Bluejays vs. Tigers
Prediction, Odds & Props
Mar 22 | CBB AI Picks

Updated: 2025-03-20T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On March 22, 2025, the No. 9 seed Creighton Bluejays (25-10) will face the No. 1 seed Auburn Tigers (29-5) in the second round of the NCAA Tournament. Auburn enters the game as an 8.5-point favorite, with the over/under set at 150.5 points.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Mar 22, 2025

Start Time: 7:10 PM EST​

Venue: Rupp Arena at Central Bank Center​

Tigers Record: (29-5)

Bluejays Record: (25-10)

OPENING ODDS

CREIGH Moneyline: +343

AUBURN Moneyline: -452

CREIGH Spread: +9.5

AUBURN Spread: -9.5

Over/Under: 151.5

CREIGH
Betting Trends

  • Creighton has been strong against the spread (ATS) recently, boasting a 13-6-1 ATS record in their last 20 games.

AUBURN
Betting Trends

  • Auburn has demonstrated consistent performance, holding a 16-4 record against Southeastern Conference (SEC) opponents and a 13-1 record in non-conference play.

MATCHUP TRENDS

  • Creighton has covered the spread in six consecutive road games, indicating their resilience in away matchups.

CREIGH vs. AUBURN
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: J. Broome under 20.5 Points

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Creighton vs Auburn Prediction & Odds:
Free CBB Betting Insights for 3/22/25

The upcoming NCAA Tournament second-round matchup between the No. 9 seed Creighton Bluejays and the No. 1 seed Auburn Tigers on March 22, 2025, promises to be a thrilling contest between two formidable teams. Creighton enters the game with a 25-10 record, having secured a decisive 89-75 victory over Louisville in the first round, highlighted by guard Jamiya Neal’s standout performance of 29 points, 12 rebounds, and six assists. Auburn, boasting a 29-5 record, advanced after an 83-63 win against Alabama State, although the game was closer than the final score suggests, with Auburn leading by just one point late in the first half before pulling away. A key storyline in this matchup is the battle of the big men: Auburn’s Johni Broome, a Naismith Player of the Year contender, versus Creighton’s Ryan Kalkbrenner. Broome has been instrumental in Auburn’s success, providing dominance in the paint on both ends of the floor. Kalkbrenner, known for his defensive prowess and shot-blocking ability, will be tasked with containing Broome, making this an intriguing individual matchup that could significantly influence the game’s outcome. From a betting perspective, Auburn is favored by 8.5 points, with the over/under set at 150.5 points. Creighton has been strong against the spread recently, boasting a 13-6-1 ATS record in their last 20 games, including covering the spread in six consecutive road games.

Auburn, on the other hand, has demonstrated consistent performance, holding a 16-4 record against SEC opponents and a 13-1 record in non-conference play. Both teams exhibit contrasting styles of play. Auburn averages 83.8 points per game, 14.1 more than the 69.7 points Creighton typically allows, indicating a high-octane offense. Creighton, however, has been effective in limiting opponents’ shooting, with teams averaging just 40.8% from the field against them. This clash between Auburn’s potent offense and Creighton’s stout defense will be a focal point in determining the game’s tempo and outcome. The backcourt battle also presents intriguing matchups. Creighton’s Jamiya Neal’s recent performance showcases his ability to take over games, while Auburn’s guards have been effective in facilitating their high-scoring offense. The ability of Creighton’s guards to defend the perimeter and limit Auburn’s three-point shooting could be a determining factor in the game’s outcome. Coaching strategies will play a crucial role in this matchup. Auburn’s approach to breaking down Creighton’s defense, particularly in the half-court setting, and Creighton’s plan to counter Auburn’s transition offense will be tactical battles worth observing. Adjustments made during the game could swing momentum and ultimately decide which team advances to the Sweet 16. In summary, the Creighton vs. Auburn matchup is set to be a compelling contest featuring contrasting styles, key individual battles, and strategic coaching decisions. With Auburn’s high-powered offense clashing with Creighton’s disciplined defense, fans can anticipate an exciting game that may come down to execution in critical moments.

Creighton Bluejays CBB Preview

The Creighton Bluejays arrive at their March 22, 2025 NCAA Tournament second-round matchup against the top-seeded Auburn Tigers carrying the momentum of a confident 89–75 first-round victory over Louisville and the belief that their 25-10 record and deep, veteran-led roster make them more than capable of knocking off one of the tournament’s favorites, particularly as they lean on a combination of size, experience, perimeter shooting, and perhaps most importantly, the elite two-way play of center Ryan Kalkbrenner, who continues to anchor the Bluejays on both ends of the floor as one of the nation’s premier defensive big men and a highly efficient finisher around the rim. Creighton, coached by Greg McDermott, is no stranger to postseason success, having made a strong run to the Elite Eight in 2023, and much of that core remains intact, including guard Trey Alexander, forward Baylor Scheierman, and of course Kalkbrenner, giving them a continuity and poise that few teams can match, especially when games get tight late. In their win over Louisville, the Bluejays showcased the scoring balance that has made them dangerous all year, with Arizona State transfer Jamiya Neal exploding for 29 points while adding 12 rebounds and 6 assists in arguably the most complete individual performance of the tournament’s opening round—his emergence as an athletic wing threat has added a new layer to Creighton’s offense that already featured spacing, playmaking, and post versatility. Scheierman, one of the nation’s top rebounding guards and a knockdown three-point shooter, stretches defenses and opens up the floor, while Alexander brings a steady hand and clutch shot-making to the backcourt, and point guard Steven Ashworth provides the long-range accuracy and veteran leadership required to navigate Auburn’s disruptive perimeter defense.

Creighton’s offense is heavily predicated on spacing and decision-making, often running through high pick-and-rolls and exploiting mismatches with surgical efficiency; the Bluejays average over 16 assists per game and turn the ball over less than 10 times per contest, ranking among the best nationally in assist-to-turnover ratio, a crucial metric when facing a team like Auburn that thrives off opponent mistakes. On defense, Kalkbrenner’s presence allows Creighton to guard more aggressively on the perimeter, knowing that he can clean up breakdowns with his shot-blocking and verticality in the paint—he averages over 2.5 blocks per game and alters many more, which will be key in slowing down Johni Broome’s post scoring and Auburn’s dribble-drive offense. Creighton’s defensive rebounding has been a point of emphasis as well, as Auburn is elite at generating second-chance points, and neutralizing those opportunities will be vital to keeping the game within striking distance. The Bluejays have covered the spread in six straight road games and enter this matchup with a 13-6-1 ATS record over their last 20 contests, suggesting they consistently rise to the occasion away from home. Creighton will need to control tempo, limit transition opportunities, and stay hot from beyond the arc—where they shoot over 36% as a team—if they hope to upset the Tigers and return to the Sweet 16. With a roster built for tournament basketball, a coach who has guided this group through deep runs before, and a fearless, battle-tested core that thrives on execution and shot-making, the Bluejays represent perhaps the most dangerous lower seed left in the field, and their matchup with Auburn is shaping up to be one of the most compelling chess matches of the tournament’s second round.

On March 22, 2025, the No. 9 seed Creighton Bluejays (25-10) will face the No. 1 seed Auburn Tigers (29-5) in the second round of the NCAA Tournament. Auburn enters the game as an 8.5-point favorite, with the over/under set at 150.5 points. Creighton vs Auburn AI Prediction: Free CBB Betting Insights for Mar 22. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Auburn Tigers CBB Preview

The Auburn Tigers, holding a 29-5 record, enter their second-round NCAA Tournament game against the Creighton Bluejays as the No. 1 seed, reflecting a season marked by offensive prowess and resilience within the competitive Southeastern Conference (SEC). Under the guidance of head coach Bruce Pearl, Auburn has developed into a high-scoring unit, averaging 83.8 points per game, which is 14.1 points more than the 69.7 points per game they typically allow opponents, indicating a substantial scoring margin that has been pivotal in their success. A key contributor to this offensive efficiency is forward Johni Broome, a Naismith Player of the Year contender, whose dominance in the paint has been a cornerstone of Auburn’s game plan. Broome’s ability to score efficiently around the rim, coupled with his defensive shot-blocking presence, makes him a dual-threat that opponents must strategize against. In their first-round matchup, the Tigers secured an 83-63 victory over Alabama State; however, the game was more competitive than the final score suggests, with Auburn leading by just one point late in the first half before pulling away. This performance highlighted areas for improvement, particularly in maintaining defensive intensity throughout the game and executing in the half court under pressure, something they will need to address against a more disciplined and efficient Creighton team that won’t allow for prolonged lapses. Auburn’s offensive system thrives on tempo, floor spacing, and aggressive cuts to the basket, often creating mismatches using their athletic guards like Aden Holloway and Denver Jones, who have shown the ability to break down defenders off the dribble and knock down shots from deep. The Tigers average over 16 assists per game, ranking among the top in the nation in ball movement, a testament to their unselfishness and ability to generate open looks.

What makes Auburn particularly dangerous is their depth—Coach Bruce Pearl frequently utilizes a 9- to 10-man rotation that keeps the team fresh and able to apply defensive pressure for all 40 minutes. Defensively, Auburn forces opponents into rushed decisions, utilizing full-court pressure and aggressive hedges on ball screens to disrupt rhythm, often leading to fast-break opportunities that fuel their offense. Johni Broome anchors the paint defensively, but Auburn’s switch-heavy perimeter defense is just as vital in contesting threes and cutting off driving lanes. The Tigers are also one of the best shot-blocking teams in the nation, often dictating the pace by shutting down second-chance opportunities and igniting transition through clean rebounds and quick outlets. Their perimeter shooting, though sometimes streaky, has improved as the season has progressed, with senior guard K.D. Johnson providing veteran poise and scoring punch in critical moments. Auburn’s ability to get to the free-throw line is another weapon in its arsenal, often drawing fouls with their aggressive drives and post play; they convert at a solid clip, giving them a reliable scoring option when the pace slows down. Heading into the game against Creighton, Auburn is fully aware that they’ll be facing one of the most balanced and disciplined teams left in the tournament—a squad that doesn’t beat itself and executes on both ends. To advance, Auburn will need to impose its pace early, attack Ryan Kalkbrenner in the pick-and-roll to potentially get him into foul trouble, and maintain control of the boards, especially limiting Creighton’s second-chance looks. Their three-point defense will be tested, as Creighton is capable of shooting over 40% from deep when in rhythm, so switching and closeouts must be crisp and coordinated. Coaching will be key, and Bruce Pearl’s experience in tournament environments—paired with Auburn’s athleticism, depth, and high-octane offense—positions the Tigers as clear favorites, but they must play a complete game, limit turnovers, and avoid early foul trouble to avoid an upset. With a trip to the Sweet 16 on the line, Auburn’s blend of star power, defensive versatility, and scoring balance makes them one of the most dangerous teams in the field, and a win over Creighton would further solidify their national championship credentials as they look to build on what has already been a dominant 2024–25 campaign.

Creighton vs. Auburn Prop Picks (AI)

AI algorithm Remi is pouring through tons of stats on each line. In fact, anytime the Bluejays and Tigers play there’s always several intriguing angles to key in on. Not to mention games played at Rupp Arena at Central Bank Center in Mar rarely follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: J. Broome under 20.5 Points

Creighton vs. Auburn Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every angle between the Bluejays and Tigers and using recursive machine learning and cutting-edge AI to examine the data to a single cover probability.

Oddly enough, we’ve seen the AI has been most watching on the unproportionally assigned emphasis emotional bettors regularly put on coaching factors between a Bluejays team going up against a possibly deflated Tigers team. Trends look to say the true game analytics might reflect a slight lean against one Vegas line specifically.

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Below is our current AI Creighton vs Auburn picks, computer picks Bluejays vs Tigers, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CBB schedule.

Bluejays Betting Trends

Creighton has been strong against the spread (ATS) recently, boasting a 13-6-1 ATS record in their last 20 games.

Tigers Betting Trends

Auburn has demonstrated consistent performance, holding a 16-4 record against Southeastern Conference (SEC) opponents and a 13-1 record in non-conference play.

Bluejays vs. Tigers Matchup Trends

Creighton has covered the spread in six consecutive road games, indicating their resilience in away matchups.

Creighton vs. Auburn Game Info

Creighton vs Auburn starts on March 22, 2025 at 7:10 PM EST.

Venue: Rupp Arena at Central Bank Center.

Spread: Auburn -9.5
Moneyline: Creighton +343, Auburn -452
Over/Under: 151.5

Creighton: (25-10)  |  Auburn: (29-5)

Remi's searched hard and found the best prop for this matchup: J. Broome under 20.5 Points. Prices move—always shop for the best number.

Creighton has covered the spread in six consecutive road games, indicating their resilience in away matchups.

CREIGH trend: Creighton has been strong against the spread (ATS) recently, boasting a 13-6-1 ATS record in their last 20 games.

AUBURN trend: Auburn has demonstrated consistent performance, holding a 16-4 record against Southeastern Conference (SEC) opponents and a 13-1 record in non-conference play.

See our latest CBB picks and odds pages for 2025 to compare prices before you bet.

Creighton vs. Auburn Odds

AI algorithm Remi is pouring through loads of stats on each line. In fact, anytime the Creighton vs Auburn trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme travel distance almost always follow normal, predictable betting trends.

Creighton vs Auburn Opening Odds

CREIGH Moneyline: +343
AUBURN Moneyline: -452
CREIGH Spread: +9.5
AUBURN Spread: -9.5
Over/Under: 151.5

Creighton vs Auburn Live Odds

Games PTS ML SPR O/U

CBB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers Creighton Bluejays vs. Auburn Tigers on March 22, 2025 at Rupp Arena at Central Bank Center.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CBB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
DRAKE@MIZZOU DRAKE +6.5 53.50% 2 WIN
XAVIER@TEXAS XAVIER -2.5 53.40% 2 WIN
UAB@MEMP MEMP -3.5 54.00% 2 WIN
LVILLE@DUKE LVILLE +6.5 53.10% 2 LOSS
ECU@UAB UAB -5 53.60% 2 WIN
PURDUE@MICH MICH +3 54.60% 3 WIN
CLEM@LVILLE CLEM -120 56.10% 3 LOSS
COL@HOU ANDREJ JAKIMOVSKI PTS + REB + AST - UNDER 15.5 53.70% 2 LOSS
FORD@GWASH FORD +7 53.80% 2 WIN
SEATTLE@ABIL ABIL +6 54.50% 3 WIN
BAMAST@TEXSOU BAMAST -110 55.40% 4 WIN
OHIO@TOLEDO TOLEDO +3 56.70% 4 WIN
UVA@GATECH GATECH +1.5 53.70% 2 WIN
COLO@WVU COLO +7.5 53.20% 2 WIN
USC@RUT USC -115 54.00% 2 WIN
TEXAS@VANDY VANDY -130 56.50% 3 LOSS
BUTLER@PROV BUTLER -115 55.20% 3 WIN
IDAHO@MONTANA MONTANA -6 53.50% 2 WIN
TROY@JMAD TROY -125 55.60% 2 WIN
BELMONT@DRAKE DRAKE -7.5 53.50% 2 LOSS
UCSD@UCDAV UCSD -12.5 53.40% 2 LOSS
SIUE@SEMO SEMO -2.5 54.80% 3 LOSS
ALCORN@ARKPB ARKPB +6.5 56.00% 4 WIN
NORFLK@HOWARD HOWARD +5.5 53.70% 2 LOSS
NKY@CLEVST NKY +4.5 54.40% 3 LOSS
STNFRD@ND STNFRD -125 56.40% 3 LOSS
TENN@OLEMISS OLEMISS +2.5 54.30% 3 WIN
LSALLE@GMASON GMASON -12 54.30% 3 LOSS
PITT@NCST NCST +2.5 56.70% 4 WIN
IND@OREG OREG -6.5 53.60% 2 WIN
FSU@UVA UVA -4 54.40% 3 LOSS
ARK@VANDY ARK +7.5 54.40% 3 WIN
SDGST@UNLV UNLV +2.5 54.10% 3 WIN
EKTY@JVILLE JVILLE -135 58.90% 3 WIN
MANHAT@NIAGARA MANHAT -115 54.70% 3 WIN
MEMP@UAB MEMP -115 54.90% 3 WIN
ILL@MICH MICH -2.5 56.00% 4 LOSS
OKLA@OLEMISS OKLA +7.5 54.50% 3 WIN
ARIZST@UTAH ARIZST +8.5 54.60% 3 LOSS
GC@SEATTLE GC -110 55.00% 3 WIN
PENN@CLMBIA CLMBIA -122 57.50% 4 LOSS
IONA@NIAGARA NIAGARA +1.5 54.30% 3 LOSS
MARIST@SACHRT SACHRT -120 55.40% 3 WIN
CLEVST@WRIGHT CLEVST +1.5 54.30% 3 LOSS
NDAK@STTHOM STTHOM -10 54.30% 3 WIN
USD@WASHST WASHST -12.5 55.20% 4 LOSS
CSBAK@LBEACH CSBAK -130 59.70% 4 WIN
BU@LEHIGH LEHIGH -135 57.70% 3 LOSS
DUQ@LSALLE DUQ -125 56.70% 3 WIN
BYU@ARIZST ARIZST +7.5 54.60% 3 LOSS
UTAHST@BOISE BOISE -4 55.50% 4 WIN