Blackhawks vs Sabres Prediction — AI Finds CAN'T MISS NHL Lines & Props (Nov 21)
Updated: 2025-11-19T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Nov 21, 2025
Start Time: 7:00 PM EST
Venue:
Sabres Record:
Blackhawks Record:
OPENING ODDS
CHI Moneyline:
BUF Moneyline:
CHI Spread: 0
BUF Spread:
Over/Under:
CHI
Betting Trends
BUF
Betting Trends
MATCHUP TRENDS
CHI vs. BUF
Best Prop Bet
LIVE NHL ODDS
NHL ODDS COMPARISON
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Chicago vs Buffalo Prediction & Odds:
Free NHL Betting Insights for 11/21/25
Chicago Blackhawks NHL Preview
Credit: USA TODAY/IMAGN
Buffalo Sabres NHL Preview
Chicago vs. Buffalo Prop Picks (AI)
Chicago vs. Buffalo Prediction (AI)
Remi, our AI sports genius, has been pouring over millions of data from every simulation between the Blackhawks and Sabres and using recursive machine learning and impressive AI to crunch the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most watching on the linear correlation of weight human bettors tend to put on Buffalo’s strength factors between a Blackhawks team going up against a possibly healthy Sabres team. In reality, the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our NHL AI picks for FREE now.
Below is our current AI Chicago vs Buffalo picks, computer picks Blackhawks vs Sabres, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| NHL | 11/11 | CLB@SEA | UNLOCK THIS PICK | 1 |
INTEL
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NHL schedule.
Blackhawks Betting Trends
Sabres Betting Trends
Blackhawks vs. Sabres Matchup Trends
Chicago vs. Buffalo Game Info
What time does Chicago vs Buffalo start on November 21, 2025?
Chicago vs Buffalo starts on November 21, 2025 at 7:00 PM EST.
What are the opening odds for Chicago vs Buffalo?
Spread: Buffalo
Moneyline: Chicago , Buffalo
Over/Under:
What are the records for Chicago vs Buffalo?
Chicago: | Buffalo:
What is the AI best bet for Chicago vs Buffalo?
. Prices move—always shop for the best number.
What are Chicago trending bets?
CHI trend:
What are Buffalo trending bets?
BUF trend:
Where can I find AI Picks for Chicago vs Buffalo?
See our latest NHL picks and odds pages for 2025 to compare prices before you bet.
Chicago vs. Buffalo Odds
AI algorithm Remi is pouring through tons of data on each team. In fact, anytime the Chicago vs Buffalo trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme hostile environments seemingly never follow normal, predictable patterns.
Chicago vs Buffalo Opening Odds
CHI Moneyline:
BUF Moneyline:
CHI Spread: 0
BUF Spread:
Over/Under:
Chicago vs Buffalo Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
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In Progress
Winnipeg Jets
Vancouver Canucks
In Progress
Jets
Canucks
|
4
2
|
-10000
+3300
|
-2.5 (-130)
+2.5 (-102)
|
O 7.5 (+230)
U 7.5 (-325)
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In Progress
Columbus Blue Jackets
Seattle Kraken
In Progress
Blue Jackets
Kraken
|
1
1
|
-105
-125
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+1.5 (-3500)
-1.5 (+1400)
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O 3.5 (+420)
U 3.5 (-660)
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Nov 12, 2025 7:10PM EST
New York Rangers
Tampa Bay Lightning
11/12/25 7:10PM
Rangers
Lightning
|
–
–
|
+130
-155
|
+1.5 (-192)
-1.5 (+160)
|
O 5.5 (-130)
U 5.5 (+110)
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|
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Nov 12, 2025 7:40PM EST
Edmonton Oilers
Philadelphia Flyers
11/12/25 7:40PM
Oilers
Flyers
|
–
–
|
-135
+114
|
-1.5 (+180)
+1.5 (-218)
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O 5.5 (-130)
U 5.5 (+110)
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Nov 12, 2025 9:40PM EST
New Jersey Devils
Chicago Blackhawks
11/12/25 9:40PM
Devils
Blackhawks
|
–
–
|
-155
+130
|
-1.5 (+170)
+1.5 (-205)
|
O 6.5 (+105)
U 6.5 (-125)
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NHL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Chicago Blackhawks vs. Buffalo Sabres on November 21, 2025 at .
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NHL odds pages, and compare prices before you place a bet.
| NHL |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| PIT@TOR | OVER 6.5 | 53.5% | 3 | WIN |
| VAN@NSH | OVER 5.5 | 53.9% | 3 | WIN |
| NJ@ANA | ANA +110 | 44.8% | 1 | WIN |
| DET@ANA | DET -100 | 51.5% | 3 | LOSS |
| NYI@CAR | UNDER 6.5 | 54.1% | 4 | LOSS |
| WPG@MIN | WPG -115 | 56.4% | 4 | WIN |
| NYI@BOS | UNDER 6.5 | 55.0% | 3 | LOSS |
| MIN@NYR | OVER 5.5 | 54.2% | 3 | LOSS |
| ANA@CHI | ANA -125 | 56.9% | 3 | LOSS |
| MIN@WAS | WAS -120 | 56.2% | 3 | WIN |
| WPG@PHI | WPG -132 | 56.7% | 3 | WIN |
| NYR@TOR | TOR -133 | 58.6% | 4 | WIN |
| CGY@UTA | OVER 6 | 53.8% | 3 | LOSS |
| OTT@BUF | OTT -108 | 53.1% | 3 | LOSS |
| FLA@DET | AARON EKBLAD OVER 0.5 POINTS | 54.0% | 4 | LOSS |
| LA@MIN | LA -110 | 56.0% | 5 | LOSS |
| STL@VAN | VAN -121 | 54.6% | 4 | LOSS |
| BUF@BOS | BOS -114 | 54.9% | 3 | WIN |
| ANA@SEA | SEA -125 | 54.2% | 3 | WIN |
| ANA@SEA | TROY TERRY OVER 0.5 POINTS | 53.3% | 3 | LOSS |
| BOS@WAS | ALEX OVECHKIN TO SCORE A GOAL | 41.4% | 2 | LOSS |
| FLA@EDM | MATTHEW TKACHUK OVER 0.5 ASSTS | 53.70% | 3 | WIN |
| FLA@EDM | RYAN NUGENT-HOPKINS OVER 1.5 SHOTS ON GOAL | 54.50% | 4 | LOSS |
| EDM@FLA | ALEKSANDER BARKOV UNDER 11.5 FACEOFFS WON | 53.00% | 3 | LOSS |
| EDM@FLA | ALEKSANDER BARKOV UNDER 20.5 MINUTES ON THE ICE | 54.00% | 4 | LOSS |
| EDM@DAL | DAL -110 | 53.80% | 3 | LOSS |
| EDM@DAL | DAL -125 | 56.70% | 3 | WIN |
| TOR@FLA | MAX PACIORETTY UNDER 1.5 SHOTS ON GOAL | 55.60% | 5 | LOSS |
| TOR@FLA | WILLIAM NYLANDER UNDER 2.5 SHOTS ON GOAL | 54.90% | 4 | LOSS |
| CAR@WAS | WAS +140 | 47.70% | 3 | WIN |
| WPG@STL | STL -110 | 54.80% | 4 | WIN |
| WPG@STL | UNDER 5.5 | 55.70% | 4 | LOSS |
| CGY@LA | MACKENZIE WEEGAR OVER 2.5 BLOCKS | 53.10% | 3 | WIN |
| TB@NYR | TB +110 | 49.80% | 3 | LOSS |
| SJ@VAN | ALEXANDER GEORGIEV UNDER 24.5 SAVES | 54.50% | 4 | LOSS |
| BUF@TB | OVER 6.5 | 53.90% | 3 | WIN |
| NYI@PHI | PHI -110 | 54.00% | 3 | WIN |
| LV@EDM | RYAN NUGENT-HOPKINS OVER 1.5 SHOTS ON GOAL | 53.00% | 3 | WIN |
| EDM@ANA | OVER 6 | 54.20% | 3 | LOSS |
| CAR@BOS | OVER 5.5 | 54.00% | 3 | WIN |
| NYR@NJ | NJ -125 | 57.30% | 4 | WIN |
| COL@CLB | OVER 6.5 | 53.80% | 3 | WIN |
| LA@UTA | LA -125 | 54.70% | 3 | WIN |
| WPG@LV | LV -120 | 54.80% | 3 | LOSS |
| MIN@NJ | UNDER 5.5 | 53.80% | 3 | WIN |
| NSH@PHI | PHI -120 | 55.00% | 3 | WIN |
| OTT@BUF | OVER 6 | 54.00% | 3 | LOSS |
| CHI@SJ | CHI +105 | 51.60% | 3 | LOSS |
| WAS@LA | WAS +105 | 51.20% | 3 | LOSS |
| TB@CAR | CAR -130 | 56.40% | 3 | WIN |
| NSH@BOS | BOS -125 | 55.20% | 3 | LOSS |