N. Carolina vs Ole Miss Prediction — AI Finds CAN'T MISS CBB Lines & Props (Mar 21)

Updated: 2025-03-19T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props

On March 21, 2025, the No. 6 seed Ole Miss Rebels (22-11) will face the No. 11 seed North Carolina Tar Heels (23-13) in the first round of the NCAA Tournament at Fiserv Forum in Milwaukee. The Tar Heels are slight favorites, with a 1.5-point spread, and the over/under is set at 155.5 points.

Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.

AI Sports Betting Algorithm Remi

GAME INFO

Date: Mar 21, 2025

Start Time: 4:05 PM EST​

Venue: Fiserv Forum​

Rebels Record: (22-11)

Tar Heels Record: (23-13)

OPENING ODDS

UNC Moneyline: -134

MISS Moneyline: +112

UNC Spread: -2.5

MISS Spread: +2.5

Over/Under: 155.5

UNC
Betting Trends

  • North Carolina has a 16-20-0 record against the spread (ATS) this season, covering in 13 of 26 games when favored by 1.5 points or more.

MISS
Betting Trends

  • Ole Miss holds a 16-17-0 ATS record this season, covering in 8 of 14 games when playing as at least 1.5-point underdogs.

MATCHUP TRENDS

  • Ole Miss has been inconsistent offensively and struggles with offensive rebounds, ranking 313th nationally in offensive rebounding rate, which could impact their ability to cover the spread.

UNC vs. MISS
Best Prop Bet

  • Remi's searched hard and found the best prop for this matchup: E. Cadeau over 4.5 Assists

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N. Carolina vs Ole Miss Prediction & Odds:
Free CBB Betting Insights for 3/21/25

The NCAA Tournament first-round matchup between the No. 6 seed Ole Miss Rebels and the No. 11 seed North Carolina Tar Heels on March 21, 2025, at Fiserv Forum in Milwaukee, presents an intriguing clash of contrasting styles and narratives. North Carolina, entering with a 23-13 record, secured their spot in the Round of 64 with a dominant 95-68 victory over San Diego State in the First Four, showcasing their offensive firepower and resilience. The Tar Heels, led by senior guard RJ Davis, who averages 17 points per game, have demonstrated a propensity for high-scoring affairs, averaging 81.2 points per game, which ranks among the top offenses nationally. Their up-tempo style emphasizes quick transitions, perimeter shooting, and aggressive drives to the basket, making them a formidable challenge for any defense. Conversely, Ole Miss, with a 22-11 record, has built their success on defensive solidity and experience. Under the guidance of coach Chris Beard, the Rebels have become known for their ability to stifle opponents, allowing an average of 71.7 points per game. Their roster boasts significant senior leadership, with eight of their top nine players being seniors, including point guard Sean Pedulla, who brings previous NCAA Tournament experience from his tenure at Virginia Tech. Offensively, the Rebels average 77.2 points per game, relying on a balanced attack and strategic shot selection. A critical aspect of this matchup will be the battle of tempos; North Carolina thrives in fast-paced games, while Ole Miss prefers a more controlled, half-court approach.

The Tar Heels’ ability to dictate the speed of play could be pivotal in breaking through the Rebels’ defensive schemes. Additionally, rebounding will play a significant role; North Carolina’s athleticism and size give them an edge on the boards, whereas Ole Miss has struggled with offensive rebounding, ranking 313th nationally, which could limit their second-chance opportunities. From a betting perspective, both teams have had challenges against the spread (ATS) this season. North Carolina holds a 16-20-0 ATS record, covering in 13 of 26 games when favored by 1.5 points or more. Ole Miss has a 16-17-0 ATS record, covering in 8 of 14 games when playing as at least 1.5-point underdogs. The over/under is set at 155.5 points, reflecting expectations of a high-scoring contest, especially if North Carolina can impose their offensive rhythm. However, Ole Miss’s defensive capabilities could lead to a lower-scoring game, making the total points a compelling aspect for bettors to consider. In terms of momentum, North Carolina’s recent performance in the First Four indicates a team hitting its stride at the right time, with their offense firing on all cylinders. Ole Miss, despite a strong season, has shown vulnerabilities, particularly in high-scoring games, which could be exploited by the Tar Heels. Ultimately, this matchup may hinge on which team can assert their style of play; if North Carolina can maintain a fast pace and capitalize on transition opportunities, they stand a favorable chance. Conversely, if Ole Miss can control the tempo, limit turnovers, and exploit North Carolina’s defensive lapses, they could secure a victory. This game epitomizes the unpredictability of March Madness, where contrasting philosophies and execution under pressure will determine who advances.

N. Carolina Tar Heels CBB Preview

The North Carolina Tar Heels arrive at their March 21, 2025 NCAA Tournament first-round clash against Ole Miss as the No. 11 seed with a 23-13 record and a head of steam after a dominant First Four performance in which they dismantled San Diego State 95-68, signaling to the rest of the bracket that they’re not your typical double-digit seed but a storied program with elite firepower, a resurgent identity, and the tournament pedigree to be a serious problem for higher seeds. Head coach Hubert Davis has reignited Carolina’s classic uptempo identity, with the Tar Heels ranking among the top 20 teams in scoring at 81.2 points per game, using their length, athleticism, and transition prowess to overwhelm opponents in waves. The heartbeat of this Tar Heels team is senior guard RJ Davis, who averages 17.0 points per game and has established himself as one of the most fearless scorers in the country, capable of knocking down perimeter shots, attacking the rim, and creating off the dribble in isolation. Davis’s leadership is matched by the emergence of forward Harrison Ingram, a transfer from Stanford who has brought versatility to the frontcourt, averaging double figures while contributing significantly on the glass and defensively, helping Carolina play switchable and fast lineups that can stretch the floor on offense and recover quickly on defense. Armando Bacot continues to be a force inside, providing physicality, interior scoring, and veteran leadership in the paint, averaging a near double-double and serving as a dependable anchor who draws double teams and opens up space for shooters.

The Tar Heels’ offense is balanced and fast-paced, often fueled by their ability to rebound and immediately push the tempo in transition, where they excel at creating mismatches and getting early offense before defenses can set. Defensively, they’ve shown improvement in recent weeks, using their athleticism to apply pressure on the perimeter and disrupt opposing guards, though they’ve occasionally struggled with rotations and closing out on shooters. Against Ole Miss, their goal will be to impose their tempo, dominate the glass, and pressure the Rebels into taking tough, contested shots late in the shot clock. UNC’s 16-20 record against the spread doesn’t tell the full story of a team that struggled early but has steadily found its stride and is now playing its best basketball of the season. The key for the Tar Heels will be to stay aggressive, hit early shots to open up driving lanes, and use their depth to wear down Ole Miss over 40 minutes. Their rebounding advantage, particularly on the offensive glass, could be a game-breaking edge against a Rebels squad that ranks 313th in offensive rebounding rate and has been inconsistent in second-chance defense. If Carolina’s backcourt continues to control pace and Davis plays with the confidence he’s shown in the last several outings, they could overwhelm a methodical Ole Miss team and take command of the game early. With experience, momentum, and elite talent all converging at the right time, the Tar Heels enter this matchup not just hoping to survive, but with every intention to dictate, dismantle, and advance—exactly the way bluebloods do when March expectations meet March opportunity.

On March 21, 2025, the No. 6 seed Ole Miss Rebels (22-11) will face the No. 11 seed North Carolina Tar Heels (23-13) in the first round of the NCAA Tournament at Fiserv Forum in Milwaukee. The Tar Heels are slight favorites, with a 1.5-point spread, and the over/under is set at 155.5 points. N. Carolina vs Ole Miss AI Prediction: Free CBB Betting Insights for Mar 21. Credit USA TODAY/IMAGN

Credit: USA TODAY/IMAGN

Ole Miss Rebels CBB Preview

The Ole Miss Rebels enter the NCAA Tournament as the No. 6 seed in the South Region, boasting a 22-11 record that reflects a season marked by defensive prowess, veteran leadership, and strategic acumen under the guidance of head coach Chris Beard. This appearance marks the program’s first NCAA Tournament berth since 2019 and only the 10th in its history, signaling a significant achievement for the Rebels. A cornerstone of their success has been their defensive tenacity, with the team allowing an average of 71.7 points per game, a testament to their ability to disrupt opponents’ offensive rhythms and force contested shots. Central to this defensive identity is senior point guard Sean Pedulla, whose prior NCAA Tournament experience with Virginia Tech has been invaluable. Pedulla not only orchestrates the offense with precision but also sets the tone defensively with his on-ball pressure and leadership. The Rebels’ roster is laden with experience, featuring eight seniors among their top nine rotation players, providing a wealth of maturity and composure in high-pressure situations. Offensively, Ole Miss averages 77.2 points per game, employing a balanced attack that emphasizes ball movement and high-percentage shots. However, a notable weakness has been their offensive rebounding, with the team ranking 313th nationally in offensive rebounding rate, which has limited their second-chance scoring opportunities. This deficiency underscores the importance of efficient initial shot selection and defensive rebounding to prevent opponents from capitalizing on second-chance opportunities, especially in a matchup against a North Carolina team known for its athleticism and glass dominance. Ole Miss will need to be sharp in half-court execution, valuing each possession and minimizing empty trips if they hope to keep pace with a high-octane Tar Heels offense. While the Rebels may not have a singular dominant scorer, their offensive identity thrives on depth and distribution, with multiple players capable of stepping up in key moments. Forward Jaemyn Brakefield provides interior scoring and defensive length, while wings like Matthew Murrell and Allen Flanigan add perimeter shooting and slashing abilities that give Ole Miss balance across all three levels of the court.

The Rebels’ ability to slow the game down, defend without fouling, and avoid being baited into an up-tempo affair will be crucial if they are to neutralize North Carolina’s offensive rhythm. Coach Chris Beard, known for his methodical preparation and defensive game plans dating back to his Final Four run with Texas Tech, brings a tournament-tested philosophy that prioritizes control, toughness, and execution over flash and volume—traits that will be needed to combat the Tar Heels’ aggressive transition game. From a betting standpoint, the Rebels have been slightly below .500 against the spread (16-17), and while they’ve covered in 8 of 14 games as at least 1.5-point underdogs, their vulnerability on the glass and inconsistency in scoring stretches have contributed to some unpredictable outcomes. The key to an Ole Miss victory lies in their ability to turn the game into a grind: controlling possessions, forcing North Carolina into contested jumpers late in the clock, and winning the free throw battle. This is not a team that wants to engage in a track meet, so controlling tempo through strong guard play and defensive rebounding is essential. With Pedulla anchoring the offense and the team’s veteran-heavy rotation providing tournament maturity, the Rebels will look to draw on their collective experience to weather runs and make timely plays on both ends of the floor. While Ole Miss enters as a slight underdog, the margins are thin, and their experience, coaching pedigree, and defensive toughness make them a legitimate threat to advance past the first round if they execute their game plan and maintain composure in the face of North Carolina’s athleticism. This game is an opportunity for the Rebels to prove that their success wasn’t just a product of a strong SEC campaign but a sign of a well-rounded, dangerous team capable of making noise on the national stage. If they can rise to the occasion, play smart basketball, and capitalize on their veteran edge, Ole Miss could be poised to engineer one of the tournament’s most methodical and disciplined first-round victories.

N. Carolina vs. Ole Miss Prop Picks (AI)

Remi is pouring through loads of datapoints on each player. In fact, anytime the Tar Heels and Rebels play there’s always several intriguing trends to key in on. Not to mention games played at Fiserv Forum in Mar can often follow normal, predictable patterns.
Remi's searched hard and found the best prop for this matchup: E. Cadeau over 4.5 Assists

N. Carolina vs. Ole Miss Prediction (AI)

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Remi, our AI sports genius, has been pouring over exorbitant amounts of data from every simulation between the Tar Heels and Rebels and using recursive machine learning and industry leading AI to examine the data to a single cover probability.

The Algorithm has been most focused on the unproportionally assigned factor human bettors often put on player performance factors between a Tar Heels team going up against a possibly unhealthy Rebels team. It appears the true game analytics might reflect a slight lean against one Vegas line in particular.

Unlock this in-depth AI prediction and all of our CBB AI picks for FREE now.

Below is our current AI N. Carolina vs Ole Miss picks, computer picks Tar Heels vs Rebels, best bets, model edges, confidence ratings.

DATE GAME LEAN %WIN UNITS LEVEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CBB schedule.

Tar Heels Betting Trends

North Carolina has a 16-20-0 record against the spread (ATS) this season, covering in 13 of 26 games when favored by 1.5 points or more.

Rebels Betting Trends

Ole Miss holds a 16-17-0 ATS record this season, covering in 8 of 14 games when playing as at least 1.5-point underdogs.

Tar Heels vs. Rebels Matchup Trends

Ole Miss has been inconsistent offensively and struggles with offensive rebounds, ranking 313th nationally in offensive rebounding rate, which could impact their ability to cover the spread.

N. Carolina vs. Ole Miss Game Info

N. Carolina vs Ole Miss starts on March 21, 2025 at 4:05 PM EST.

Spread: Ole Miss +2.5
Moneyline: N. Carolina -134, Ole Miss +112
Over/Under: 155.5

N. Carolina: (23-13)  |  Ole Miss: (22-11)

Remi's searched hard and found the best prop for this matchup: E. Cadeau over 4.5 Assists. Prices move—always shop for the best number.

Ole Miss has been inconsistent offensively and struggles with offensive rebounds, ranking 313th nationally in offensive rebounding rate, which could impact their ability to cover the spread.

UNC trend: North Carolina has a 16-20-0 record against the spread (ATS) this season, covering in 13 of 26 games when favored by 1.5 points or more.

MISS trend: Ole Miss holds a 16-17-0 ATS record this season, covering in 8 of 14 games when playing as at least 1.5-point underdogs.

See our latest CBB picks and odds pages for 2025 to compare prices before you bet.

N. Carolina vs. Ole Miss Odds

Remi is pouring through tons of stats on each line. In fact, anytime the N. Carolina vs Ole Miss trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable betting trends.

N. Carolina vs Ole Miss Opening Odds

UNC Moneyline: -134
MISS Moneyline: +112
UNC Spread: -2.5
MISS Spread: +2.5
Over/Under: 155.5

N. Carolina vs Ole Miss Live Odds

Games PTS ML SPR O/U

CBB Past Picks

Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.

This preview covers N. Carolina Tar Heels vs. Ole Miss Rebels on March 21, 2025 at Fiserv Forum.
Odds shown reflect widely available numbers and may update closer to kickoff.

Want more? Check live edges, player props, and line moves on our CBB odds pages, and compare prices before you place a bet.

    LEAN     %WIN     UNITS RESULT
DRAKE@MIZZOU DRAKE +6.5 53.50% 2 WIN
XAVIER@TEXAS XAVIER -2.5 53.40% 2 WIN
UAB@MEMP MEMP -3.5 54.00% 2 WIN
LVILLE@DUKE LVILLE +6.5 53.10% 2 LOSS
ECU@UAB UAB -5 53.60% 2 WIN
PURDUE@MICH MICH +3 54.60% 3 WIN
CLEM@LVILLE CLEM -120 56.10% 3 LOSS
COL@HOU ANDREJ JAKIMOVSKI PTS + REB + AST - UNDER 15.5 53.70% 2 LOSS
FORD@GWASH FORD +7 53.80% 2 WIN
SEATTLE@ABIL ABIL +6 54.50% 3 WIN
BAMAST@TEXSOU BAMAST -110 55.40% 4 WIN
OHIO@TOLEDO TOLEDO +3 56.70% 4 WIN
UVA@GATECH GATECH +1.5 53.70% 2 WIN
COLO@WVU COLO +7.5 53.20% 2 WIN
USC@RUT USC -115 54.00% 2 WIN
TEXAS@VANDY VANDY -130 56.50% 3 LOSS
BUTLER@PROV BUTLER -115 55.20% 3 WIN
IDAHO@MONTANA MONTANA -6 53.50% 2 WIN
TROY@JMAD TROY -125 55.60% 2 WIN
BELMONT@DRAKE DRAKE -7.5 53.50% 2 LOSS
UCSD@UCDAV UCSD -12.5 53.40% 2 LOSS
SIUE@SEMO SEMO -2.5 54.80% 3 LOSS
ALCORN@ARKPB ARKPB +6.5 56.00% 4 WIN
NORFLK@HOWARD HOWARD +5.5 53.70% 2 LOSS
NKY@CLEVST NKY +4.5 54.40% 3 LOSS
STNFRD@ND STNFRD -125 56.40% 3 LOSS
TENN@OLEMISS OLEMISS +2.5 54.30% 3 WIN
LSALLE@GMASON GMASON -12 54.30% 3 LOSS
PITT@NCST NCST +2.5 56.70% 4 WIN
IND@OREG OREG -6.5 53.60% 2 WIN
FSU@UVA UVA -4 54.40% 3 LOSS
ARK@VANDY ARK +7.5 54.40% 3 WIN
SDGST@UNLV UNLV +2.5 54.10% 3 WIN
EKTY@JVILLE JVILLE -135 58.90% 3 WIN
MANHAT@NIAGARA MANHAT -115 54.70% 3 WIN
MEMP@UAB MEMP -115 54.90% 3 WIN
ILL@MICH MICH -2.5 56.00% 4 LOSS
OKLA@OLEMISS OKLA +7.5 54.50% 3 WIN
ARIZST@UTAH ARIZST +8.5 54.60% 3 LOSS
GC@SEATTLE GC -110 55.00% 3 WIN
PENN@CLMBIA CLMBIA -122 57.50% 4 LOSS
IONA@NIAGARA NIAGARA +1.5 54.30% 3 LOSS
MARIST@SACHRT SACHRT -120 55.40% 3 WIN
CLEVST@WRIGHT CLEVST +1.5 54.30% 3 LOSS
NDAK@STTHOM STTHOM -10 54.30% 3 WIN
USD@WASHST WASHST -12.5 55.20% 4 LOSS
CSBAK@LBEACH CSBAK -130 59.70% 4 WIN
BU@LEHIGH LEHIGH -135 57.70% 3 LOSS
DUQ@LSALLE DUQ -125 56.70% 3 WIN
BYU@ARIZST ARIZST +7.5 54.60% 3 LOSS
UTAHST@BOISE BOISE -4 55.50% 4 WIN