performed well as an underdog in the NCAA Tournament, with a 12-5 ATS record since 1996, winning seven of those games outright.

ARIZ vs. DUKE
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: C. Flagg under 20.5 Points

LIVE CBB ODDS

CBB ODDS COMPARISON

WANT MORE AI PICKS?

VAULT
VS. SPREAD
308-221
VAULT
NET UNITS
(INCL VIG)
+418
VAULT
NET PROFIT
(INCL VIG)
$100/UNIT
$41,803
EXECUTIVE
VS. SPREAD
1554-1329
EXECUTIVE
NET UNITS
(INCL VIG)
+376.6
EXECUTIVE
NET PROFIT
(INCL VIG)
$100/UNIT
$37,661

AI SPORTS PICK PRODUCTS

Create a Free Account

‘Create an Account’ to Get Remi’s Picks Today.

Remi Finds New Picks

Remi calculates the probability a team will cover the line.

Remi Works 24/7

Remi uses this probability to assign units to each pick.

Get Remi's AI Picks

Get Remi’s Top AI Sports Picks sent direct to your inbox.

Arizona vs Duke Prediction & Odds:
Free CBB Betting Insights for 3/27/25

The upcoming Sweet 16 clash between the Arizona Wildcats and the Duke Blue Devils is set to be a compelling encounter, showcasing two storied programs with rich histories in NCAA basketball. Arizona, seeded fourth with a 24-12 record, enters this game as a 9.5-point underdog against top-seeded Duke, which boasts a 33-3 record. The Wildcats have demonstrated resilience throughout the season, overcoming challenges and displaying a balanced offensive and defensive approach. Their journey to the Sweet 16 included a notable comeback victory over Oregon, where they rallied from a 15-point deficit to win 87-83. This resilience will be crucial as they face a formidable Duke team that has been dominant on both ends of the court. Duke’s success this season can be attributed to their strong defensive performances and efficient scoring. In their previous meeting with Arizona earlier in the season, the Blue Devils secured a 69-55 victory, showcasing their ability to limit the Wildcats’ offensive opportunities. This defensive prowess has been a hallmark of Duke’s play, allowing them to control the tempo and dictate the flow of the game. Offensively, Duke has a balanced attack, with multiple players capable of contributing significant points, making them a challenging opponent to defend against. Betting lines for this matchup favor Duke by 9.5 points, with a total over/under set at 154.5 points. Arizona’s ATS record stands at 22-14-0, while Duke has covered the spread in 21 of 35 games this season. Historically, Arizona has performed well as an underdog in the NCAA Tournament, with a 12-5 ATS record since 1996, winning seven of those games outright.

This suggests that while Duke is favored, Arizona has a history of exceeding expectations in similar situations. The key to this game will likely be Arizona’s ability to adapt and counter Duke’s defensive strategies. In their previous encounter, the Wildcats struggled offensively, scoring only 55 points. To improve upon this performance, Arizona will need to enhance their offensive execution, focusing on ball movement and creating high-quality scoring opportunities. Additionally, limiting turnovers and controlling the pace of the game will be essential to prevent Duke from establishing their preferred rhythm. Conversely, Duke will aim to replicate their earlier success by maintaining defensive intensity and capitalizing on Arizona’s weaknesses. By applying pressure and forcing the Wildcats into difficult situations, the Blue Devils can create transition opportunities and build momentum. Their balanced scoring attack will also be crucial in keeping Arizona’s defense off balance and preventing them from keying in on specific players. This Sweet 16 matchup promises to be a thrilling contest between two teams with contrasting styles and strengths. While Duke enters as the favorite, Arizona’s history of resilience and success as an underdog adds an intriguing layer to the narrative. Fans can anticipate a hard-fought game with strategic adjustments and competitive play as both teams vie for a coveted spot in the Elite Eight.

Arizona Wildcats CBB Preview

The Arizona Wildcats arrive at the Sweet 16 with a 24-12 overall record and a clear underdog label heading into their clash with the top-seeded Duke Blue Devils, but their path to this stage has showcased their capacity for grit, adaptation, and clutch performances in high-pressure scenarios, especially their memorable 87-83 comeback win against Oregon in the Round of 32 after trailing by as much as 15 points—a game that underscored both their mental toughness and offensive explosiveness under head coach Tommy Lloyd. Arizona’s offensive system is defined by balance, tempo, and ball-sharing, averaging just under 81 points per game, with four players scoring in double figures, headlined by guard Kylan Boswell, who facilitates the offense with poise and leads the team in assists while maintaining solid efficiency from beyond the arc, and forward Motiejus Krivas, whose emergence in the post has added depth and consistency to Arizona’s inside-out game. What makes Arizona dangerous is their ability to space the floor, move without the ball, and generate clean looks through constant off-ball motion and high pick-and-roll sets that open up lanes for shooters like Pelle Larsson, who brings both perimeter scoring and veteran experience to anchor the team’s backcourt, while KJ Lewis has developed into a reliable two-way presence, capable of guarding opposing scorers and knocking down timely shots.

On defense, Arizona’s 1-2-2 pressure and help-heavy rotations have been effective at forcing contested mid-range shots and denying open three-point attempts, contributing to a respectable 69.8 points allowed per game; however, their biggest concern remains defending elite perimeter playmakers like Duke’s Jeremy Roach and Cooper Flagg, especially in transition, where Arizona has shown occasional lapses in getting back and protecting the rim against athletic finishers. Rebounding has been a strength, with Arizona averaging nearly 40 boards per game and frequently dominating second-chance opportunities—an area that could be pivotal against Duke’s elite frontcourt. Statistically, Arizona has been solid against the spread (ATS), posting a 22-14 record overall, and historically they’ve embraced the underdog role well, going 12-5 ATS in tournament games as underdogs since 1996 and winning outright in seven of those; their confidence in tight, high-stakes moments should not be underestimated. Turnovers will be key—the Wildcats average 12.5 per game, and reducing those mistakes will be essential to avoid fueling Duke’s transition game. Arizona will also look to control pace, slow down Duke’s early scoring bursts, and stretch possessions late in the shot clock to disrupt the rhythm and flow that Duke thrives on. If the Wildcats can hit their threes at a 38% clip like they have in their recent wins, crash the boards with their usual ferocity, and get meaningful contributions from their bench, they are fully capable of keeping this game close and potentially pulling off an upset. This game will demand Arizona’s most complete effort of the season, blending defensive discipline with offensive creativity, and if their veterans step up while their younger players remain poised under pressure, Arizona’s underdog spirit might just carry them into the Elite Eight.

The Sweet 16 matchup between the Arizona Wildcats and the Duke Blue Devils is scheduled for March 27, 2025, at the Prudential Center in Newark, New Jersey. This game features a rematch from earlier in the season, where Duke secured a 69-55 victory over Arizona. Arizona vs Duke AI Prediction: Free CBB Betting Insights for Mar 27. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Duke Blue Devils CBB Preview

The Duke Blue Devils, boasting a 33-3 record, have demonstrated exceptional performance throughout the season, solidifying their position as a top seed in the NCAA Tournament. Under the leadership of Coach Jon Scheyer, Duke has maintained a balanced approach, excelling in both offensive and defensive facets of the game. Their defensive prowess has been particularly noteworthy, consistently limiting opponents’ scoring opportunities and controlling the tempo of games. This defensive strength was evident in their earlier season victory over Arizona, where they held the Wildcats to just 55 points. Offensively, the Blue Devils employ a multifaceted attack, with contributions from a deep roster. Freshman standout Cooper Flagg has been a significant addition, leading the team with 24 points in the previous matchup against Arizona. Flagg’s versatility and scoring ability have provided Duke with a reliable offensive option, complementing the experience and leadership of senior guard Jeremy Roach. Roach’s court vision and playmaking skills have been instrumental in orchestrating the Blue Devils’ offense, ensuring efficient ball movement and high-percentage shot opportunities. Duke’s success is also attributed to their depth, with players like Caleb Foster and Kob Knueppel making significant contributions off the bench. This depth allows Coach Scheyer to implement various lineups and strategies, adapting to different opponents and maintaining a high level of intensity throughout games. Duke’s bench has consistently outperformed opposing second units, often creating crucial momentum swings during key stretches of play. That roster depth also allows them to maintain defensive pressure across 40 minutes without sacrificing offensive production. The Blue Devils excel at switching defensive schemes mid-game, whether applying full-court pressure, trapping high ball screens, or collapsing into a zone to protect against inside penetration—all of which have made them a top-15 team in adjusted defensive efficiency this season.

Their frontcourt, anchored by Kyle Filipowski, provides a physical and skilled presence on both ends of the floor. Filipowski, a 7-footer with soft hands and stretch range, averages nearly 15 points and 8 rebounds per game, forcing opposing bigs to guard outside their comfort zone while protecting the rim on the other end. In tandem with Flagg, the two form one of the most dynamic forward pairings in the country, capable of switching onto smaller guards and still dominating the boards. Duke’s offensive tempo is balanced; they don’t always push in transition but are lethal when opportunities present themselves—especially off turnovers, where Roach and Flagg excel at converting fast breaks. Their half-court offense is structured around precision ball movement and unselfish play, as they average over 16 assists per game, reflecting a team-first mentality that has made them difficult to defend. From beyond the arc, the Blue Devils shoot at an efficient 37%, and when they catch fire from deep, their opponents often struggle to keep pace. In late-game situations, Duke is reliable from the free-throw line, shooting over 76% as a team and rarely giving away possessions in crunch time. One of the most impressive qualities of this squad is their ability to remain composed under pressure, a testament to both their veteran leadership and elite coaching. Entering this Sweet 16 matchup against Arizona, Duke will aim to replicate the formula that earned them a decisive win earlier in the season: suffocating defense, a patient and deadly offense, and leveraging their size and depth to gradually wear down the Wildcats. While Arizona has proven capable of upsets, Duke’s consistency, combined with the ability to dominate both in the paint and from the perimeter, gives them a clear path to the Elite Eight—provided they execute their game plan with the discipline and intensity they’ve shown all season. With one of the best scoring margins in the nation and a defense that can adapt to any tempo, the Blue Devils will look to assert their authority early, force Arizona into uncomfortable shot selections, and let their stars take over as the game progresses. In a high-stakes contest like this, Duke’s combination of experience, talent, and coaching acumen gives them every reason to be confident in advancing another step toward a Final Four appearance.

Arizona vs. Duke Prop Picks (AI)

Remi is pouring through loads of stats on each line. In fact, anytime the Wildcats and Blue Devils play there’s always several intriguing trends to key in on. Not to mention games played at Prudential Center in Mar can often follow normal, predictable betting trends.
Remi's searched hard and found the best prop for this matchup: C. Flagg under 20.5 Points

Arizona vs. Duke Prediction (AI)

Remi Robot Icon

Remi, our AI sports wizard, has been pouring over mountains of data from every simulation between the Wildcats and Blue Devils and using recursive machine learning and industry leading AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most keyed in on the unproportionally assigned weight emotional bettors regularly put on player performance factors between a Wildcats team going up against a possibly improved Blue Devils team. It appears the true game analytics appear to reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CBB AI picks for FREE now.

Below is our current AI Arizona vs Duke picks, computer picks Wildcats vs Blue Devils, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
ACTIVE PICKS LOCKED - SEE NOW

These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CBB schedule.

Wildcats Betting Trends

Arizona has a 22-14-0 record against the spread (ATS) this season. As underdogs of 1.5 points or more, they have an ATS record of 20-14.

Blue Devils Betting Trends

Duke has covered the spread in 21 of 35 games this season. As favorites of 1.5 points or more, their ATS record includes covering in one of three such contests.

Wildcats vs. Blue Devils Matchup Trends

Historically, Arizona has performed well as an underdog in the NCAA Tournament, with a 12-5 ATS record since 1996, winning seven of those games outright.

Arizona vs. Duke Game Info

Arizona vs Duke starts on March 27, 2025 at 9:39 PM EST.

Venue: Prudential Center.

Spread: Duke -8.5
Moneyline: Arizona +327, Duke -426
Over/Under: 154

Arizona: (24-12)  |  Duke: (33-3)

Remi's searched hard and found the best prop for this matchup: C. Flagg under 20.5 Points. Prices move—always shop for the best number.

Historically, Arizona has performed well as an underdog in the NCAA Tournament, with a 12-5 ATS record since 1996, winning seven of those games outright.

ARIZ trend: Arizona has a 22-14-0 record against the spread (ATS) this season. As underdogs of 1.5 points or more, they have an ATS record of 20-14.

DUKE trend: Duke has covered the spread in 21 of 35 games this season. As favorites of 1.5 points or more, their ATS record includes covering in one of three such contests.

See our latest CBB picks and odds pages for 2025 to compare prices before you bet.

Arizona vs. Duke Odds

AI algorithm Remi is pouring through tons of data points on each player. In fact, anytime the Arizona vs Duke trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.

Arizona vs Duke Opening Odds

ARIZ Moneyline: +327
DUKE Moneyline: -426
ARIZ Spread: +8.5
DUKE Spread: -8.5
Over/Under: 154

Arizona vs Duke Live Odds

Games PTS ML SPR O/U

CBB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Arizona Wildcats vs. Duke Blue Devils on March 27, 2025 at Prudential Center.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CBB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
DRAKE@MIZZOU DRAKE +6.5 53.50% 2 WIN
XAVIER@TEXAS XAVIER -2.5 53.40% 2 WIN
UAB@MEMP MEMP -3.5 54.00% 2 WIN
LVILLE@DUKE LVILLE +6.5 53.10% 2 LOSS
ECU@UAB UAB -5 53.60% 2 WIN
PURDUE@MICH MICH +3 54.60% 3 WIN
CLEM@LVILLE CLEM -120 56.10% 3 LOSS
COL@HOU ANDREJ JAKIMOVSKI PTS + REB + AST - UNDER 15.5 53.70% 2 LOSS
FORD@GWASH FORD +7 53.80% 2 WIN
SEATTLE@ABIL ABIL +6 54.50% 3 WIN
BAMAST@TEXSOU BAMAST -110 55.40% 4 WIN
OHIO@TOLEDO TOLEDO +3 56.70% 4 WIN
UVA@GATECH GATECH +1.5 53.70% 2 WIN
COLO@WVU COLO +7.5 53.20% 2 WIN
USC@RUT USC -115 54.00% 2 WIN
TEXAS@VANDY VANDY -130 56.50% 3 LOSS
BUTLER@PROV BUTLER -115 55.20% 3 WIN
IDAHO@MONTANA MONTANA -6 53.50% 2 WIN
TROY@JMAD TROY -125 55.60% 2 WIN
BELMONT@DRAKE DRAKE -7.5 53.50% 2 LOSS
UCSD@UCDAV UCSD -12.5 53.40% 2 LOSS
SIUE@SEMO SEMO -2.5 54.80% 3 LOSS
ALCORN@ARKPB ARKPB +6.5 56.00% 4 WIN
NORFLK@HOWARD HOWARD +5.5 53.70% 2 LOSS
NKY@CLEVST NKY +4.5 54.40% 3 LOSS
STNFRD@ND STNFRD -125 56.40% 3 LOSS
TENN@OLEMISS OLEMISS +2.5 54.30% 3 WIN
LSALLE@GMASON GMASON -12 54.30% 3 LOSS
PITT@NCST NCST +2.5 56.70% 4 WIN
IND@OREG OREG -6.5 53.60% 2 WIN
FSU@UVA UVA -4 54.40% 3 LOSS
ARK@VANDY ARK +7.5 54.40% 3 WIN
SDGST@UNLV UNLV +2.5 54.10% 3 WIN
EKTY@JVILLE JVILLE -135 58.90% 3 WIN
MANHAT@NIAGARA MANHAT -115 54.70% 3 WIN
MEMP@UAB MEMP -115 54.90% 3 WIN
ILL@MICH MICH -2.5 56.00% 4 LOSS
OKLA@OLEMISS OKLA +7.5 54.50% 3 WIN
ARIZST@UTAH ARIZST +8.5 54.60% 3 LOSS
GC@SEATTLE GC -110 55.00% 3 WIN
PENN@CLMBIA CLMBIA -122 57.50% 4 LOSS
IONA@NIAGARA NIAGARA +1.5 54.30% 3 LOSS
MARIST@SACHRT SACHRT -120 55.40% 3 WIN
CLEVST@WRIGHT CLEVST +1.5 54.30% 3 LOSS
NDAK@STTHOM STTHOM -10 54.30% 3 WIN
USD@WASHST WASHST -12.5 55.20% 4 LOSS
CSBAK@LBEACH CSBAK -130 59.70% 4 WIN
BU@LEHIGH LEHIGH -135 57.70% 3 LOSS
DUQ@LSALLE DUQ -125 56.70% 3 WIN
BYU@ARIZST ARIZST +7.5 54.60% 3 LOSS
UTAHST@BOISE BOISE -4 55.50% 4 WIN