The upcoming NCAA Tournament first-round matchup between the No. 3 seed Iowa State Cyclones and the No. 14 seed Lipscomb Bisons on March 21, 2025, at Fiserv Forum in Milwaukee, Wisconsin, presents an intriguing clash of styles and narratives. Iowa State, boasting a 24-9 record, has been a formidable force in the Big 12 Conference, known for their suffocating defense and balanced offensive attack. Under the guidance of head coach T.J. Otzelberger, the Cyclones have secured two Sweet 16 appearances in the last four seasons and are aiming to advance further this year. Their defense ranks in the top 10 nationally, a testament to their discipline and tactical acumen. Offensively, Iowa State averages 80.4 points per game while allowing 68.1 points, reflecting a positive scoring margin that underscores their two-way proficiency. The team has faced recent challenges with injuries, notably to starting guard Keshon Gilbert, who, averaging 13.4 points and 4.1 assists per game, will be unavailable for the tournament due to a groin injury. However, the anticipated return of starting guard Tamin Lipsey, who has been progressing well in his recovery, is expected to bolster the Cyclones’ backcourt stability. Curtis Jones, leading the team with an average of 17.1 points per game, will be pivotal in maintaining offensive momentum, especially in Gilbert’s absence. Forward Joshua Jefferson’s contribution of 13.0 points and a team-high 7.4 rebounds per game adds a crucial inside presence, complementing the Cyclones’ perimeter-oriented play. Lipscomb enters the tournament with a 25-9 record, having secured the ASUN Conference championship and demonstrating resilience and cohesion under head coach Lennie Acuff. The Bisons’ offense has been particularly potent, averaging over 80 points per game during their current win streak, a notable increase from their regular-season performance.

This surge is attributed to their fast-paced play, efficient shooting, and the versatility of key players. Forward Jacob Ognacevic has been instrumental, leading the team in scoring and providing a dynamic inside-out threat that challenges opposing defenses. The backcourt duo of Will Pruitt and Tommy Murr has been effective in orchestrating the offense, with Pruitt’s playmaking abilities and Murr’s sharpshooting stretching defenses and creating driving lanes. Defensively, Lipscomb emphasizes pressure defense and active hands, aiming to disrupt passing lanes and force turnovers that can ignite their transition game. However, their defensive efficiency has been inconsistent, and facing a disciplined team like Iowa State will require heightened focus and execution. The Bisons’ ability to adapt their defensive schemes, possibly incorporating zone defenses to counter the Cyclones’ perimeter shooting, could be a determining factor in their competitiveness. From a betting perspective, Iowa State is favored by 14.5 points, reflecting expectations of a decisive victory. However, Lipscomb’s 16-14-0 ATS record indicates their capability to cover spreads, particularly as underdogs. The over/under is set at 143.5 points, with Iowa State’s tendency for high-scoring games—evidenced by the total going over in 16 of their games this season—suggesting a potential for a game that exceeds this total. The game’s tempo will be a critical factor; Iowa State’s methodical offense contrasts with Lipscomb’s preference for an up-tempo style. The Cyclones’ ability to control the pace, leveraging their defensive prowess to dictate a slower game, could neutralize the Bisons’ transition opportunities. Conversely, if Lipscomb can impose a faster tempo and capitalize on fast-break opportunities, they may exploit Iowa State’s transitional defense. Rebounding will also play a significant role, with Iowa State’s Joshua Jefferson anchoring the boards against a Lipscomb team that relies on collective rebounding efforts. Second-chance points could swing momentum, making box-out discipline and positioning crucial for both teams. Coaching strategies will be under the spotlight, as Otzelberger’s tournament experience contrasts with Acuff’s first NCAA Tournament appearance with Lipscomb. Adjustments, timeout management, and late-game decision-making will be pivotal, especially if the game remains close in the final minutes. In summary, the Iowa State vs. Lipscomb matchup presents a classic tournament scenario where a higher-seeded team must assert its dominance against a lower-seeded opponent riding a wave of momentum and belief. The Cyclones’ defensive discipline and experience position them as favorites, but the Bisons’ offensive surge and resilience embody the unpredictability that makes March Madness captivating. Fans can anticipate a contest where contrasting styles and strategic nuances converge, offering the potential for both expected outcomes and surprising twists.